Nexaph 3rd Party Testing
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I’m a noob as well but the way I understand it is the Nexaph telegram group is used so that researchers donate a sample from their own kits and Nexaph pays for the test. My understanding is that this gives researchers a reasonable assumption that the company didn’t “hand pick” certain samples they knew would look good on a COA. Thus making it more of a “random” and “fair” test. They only test for mass content and purity. So the benefit of a third party group test in my eyes would be that researchers could do more tests, (sterility, endotoxins, heavy metals) and a plus would be that you could get more samples to average out mass content. Being new to a lot of this. I will do the third party group testing. It just makes me feel more warmer and fuzzier inside.
@WesEqualshXc It also reduces (but does not eliminate) the possibility that Nexaph is shipping multiple batches under a single batches testing, because effectively the vials being tested are randomized across all the vials they send out under a given batch ID. Its all a statistical game, but the probabilities are better with Nexaph than with many others.
I am generally a fan of Nexaph, and use them for many many things... but one thing I'm not a fan of is certain compounds (like 5-amino-1mq) Janoshik does not offer purity tests for (only mass tests) and since Nexaph exclusively uses Janoshik (for reasons I broadly agree with) I don't personally trust those tests. So I run my own. And what I can say is that at least for 5-amino-1mq not only do the third party tests I've commissioned directly via Analytic Formulations come back at excellent purity and acceptable (to me) mass (a bit overfilled, but manageable) but also are clean on sterility, heavy metals, and endotoxins.
Again, its a statistical game, so take that simply as more data points to add into the risk tolerance computation
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This is the endo and mass/purity from the illustrious JEEP/BARN T30 batch from january. These results woke a lot of people up.
https://verify.janoshik.com/tests/136052-Sterility2_A749RCAF7WEC
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@Randy What happens to the kits once these kinds of results are released? This is a little scary!
@kmckinley nothing.
They claimed they we're taking steps and found the source blah blah blah "excipient testing". I'm aware, a few people asked for refunds and got them and there are others that are still filtering that batch.
There was a issue with purity on a motsc batch and they did store credit. I had a bottle where the crimp was messed up and they gave me a refund for that.
I do believe they do their best and they're trying to do the right thing but just realize their batches are 30,000 bottles and you're getting results for three of those bottles.
Still less shady than Jenny on WhatsApp.
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@kmckinley nothing.
They claimed they we're taking steps and found the source blah blah blah "excipient testing". I'm aware, a few people asked for refunds and got them and there are others that are still filtering that batch.
There was a issue with purity on a motsc batch and they did store credit. I had a bottle where the crimp was messed up and they gave me a refund for that.
I do believe they do their best and they're trying to do the right thing but just realize their batches are 30,000 bottles and you're getting results for three of those bottles.
Still less shady than Jenny on WhatsApp.
@Randy Yikes! So, I am assuming they continue to sell said batches on the site? It is good to know they refunded some and I guess just like anything else we buy that breaks but I would hope they would have to "recall" or remove them as a safety precaution.
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@kmckinley nothing.
They claimed they we're taking steps and found the source blah blah blah "excipient testing". I'm aware, a few people asked for refunds and got them and there are others that are still filtering that batch.
There was a issue with purity on a motsc batch and they did store credit. I had a bottle where the crimp was messed up and they gave me a refund for that.
I do believe they do their best and they're trying to do the right thing but just realize their batches are 30,000 bottles and you're getting results for three of those bottles.
Still less shady than Jenny on WhatsApp.
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@Randy
Although this is true, Jenny on WhatsApp is much hotter…. I am sure that is her real picture!!!@Commander its definitely her. Not some overweight middle aged man named Huang.
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@Randy Yikes! So, I am assuming they continue to sell said batches on the site? It is good to know they refunded some and I guess just like anything else we buy that breaks but I would hope they would have to "recall" or remove them as a safety precaution.
@kmckinley no. I didnt say that. These sell out long before the sterility results from group tests come back. T30 is usually a presale and sells out at that point. That was the one failure we've seen in many hundreds of batches.
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@kmckinley no. I didnt say that. These sell out long before the sterility results from group tests come back. T30 is usually a presale and sells out at that point. That was the one failure we've seen in many hundreds of batches.
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If anyone knows it would be interesting to get an answer. If purity is over 99pct most are over 99.5pct is it even statistically possible to have enough endotoxins or heavy metals to fail? The Jano guy straight up said it’s a waste of time. (I am paraphrasing) the Nexaph people apparently feel this way. Same for sterility. Most people believe the difference between 99.5 and 100 or whatever is just moisture from the manufacturing process or degradation. We see this is the random testing on telegram they always pass in the Nexaph threads.
@Stevepep I just watched a video on YT, from "PepTok" (Rory from Crush) and he interviews Trustpoint Analytical. Starting at about 7:30 he has the best explanation on the differences Ive heard yet. This, combined with several other comments about LPS from other well know podcasters, specifically Huberman, and Im starting to have a better understanding.
Thought I would mention it here. Maybe it helps. I am not linking it here because my dumbass hasn't read all of the forum rules and I dont want to get in trouble. -
@ResearchCat the endotoxin testing is an interesting topic. According to the Jano guy with purity levels well over 90 pct it’s impossible for the toxins to be high enough not to pass so it’s unnecessary testing.
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@ResearchCat the endotoxin testing is an interesting topic. According to the Jano guy with purity levels well over 90 pct it’s impossible for the toxins to be high enough not to pass so it’s unnecessary testing.
@ResearchCat the endotoxin testing is an interesting topic. According to the Jano guy with purity levels well over 90 pct it’s impossible for the toxins to be high enough not to pass so it’s unnecessary testing.
This is not true. Peter said endotoxin failures are rare, but not zero. He gave percentage failures in an interview. Endotoxins and purity have no correlation. A 99% pure product can still have high enough endotoxins.
The only nuance is endotoxin effect depends on research subject's weight and per dose endotoxin exposure. There's some limit you can find online.
Recently when JEEP Tirzepatide failed endo results, that limit exceeded despite high purity.
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This is the endo and mass/purity from the illustrious JEEP/BARN T30 batch from january. These results woke a lot of people up.
https://verify.janoshik.com/tests/136052-Sterility2_A749RCAF7WEC
This is the endo and mass/purity from the illustrious JEEP/BARN T30 batch from january. These results woke a lot of people up.
https://verify.janoshik.com/tests/136052-Sterility2_A749RCAF7WEC
THIS!
Boy this is a long thread. I didn't realize but this is exactly what I was referring to in my previous reply. Endotoxins and purity are not related.
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@ResearchCat the endotoxin testing is an interesting topic. According to the Jano guy with purity levels well over 90 pct it’s impossible for the toxins to be high enough not to pass so it’s unnecessary testing.
This is not true. Peter said endotoxin failures are rare, but not zero. He gave percentage failures in an interview. Endotoxins and purity have no correlation. A 99% pure product can still have high enough endotoxins.
The only nuance is endotoxin effect depends on research subject's weight and per dose endotoxin exposure. There's some limit you can find online.
Recently when JEEP Tirzepatide failed endo results, that limit exceeded despite high purity.
@pep_researcher finally someone says it. Thank you!
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@Stevepep I just watched a video on YT, from "PepTok" (Rory from Crush) and he interviews Trustpoint Analytical. Starting at about 7:30 he has the best explanation on the differences Ive heard yet. This, combined with several other comments about LPS from other well know podcasters, specifically Huberman, and Im starting to have a better understanding.
Thought I would mention it here. Maybe it helps. I am not linking it here because my dumbass hasn't read all of the forum rules and I dont want to get in trouble.@JtCjEfF Good interview - thanks for letting us know!
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This is the endo and mass/purity from the illustrious JEEP/BARN T30 batch from january. These results woke a lot of people up.
https://verify.janoshik.com/tests/136052-Sterility2_A749RCAF7WEC
THIS!
Boy this is a long thread. I didn't realize but this is exactly what I was referring to in my previous reply. Endotoxins and purity are not related.
@pep_researcher I saw this @randy posted it. That put that to bed. It just shows you how much bad information is out there. Which leads to sterility. Wouldn't filtering remove any bacteria or fungi? Isn't that the purpose? According to YouTube University, it does. It also says the bacteria, fungi, and yeast can form during storage. Meaning, during the time it was tested, it will pass, but after storage (some of us have years of peptides), it can fail as the peptide degrades. Another reason not to hoard, I guess.
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@ResearchCat the endotoxin testing is an interesting topic. According to the Jano guy with purity levels well over 90 pct it’s impossible for the toxins to be high enough not to pass so it’s unnecessary testing.
This is not true. Peter said endotoxin failures are rare, but not zero. He gave percentage failures in an interview. Endotoxins and purity have no correlation. A 99% pure product can still have high enough endotoxins.
The only nuance is endotoxin effect depends on research subject's weight and per dose endotoxin exposure. There's some limit you can find online.
Recently when JEEP Tirzepatide failed endo results, that limit exceeded despite high purity.
@pep_researcher Interesting, listened to the Trustpoint and then the Jano guy on Peptock. It was great; it appears endotoxin is worthless if you test for sterility. He said it's never happened where you have high endotoxins and it passes sterility. It's also extremely rare to have endotoxins at all, but like 5% don't pass sterility. Testing for heavy metals is totally useless. So dumb me, I have been doing endotoxin and HPLC testing. I should be doing HPLC and sterility. All these test groups and our own personal testing tell the story. Endoxins are extremely rare. I am aware of only one failure, and it was Jeep.
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This is the endo and mass/purity from the illustrious JEEP/BARN T30 batch from january. These results woke a lot of people up.
https://verify.janoshik.com/tests/136052-Sterility2_A749RCAF7WEC
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