Skip to content
  • Categories
  • Recent
  • Tags
  • Popular
  • World
  • Users
  • Groups
Skins
  • Light
  • Brite
  • Cerulean
  • Cosmo
  • Flatly
  • Journal
  • Litera
  • Lumen
  • Lux
  • Materia
  • Minty
  • Morph
  • Pulse
  • Sandstone
  • Simplex
  • Sketchy
  • Spacelab
  • United
  • Yeti
  • Zephyr
  • Dark
  • Cyborg
  • Darkly
  • Quartz
  • Slate
  • Solar
  • Superhero
  • Vapor

  • Default (Zephyr)
  • No Skin
Collapse
Peptide Critic Community

Peptide Critic Community

  1. Randy the Rats Research Forum
  2. Supplies, Mixing & Storage
  3. Really need help-If Peptide Vendors Can’t Be Trusted for Sterility, Why Trust the Filters?
Prize
Red, White & Blue V2 Pens
Ends in
8161 entries · 1000 participants
Enter →

Really need help-If Peptide Vendors Can’t Be Trusted for Sterility, Why Trust the Filters?

Scheduled Pinned Locked Moved Supplies, Mixing & Storage
filtersreconstitutionmixingbeginner-question
13 Posts 7 Posters 856 Views
  • Oldest to Newest
  • Newest to Oldest
  • Most Votes
Reply
  • Reply as topic
Log in to reply
This topic has been deleted. Only users with topic management privileges can see it.
  • D Offline
    D Offline
    danielgegic
    wrote on last edited by
    #1

    I am brand new to peptide world. This is my thinking really looking for guidance here...

    I’ve been watching channels like Peptide Critic and Peptide Test, where they filter peptides because the assumption is that some vendors may not be fully trustworthy regarding sterility. But I’m struggling to understand why the filters, used in that process are automatically considered more trustworthy than the original vial itself.

    Most of those filters and supplies are also sold as “research use only,” just like many of the peptides. If the concern is that a peptide vendor may not truly be sterile despite claiming sterility or providing a COA, then why should we assume that an independently purchased filter or empty vial is genuinely sterile either?

    It also seems like filtering introduces additional opportunities for contamination. Instead of leaving the product sealed in its original vial, the process involves multiple extra handling steps: reconstituting, drawing into a syringe, pushing through a filter, transferring into another vial, and exposing more surfaces and components along the way. Every additional step appears to create another possible contamination point.

    So while I understand the argument that filtration could theoretically reduce certain risks, I don’t fully understand how it meaningfully improves safety unless the filters, receiving vials, and entire transfer process are themselves held to a higher and verifiable sterility standard. Otherwise, it feels like the process may simply be shifting the trust problem from one “research-use” product to another while also increasing handling and exposure.

    Am I wrong in my thinking? If so, please explain why. Or if you have a trusted brand of filters from a major company (like Hospira BAC water) please let me know.

    Thanks everyone!

    1 Reply Last reply
    1
    • RandyR Offline
      RandyR Offline
      Randy
      wrote on last edited by
      #2

      Most of the filters are radiation sterilized. Follow proper procedure and you wont get any contamination.

      "If it doesnt come in a needle. It doesn't work"

      1 Reply Last reply
      3
      • T Offline
        T Offline
        theckman80
        wrote on last edited by
        #3

        TL;DR: Find vendors/manufacturers for BAC water and filters that are certified in the US to meet Current Good Manufacturing Practices (cGMP)/ISO 9001/CE etc. If you do that, you have 3rd party auditors looking over their shoulders for you.

        Because you're buying gray market, it's hard to prove things like cGMP because there is less regulatory burden. Its also why everything is so much cheaper. When you buy filters from a place like Biologix USA, you are buying from a firm that is ISO 9001 certified and audited. That means they have policies, procedures, records, and practices that can be verified through a 3rd party audit firm. If you look on Biologix's website, you'll see, "Our R&D focus is on advancement of core products. Our clean rooms are standard class 100,000 and compliant with GMP standards. All clean rooms are ISO 9001, CE registered and follow the strict CDC guidelines for purity and efficiency." While those things could be just words on a page, you can actually verify CE registration and ISO 9001 certification. If you were to buy a 10mg vial of Lily Trazepetide it would be $449.00 out of pocket with the current discount , full price being $1,087.00. For that price, purchasing a grey market 10 pack, going in on a group test, and purchasing Pfizer's BAC water doesn't sound half bad. Now, you might get it from your insurance for less than 449 for 10mg, but not everyone can.

        image.png

        1 Reply Last reply
        2
        • E Online
          E Online
          Eleanor
          wrote on last edited by Eleanor
          #4

          Where can I find vent needles for a decent price? I thought of using just regular 1ml syringe, pulling out plunger and seeing if that worked. No expense burning those Comfort syringes. Anybody w/opinion?

          C 1 Reply Last reply
          -1
          • D Offline
            D Offline
            danielgegic
            wrote on last edited by
            #5

            Thank you!

            1 Reply Last reply
            1
            • E Eleanor

              Where can I find vent needles for a decent price? I thought of using just regular 1ml syringe, pulling out plunger and seeing if that worked. No expense burning those Comfort syringes. Anybody w/opinion?

              C Offline
              C Offline
              Chuxpeps
              wrote on last edited by
              #6

              @Eleanor, I use a 31-ga insulin syringe with the plunger removed; never had an issue. Sometimes I use a luer-lock needle, but I don't have many of them around anymore.

              E 1 Reply Last reply
              1
              • C Chuxpeps

                @Eleanor, I use a 31-ga insulin syringe with the plunger removed; never had an issue. Sometimes I use a luer-lock needle, but I don't have many of them around anymore.

                E Online
                E Online
                Eleanor
                wrote on last edited by
                #7

                @Chuxpeps Thank you so much! I have plenty of the 1ml and the physics made sense, so I don't want to buy anything I don't have to buy. Muchas gracias!

                1 Reply Last reply
                0
                • vpeptidesV Offline
                  vpeptidesV Offline
                  vpeptides
                  wrote on last edited by
                  #8

                  Biologix USA sells PES fillers. I learned that Hydrophilic PVDF filters are better because they stop less of the peptide material than PES.

                  1 Reply Last reply
                  1
                  • T Offline
                    T Offline
                    theckman80
                    wrote on last edited by
                    #9

                    @Eleanor i just use regular lurelock 32ga needles from Amazon. They are super cheap for a box of 100. I bend the vent needle by 20 degrees so the plastic part is out of the way while I fill my pen vial.

                    1 Reply Last reply
                    1
                    • E Online
                      E Online
                      Eleanor
                      wrote on last edited by
                      #10

                      @vpeptides Either that, or as Our Host does, push some extra bac into it to clear it.
                      @theckman80 That's a good idea too. Either way I go, I'm going to have to bend the needle.

                      1 Reply Last reply
                      2
                      • T Offline
                        T Offline
                        theckman80
                        wrote on last edited by
                        #11

                        You can also just add a small air bubble at the topmof you syringe full of peptide and push the last of the peptide through with air.

                        1 Reply Last reply
                        0
                        • J Offline
                          J Offline
                          jamiegallien
                          wrote on last edited by
                          #12

                          In the end your needed safety level is a personal thing. You can go down the rabbit hole and find possibilities for problems everywhere. You may fall at the level where gray peps just don't make sense to you. I have friend that doesn't test anything and just pins. I am more in the middle. I filter, have tests done on batches, and do what I can do minimize the chances, but know the risks.

                          1 Reply Last reply
                          1
                          • J Offline
                            J Offline
                            jamiegallien
                            wrote on last edited by
                            #13

                            Also, there are sources for the filters that can be confirmed legit, you just won't find them on Amazon.

                            1 Reply Last reply
                            1

                            Hello! It looks like you're interested in this conversation, but you don't have an account yet.

                            Getting fed up of having to scroll through the same posts each visit? When you register for an account, you'll always come back to exactly where you were before, and choose to be notified of new replies (either via email, or push notification). You'll also be able to save bookmarks and upvote posts to show your appreciation to other community members.

                            With your input, this post could be even better 💗

                            Register Login
                            Reply
                            • Reply as topic
                            Log in to reply
                            • Oldest to Newest
                            • Newest to Oldest
                            • Most Votes


                            • Login

                            • Login or register to search.
                            • First post
                              Last post
                            0
                            • Categories
                            • Recent
                            • Tags
                            • Popular
                            • World
                            • Users
                            • Groups