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MOTS-c reaction….strange

Scheduled Pinned Locked Moved Peptide Discussion
mots-c
48 Posts 21 Posters 5.7k Views 2 Watching
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  • C Offline
    C Offline
    Commander
    wrote last edited by
    #15

    I tried adding in NAD to the Mots-C, I didn’t notice a difference . I am hoping the SS-31 is different

    Please excuse my typos. Small Phone & Bad Eyes

    1 Reply Last reply
    1
    • L Offline
      L Offline
      Lady Hamilton
      wrote last edited by
      #16

      Oh my goodness, I was just about to type a post about this… I was researching 5mg every 3 days (2/3 times a week) my first two 10mg vials, all good no problem, no reaction. So, I thought I’d buy a higher concentration 40mg, diluted with 2ml BAC water - what the hell! Huge itchy welts, which have lasted a week so far! I was so worried, I thought I might have to see a medical professional. But, I think they’re calming down, phew. I just don’t understand why this happened. It’s either the following:

      1. Poor quality peptide, although the supplier claims to third party test - COA was Janoshik, which I checked direct with Janoshik.
      2. Higher concentration
      3. BAC water, although I used a new bottle of Hospira
      4. If this is my genuine reaction to MOTS-C, we’re the first two vials MOTS-C?!

      What are people’s thoughts? Should I try a lower dose or will I just get smaller itchy welts?

      Thanks for any advice

      1 Reply Last reply
      0
      • S Offline
        S Offline
        Shaqdiesel
        wrote last edited by
        #17

        Sounds like it may be due to the higher concentration per ml of BAC water that may have done it for you. At least that is the variable that sticks out to me.

        L 1 Reply Last reply
        4
        • J Online
          J Online
          jackiee
          wrote last edited by
          #18

          Alright, today I went back to my "normal" 3.33mg injection 3X per week. I skipped Monday. The welts from last week have subsided and it has been 2 hours since my pin today and......nothing so far!!

          L 1 Reply Last reply
          3
          • S Shaqdiesel

            Sounds like it may be due to the higher concentration per ml of BAC water that may have done it for you. At least that is the variable that sticks out to me.

            L Offline
            L Offline
            Lady Hamilton
            wrote last edited by
            #19

            Hi @Shaqdiesel Yeah, that’s the conclusion I’ve come to, 100% a histamine response. After looking at chat rooms and YT, it seems my experience is quite common with MOTS-C. I’ll have to go back to 10mg vials.

            1 Reply Last reply
            3
            • J jackiee

              Alright, today I went back to my "normal" 3.33mg injection 3X per week. I skipped Monday. The welts from last week have subsided and it has been 2 hours since my pin today and......nothing so far!!

              L Offline
              L Offline
              Lady Hamilton
              wrote last edited by
              #20

              @jackiew1 Hey, glad it worked out for you. How confusing though, you’d think you’d be fine with a lower dose daily.

              1 Reply Last reply
              1
              • M Offline
                M Offline
                marcoxd
                wrote last edited by marcoxd
                #21

                Pinned the first dose into my subject today. The reaction is very similar to the SS31 reaction. Turns warm, itchy and red almost immediately. the area spreads out left to right on my stomach perhaps 1 to 1.5 inches. and then up and down half an inch or so. But within 1 hour its gone. AI says its most likely not even a histamine reaction but just a local cell reaction to the peptide itself.

                But this was just the first pin which was a baby dose (0.5mg) at 10mg/3ml dilution.

                RandyR O Robot BabylonR 3 Replies Last reply
                1
                • M marcoxd

                  Pinned the first dose into my subject today. The reaction is very similar to the SS31 reaction. Turns warm, itchy and red almost immediately. the area spreads out left to right on my stomach perhaps 1 to 1.5 inches. and then up and down half an inch or so. But within 1 hour its gone. AI says its most likely not even a histamine reaction but just a local cell reaction to the peptide itself.

                  But this was just the first pin which was a baby dose (0.5mg) at 10mg/3ml dilution.

                  RandyR Offline
                  RandyR Offline
                  Randy
                  wrote last edited by
                  #22

                  @marcoxd Thats a warning sign. This ones probably not for you.

                  "If it doesnt come in a needle. It doesn't work"

                  M 1 Reply Last reply
                  2
                  • M marcoxd

                    Pinned the first dose into my subject today. The reaction is very similar to the SS31 reaction. Turns warm, itchy and red almost immediately. the area spreads out left to right on my stomach perhaps 1 to 1.5 inches. and then up and down half an inch or so. But within 1 hour its gone. AI says its most likely not even a histamine reaction but just a local cell reaction to the peptide itself.

                    But this was just the first pin which was a baby dose (0.5mg) at 10mg/3ml dilution.

                    O Offline
                    O Offline
                    Omochi05
                    wrote last edited by
                    #23

                    @marcoxd I had a similar reaction with 10u/1mg, besides just being weird to see I haven’t had any other adverse side effects happens. Usually happens every time but goes completely away in 3-4 hours.

                    1 Reply Last reply
                    0
                    • J Online
                      J Online
                      jackiee
                      wrote last edited by
                      #24

                      The weird thing about mine is, I am fine taking 3.33mg three times per week. But taking 1.5mg every day caused a reaction, starting on the 5th day.

                      1 Reply Last reply
                      -1
                      • Stan DouglasS Offline
                        Stan DouglasS Offline
                        Stan Douglas
                        wrote last edited by
                        #25

                        Instead of dropping dosage in my uniratosaur I doubled the bac water.
                        Instead of 25us it was still 5mg but at 50u this morning and I have no itching, swelling, space maggots spewing out, or any involuntary traversment of time to report at this hour.

                        L 1 Reply Last reply
                        3
                        • Stan DouglasS Stan Douglas

                          Instead of dropping dosage in my uniratosaur I doubled the bac water.
                          Instead of 25us it was still 5mg but at 50u this morning and I have no itching, swelling, space maggots spewing out, or any involuntary traversment of time to report at this hour.

                          L Offline
                          L Offline
                          Lady Hamilton
                          wrote last edited by
                          #26

                          @Stan-Douglas Space maggots! 😂
                          I’ve just heavily diluted mine too, fingers crossed 🤞🏻

                          1 Reply Last reply
                          1
                          • mrjoshua44M Offline
                            mrjoshua44M Offline
                            mrjoshua44
                            wrote last edited by
                            #27

                            One thing you could try, and this goes for SS-31 as well. Try using Bacteriostatic 0.9% Sodium Chloride to reconstitute your MOTS-c. It just might help get rid of the reaction you're having.

                            IMG_0711.jpeg

                            C 1 Reply Last reply
                            1
                            • Stan DouglasS Offline
                              Stan DouglasS Offline
                              Stan Douglas
                              wrote last edited by
                              #28

                              @mrjoshua44
                              You're reconstituting with that or diluting it?

                              mrjoshua44M 1 Reply Last reply
                              1
                              • Stan DouglasS Stan Douglas

                                @mrjoshua44
                                You're reconstituting with that or diluting it?

                                mrjoshua44M Offline
                                mrjoshua44M Offline
                                mrjoshua44
                                wrote last edited by
                                #29

                                @Stan-Douglas Reconstituting just like you would with regular BAC water.

                                1 Reply Last reply
                                1
                                • mrjoshua44M mrjoshua44

                                  One thing you could try, and this goes for SS-31 as well. Try using Bacteriostatic 0.9% Sodium Chloride to reconstitute your MOTS-c. It just might help get rid of the reaction you're having.

                                  IMG_0711.jpeg

                                  C Offline
                                  C Offline
                                  Commander
                                  wrote last edited by
                                  #30

                                  @mrjoshua44 said in MOTS-c reaction….strange:

                                  One thing you could try, and this goes for SS-31 as well. Try using Bacteriostatic 0.9% Sodium Chloride to reconstitute your MOTS-c. It just might help get rid of the reaction you're having.

                                  IMG_0711.jpeg

                                  Why does using this help?

                                  Please excuse my typos. Small Phone & Bad Eyes

                                  mrjoshua44M 1 Reply Last reply
                                  0
                                  • C Commander

                                    @mrjoshua44 said in MOTS-c reaction….strange:

                                    One thing you could try, and this goes for SS-31 as well. Try using Bacteriostatic 0.9% Sodium Chloride to reconstitute your MOTS-c. It just might help get rid of the reaction you're having.

                                    IMG_0711.jpeg

                                    Why does using this help?

                                    mrjoshua44M Offline
                                    mrjoshua44M Offline
                                    mrjoshua44
                                    wrote last edited by
                                    #31

                                    @Commander The sodium chloride content makes the solution isotonic to the body, which significantly reduces the injection-site stinging, welting, and localized irritation that many users experience with plain bacteriostatic water.

                                    Stan DouglasS 1 Reply Last reply
                                    2
                                    • mrjoshua44M mrjoshua44

                                      @Commander The sodium chloride content makes the solution isotonic to the body, which significantly reduces the injection-site stinging, welting, and localized irritation that many users experience with plain bacteriostatic water.

                                      Stan DouglasS Offline
                                      Stan DouglasS Offline
                                      Stan Douglas
                                      wrote last edited by
                                      #32

                                      @mrjoshua44
                                      I have a bottle on the way thanks to your post but
                                      why don't we use this for all our peps then? It's about the same price a regular BW.

                                      mrjoshua44M 1 Reply Last reply
                                      1
                                      • Stan DouglasS Stan Douglas

                                        @mrjoshua44
                                        I have a bottle on the way thanks to your post but
                                        why don't we use this for all our peps then? It's about the same price a regular BW.

                                        mrjoshua44M Offline
                                        mrjoshua44M Offline
                                        mrjoshua44
                                        wrote last edited by
                                        #33

                                        @Stan-Douglas some peptides don't do well the salts so for those use regular BAC water.

                                        1 Reply Last reply
                                        1
                                        • RandyR Randy

                                          @marcoxd Thats a warning sign. This ones probably not for you.

                                          M Offline
                                          M Offline
                                          marcoxd
                                          wrote last edited by marcoxd
                                          #34

                                          @Randy Interesting, isnt a temp injection site itch a common reaction for mots-c not necessarily an indication of the peptide intolerance? Both ss31 and mots-c give me this reaction. It doesnt get worse with increased injections or higher doses. I've researched ss31 atleast 15 pins at this point and titrated up initially without change to the reaction itself, and mots-c i've done 3 pins. It lasts generally no longer than 30 minutes the redness/itching, its pretty mild itchiness too. Its like once its absorbed the local reaction immediately goes away.

                                          I've heard of people getting welts and continuous pinning escalated it. But are welts and light injection site reactions the same kind of "warning"? I'd treat welts or reactions that dont clear immediately quite differently.

                                          1 Reply Last reply
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