The Tri-healing protocol for Shoulder and Knee: the tale of 2 lab rats
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Lab Rat #1 - Has had 2 shoulder surgeries for torn rotator cuff, Arthritis had settled in the joint.
Couldn't raise hands above head, without extreme pain or lift anything, mobility hindered making him unable to perform daily tasks in his profession and at home.
Prior to starting peptide research, In January, tried sterioid injections to calm inflammation. Slight relief, wore off after 2 weeks. Then a shot of Durolane in shoulder joint,
provided some relief for approximately 3 weeks. Was popping Advil like it was candy. Headed for full shoulder replacement.February, research began:
RS continued daily D3 5000iu
Week 1: Injection rotating between bicep and area around shoulder (1 hour before bed)
BPC157 and TB500 - .5mg each Mon - Fri Sat sun offWeek 2:
Continued BPC157 and TB500 .5mg each Mon - Fri
Added Cartlax - 1mg dailyNo side effects, titrated up to 2mg Cartalax
Week 3:
BPC157 .5mg, TB500 .5mg - Mon - Fri
Cartalax 2mg dailyWeek 3:
BPC157 .5mg, TB500 .5mg - Mon - Fri
Cartalax 2mg dailyWeek 4:
BPC157 .5mg, TB500 .5mg - Mon - Fri
Cartalax 2mg dailyStopped for a week to assess: benefits observed, had some pain relief, able to lift shoulders above head.
Repeated full cycle:
Weeks 1-4: Cartalax 2mg daily, .5mg BPC, .5mg TB500More improvement: pain subsided, shoulder mobility almost normal.
Now on into week 2 of 3rd cycle, going really well. To the point, researcher is building cabinets, able to hold and use saws for long periods of time, he's building cabinets.
Honestly, this is a big deal. He went from not able to hold a coffee pot, lift arms above head etc to the above mentioned. Feeling normal againNo side effects to speak of throughout all cycles.
Lab Rat #2: Knee OA/RA
Re-evaluated supplement stack before starting.
Continuing: NR, NAC, Glutathione, D3/K2, Astaxanthin Days 1- 7.
Weeks 8 re-add CoQ10 w/PQQResearch cycle week 1: Evening injection, started Sunday, Apr 26th
.5mg TB500, .25mg BPC157, 1mg Cartalax
Note: lab rat was leary of BPC 157 due to prior trial in January had some strange things happen with eyes and discontinued. Decided to try again due to at the time was also going through a very tired period in life. So starting very low. So far going good with the BPC no weird eye vessels showingDay 4, knee joints felt very heavy and stiffer than normal, and a bit of fatigue observed, this is expected from the literature I've read.
Since it upregulates Collagen II the possibility is there, and given RS's history, assuming most likely.This morning, knees don't feel quite as heavy or stiff, let's see what the day brings. Stay tuned....
UPDATE for #2:
Now at 2mg, Knees still have that heavy feeling, yesterday and today, an uncomfortable stiffness/fullness, they aren't swollen though. Not sure what it means yet, could just be the OA. Did have some bloodwork done, so I'll be checking that thoroughly.Update 3 Lab Rat #1 is doing great, Lab Rat #2 not so much.
The uncomfortable stiffness and heavy feeling, turned into a lot of pressure in the knees, making it difficult to walk Friday evening. Thankfully ice packs helped. Saturday morning (5/9/26) it was a little better. I had more questions than answers so I went down a rabbit hole on these reactions Rat#2 was having. I knew Collagen II could cause joint swelling, so figured this was a part of the puzzle. But how long is the question. According to the literature I've read, it's temporary, and the feelings Rat#2 has in the knees are a sign there is "good remodeling" taking place. I sure hope so! So I'll continue for now
Edit: forgot to add that Lab Rat #2 also includes GHK/KPV in late afternoons 2mg and it's weekly Reta 1mg.
p.s. I had to toss out the GHK/KPV it went bad, so I'll try a new vial, with a fresh bottle of bac to see if it happens again.
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Lab Rat #1 - Has had 2 shoulder surgeries for torn rotator cuff, Arthritis had settled in the joint.
Couldn't raise hands above head, without extreme pain or lift anything, mobility hindered making him unable to perform daily tasks in his profession and at home.
Prior to starting peptide research, In January, tried sterioid injections to calm inflammation. Slight relief, wore off after 2 weeks. Then a shot of Durolane in shoulder joint,
provided some relief for approximately 3 weeks. Was popping Advil like it was candy. Headed for full shoulder replacement.February, research began:
RS continued daily D3 5000iu
Week 1: Injection rotating between bicep and area around shoulder (1 hour before bed)
BPC157 and TB500 - .5mg each Mon - Fri Sat sun offWeek 2:
Continued BPC157 and TB500 .5mg each Mon - Fri
Added Cartlax - 1mg dailyNo side effects, titrated up to 2mg Cartalax
Week 3:
BPC157 .5mg, TB500 .5mg - Mon - Fri
Cartalax 2mg dailyWeek 3:
BPC157 .5mg, TB500 .5mg - Mon - Fri
Cartalax 2mg dailyWeek 4:
BPC157 .5mg, TB500 .5mg - Mon - Fri
Cartalax 2mg dailyStopped for a week to assess: benefits observed, had some pain relief, able to lift shoulders above head.
Repeated full cycle:
Weeks 1-4: Cartalax 2mg daily, .5mg BPC, .5mg TB500More improvement: pain subsided, shoulder mobility almost normal.
Now on into week 2 of 3rd cycle, going really well. To the point, researcher is building cabinets, able to hold and use saws for long periods of time, he's building cabinets.
Honestly, this is a big deal. He went from not able to hold a coffee pot, lift arms above head etc to the above mentioned. Feeling normal againNo side effects to speak of throughout all cycles.
Lab Rat #2: Knee OA/RA
Re-evaluated supplement stack before starting.
Continuing: NR, NAC, Glutathione, D3/K2, Astaxanthin Days 1- 7.
Weeks 8 re-add CoQ10 w/PQQResearch cycle week 1: Evening injection, started Sunday, Apr 26th
.5mg TB500, .25mg BPC157, 1mg Cartalax
Note: lab rat was leary of BPC 157 due to prior trial in January had some strange things happen with eyes and discontinued. Decided to try again due to at the time was also going through a very tired period in life. So starting very low. So far going good with the BPC no weird eye vessels showingDay 4, knee joints felt very heavy and stiffer than normal, and a bit of fatigue observed, this is expected from the literature I've read.
Since it upregulates Collagen II the possibility is there, and given RS's history, assuming most likely.This morning, knees don't feel quite as heavy or stiff, let's see what the day brings. Stay tuned....
UPDATE for #2:
Now at 2mg, Knees still have that heavy feeling, yesterday and today, an uncomfortable stiffness/fullness, they aren't swollen though. Not sure what it means yet, could just be the OA. Did have some bloodwork done, so I'll be checking that thoroughly.Update 3 Lab Rat #1 is doing great, Lab Rat #2 not so much.
The uncomfortable stiffness and heavy feeling, turned into a lot of pressure in the knees, making it difficult to walk Friday evening. Thankfully ice packs helped. Saturday morning (5/9/26) it was a little better. I had more questions than answers so I went down a rabbit hole on these reactions Rat#2 was having. I knew Collagen II could cause joint swelling, so figured this was a part of the puzzle. But how long is the question. According to the literature I've read, it's temporary, and the feelings Rat#2 has in the knees are a sign there is "good remodeling" taking place. I sure hope so! So I'll continue for now
Edit: forgot to add that Lab Rat #2 also includes GHK/KPV in late afternoons 2mg and it's weekly Reta 1mg.
p.s. I had to toss out the GHK/KPV it went bad, so I'll try a new vial, with a fresh bottle of bac to see if it happens again.
@WisGal64 Hi, I have been using KLOW (.5, .5, .5 and 2.5 GHK), cartalax (3mg) daily for 2.5 months. Injected at the knees for OA. I rotate KLOW and Cartalax side to side.
Knee caps very sore and medial compartment has the most OA.
I combined this with shockwave therapy. 3 session, will go back for 1-2 sessions after a small break
I could not walk without serious pain. Forget going down the steps. Walking nearly pain free now. I have Synvisc One injections intra articular in the AM at my ortho. So far so good. Still probably gonna have to get a TKR but for now it's been a great relief. Get me through the summer and deal with it in the winter -
@mrnatural that is wonderful!
Did you experience any heaviness or stiffness in your knees when you first started the Cartalax?
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Lab Rat #1 - Has had 2 shoulder surgeries for torn rotator cuff, Arthritis had settled in the joint.
Couldn't raise hands above head, without extreme pain or lift anything, mobility hindered making him unable to perform daily tasks in his profession and at home.
Prior to starting peptide research, In January, tried sterioid injections to calm inflammation. Slight relief, wore off after 2 weeks. Then a shot of Durolane in shoulder joint,
provided some relief for approximately 3 weeks. Was popping Advil like it was candy. Headed for full shoulder replacement.February, research began:
RS continued daily D3 5000iu
Week 1: Injection rotating between bicep and area around shoulder (1 hour before bed)
BPC157 and TB500 - .5mg each Mon - Fri Sat sun offWeek 2:
Continued BPC157 and TB500 .5mg each Mon - Fri
Added Cartlax - 1mg dailyNo side effects, titrated up to 2mg Cartalax
Week 3:
BPC157 .5mg, TB500 .5mg - Mon - Fri
Cartalax 2mg dailyWeek 3:
BPC157 .5mg, TB500 .5mg - Mon - Fri
Cartalax 2mg dailyWeek 4:
BPC157 .5mg, TB500 .5mg - Mon - Fri
Cartalax 2mg dailyStopped for a week to assess: benefits observed, had some pain relief, able to lift shoulders above head.
Repeated full cycle:
Weeks 1-4: Cartalax 2mg daily, .5mg BPC, .5mg TB500More improvement: pain subsided, shoulder mobility almost normal.
Now on into week 2 of 3rd cycle, going really well. To the point, researcher is building cabinets, able to hold and use saws for long periods of time, he's building cabinets.
Honestly, this is a big deal. He went from not able to hold a coffee pot, lift arms above head etc to the above mentioned. Feeling normal againNo side effects to speak of throughout all cycles.
Lab Rat #2: Knee OA/RA
Re-evaluated supplement stack before starting.
Continuing: NR, NAC, Glutathione, D3/K2, Astaxanthin Days 1- 7.
Weeks 8 re-add CoQ10 w/PQQResearch cycle week 1: Evening injection, started Sunday, Apr 26th
.5mg TB500, .25mg BPC157, 1mg Cartalax
Note: lab rat was leary of BPC 157 due to prior trial in January had some strange things happen with eyes and discontinued. Decided to try again due to at the time was also going through a very tired period in life. So starting very low. So far going good with the BPC no weird eye vessels showingDay 4, knee joints felt very heavy and stiffer than normal, and a bit of fatigue observed, this is expected from the literature I've read.
Since it upregulates Collagen II the possibility is there, and given RS's history, assuming most likely.This morning, knees don't feel quite as heavy or stiff, let's see what the day brings. Stay tuned....
UPDATE for #2:
Now at 2mg, Knees still have that heavy feeling, yesterday and today, an uncomfortable stiffness/fullness, they aren't swollen though. Not sure what it means yet, could just be the OA. Did have some bloodwork done, so I'll be checking that thoroughly.Update 3 Lab Rat #1 is doing great, Lab Rat #2 not so much.
The uncomfortable stiffness and heavy feeling, turned into a lot of pressure in the knees, making it difficult to walk Friday evening. Thankfully ice packs helped. Saturday morning (5/9/26) it was a little better. I had more questions than answers so I went down a rabbit hole on these reactions Rat#2 was having. I knew Collagen II could cause joint swelling, so figured this was a part of the puzzle. But how long is the question. According to the literature I've read, it's temporary, and the feelings Rat#2 has in the knees are a sign there is "good remodeling" taking place. I sure hope so! So I'll continue for now
Edit: forgot to add that Lab Rat #2 also includes GHK/KPV in late afternoons 2mg and it's weekly Reta 1mg.
p.s. I had to toss out the GHK/KPV it went bad, so I'll try a new vial, with a fresh bottle of bac to see if it happens again.
@WisGal64
Having Rotator Cuff surgery last June is what got me into peptides. I started GLOW 4 months after surgery to speed up the healing process and it helped a ton. The day I was ok’d to go back to the gym for extremely light weight and movements I started GLOW, 5 weeks later I was released to go back to normal lifting but just use precaution on weight and not to press anything overhead. 3 months later and switching to BPC-157 and TB-500 I can press overhead and lift with free weights without any limitations. Met the surgeon again last week and he was amazed at my progress and I owe it almost all to peptides -
Any update on your progress? How is Cartalax treating you? I'm particularly interested in the arthritis symptoms since I'm planning to take Cartalax strictly for this reason as I have severe big toe arthritis from an old soccer injury. I have to have a fusion or joint replacement at some point, but I'm too young at this moment. Praying cartalax has some type of positive effect against osteoarthritis.
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To preface my comments, I had/have two torn shoulders. I would suggest adding MSM, Vit. C, and Hyaluronic Acid. It's important to provide your body with the raw materials to help recreate everything. Additionally, I ran KLOW, Cartalax, with the supplements previously mentioned and it has made a huge difference. I even fell off a ladder and landed on my elbow and my ribs hurt, but my shoulder was fine. I'm doing the same thing again in a few weeks.
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To preface my comments, I had/have two torn shoulders. I would suggest adding MSM, Vit. C, and Hyaluronic Acid. It's important to provide your body with the raw materials to help recreate everything. Additionally, I ran KLOW, Cartalax, with the supplements previously mentioned and it has made a huge difference. I even fell off a ladder and landed on my elbow and my ribs hurt, but my shoulder was fine. I'm doing the same thing again in a few weeks.
@theckman80 said in The Tri-healing protocol for Shoulder and Knee: the tale of 2 lab rats:
To preface my comments, I had/have two torn shoulders. I would suggest adding MSM, Vit. C, and Hyaluronic Acid. It's important to provide your body with the raw materials to help recreate everything. Additionally, I ran KLOW, Cartalax, with the supplements previously mentioned and it has made a huge difference. I even fell off a ladder and landed on my elbow and my ribs hurt, but my shoulder was fine. I'm doing the same thing again in a few weeks.
Thanks for this. I just picked up some MSM this week, I'll look into the other 2, I do recall hearing about HA in the past.
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Any update on your progress? How is Cartalax treating you? I'm particularly interested in the arthritis symptoms since I'm planning to take Cartalax strictly for this reason as I have severe big toe arthritis from an old soccer injury. I have to have a fusion or joint replacement at some point, but I'm too young at this moment. Praying cartalax has some type of positive effect against osteoarthritis.
@gym.rat said in The Tri-healing protocol for Shoulder and Knee: the tale of 2 lab rats:
Any update on your progress? How is Cartalax treating you? I'm particularly interested in the arthritis symptoms since I'm planning to take Cartalax strictly for this reason as I have severe big toe arthritis from an old soccer injury. I have to have a fusion or joint replacement at some point, but I'm too young at this moment. Praying cartalax has some type of positive effect against osteoarthritis.
I added an update at the top. If it looks too messy, let me know and I'll revise it
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@mrnatural that is wonderful!
Did you experience any heaviness or stiffness in your knees when you first started the Cartalax?
@WisGal64 I'm glad this came up. I am feeling a little near pining site (near left shoulder). But nothing serious.
Also, When pinning, I find the syringe is a little more resistant.
As if Cartalax is a little less, I want to say, "lubricating" on the syringe compared to 157 or TB4. -
To preface my comments, I had/have two torn shoulders. I would suggest adding MSM, Vit. C, and Hyaluronic Acid. It's important to provide your body with the raw materials to help recreate everything. Additionally, I ran KLOW, Cartalax, with the supplements previously mentioned and it has made a huge difference. I even fell off a ladder and landed on my elbow and my ribs hurt, but my shoulder was fine. I'm doing the same thing again in a few weeks.
@theckman80 I will look into it asap. Thanks
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@WisGal64 I'm glad this came up. I am feeling a little near pining site (near left shoulder). But nothing serious.
Also, When pinning, I find the syringe is a little more resistant.
As if Cartalax is a little less, I want to say, "lubricating" on the syringe compared to 157 or TB4.@Juan-Doe said in The Tri-healing protocol for Shoulder and Knee: the tale of 2 lab rats:
@WisGal64 I'm glad this came up. I am feeling a little near pining site (near left shoulder). But nothing serious.
Also, When pinning, I find the syringe is a little more resistant.
As if Cartalax is a little less, I want to say, "lubricating" on the syringe compared to 157 or TB4.Yes I did notice that with the shoulder area, we thought it was due to scar tissue from previous surgeries or rat#1 just has tough skin lol
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@Juan-Doe said in The Tri-healing protocol for Shoulder and Knee: the tale of 2 lab rats:
@WisGal64 I'm glad this came up. I am feeling a little near pining site (near left shoulder). But nothing serious.
Also, When pinning, I find the syringe is a little more resistant.
As if Cartalax is a little less, I want to say, "lubricating" on the syringe compared to 157 or TB4.Yes I did notice that with the shoulder area, we thought it was due to scar tissue from previous surgeries or rat#1 just has tough skin lol
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To preface my comments, I had/have two torn shoulders. I would suggest adding MSM, Vit. C, and Hyaluronic Acid. It's important to provide your body with the raw materials to help recreate everything. Additionally, I ran KLOW, Cartalax, with the supplements previously mentioned and it has made a huge difference. I even fell off a ladder and landed on my elbow and my ribs hurt, but my shoulder was fine. I'm doing the same thing again in a few weeks.
@theckman80 After doing my own research, I ordered msm and hyaluronic acid (already take vit. c) and should be in soon. Thanks
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@Juan-Doe said in The Tri-healing protocol for Shoulder and Knee: the tale of 2 lab rats:
@WisGal64 As in takes a little more effort to push the syringe plunger.
Oh you mean like the pep is thicker?
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@theckman80 After doing my own research, I ordered msm and hyaluronic acid (already take vit. c) and should be in soon. Thanks
@Juan-Doe that is great! I hope you get as good, if not better results than I did. I (my wife) injected the KLOW and Cartalax sub q on each side. I know for the bpc, it can make a difference where you inject, but i wanted to be as sure as possible. The idea was, BPC'157 for better blood flow into the cartridge. Tb-500 for creatinine better/more collagen and extra cellular matrix. GHK-Cu for gene expression and all the other cool stuff it does. KPV for reduced inflammation. MSM/HA/Vit C to provide the building blocks for the collagen/cartridge. And Cartalax for as the bioregulator to turn on chondrocyte production/gene expression.
I will say, taking the MSM/HA/Vit C in the morning and the shots at jight seemed like a good idea to me. It takes time to breakout all down and have it be available. Additionally, Vit-C and GHK-Cu are supposed to be taken at different times when applying topicly, soni figured id play it safe with the pills/injections.
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To preface my comments, I had/have two torn shoulders. I would suggest adding MSM, Vit. C, and Hyaluronic Acid. It's important to provide your body with the raw materials to help recreate everything. Additionally, I ran KLOW, Cartalax, with the supplements previously mentioned and it has made a huge difference. I even fell off a ladder and landed on my elbow and my ribs hurt, but my shoulder was fine. I'm doing the same thing again in a few weeks.
@theckman80 what is the dosing protocol for the hyaluronic acid? is it sub Q or oral?
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@theckman80 what is the dosing protocol for the hyaluronic acid? is it sub Q or oral?
@brandenscheidecker I took 600mg of low molecular weight HA per day oral route (PO). I've continued to take that same amount. The best way to take it would be in the joint and high molecular weight, but that would be gnarly! So, low molecular weight PO.is the way to go as far as I've seen.
