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New tesamorelin user

Scheduled Pinned Locked Moved Peptide Discussion
23 Posts 15 Posters 1.4k Views
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  • S Offline
    S Offline
    Shaqdiesel
    wrote last edited by
    #12

    Tes 1mg Ipa 300mcg 5/2 at night fasted (3-4 hours). Just finished 16 weeks, going for 18 weeks. I did blood work Friday, waiting on results. I do have a baseline as well so I can see how far it pushed me over the 16 weeks. I will take a couple months off. I have enough for another 16 weeks at the same dosing. I plan to start around Dec 1st ish. This is Nexaph stock(10/3 blend).

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    • S SkepticJen

      @EXTROPIAN great thread - thanks all. I have some tesa coming to start tomorrow night, and I was thinking 500 mcg before bed, 5/2. I only bought enough for one month because I figure that'll give me time to decide if this is for me. And it gave me a reason to try the new pen 🙂

      N Offline
      N Offline
      Neil McCauley
      wrote last edited by Neil McCauley
      #13

      @SkepticJen said:

      @EXTROPIAN great thread - thanks all. I have some tesa coming to start tomorrow night, and I was thinking 500 mcg before bed, 5/2. I only bought enough for one month because I figure that'll give me time to decide if this is for me. And it gave me a reason to try the new pen 🙂

      Good luck. Definitely lower dose to start is a great idea. I and many others have seen results at 1mg, so I think 500mcg especially combined with Ipamorelin you will likely have positive results.

      Remember those Tesa study participants on 2mg not only were HIV+, they didn't use Ipamorelin, and I'm almost positive they were not even bothering to pin around fasted times which we know drastically increases the effectiveness.

      To top all that off, I believe they were specifically chosen as having excessive visceral fat (lipodystrophy) which blunts GHRH response, so it's likely the 2mg standard dose you see many start with/what the study used is actually a very high end dosage that was needed specifically for them given their preexisting health conditions.

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      • S SkepticJen

        @EXTROPIAN great thread - thanks all. I have some tesa coming to start tomorrow night, and I was thinking 500 mcg before bed, 5/2. I only bought enough for one month because I figure that'll give me time to decide if this is for me. And it gave me a reason to try the new pen 🙂

        ResearchCatR Offline
        ResearchCatR Offline
        ResearchCat
        wrote last edited by
        #14

        @SkepticJen While I don’t have a problem with you running a one month test to see how you tolerate Tesa, be aware that like sermorelin, you likely won’t see tangible results in only one month. Tesa really needs 3-4 months. Sermorelin even longer. One of the reasons people rave about CJC/Ipa is that you often see results starting in 4-6 weeks and two month cycles show meaningful improvements.

        My last run of tesa was two months - i stopped because 2mg was too much, and the biometrics and mirror didn’t show much difference. I immediately ran two months of CJC/Ipa and saw definitely improvement in definition and marginal reduction in visceral fat.

        Yeah, well, I’m just here for the research, man. - The Dude

        If I haven’t liked your post, no offense. I have exceeded my daily allowance.

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        • B Offline
          B Offline
          brandenscheidecker
          wrote last edited by
          #15

          Go big or go home! 2mg tesa/.300 ipa 7 days a week! 6 months! melt that fat away!

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          • EXTROPIANE Offline
            EXTROPIANE Offline
            EXTROPIAN
            wrote last edited by EXTROPIAN
            #16

            Or be patient if you want to improve your health and good body composition. If you want to get shredded or close to it. Just listen to some of these boys. But common guys, what would happen if you boost your testosterone? lt can be micro dosed as well for its metabolic benefits and you will look good.

            2M

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            • M Online
              M Online
              MikeMiranda
              wrote last edited by
              #17

              During testing Egrifta/Tesa was tested at 26weeks

              https://www.ncbi.nlm.nih.gov/books/NBK539127/

              N 1 Reply Last reply
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              • M MikeMiranda

                During testing Egrifta/Tesa was tested at 26weeks

                https://www.ncbi.nlm.nih.gov/books/NBK539127/

                N Offline
                N Offline
                Neil McCauley
                wrote last edited by Neil McCauley
                #18

                @MikeMiranda said:

                During testing Egrifta/Tesa was tested at 26weeks

                https://www.ncbi.nlm.nih.gov/books/NBK539127/

                What is kinda crazy is that the study participants didn't even pin fasted. Who knows how much bettter the results would have been had they made that change in the protocol. Also makes you wonder if that was even a known thing among the researchers who developed the study. You'd think they would have known that?

                Hopefully Big Pharma is paying attention to the discoveries going on in the RUO communities.

                D 1 Reply Last reply
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                • N Neil McCauley

                  @MikeMiranda said:

                  During testing Egrifta/Tesa was tested at 26weeks

                  https://www.ncbi.nlm.nih.gov/books/NBK539127/

                  What is kinda crazy is that the study participants didn't even pin fasted. Who knows how much bettter the results would have been had they made that change in the protocol. Also makes you wonder if that was even a known thing among the researchers who developed the study. You'd think they would have known that?

                  Hopefully Big Pharma is paying attention to the discoveries going on in the RUO communities.

                  D Offline
                  D Offline
                  derekg1
                  wrote last edited by
                  #19

                  @Neil-McCauley said:

                  @MikeMiranda said:

                  During testing Egrifta/Tesa was tested at 26weeks

                  https://www.ncbi.nlm.nih.gov/books/NBK539127/

                  What is kinda crazy is that the study participants didn't even pin fasted. Who knows how much bettter the results would have been had they made that change in the protocol. Also makes you wonder if that was even a known thing among the researchers who developed the study. You'd think they would have known that?

                  Hopefully Big Pharma is paying attention to the discoveries going on in the RUO communities.

                  Makes me wonder if pinning fasted isn't as big as big of a deal as we make it or the patients were so bad off on health pinning fasted or not had little impact on their response.

                  N 1 Reply Last reply
                  0
                  • D derekg1

                    @Neil-McCauley said:

                    @MikeMiranda said:

                    During testing Egrifta/Tesa was tested at 26weeks

                    https://www.ncbi.nlm.nih.gov/books/NBK539127/

                    What is kinda crazy is that the study participants didn't even pin fasted. Who knows how much bettter the results would have been had they made that change in the protocol. Also makes you wonder if that was even a known thing among the researchers who developed the study. You'd think they would have known that?

                    Hopefully Big Pharma is paying attention to the discoveries going on in the RUO communities.

                    Makes me wonder if pinning fasted isn't as big as big of a deal as we make it or the patients were so bad off on health pinning fasted or not had little impact on their response.

                    N Offline
                    N Offline
                    Neil McCauley
                    wrote last edited by Neil McCauley
                    #20

                    @derekg1 said:

                    @Neil-McCauley said:

                    @MikeMiranda said:

                    During testing Egrifta/Tesa was tested at 26weeks

                    https://www.ncbi.nlm.nih.gov/books/NBK539127/

                    What is kinda crazy is that the study participants didn't even pin fasted. Who knows how much bettter the results would have been had they made that change in the protocol. Also makes you wonder if that was even a known thing among the researchers who developed the study. You'd think they would have known that?

                    Hopefully Big Pharma is paying attention to the discoveries going on in the RUO communities.

                    Makes me wonder if pinning fasted isn't as big as big of a deal as we make it or the patients were so bad off on health pinning fasted or not had little impact on their response.

                    I think its all of the above. Pinning fasted helps, but perhaps its only say 25% more effective (total guess there, have no idea) and the patients had such little igf-1 signaling going on for years that even something as mild as a single peptide secretagogue, taken without being fasted so perhaps with blunted effectiveness, still moved the needle quite a bit in a positive direction.

                    It does also lean into my hypothesis that 2mg is actually a very high dosage, and that was needed for all the reasons mentioned above in order to get the most favorable outcomes from the participants.

                    It really all points in a positive direction for Tesamorelin and its effectiveness. The study certainly wasn't designed for optimal outcomes (reasons I noted above) and was actually quite handicapped, the participants were far from healthy subjects to begin with (quite the opposite actually) and despite all that the outcomes were pretty favorable.

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                    • M Online
                      M Online
                      MikeMiranda
                      wrote last edited by
                      #21

                      In this document the recommended dosage ws 1.28-1.4 in different variations of egrifta

                      https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/022505s020lbl.pdf

                      N 1 Reply Last reply
                      1
                      • EXTROPIANE Offline
                        EXTROPIANE Offline
                        EXTROPIAN
                        wrote last edited by
                        #22

                        Has anyone or know anyone who have researched CJC-1295 with DAC (Drug Affinity Complex)?

                        2M

                        1 Reply Last reply
                        0
                        • M MikeMiranda

                          In this document the recommended dosage ws 1.28-1.4 in different variations of egrifta

                          https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/022505s020lbl.pdf

                          N Offline
                          N Offline
                          Neil McCauley
                          wrote last edited by
                          #23

                          @MikeMiranda said:

                          In this document the recommended dosage ws 1.28-1.4 in different variations of egrifta

                          https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/022505s020lbl.pdf

                          Mean age was 48 as well, even older than I would have assumed.

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