MOTS-c reaction….strange
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Instead of dropping dosage in my uniratosaur I doubled the bac water.
Instead of 25us it was still 5mg but at 50u this morning and I have no itching, swelling, space maggots spewing out, or any involuntary traversment of time to report at this hour.@Stan-Douglas Space maggots!
I’ve just heavily diluted mine too, fingers crossed
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One thing you could try, and this goes for SS-31 as well. Try using Bacteriostatic 0.9% Sodium Chloride to reconstitute your MOTS-c. It just might help get rid of the reaction you're having.
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@mrjoshua44
You're reconstituting with that or diluting it? -
@mrjoshua44
You're reconstituting with that or diluting it?@Stan-Douglas Reconstituting just like you would with regular BAC water.
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One thing you could try, and this goes for SS-31 as well. Try using Bacteriostatic 0.9% Sodium Chloride to reconstitute your MOTS-c. It just might help get rid of the reaction you're having.
@mrjoshua44 said in MOTS-c reaction….strange:
One thing you could try, and this goes for SS-31 as well. Try using Bacteriostatic 0.9% Sodium Chloride to reconstitute your MOTS-c. It just might help get rid of the reaction you're having.
Why does using this help?
Please excuse my typos. Small Phone & Bad Eyes
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@mrjoshua44 said in MOTS-c reaction….strange:
One thing you could try, and this goes for SS-31 as well. Try using Bacteriostatic 0.9% Sodium Chloride to reconstitute your MOTS-c. It just might help get rid of the reaction you're having.
Why does using this help?
@Commander The sodium chloride content makes the solution isotonic to the body, which significantly reduces the injection-site stinging, welting, and localized irritation that many users experience with plain bacteriostatic water.
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@Commander The sodium chloride content makes the solution isotonic to the body, which significantly reduces the injection-site stinging, welting, and localized irritation that many users experience with plain bacteriostatic water.
@mrjoshua44
I have a bottle on the way thanks to your post but
why don't we use this for all our peps then? It's about the same price a regular BW. -
@mrjoshua44
I have a bottle on the way thanks to your post but
why don't we use this for all our peps then? It's about the same price a regular BW.@Stan-Douglas some peptides don't do well the salts so for those use regular BAC water.
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@Randy Interesting, isnt a temp injection site itch a common reaction for mots-c not necessarily an indication of the peptide intolerance? Both ss31 and mots-c give me this reaction. It doesnt get worse with increased injections or higher doses. I've researched ss31 atleast 15 pins at this point and titrated up initially without change to the reaction itself, and mots-c i've done 3 pins. It lasts generally no longer than 30 minutes the redness/itching, its pretty mild itchiness too. Its like once its absorbed the local reaction immediately goes away.
I've heard of people getting welts and continuous pinning escalated it. But are welts and light injection site reactions the same kind of "warning"? I'd treat welts or reactions that dont clear immediately quite differently.
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SS31 we have human data on. MOTS-c we have a bunch of influencers peddling affiliate codes with neck tattoos. One thing I keep seeing over and over again is anaphylaxis with mots. I have yet to see someone on reddit or otherwise blame ss31 for that. My point is be careful. MOTS-c can cause severe allergic reactions (same with cjc1295). This research is not without risk.
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SS31 we have human data on. MOTS-c we have a bunch of influencers peddling affiliate codes with neck tattoos. One thing I keep seeing over and over again is anaphylaxis with mots. I have yet to see someone on reddit or otherwise blame ss31 for that. My point is be careful. MOTS-c can cause severe allergic reactions (same with cjc1295). This research is not without risk.
SS31 we have human data on. MOTS-c we have a bunch of influencers peddling affiliate codes with neck tattoos. One thing I keep seeing over and over again is anaphylaxis with mots. I have yet to see someone on reddit or otherwise blame ss31 for that. My point is be careful. MOTS-c can cause severe allergic reactions (same with cjc1295). This research is not without risk.
Word to the wise...and WTF with all the GD tattoos? How do folks claim to be all about maximizing a healthy body and then inject toxic inks into it? Makes zero sense.
Asked my PCP for a EpiPen prescription justttttt to be prepared if ever needed. Peace of mind well worth the price (the co-pay is obscene).
With that said, man I used to get ISR to the MOTS but I never do any longer.
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SS31 we have human data on. MOTS-c we have a bunch of influencers peddling affiliate codes with neck tattoos. One thing I keep seeing over and over again is anaphylaxis with mots. I have yet to see someone on reddit or otherwise blame ss31 for that. My point is be careful. MOTS-c can cause severe allergic reactions (same with cjc1295). This research is not without risk.
Word to the wise...and WTF with all the GD tattoos? How do folks claim to be all about maximizing a healthy body and then inject toxic inks into it? Makes zero sense.
Asked my PCP for a EpiPen prescription justttttt to be prepared if ever needed. Peace of mind well worth the price (the co-pay is obscene).
With that said, man I used to get ISR to the MOTS but I never do any longer.
I injected a lot slower today, click for click, and got no reaction anymore on neither ss31 nor mots-c. Perhaps i just react differently to cationic peptides.
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I injected a lot slower today, click for click, and got no reaction anymore on neither ss31 nor mots-c. Perhaps i just react differently to cationic peptides.
I injected a lot slower today, click for click, and got no reaction anymore on neither ss31 nor mots-c. Perhaps i just react differently to cationic peptides.
I preloaded with antihistamine for several months as I built up a tolerance to MOTS. Never tried slowing the injection but doesn't hurt to try.
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@gym.rat No it is not. Here's what you should use for inhalation and nasal applications.
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@gym.rat No it is not. Here's what you should use for inhalation and nasal applications.
@mrjoshua44 I was under impression that adding peptides to saline solutions may be harmful to the molecules, also isn't it irritable for nasal tissue. I am planning to make a nasal solution myself so I bought USP sterile water for that.
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Pinned the first dose into my subject today. The reaction is very similar to the SS31 reaction. Turns warm, itchy and red almost immediately. the area spreads out left to right on my stomach perhaps 1 to 1.5 inches. and then up and down half an inch or so. But within 1 hour its gone. AI says its most likely not even a histamine reaction but just a local cell reaction to the peptide itself.
But this was just the first pin which was a baby dose (0.5mg) at 10mg/3ml dilution.
Pinned the first dose into my subject today. The reaction is very similar to the SS31 reaction. Turns warm, itchy and red almost immediately. the area spreads out left to right on my stomach perhaps 1 to 1.5 inches. and then up and down half an inch or so. But within 1 hour its gone. AI says its most likely not even a histamine reaction but just a local cell reaction to the peptide itself.
But this was just the first pin which was a baby dose (0.5mg) at 10mg/3ml dilution.
Try changing to the upper glute or hip area. The stomach can be more of a sensitive spot for some people. Also, let it sit out for about 20-25 minutes before pinning. Both of those things have helped in my household.
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@mrjoshua44 I was under impression that adding peptides to saline solutions may be harmful to the molecules, also isn't it irritable for nasal tissue. I am planning to make a nasal solution myself so I bought USP sterile water for that.
@vpeptides First, saline is specifically preferred when running nasal spray as it matches the body's natural osmolarity, making it ideal for maintaining physiological balance. Second, most water-soluble peptides work well with BAC 0.9% Sodium Chloride; GLP-1 agonists (semaglutide, tirzepatide, retatrutide), Growth hormone secretagogues (CJC-1295, ipamorelin, sermorelin), Healing peptides (BPC-157, TB-500), Cognitive peptides (Selank, Semax).
Critical Exceptions
Copper-Containing Peptides GHK-Cu and AHK-Cu, NAD+ and the following require more of an acidic dissolution; IGF-1 LR3, IGF-1 DES, MGF, PEG-MGF, Follistatin, and Melanotan I.For my own research purposes, I've only used it for MOTS-c and SS-31 to reduce injection site reactions.
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My experience with Mots C.
I starting in the beginning of the year and maybe 1 month in all good and dandy.
This was Subq
Then some itching started.
Then some welts.
Then some allergic reaction with a welt that took 3 weeks to disappear.
I took some time off and i came back 1mg IM in the ventral glute. No reaction, then up the dose to 2 then 3mg 3x a week. Ive been like this 2 months and i dont even feel it with 0 reactions.
I would test 1mg IM then gradually titrate up to your desired dose. I could do 1mg daily but i use that area for L-cartinine and Test so i do the Motsc 3x a week
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