Med sensitive RS seeking advice on ss-31 protocol

[emkay]

My RS is a generally medication sensitive type, children's doses for OTC meds, tirz dosing has been 1.25-1.5 mg a week split dose (.6-.7 mg 3.5 days apart) and cannot go higher due to side effects. RS also has a very long history of caloric restriction (276 lbs to 135 lbs) and extreme lethargy and wants to try a cycle of ss-31.

I'm seeing beginner protocols starting around 5 mg, and wondering if 2.5 mg for this RS is reasonable, if she should start lower, or if it's unlikely to even help lower than 5 mg. Not stacking with Mots-c at this time to try to isolate any issues/benefits that may occur.

Any other med sensitive types have experience with this one?

[Eleanor]

Great question. I just got SS-31 and am sensitive.
Bumping this to the top.

[SwollStreetBets]

@gym.rat Question for you, could I use something like a pH strip to check if my NAD+ is buffered or not? If so, what ranges should I be looking for and if it's not buffered, would adding something like sodium bicarbonate be advisable?

[Eleanor]

@gym.rat Is your rat continuing past 8 weeks on SS-31? I want to start shortly and with lowest dose, reducing NAD+ buf to every other day at 25 instead of 40 daily. No MOTSC for a while. Love my NAD+buf and never had a sting from it; I dilute it pretty well.

@swollstreetbets On special, 1000mg, NAD+buffered, $55 single vial or kits lower, S1research.net
Got the SS-31 there too. They also have MOTSC but haven't done price comparisons.

[Eleanor]

@gym.rat Thanks much. I'm aiming for 8 wks, but if part of vial is left over, it's going until empty. Will give it a break then start MOTSC. (Meant continue NAD+ full load as before)

[EXTROPIAN]

Before you do SS-31. I would advice MOTSC and NAD as a base line to see how you respond. If you still feel weak.Then I would try the SS-31 along with the two. Or do all of them like I did just in case. That is if you dont have the means for blood work with someone who knows how to read it. You will definitely feel MOTSC if it isna good source. *This cute Asian girl talked into buying a kit and it was a little weak like my trust.

[Eleanor]

@gym.rat I did read the full write up but have a question regarding sequence. Am posting a separate thread on this and appreciate yours and everyone's knowledge on this.