Klotho / FLGR242 (albumin-bound new tech)
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Response from BLL - IMO very informative. As I said before, I love learning and never settle for answers that are "should be" "probably ok" and the likes.
Here is the response:
Thank you for the thoughtful question, and we’re glad to hear you’ve been pleased with the product.
The two concepts are actually measuring different things. Stability in a vial refers to how well the reconstituted peptide maintains its chemical and physical integrity while being stored. Temperature, time, pH, light, oxidation, and other factors can contribute to degradation, which is why refrigeration is recommended after reconstitution.
A half-life in the body, on the other hand, describes how quickly a compound is cleared or metabolized after it enters a biological system. The environment inside the body is very different from a vial sitting at room temperature. Protein binding, including albumin binding, can affect distribution and can protect a compound from rapid clearance or degradation, thereby extending its circulating half-life.
So, a compound can require refrigerated storage after reconstitution while still having a comparatively long biological half-life at body temperature. The storage-stability timeframe and biological half-life are not directly interchangeable.
Because our products are sold strictly for research use only, we aren't able to provide guidance regarding human administration or individual use. However, I hope this helps clarify the distinction between storage stability and biological half-life. -
I’m sure those of you on the BLL mailing lists have seen the announcements that they are significantly lowering prices for klotho and FLGR242 going forward. For everyone else, regular pricing of $299/2 vials. Much more ‘affordable’ now.
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I’m sure those of you on the BLL mailing lists have seen the announcements that they are significantly lowering prices for klotho and FLGR242 going forward. For everyone else, regular pricing of $299/2 vials. Much more ‘affordable’ now.
I’m sure those of you on the BLL mailing lists have seen the announcements that they are significantly lowering prices for klotho and FLGR242 going forward. For everyone else, regular pricing of $299/2 vials. Much more ‘affordable’ now.
I did not get the email. Thanks for the update though.
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Well, it’s not a secret, so here you go.
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4 week update- I’ve been noticeably stronger in the gym lately and have actually set a few PR’s. Still way more vascular than normal. I’d been averaging 8-10lbs weight loss a month. Since starting FLGR it has slowed to maybe 1-2lbs but my smart scale shows fat decreasing and muscle increasing. Disclaimer: I started enclomaphine around the same time so there’s really no telling which one is doing the heavy lifting but my test went from 677 to 900 on 6.25mg of Enclo daily. Taking 2 vials of slim assist every Sunday. It’s either working, the increased testosterone is working, or is
a top tier placebo. Either way I’m happy thus far -
4 week update- I’ve been noticeably stronger in the gym lately and have actually set a few PR’s. Still way more vascular than normal. I’d been averaging 8-10lbs weight loss a month. Since starting FLGR it has slowed to maybe 1-2lbs but my smart scale shows fat decreasing and muscle increasing. Disclaimer: I started enclomaphine around the same time so there’s really no telling which one is doing the heavy lifting but my test went from 677 to 900 on 6.25mg of Enclo daily. Taking 2 vials of slim assist every Sunday. It’s either working, the increased testosterone is working, or is
a top tier placebo. Either way I’m happy thus far4 week update- I’ve been noticeably stronger in the gym lately and have actually set a few PR’s. Still way more vascular than normal. I’d been averaging 8-10lbs weight loss a month. Since starting FLGR it has slowed to maybe 1-2lbs but my smart scale shows fat decreasing and muscle increasing. Disclaimer: I started enclomaphine around the same time so there’s really no telling which one is doing the heavy lifting but my test went from 677 to 900 on 6.25mg of Enclo daily. Taking 2 vials of slim assist every Sunday. It’s either working, the increased testosterone is working, or is the a top tier placebo. Either way I’m happy thus far
I am also taking enclomiphine but 12.5mg 3x a week and 1 vial of slim assist (2mg FLGR) weekly. It's been 6 weeks for me. Did you titrate up to 2 vials of slim assist or did you just start off at 2 vials? I'm thinking of moving up on it but wondering if I should do 2 vials at once or split it between the week. Interested in hearing your protocol as we seem to be on the same thing.
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Yesterday, JC hosted Mike Farber again who basically answered questions about Alpha-Klotho, FLGR-242, and BioLean, which will soon be available. He also mentioned the drop in price for the signature peptides. I do have the Jamie AI Executive Summary of the talk.
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I wish I bought more of Slim Assist in that deal a little while back. This pricing of 299/2 vials of FLGR242 is way too expensive in comparison to slim assist which came out to $17 a vial for me.
@denti I imagine there may be a holiday special coming up. 'tis the season to be scared and thankful?!
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I wish I bought more of Slim Assist in that deal a little while back. This pricing of 299/2 vials of FLGR242 is way too expensive in comparison to slim assist which came out to $17 a vial for me.
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Really? Link me please.
Edit: Sorry I am dumb. I see you did link me. Thank you.
Edit 2: This comes out to about $32 a vial vs the $17 a couple months back. I think couple months ago it was on sale an then the jayc code on top to drop the price to $17 a vial.
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Been on FLGR for 15 weeks. Started at 2.5mg. After zero change. I upped to 5 the last 4 weeks. Have put on a few pounds of muscle. And FAT. But keep in mind. According to the manufacturer. You have to up your calories 50-75% above BMR. REALLY hard to do. I maintain my 170-200 grams of protein.
Here's what Ive taken into account. I increased the intensity of strength training. Just because I don't want that to be a reason I'm not seeing gains. My Sleep averages 7.5 hours of quality sleep. I eliminated all other peptides. Just to not affect results.
I'm 68. 180# 14% body fat (Dexa every month) been strength training for 50+ years. Retired from the fitness industry. Very disciplined.
My take? Not worth the price. More hype than science (which there is none of) and think I should have gone a HG peptides route or just HGH. Do need to mention I've been on TRT for 8 years and maintain excellent blood markers across the board. Maybe I'm just a non responder?
Good on all of those who claim huge increases in muscle mass after a couple of months. But...until I see MRI scans proving that. Or really know what's in the vials? I'll not continue FLGR-242 -
Quick follow-up on the new Kimera Chems Na Salt-form O-304. It's potent, I'm quite fine on 50-100mg of it vs 400-600mg of the free-acid versions being sold by EVERYONE else. Homework is your friend, once again.
The 5-Amino-1MQ 50mg tabs from QSC are great, one less ting I have to pin and far more cost effective (cost per mg). No negs that I can discern.
Again do your homework. For those who enjoy him, Nick Norwitz has some thought-provoking papers on both. Check his Substack.
I'd suggest both of these are oriented towards those looking to fine-tune what is already a well optimized regimen and body.
My research with SS-31 at 60mg per day, every day, remains ongoing.
@PeptidePete what's your monthly cost for SS-31 @ that dose? Must be a luxury car payment!
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Really? Link me please.
Edit: Sorry I am dumb. I see you did link me. Thank you.
Edit 2: This comes out to about $32 a vial vs the $17 a couple months back. I think couple months ago it was on sale an then the jayc code on top to drop the price to $17 a vial.
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4 week update- I’ve been noticeably stronger in the gym lately and have actually set a few PR’s. Still way more vascular than normal. I’d been averaging 8-10lbs weight loss a month. Since starting FLGR it has slowed to maybe 1-2lbs but my smart scale shows fat decreasing and muscle increasing. Disclaimer: I started enclomaphine around the same time so there’s really no telling which one is doing the heavy lifting but my test went from 677 to 900 on 6.25mg of Enclo daily. Taking 2 vials of slim assist every Sunday. It’s either working, the increased testosterone is working, or is
a top tier placebo. Either way I’m happy thus far4 week update- I’ve been noticeably stronger in the gym lately and have actually set a few PR’s. Still way more vascular than normal. I’d been averaging 8-10lbs weight loss a month. Since starting FLGR it has slowed to maybe 1-2lbs but my smart scale shows fat decreasing and muscle increasing. Disclaimer: I started enclomaphine around the same time so there’s really no telling which one is doing the heavy lifting but my test went from 677 to 900 on 6.25mg of Enclo daily. Taking 2 vials of slim assist every Sunday. It’s either working, the increased testosterone is working, or is
a top tier placebo. Either way I’m happy thus farWow! And....exactly what I would expect
Please update after more weeks. Based on my experience you have 3-4 great months ahead of you.
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