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  3. The Tri-healing protocol for Shoulder and Knee: the tale of 2 lab rats
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The Tri-healing protocol for Shoulder and Knee: the tale of 2 lab rats

Scheduled Pinned Locked Moved Results & Lifestyle
cartalaxbpc-157tb-500
72 Posts 22 Posters 11.1k Views 5 Watching
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  • joeypepsJ Offline
    joeypepsJ Offline
    joeypeps
    wrote last edited by joeypeps
    #2

    Appreciate you sharing your research experience! Happy to hear the results for subject 1. Hoping for a good outcome on RS2 🙏

    1 Reply Last reply
    2
    • C Offline
      C Offline
      Commander
      wrote last edited by
      #3

      You aren’t kidding, my shoulder injury gets better every day. Just from KLOW. But that has the. oC157 and TB500 you take in it.

      Please excuse my typos. Small Phone & Bad Eyes

      1 Reply Last reply
      2
      • WisGal64W Online
        WisGal64W Online
        WisGal64
        wrote last edited by
        #4

        @gym.rat No not IM, pinch the skin, SubQ only. No pain at all.

        “Not a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

        1 Reply Last reply
        1
        • B Offline
          B Offline
          brandenscheidecker
          wrote last edited by
          #5

          were did you find cartalax? I need to add this!

          1 Reply Last reply
          1
          • WisGal64W Online
            WisGal64W Online
            WisGal64
            wrote last edited by
            #6

            @brandenscheidecker flawless compounds, glow aminos and skye peptides are who I have purchased from. Both flawless and glow bumped up testing this week to include sterility and endo.

            “Not a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

            B 1 Reply Last reply
            4
            • Stan DouglasS Offline
              Stan DouglasS Offline
              Stan Douglas
              wrote last edited by
              #7

              I used the same dosage on my rat with a Wolverine mix but went 20 days straight with good results.

              Boutta start a new round tonight but with separate vials. The BPC will be .5 x2 per day as per the Wiki:
              https://www.peptideprotocolwiki.com/peptides/bpc-157

              TB will be 2mg x3 per week for the first week then .75 x2 per week
              https://www.peptideprotocolwiki.com/peptides/tb500

              Planning for the next 6 weeks.

              1 Reply Last reply
              1
              • WisGal64W Online
                WisGal64W Online
                WisGal64
                wrote last edited by
                #8

                @gym.rat. The stinging I keep seeing on posts sounds worse than ghk, gonna steer clear, I’m a big puss when it comes to that kinda pain lol

                “Not a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

                1 Reply Last reply
                0
                • WisGal64W WisGal64

                  @brandenscheidecker flawless compounds, glow aminos and skye peptides are who I have purchased from. Both flawless and glow bumped up testing this week to include sterility and endo.

                  B Offline
                  B Offline
                  beachfun
                  wrote last edited by
                  #9

                  @WisGal64 That’s awesome! I’ve been eyeing cartalax from 2 falls in 2 years on my shoulder. 1 on an icy driveway and another off a 3’ countertop. I direct inject into my shoulder with bpc 3 times a week while still doing GLOW blend and KPV at times.

                  1 Reply Last reply
                  1
                  • B Offline
                    B Offline
                    beachfun
                    wrote last edited by
                    #10

                    @gym.rat Interesting… I never felt anything from 50mg injections of my NAD+. Maybe I need to try “buffered”

                    1 Reply Last reply
                    0
                    • Hammertime65H Offline
                      Hammertime65H Offline
                      Hammertime65
                      wrote last edited by
                      #11

                      After reading all this, I ordered some cartalax from JadeNexus (bogo sale). Will add this to see if it helps. I've been running Klow (30 units) for about 6 weeks, and while it has helped, I still have a lot of pain in the places where I've had surgery. Had my right knee replaced last year and still dealing with issues there. Trying to put off having my left one done because that was the most excruciating pain I've had. Hopefully cartalax with tirz will help. Just saw a youtube video from Dr. Brad that a recent study shows glp1 might actually rebuild cartilage. Fingers crossed.

                      1 Reply Last reply
                      4
                      • WisGal64W WisGal64

                        7/24/2026 Update
                        On day 8 of post-surgery for Rat#1. Tremendous amount of pain and sleepless nights despite meds.
                        The articles I've read seem to be all over the place as far as when the KLOW stack can be introduced. I've read within 72 hours, while others say 2 - 4 weeks. So decided to begin with GHK/KPV on Wednesday(7/22) evening. But unsure of when to introduce BP/TB....

                        **For those who have experience with this, how soon after did you begin post-surgery? **

                        7/16/2026: Rat#1: in surgery as I type this, 2 - 4 wks post surgery will begin another cycle.

                        Rat#2: Will try another cycle in August

                        Update 6/20/26: Rat#1
                        He still feels pretty good, but can't do real heavy lifting which is required for his job.
                        BUT, had a follow up visit with Doc. More Xrays and MRIs, then was referred to Surgeon, which was not a good sign.

                        Prior In 2018 when they opened his right shoulder, surgeon said it looked like hamburger, tissue is shredded, degenerative, not much to work with

                        Fast forward to now: after reviewing the Xrays and MRIs, they still want to do surgery, however, instead of a full shoulder replacement, will do another rotator cuff surgery and remove as much arthritis as they can, collarbone and shoulder are full of it.

                        Surgeon says, the tissue looks good and there is enough to sew to.

                        Whether the Cartalax/TB/BP combo was the reason, or whether his body simply had more regenerative capacity than they expected, IDK, but the fact remains, he now has repairable tissue where he previously had none. My thoughts are that the real evidence will show when they open it up again. Staying positive and hopeful 😄

                        Post surgery, plan to start a Klow stack to help with the healing along with physical therapy. Eventually add in another cycle of Cartalax.

                        As for Rat#2: plan to restart research in the next month or so, I ain't giving it up yet ☺ 🙂


                        Lab Rat #1 — Shoulder OA + Post‑Surgical Pain
                        Background:
                        Two rotator cuff surgeries, arthritis in the joint, severe mobility limits. Couldn’t lift arms overhead, couldn’t hold weight, daily tasks were becoming impossible. Steroid injection in January gave ~2 weeks of relief. Durolane gave ~3 weeks. Advil was basically a food group. Shoulder replacement was on the horizon.

                        📅 February — Research Cycle Begins
                        Baseline:

                        Continued Vitamin D3 (5000 IU daily)

                        Week 1
                        Protocol:
                        BPC‑157: 0.5 mg (Mon–Fri)
                        TB‑500: 0.5 mg (Mon–Fri)
                        Injection sites rotated between bicep and shoulder area

                        No weekend dosing. Notes: No side effects.

                        Week 2
                        Added: Cartalax 1 mg daily
                        Continued BPC‑157 + TB‑500 (same schedule)
                        Notes: No side effects → titrated Cartalax to 2 mg.

                        Weeks 3–4

                        Protocol:
                        BPC‑157: 0.5 mg (Mon–Fri)
                        TB‑500: 0.5 mg (Mon–Fri)
                        Cartalax: 2 mg daily

                        Observation: Pain decreased
                        Could lift arms overhead for the first time in a long time

                        Paused 1 week to assess → benefits maintained.

                        Cycle 2 (Weeks 1–4)

                        Repeated full protocol:
                        Cartalax 2 mg daily
                        BPC‑157 0.5 mg (Mon–Fri)
                        TB‑500 0.5 mg (Mon–Fri)

                        Results: Significant improvement
                        Pain largely resolved
                        Shoulder mobility nearly normal

                        Cycle 3
                        Week 2 and going strong.

                        Functional gains: Building cabinets, Holding tools for long periods, Using saws, Doing tasks previously impossible (couldn’t even hold a coffee pot before)

                        Side effects: None reported across all cycles. Some lab rats are reporting a sting with Cartalax, neither Rat#1 or 2 have experienced this.

                        Summary:
                        Lab Rat #1 = Energizer Bunny.

                        Lab Rat #2 — Knee OA + RA
                        Baseline supplements: NR, NAC, Glutathione(oral Reduced, D3-K2, Astaxanthin,
                        CoQ10 + PQQ reintroduced Week 8

                        Research Cycle — Week 1 (Started Apr 26)
                        Protocol:
                        TB‑500: 0.5 mg
                        BPC‑157: 0.25 mg
                        Cartalax: 1 mg
                        (Evening injections)

                        Note:
                        Lab Rat #2 was cautious with BPC‑157 due to a prior eye‑related reaction in January. Started low. No recurrence of eye issues so far.

                        Day 4 Observations:
                        Knees felt heavy, stiff, and fatigued
                        Literature suggests this can occur due to Collagen II upregulation

                        Morning stiffness slightly improved the next day

                        Increased to 2 mg Cartalax
                        Knees still heavy
                        Stiffness/fullness without visible swelling
                        Monitoring bloodwork

                        Update 3
                        Lab Rat #1 thriving.
                        Lab Rat #2… not so much.

                        Stiffness → pressure → difficulty walking
                        Ice helped temporarily
                        Literature suggests this may be part of early “remodeling,” but unclear
                        Continued cautiously

                        Update 4 (5/16/26)
                        Lab Rat #1 = unstoppable.
                        Lab Rat #2 = officially paused research.
                        Entered a full flare in both knees
                        Walking became extremely difficult
                        Pain escalated beyond “uncomfortable”
                        Waiting for orthopedic evaluation
                        Very disappointed — had high hopes

                        Important note:
                        Lab Rat #2 has RA + OA, which complicates responses and may explain the flare. This shouldn’t discourage others whose physiology is different.

                        Rat#2 ORTHO appointment on 5/17/2026
                        Suspicions confirmed, it's the RA aggravating the OA, and the flare up is due to it was never really calmed down from Dec

                        P Offline
                        P Offline
                        pm24
                        wrote last edited by
                        #12

                        @WisGal64 was Cartalax given in the arm/shoulder also? Or was it given separate in the belly? I’m having the same issue and about to start the same protocol.

                        1 Reply Last reply
                        0
                        • WisGal64W Online
                          WisGal64W Online
                          WisGal64
                          wrote last edited by
                          #13

                          @pm24 Targeted the area of the shoulder and bicep

                          “Not a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

                          1 Reply Last reply
                          0
                          • WisGal64W Online
                            WisGal64W Online
                            WisGal64
                            wrote last edited by
                            #14

                            Wish you the best!

                            “Not a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

                            1 Reply Last reply
                            1
                            • WisGal64W WisGal64

                              7/24/2026 Update
                              On day 8 of post-surgery for Rat#1. Tremendous amount of pain and sleepless nights despite meds.
                              The articles I've read seem to be all over the place as far as when the KLOW stack can be introduced. I've read within 72 hours, while others say 2 - 4 weeks. So decided to begin with GHK/KPV on Wednesday(7/22) evening. But unsure of when to introduce BP/TB....

                              **For those who have experience with this, how soon after did you begin post-surgery? **

                              7/16/2026: Rat#1: in surgery as I type this, 2 - 4 wks post surgery will begin another cycle.

                              Rat#2: Will try another cycle in August

                              Update 6/20/26: Rat#1
                              He still feels pretty good, but can't do real heavy lifting which is required for his job.
                              BUT, had a follow up visit with Doc. More Xrays and MRIs, then was referred to Surgeon, which was not a good sign.

                              Prior In 2018 when they opened his right shoulder, surgeon said it looked like hamburger, tissue is shredded, degenerative, not much to work with

                              Fast forward to now: after reviewing the Xrays and MRIs, they still want to do surgery, however, instead of a full shoulder replacement, will do another rotator cuff surgery and remove as much arthritis as they can, collarbone and shoulder are full of it.

                              Surgeon says, the tissue looks good and there is enough to sew to.

                              Whether the Cartalax/TB/BP combo was the reason, or whether his body simply had more regenerative capacity than they expected, IDK, but the fact remains, he now has repairable tissue where he previously had none. My thoughts are that the real evidence will show when they open it up again. Staying positive and hopeful 😄

                              Post surgery, plan to start a Klow stack to help with the healing along with physical therapy. Eventually add in another cycle of Cartalax.

                              As for Rat#2: plan to restart research in the next month or so, I ain't giving it up yet ☺ 🙂


                              Lab Rat #1 — Shoulder OA + Post‑Surgical Pain
                              Background:
                              Two rotator cuff surgeries, arthritis in the joint, severe mobility limits. Couldn’t lift arms overhead, couldn’t hold weight, daily tasks were becoming impossible. Steroid injection in January gave ~2 weeks of relief. Durolane gave ~3 weeks. Advil was basically a food group. Shoulder replacement was on the horizon.

                              📅 February — Research Cycle Begins
                              Baseline:

                              Continued Vitamin D3 (5000 IU daily)

                              Week 1
                              Protocol:
                              BPC‑157: 0.5 mg (Mon–Fri)
                              TB‑500: 0.5 mg (Mon–Fri)
                              Injection sites rotated between bicep and shoulder area

                              No weekend dosing. Notes: No side effects.

                              Week 2
                              Added: Cartalax 1 mg daily
                              Continued BPC‑157 + TB‑500 (same schedule)
                              Notes: No side effects → titrated Cartalax to 2 mg.

                              Weeks 3–4

                              Protocol:
                              BPC‑157: 0.5 mg (Mon–Fri)
                              TB‑500: 0.5 mg (Mon–Fri)
                              Cartalax: 2 mg daily

                              Observation: Pain decreased
                              Could lift arms overhead for the first time in a long time

                              Paused 1 week to assess → benefits maintained.

                              Cycle 2 (Weeks 1–4)

                              Repeated full protocol:
                              Cartalax 2 mg daily
                              BPC‑157 0.5 mg (Mon–Fri)
                              TB‑500 0.5 mg (Mon–Fri)

                              Results: Significant improvement
                              Pain largely resolved
                              Shoulder mobility nearly normal

                              Cycle 3
                              Week 2 and going strong.

                              Functional gains: Building cabinets, Holding tools for long periods, Using saws, Doing tasks previously impossible (couldn’t even hold a coffee pot before)

                              Side effects: None reported across all cycles. Some lab rats are reporting a sting with Cartalax, neither Rat#1 or 2 have experienced this.

                              Summary:
                              Lab Rat #1 = Energizer Bunny.

                              Lab Rat #2 — Knee OA + RA
                              Baseline supplements: NR, NAC, Glutathione(oral Reduced, D3-K2, Astaxanthin,
                              CoQ10 + PQQ reintroduced Week 8

                              Research Cycle — Week 1 (Started Apr 26)
                              Protocol:
                              TB‑500: 0.5 mg
                              BPC‑157: 0.25 mg
                              Cartalax: 1 mg
                              (Evening injections)

                              Note:
                              Lab Rat #2 was cautious with BPC‑157 due to a prior eye‑related reaction in January. Started low. No recurrence of eye issues so far.

                              Day 4 Observations:
                              Knees felt heavy, stiff, and fatigued
                              Literature suggests this can occur due to Collagen II upregulation

                              Morning stiffness slightly improved the next day

                              Increased to 2 mg Cartalax
                              Knees still heavy
                              Stiffness/fullness without visible swelling
                              Monitoring bloodwork

                              Update 3
                              Lab Rat #1 thriving.
                              Lab Rat #2… not so much.

                              Stiffness → pressure → difficulty walking
                              Ice helped temporarily
                              Literature suggests this may be part of early “remodeling,” but unclear
                              Continued cautiously

                              Update 4 (5/16/26)
                              Lab Rat #1 = unstoppable.
                              Lab Rat #2 = officially paused research.
                              Entered a full flare in both knees
                              Walking became extremely difficult
                              Pain escalated beyond “uncomfortable”
                              Waiting for orthopedic evaluation
                              Very disappointed — had high hopes

                              Important note:
                              Lab Rat #2 has RA + OA, which complicates responses and may explain the flare. This shouldn’t discourage others whose physiology is different.

                              Rat#2 ORTHO appointment on 5/17/2026
                              Suspicions confirmed, it's the RA aggravating the OA, and the flare up is due to it was never really calmed down from Dec

                              S Offline
                              S Offline
                              samsavvysienko
                              wrote last edited by
                              #15

                              @WisGal64 My research subject had similar shoulder pains, could barely lift over head. They just finished an 8 wk cycle of klow. They state it hasn't felt this good in forever & can sleep easier w/out pain. Exciting news! Keep us updated.

                              B 1 Reply Last reply
                              2
                              • S samsavvysienko

                                @WisGal64 My research subject had similar shoulder pains, could barely lift over head. They just finished an 8 wk cycle of klow. They state it hasn't felt this good in forever & can sleep easier w/out pain. Exciting news! Keep us updated.

                                B Offline
                                B Offline
                                beachfun
                                wrote last edited by
                                #16

                                @sam-savvy-sienko Yes!!! Gotta love that! vs what? Surgery? That’s great to hear…

                                1 Reply Last reply
                                1
                                • WisGal64W WisGal64

                                  7/24/2026 Update
                                  On day 8 of post-surgery for Rat#1. Tremendous amount of pain and sleepless nights despite meds.
                                  The articles I've read seem to be all over the place as far as when the KLOW stack can be introduced. I've read within 72 hours, while others say 2 - 4 weeks. So decided to begin with GHK/KPV on Wednesday(7/22) evening. But unsure of when to introduce BP/TB....

                                  **For those who have experience with this, how soon after did you begin post-surgery? **

                                  7/16/2026: Rat#1: in surgery as I type this, 2 - 4 wks post surgery will begin another cycle.

                                  Rat#2: Will try another cycle in August

                                  Update 6/20/26: Rat#1
                                  He still feels pretty good, but can't do real heavy lifting which is required for his job.
                                  BUT, had a follow up visit with Doc. More Xrays and MRIs, then was referred to Surgeon, which was not a good sign.

                                  Prior In 2018 when they opened his right shoulder, surgeon said it looked like hamburger, tissue is shredded, degenerative, not much to work with

                                  Fast forward to now: after reviewing the Xrays and MRIs, they still want to do surgery, however, instead of a full shoulder replacement, will do another rotator cuff surgery and remove as much arthritis as they can, collarbone and shoulder are full of it.

                                  Surgeon says, the tissue looks good and there is enough to sew to.

                                  Whether the Cartalax/TB/BP combo was the reason, or whether his body simply had more regenerative capacity than they expected, IDK, but the fact remains, he now has repairable tissue where he previously had none. My thoughts are that the real evidence will show when they open it up again. Staying positive and hopeful 😄

                                  Post surgery, plan to start a Klow stack to help with the healing along with physical therapy. Eventually add in another cycle of Cartalax.

                                  As for Rat#2: plan to restart research in the next month or so, I ain't giving it up yet ☺ 🙂


                                  Lab Rat #1 — Shoulder OA + Post‑Surgical Pain
                                  Background:
                                  Two rotator cuff surgeries, arthritis in the joint, severe mobility limits. Couldn’t lift arms overhead, couldn’t hold weight, daily tasks were becoming impossible. Steroid injection in January gave ~2 weeks of relief. Durolane gave ~3 weeks. Advil was basically a food group. Shoulder replacement was on the horizon.

                                  📅 February — Research Cycle Begins
                                  Baseline:

                                  Continued Vitamin D3 (5000 IU daily)

                                  Week 1
                                  Protocol:
                                  BPC‑157: 0.5 mg (Mon–Fri)
                                  TB‑500: 0.5 mg (Mon–Fri)
                                  Injection sites rotated between bicep and shoulder area

                                  No weekend dosing. Notes: No side effects.

                                  Week 2
                                  Added: Cartalax 1 mg daily
                                  Continued BPC‑157 + TB‑500 (same schedule)
                                  Notes: No side effects → titrated Cartalax to 2 mg.

                                  Weeks 3–4

                                  Protocol:
                                  BPC‑157: 0.5 mg (Mon–Fri)
                                  TB‑500: 0.5 mg (Mon–Fri)
                                  Cartalax: 2 mg daily

                                  Observation: Pain decreased
                                  Could lift arms overhead for the first time in a long time

                                  Paused 1 week to assess → benefits maintained.

                                  Cycle 2 (Weeks 1–4)

                                  Repeated full protocol:
                                  Cartalax 2 mg daily
                                  BPC‑157 0.5 mg (Mon–Fri)
                                  TB‑500 0.5 mg (Mon–Fri)

                                  Results: Significant improvement
                                  Pain largely resolved
                                  Shoulder mobility nearly normal

                                  Cycle 3
                                  Week 2 and going strong.

                                  Functional gains: Building cabinets, Holding tools for long periods, Using saws, Doing tasks previously impossible (couldn’t even hold a coffee pot before)

                                  Side effects: None reported across all cycles. Some lab rats are reporting a sting with Cartalax, neither Rat#1 or 2 have experienced this.

                                  Summary:
                                  Lab Rat #1 = Energizer Bunny.

                                  Lab Rat #2 — Knee OA + RA
                                  Baseline supplements: NR, NAC, Glutathione(oral Reduced, D3-K2, Astaxanthin,
                                  CoQ10 + PQQ reintroduced Week 8

                                  Research Cycle — Week 1 (Started Apr 26)
                                  Protocol:
                                  TB‑500: 0.5 mg
                                  BPC‑157: 0.25 mg
                                  Cartalax: 1 mg
                                  (Evening injections)

                                  Note:
                                  Lab Rat #2 was cautious with BPC‑157 due to a prior eye‑related reaction in January. Started low. No recurrence of eye issues so far.

                                  Day 4 Observations:
                                  Knees felt heavy, stiff, and fatigued
                                  Literature suggests this can occur due to Collagen II upregulation

                                  Morning stiffness slightly improved the next day

                                  Increased to 2 mg Cartalax
                                  Knees still heavy
                                  Stiffness/fullness without visible swelling
                                  Monitoring bloodwork

                                  Update 3
                                  Lab Rat #1 thriving.
                                  Lab Rat #2… not so much.

                                  Stiffness → pressure → difficulty walking
                                  Ice helped temporarily
                                  Literature suggests this may be part of early “remodeling,” but unclear
                                  Continued cautiously

                                  Update 4 (5/16/26)
                                  Lab Rat #1 = unstoppable.
                                  Lab Rat #2 = officially paused research.
                                  Entered a full flare in both knees
                                  Walking became extremely difficult
                                  Pain escalated beyond “uncomfortable”
                                  Waiting for orthopedic evaluation
                                  Very disappointed — had high hopes

                                  Important note:
                                  Lab Rat #2 has RA + OA, which complicates responses and may explain the flare. This shouldn’t discourage others whose physiology is different.

                                  Rat#2 ORTHO appointment on 5/17/2026
                                  Suspicions confirmed, it's the RA aggravating the OA, and the flare up is due to it was never really calmed down from Dec

                                  J Offline
                                  J Offline
                                  Juan Doe
                                  wrote last edited by Juan Doe
                                  #17

                                  @WisGal64 was there a break between the 1,2, and 3rd cycles? Or was Cartalax taken without breaks?

                                  1 Reply Last reply
                                  0
                                  • WisGal64W Online
                                    WisGal64W Online
                                    WisGal64
                                    wrote last edited by
                                    #18

                                    @juan-doe Cycle 1, took a week break, but then cycles 2 and now 3, no breaks, Cartalax 2mg daily.

                                    “Not a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

                                    1 Reply Last reply
                                    2
                                    • WisGal64W WisGal64

                                      7/24/2026 Update
                                      On day 8 of post-surgery for Rat#1. Tremendous amount of pain and sleepless nights despite meds.
                                      The articles I've read seem to be all over the place as far as when the KLOW stack can be introduced. I've read within 72 hours, while others say 2 - 4 weeks. So decided to begin with GHK/KPV on Wednesday(7/22) evening. But unsure of when to introduce BP/TB....

                                      **For those who have experience with this, how soon after did you begin post-surgery? **

                                      7/16/2026: Rat#1: in surgery as I type this, 2 - 4 wks post surgery will begin another cycle.

                                      Rat#2: Will try another cycle in August

                                      Update 6/20/26: Rat#1
                                      He still feels pretty good, but can't do real heavy lifting which is required for his job.
                                      BUT, had a follow up visit with Doc. More Xrays and MRIs, then was referred to Surgeon, which was not a good sign.

                                      Prior In 2018 when they opened his right shoulder, surgeon said it looked like hamburger, tissue is shredded, degenerative, not much to work with

                                      Fast forward to now: after reviewing the Xrays and MRIs, they still want to do surgery, however, instead of a full shoulder replacement, will do another rotator cuff surgery and remove as much arthritis as they can, collarbone and shoulder are full of it.

                                      Surgeon says, the tissue looks good and there is enough to sew to.

                                      Whether the Cartalax/TB/BP combo was the reason, or whether his body simply had more regenerative capacity than they expected, IDK, but the fact remains, he now has repairable tissue where he previously had none. My thoughts are that the real evidence will show when they open it up again. Staying positive and hopeful 😄

                                      Post surgery, plan to start a Klow stack to help with the healing along with physical therapy. Eventually add in another cycle of Cartalax.

                                      As for Rat#2: plan to restart research in the next month or so, I ain't giving it up yet ☺ 🙂


                                      Lab Rat #1 — Shoulder OA + Post‑Surgical Pain
                                      Background:
                                      Two rotator cuff surgeries, arthritis in the joint, severe mobility limits. Couldn’t lift arms overhead, couldn’t hold weight, daily tasks were becoming impossible. Steroid injection in January gave ~2 weeks of relief. Durolane gave ~3 weeks. Advil was basically a food group. Shoulder replacement was on the horizon.

                                      📅 February — Research Cycle Begins
                                      Baseline:

                                      Continued Vitamin D3 (5000 IU daily)

                                      Week 1
                                      Protocol:
                                      BPC‑157: 0.5 mg (Mon–Fri)
                                      TB‑500: 0.5 mg (Mon–Fri)
                                      Injection sites rotated between bicep and shoulder area

                                      No weekend dosing. Notes: No side effects.

                                      Week 2
                                      Added: Cartalax 1 mg daily
                                      Continued BPC‑157 + TB‑500 (same schedule)
                                      Notes: No side effects → titrated Cartalax to 2 mg.

                                      Weeks 3–4

                                      Protocol:
                                      BPC‑157: 0.5 mg (Mon–Fri)
                                      TB‑500: 0.5 mg (Mon–Fri)
                                      Cartalax: 2 mg daily

                                      Observation: Pain decreased
                                      Could lift arms overhead for the first time in a long time

                                      Paused 1 week to assess → benefits maintained.

                                      Cycle 2 (Weeks 1–4)

                                      Repeated full protocol:
                                      Cartalax 2 mg daily
                                      BPC‑157 0.5 mg (Mon–Fri)
                                      TB‑500 0.5 mg (Mon–Fri)

                                      Results: Significant improvement
                                      Pain largely resolved
                                      Shoulder mobility nearly normal

                                      Cycle 3
                                      Week 2 and going strong.

                                      Functional gains: Building cabinets, Holding tools for long periods, Using saws, Doing tasks previously impossible (couldn’t even hold a coffee pot before)

                                      Side effects: None reported across all cycles. Some lab rats are reporting a sting with Cartalax, neither Rat#1 or 2 have experienced this.

                                      Summary:
                                      Lab Rat #1 = Energizer Bunny.

                                      Lab Rat #2 — Knee OA + RA
                                      Baseline supplements: NR, NAC, Glutathione(oral Reduced, D3-K2, Astaxanthin,
                                      CoQ10 + PQQ reintroduced Week 8

                                      Research Cycle — Week 1 (Started Apr 26)
                                      Protocol:
                                      TB‑500: 0.5 mg
                                      BPC‑157: 0.25 mg
                                      Cartalax: 1 mg
                                      (Evening injections)

                                      Note:
                                      Lab Rat #2 was cautious with BPC‑157 due to a prior eye‑related reaction in January. Started low. No recurrence of eye issues so far.

                                      Day 4 Observations:
                                      Knees felt heavy, stiff, and fatigued
                                      Literature suggests this can occur due to Collagen II upregulation

                                      Morning stiffness slightly improved the next day

                                      Increased to 2 mg Cartalax
                                      Knees still heavy
                                      Stiffness/fullness without visible swelling
                                      Monitoring bloodwork

                                      Update 3
                                      Lab Rat #1 thriving.
                                      Lab Rat #2… not so much.

                                      Stiffness → pressure → difficulty walking
                                      Ice helped temporarily
                                      Literature suggests this may be part of early “remodeling,” but unclear
                                      Continued cautiously

                                      Update 4 (5/16/26)
                                      Lab Rat #1 = unstoppable.
                                      Lab Rat #2 = officially paused research.
                                      Entered a full flare in both knees
                                      Walking became extremely difficult
                                      Pain escalated beyond “uncomfortable”
                                      Waiting for orthopedic evaluation
                                      Very disappointed — had high hopes

                                      Important note:
                                      Lab Rat #2 has RA + OA, which complicates responses and may explain the flare. This shouldn’t discourage others whose physiology is different.

                                      Rat#2 ORTHO appointment on 5/17/2026
                                      Suspicions confirmed, it's the RA aggravating the OA, and the flare up is due to it was never really calmed down from Dec

                                      M Offline
                                      M Offline
                                      MrNatural
                                      wrote last edited by
                                      #19

                                      @WisGal64 Hi, I have been using KLOW (.5, .5, .5 and 2.5 GHK), cartalax (3mg) daily for 2.5 months. Injected at the knees for OA. I rotate KLOW and Cartalax side to side.
                                      Knee caps very sore and medial compartment has the most OA.
                                      I combined this with shockwave therapy. 3 session, will go back for 1-2 sessions after a small break
                                      I could not walk without serious pain. Forget going down the steps. Walking nearly pain free now. I have Synvisc One injections intra articular in the AM at my ortho. So far so good. Still probably gonna have to get a TKR but for now it's been a great relief. Get me through the summer and deal with it in the winter

                                      B 1 Reply Last reply
                                      1
                                      • WisGal64W Online
                                        WisGal64W Online
                                        WisGal64
                                        wrote last edited by
                                        #20

                                        @mrnatural that is wonderful!

                                        Did you experience any heaviness or stiffness in your knees when you first started the Cartalax?

                                        “Not a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

                                        J 1 Reply Last reply
                                        0
                                        • WisGal64W WisGal64

                                          7/24/2026 Update
                                          On day 8 of post-surgery for Rat#1. Tremendous amount of pain and sleepless nights despite meds.
                                          The articles I've read seem to be all over the place as far as when the KLOW stack can be introduced. I've read within 72 hours, while others say 2 - 4 weeks. So decided to begin with GHK/KPV on Wednesday(7/22) evening. But unsure of when to introduce BP/TB....

                                          **For those who have experience with this, how soon after did you begin post-surgery? **

                                          7/16/2026: Rat#1: in surgery as I type this, 2 - 4 wks post surgery will begin another cycle.

                                          Rat#2: Will try another cycle in August

                                          Update 6/20/26: Rat#1
                                          He still feels pretty good, but can't do real heavy lifting which is required for his job.
                                          BUT, had a follow up visit with Doc. More Xrays and MRIs, then was referred to Surgeon, which was not a good sign.

                                          Prior In 2018 when they opened his right shoulder, surgeon said it looked like hamburger, tissue is shredded, degenerative, not much to work with

                                          Fast forward to now: after reviewing the Xrays and MRIs, they still want to do surgery, however, instead of a full shoulder replacement, will do another rotator cuff surgery and remove as much arthritis as they can, collarbone and shoulder are full of it.

                                          Surgeon says, the tissue looks good and there is enough to sew to.

                                          Whether the Cartalax/TB/BP combo was the reason, or whether his body simply had more regenerative capacity than they expected, IDK, but the fact remains, he now has repairable tissue where he previously had none. My thoughts are that the real evidence will show when they open it up again. Staying positive and hopeful 😄

                                          Post surgery, plan to start a Klow stack to help with the healing along with physical therapy. Eventually add in another cycle of Cartalax.

                                          As for Rat#2: plan to restart research in the next month or so, I ain't giving it up yet ☺ 🙂


                                          Lab Rat #1 — Shoulder OA + Post‑Surgical Pain
                                          Background:
                                          Two rotator cuff surgeries, arthritis in the joint, severe mobility limits. Couldn’t lift arms overhead, couldn’t hold weight, daily tasks were becoming impossible. Steroid injection in January gave ~2 weeks of relief. Durolane gave ~3 weeks. Advil was basically a food group. Shoulder replacement was on the horizon.

                                          📅 February — Research Cycle Begins
                                          Baseline:

                                          Continued Vitamin D3 (5000 IU daily)

                                          Week 1
                                          Protocol:
                                          BPC‑157: 0.5 mg (Mon–Fri)
                                          TB‑500: 0.5 mg (Mon–Fri)
                                          Injection sites rotated between bicep and shoulder area

                                          No weekend dosing. Notes: No side effects.

                                          Week 2
                                          Added: Cartalax 1 mg daily
                                          Continued BPC‑157 + TB‑500 (same schedule)
                                          Notes: No side effects → titrated Cartalax to 2 mg.

                                          Weeks 3–4

                                          Protocol:
                                          BPC‑157: 0.5 mg (Mon–Fri)
                                          TB‑500: 0.5 mg (Mon–Fri)
                                          Cartalax: 2 mg daily

                                          Observation: Pain decreased
                                          Could lift arms overhead for the first time in a long time

                                          Paused 1 week to assess → benefits maintained.

                                          Cycle 2 (Weeks 1–4)

                                          Repeated full protocol:
                                          Cartalax 2 mg daily
                                          BPC‑157 0.5 mg (Mon–Fri)
                                          TB‑500 0.5 mg (Mon–Fri)

                                          Results: Significant improvement
                                          Pain largely resolved
                                          Shoulder mobility nearly normal

                                          Cycle 3
                                          Week 2 and going strong.

                                          Functional gains: Building cabinets, Holding tools for long periods, Using saws, Doing tasks previously impossible (couldn’t even hold a coffee pot before)

                                          Side effects: None reported across all cycles. Some lab rats are reporting a sting with Cartalax, neither Rat#1 or 2 have experienced this.

                                          Summary:
                                          Lab Rat #1 = Energizer Bunny.

                                          Lab Rat #2 — Knee OA + RA
                                          Baseline supplements: NR, NAC, Glutathione(oral Reduced, D3-K2, Astaxanthin,
                                          CoQ10 + PQQ reintroduced Week 8

                                          Research Cycle — Week 1 (Started Apr 26)
                                          Protocol:
                                          TB‑500: 0.5 mg
                                          BPC‑157: 0.25 mg
                                          Cartalax: 1 mg
                                          (Evening injections)

                                          Note:
                                          Lab Rat #2 was cautious with BPC‑157 due to a prior eye‑related reaction in January. Started low. No recurrence of eye issues so far.

                                          Day 4 Observations:
                                          Knees felt heavy, stiff, and fatigued
                                          Literature suggests this can occur due to Collagen II upregulation

                                          Morning stiffness slightly improved the next day

                                          Increased to 2 mg Cartalax
                                          Knees still heavy
                                          Stiffness/fullness without visible swelling
                                          Monitoring bloodwork

                                          Update 3
                                          Lab Rat #1 thriving.
                                          Lab Rat #2… not so much.

                                          Stiffness → pressure → difficulty walking
                                          Ice helped temporarily
                                          Literature suggests this may be part of early “remodeling,” but unclear
                                          Continued cautiously

                                          Update 4 (5/16/26)
                                          Lab Rat #1 = unstoppable.
                                          Lab Rat #2 = officially paused research.
                                          Entered a full flare in both knees
                                          Walking became extremely difficult
                                          Pain escalated beyond “uncomfortable”
                                          Waiting for orthopedic evaluation
                                          Very disappointed — had high hopes

                                          Important note:
                                          Lab Rat #2 has RA + OA, which complicates responses and may explain the flare. This shouldn’t discourage others whose physiology is different.

                                          Rat#2 ORTHO appointment on 5/17/2026
                                          Suspicions confirmed, it's the RA aggravating the OA, and the flare up is due to it was never really calmed down from Dec

                                          B Offline
                                          B Offline
                                          Bl8kStr
                                          wrote last edited by
                                          #21

                                          @WisGal64
                                          Having Rotator Cuff surgery last June is what got me into peptides. I started GLOW 4 months after surgery to speed up the healing process and it helped a ton. The day I was ok’d to go back to the gym for extremely light weight and movements I started GLOW, 5 weeks later I was released to go back to normal lifting but just use precaution on weight and not to press anything overhead. 3 months later and switching to BPC-157 and TB-500 I can press overhead and lift with free weights without any limitations. Met the surgeon again last week and he was amazed at my progress and I owe it almost all to peptides

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