The Tri-healing protocol for Shoulder and Knee: the tale of 2 lab rats
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@Eleanor I tested 8mg klow for 10 weeks, off now for some weeks, and started cartalax and ARA recently. All that has really helped because the last few days I've noticed I'm sleeping in 3-4 hour blocks. Previously I constantly tossed and turned because my should, knees, and foot hurt. I've been thinking I must really be tired, but this morning I realized it was the peps doing their thing. Good luck.
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@Hammertime65 That is so good to hear! Thank you! What injection sites are you using?
@Eleanor Not sight specific because I've had 6 surgeries in the last 5 years and they all hurt. So I rotate. At the amount of klow I was doing, the injection site might hurt for a day or 2, especially belly and inner thigh.
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@Eleanor Not sight specific because I've had 6 surgeries in the last 5 years and they all hurt. So I rotate. At the amount of klow I was doing, the injection site might hurt for a day or 2, especially belly and inner thigh.
@Hammertime65 Ouch! Too tender for my bod. Will have to bum it the old fashioned way.
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My Rat is getting it daily, I'm rotating my sites upper leg above my bad knee, and stomach. have been on this protocol for about a month, I also added bpc 157 2x a day am and pm I have noticed the Cartalx has a slight sting to it. I have noticed a reduction in knee pain using the stairs already! It used to hurt going down steps. so plugging away at it!
.75 mg bpc am and pm
.5 mg tb 500 daily pm
.5 mg kpv pm
2mg ghk cu pm
2mg cartalx pm -
@wisgal64 I was so glad to find this thread. Have left knee outer portion giving me fits and right shoulder as well; guess Cartalax is next. Tirz, NAD+, GHKcu (to be replaced by GLOW or KLOW), then Cartalax. Already take the supps you named. Where are you injecting on knee? I know you said biceps on and shoulder, correct? Is knee pin direct or above the area to move with blood flow?
@wisgal64 I was so glad to find this thread. Have left knee outer portion giving me fits and right shoulder as well; guess Cartalax is next. Tirz, NAD+, GHKcu (to be replaced by GLOW or KLOW), then Cartalax. Already take the supps you named. Where are you injecting on knee? I know you said biceps on and shoulder, correct? Is knee pin direct or above the area to move with blood flow?
I missed this one. For my knee I used the area around the knee, not direct. Definitely not into the knee joint itself, too much risk there imo.
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@wisgal64 I was so glad to find this thread. Have left knee outer portion giving me fits and right shoulder as well; guess Cartalax is next. Tirz, NAD+, GHKcu (to be replaced by GLOW or KLOW), then Cartalax. Already take the supps you named. Where are you injecting on knee? I know you said biceps on and shoulder, correct? Is knee pin direct or above the area to move with blood flow?
I missed this one. For my knee I used the area around the knee, not direct. Definitely not into the knee joint itself, too much risk there imo.
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@eleanor unfortunately, my knee problem intensified(affected both knees unfortunately) it had gotten to the point I could hardly walk so I stopped. Cartalax upregulates UC11 (Collagen II) and can cause joint pain for some people(of course I had to be one of them sighh), it's supposed to be temporary but it was too great for me. It triggered an inflammatory response is all I can figure. I ended up going into Ortho, first step, steriod shots to get the inflammation under control, then a gel shot in both. My Ortho reminded me, the RA will aggravate the OA, and my rat probably did not have it under control when I started. She was right, I was banking on the idea that BPC, TB and Cartalax having/being anti-inflammatory I'd be ok(found out that was a bad gamble to take). She did say, if I'm planning to resume "my experiment" be mindful of that aspect, and she wanted updates, in addition, she wanted links to info I had lol
For shoulder, it was Rat#1, inj site was the shoulder area, kept it local.
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@eleanor unfortunately, my knee problem intensified(affected both knees unfortunately) it had gotten to the point I could hardly walk so I stopped. Cartalax upregulates UC11 (Collagen II) and can cause joint pain for some people(of course I had to be one of them sighh), it's supposed to be temporary but it was too great for me. It triggered an inflammatory response is all I can figure. I ended up going into Ortho, first step, steriod shots to get the inflammation under control, then a gel shot in both. My Ortho reminded me, the RA will aggravate the OA, and my rat probably did not have it under control when I started. She was right, I was banking on the idea that BPC, TB and Cartalax having/being anti-inflammatory I'd be ok(found out that was a bad gamble to take). She did say, if I'm planning to resume "my experiment" be mindful of that aspect, and she wanted updates, in addition, she wanted links to info I had lol
For shoulder, it was Rat#1, inj site was the shoulder area, kept it local.
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I have a bad knee I been light footing for a few years. I took GLOw because I got impatient for my Wolverine. Inflammation went away. After the Glow and Wolverine vials my knee is better by 60%. As you can see, I didnt even run any protocol. This time Ill be running them bpc and tb separate. There is a protocol I'm goingnto comit and see how far I can take this knee. I even hit the treadmill without any issues.
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So sorry to hear about rat #2
I have a rat with same problem.
And research seemed to make it more painful.
Would love to hear that any rat got it better.
I still have hope -
WisGal,
You reference eye-related reactions to the BPC, could you be a little specific about that.
I have notice something between a minor itch and minor ache in my eye(s) about 1-2 hours after injection, but also have allergies that I have attributed it to.
Thanks -
Thank you for sharing experiences! I am contemplating some research on the knee joint of my kangaroo that sustained injuries long ago.
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@pmcelveen The first time around when I tried it, I was seeing squiggly flashes of light, I guess some call them floaters. But no pain or itch with it. I later was told by someone on a forum who said that they are an ophthalmologist to make sure I'm getting plenty of H20, especially being on a GLP1, could be electrolyte related as well as being tired.
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Thanks!
Floaters are an issue but pre-peptide. In fact I have trained myself to look around the floaters to see the world
Some squiggly flashes could also be an optical migraine - again, pre-peptide occurences. Rare for me but they do occasionally announce an oncoming real migraine. -
Thanks!
Floaters are an issue but pre-peptide. In fact I have trained myself to look around the floaters to see the world
Some squiggly flashes could also be an optical migraine - again, pre-peptide occurences. Rare for me but they do occasionally announce an oncoming real migraine.@pmcelveen I get those wavy lines like looking thru water on the side of my vision. It doesn't hurt, just annoying. I've never heard of an ocular migraine. I will look into that. Thanks.
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7/24/2026 Update
On day 8 of post-surgery for Rat#1. Tremendous amount of pain and sleepless nights despite meds.
The articles I've read seem to be all over the place as far as when the KLOW stack can be introduced. I've read within 72 hours, while others say 2 - 4 weeks. So decided to begin with GHK/KPV on Wednesday(7/22) evening. But unsure of when to introduce BP/TB....**For those who have experience with this, how soon after did you begin post-surgery? **
7/16/2026: Rat#1: in surgery as I type this, 2 - 4 wks post surgery will begin another cycle.
Rat#2: Will try another cycle in August
Update 6/20/26: Rat#1
He still feels pretty good, but can't do real heavy lifting which is required for his job.
BUT, had a follow up visit with Doc. More Xrays and MRIs, then was referred to Surgeon, which was not a good sign.Prior In 2018 when they opened his right shoulder, surgeon said it looked like hamburger, tissue is shredded, degenerative, not much to work with
Fast forward to now: after reviewing the Xrays and MRIs, they still want to do surgery, however, instead of a full shoulder replacement, will do another rotator cuff surgery and remove as much arthritis as they can, collarbone and shoulder are full of it.
Surgeon says, the tissue looks good and there is enough to sew to.
Whether the Cartalax/TB/BP combo was the reason, or whether his body simply had more regenerative capacity than they expected, IDK, but the fact remains, he now has repairable tissue where he previously had none. My thoughts are that the real evidence will show when they open it up again. Staying positive and hopeful
Post surgery, plan to start a Klow stack to help with the healing along with physical therapy. Eventually add in another cycle of Cartalax.
As for Rat#2: plan to restart research in the next month or so, I ain't giving it up yet
Lab Rat #1 — Shoulder OA + Post‑Surgical Pain
Background:
Two rotator cuff surgeries, arthritis in the joint, severe mobility limits. Couldn’t lift arms overhead, couldn’t hold weight, daily tasks were becoming impossible. Steroid injection in January gave ~2 weeks of relief. Durolane gave ~3 weeks. Advil was basically a food group. Shoulder replacement was on the horizon.
February — Research Cycle Begins
Baseline:Continued Vitamin D3 (5000 IU daily)
Week 1
Protocol:
BPC‑157: 0.5 mg (Mon–Fri)
TB‑500: 0.5 mg (Mon–Fri)
Injection sites rotated between bicep and shoulder areaNo weekend dosing. Notes: No side effects.
Week 2
Added: Cartalax 1 mg daily
Continued BPC‑157 + TB‑500 (same schedule)
Notes: No side effects → titrated Cartalax to 2 mg.Weeks 3–4
Protocol:
BPC‑157: 0.5 mg (Mon–Fri)
TB‑500: 0.5 mg (Mon–Fri)
Cartalax: 2 mg dailyObservation: Pain decreased
Could lift arms overhead for the first time in a long timePaused 1 week to assess → benefits maintained.
Cycle 2 (Weeks 1–4)
Repeated full protocol:
Cartalax 2 mg daily
BPC‑157 0.5 mg (Mon–Fri)
TB‑500 0.5 mg (Mon–Fri)Results: Significant improvement
Pain largely resolved
Shoulder mobility nearly normalCycle 3
Week 2 and going strong.Functional gains: Building cabinets, Holding tools for long periods, Using saws, Doing tasks previously impossible (couldn’t even hold a coffee pot before)
Side effects: None reported across all cycles. Some lab rats are reporting a sting with Cartalax, neither Rat#1 or 2 have experienced this.
Summary:
Lab Rat #1 = Energizer Bunny.Lab Rat #2 — Knee OA + RA
Baseline supplements: NR, NAC, Glutathione(oral Reduced, D3-K2, Astaxanthin,
CoQ10 + PQQ reintroduced Week 8Research Cycle — Week 1 (Started Apr 26)
Protocol:
TB‑500: 0.5 mg
BPC‑157: 0.25 mg
Cartalax: 1 mg
(Evening injections)Note:
Lab Rat #2 was cautious with BPC‑157 due to a prior eye‑related reaction in January. Started low. No recurrence of eye issues so far.Day 4 Observations:
Knees felt heavy, stiff, and fatigued
Literature suggests this can occur due to Collagen II upregulationMorning stiffness slightly improved the next day
Increased to 2 mg Cartalax
Knees still heavy
Stiffness/fullness without visible swelling
Monitoring bloodworkUpdate 3
Lab Rat #1 thriving.
Lab Rat #2… not so much.Stiffness → pressure → difficulty walking
Ice helped temporarily
Literature suggests this may be part of early “remodeling,” but unclear
Continued cautiouslyUpdate 4 (5/16/26)
Lab Rat #1 = unstoppable.
Lab Rat #2 = officially paused research.
Entered a full flare in both knees
Walking became extremely difficult
Pain escalated beyond “uncomfortable”
Waiting for orthopedic evaluation
Very disappointed — had high hopesImportant note:
Lab Rat #2 has RA + OA, which complicates responses and may explain the flare. This shouldn’t discourage others whose physiology is different.Rat#2 ORTHO appointment on 5/17/2026
Suspicions confirmed, it's the RA aggravating the OA, and the flare up is due to it was never really calmed down from Dec
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