A PRELIMINARY RETA EXIT.
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@Mydogdaryl423 I am in between. I am content where I am. Up to this point I have no need to push but just maintain a healthy life. I am 55yo with a young wife, infant and a toddler. More about longevity then anything else. Never had an elite physic but have maintained above average. Til this day I still chase extropy. And peptides are fascinating. I just need a break.
@Mydogdaryl423 I am in between. I am content where I am. Up to this point I have no need to push but just maintain a healthy life. I am 55yo with a young wife, infant and a toddler. More about longevity then anything else. Never had an elite physic but have maintained above average. Til this day I still chase extropy. And peptides are fascinating. I just need a break.
Shit man. You need all the energy you can get. Young wife, infant and toddler. Bless you. Im trying to hit that above average myself. I absolutely get it and understand needing a break.
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@Mydogdaryl423 I am in between. I am content where I am. Up to this point I have no need to push but just maintain a healthy life. I am 55yo with a young wife, infant and a toddler. More about longevity then anything else. Never had an elite physic but have maintained above average. Til this day I still chase extropy. And peptides are fascinating. I just need a break.
Shit man. You need all the energy you can get. Young wife, infant and toddler. Bless you. Im trying to hit that above average myself. I absolutely get it and understand needing a break.
@Mydogdaryl423 Hey I tell you. The mitochondria cycle helped significantly and repaired a knee. lol
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@Mydogdaryl423 On your off cycles. What tips do you have?
@Mydogdaryl423 On your off cycles. What tips do you have?
Use it to your advantage. Use the extra calories. Coincide it with training. Maybe switch up your training to challenge your body. If your a high rep guy go low rep and heavier or vice versa. Switching up what I ate was key. I was eating such small portions. Learning to increase those portions and make higher volume meals was a great skill to learn. Watch the scale. You want it to go up but very small. You know you can cut later.
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@Mydogdaryl423 On your off cycles. What tips do you have?
Use it to your advantage. Use the extra calories. Coincide it with training. Maybe switch up your training to challenge your body. If your a high rep guy go low rep and heavier or vice versa. Switching up what I ate was key. I was eating such small portions. Learning to increase those portions and make higher volume meals was a great skill to learn. Watch the scale. You want it to go up but very small. You know you can cut later.
@Mydogdaryl423 Already noted. I'll drop my experience here weekly. I am doing more reps less heavy on shoulder and chest due I have a shoulder replacement. It has not giving me any trouble until I started gaining mass on the shoulders. It started to press against the implant. But I am working around it.
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So Glow did help? My mother has lost quite a bit of weight and is concerned over the skin.
So Glow did help? My mother has lost quite a bit of weight and is concerned over the skin.
It obviously could be anecdotel but I had much more loose skin before glow. I absolutely see the difference. I would say the most important thing she could do is manage the weight loss. Dont lose too much too fast.
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@Mydogdaryl423 Already noted. I'll drop my experience here weekly. I am doing more reps less heavy on shoulder and chest due I have a shoulder replacement. It has not giving me any trouble until I started gaining mass on the shoulders. It started to press against the implant. But I am working around it.
@Mydogdaryl423 Already noted. I'll drop my experience here weekly.
Thats awesome. Ill do the same.
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So Glow did help? My mother has lost quite a bit of weight and is concerned over the skin.
It obviously could be anecdotel but I had much more loose skin before glow. I absolutely see the difference. I would say the most important thing she could do is manage the weight loss. Dont lose too much too fast.
@Mydogdaryl423 Yes that's what I told her. She was a triz but not covered anymore and got expensive. She still has some left. She started reta a month ago and loves it. She is eating well and losing slowly but losing. The idea is losing slowly and allowing the skin to adapt. I was considering sending her some
GHK-CU but I dont know if she can pin that much. Guess it runs in the family. I ammalso sending her some bpc and tb for them mechanical aches. -
Here is currently and the before. Crazy seeing this.
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Here is currently and the before. Crazy seeing this.
@Mydogdaryl423 Wow, amazing!! That unreal ..... great work!
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@Mydogdaryl423 great job!
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Here is currently and the before. Crazy seeing this.
@Mydogdaryl423 Great Job Buddy!
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Today is the day. Instead of 1mg I went for .5mg, the tapering starts. I was talking to a friend and she said after a couple of months of 1-1.5mg she was off for over a month and didn't have a hunger attack. She has been getting off the slop before reta, as I. If there is a rebound I want to feel it. Bring it!
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Just a heads up… many, many people find that GLPs are less effective or flat out don’t work at all after having been on them previously. The idea of cycling GLPs is so misguided.
@Mydogdaryl423 Could you be specific as to what exactly "these" are that you say you have cycled "multiple times?" Thanks...
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Today is the day. Instead of 1mg I went for .5mg, the tapering starts. I was talking to a friend and she said after a couple of months of 1-1.5mg she was off for over a month and didn't have a hunger attack. She has been getting off the slop before reta, as I. If there is a rebound I want to feel it. Bring it!
@EXTROPIAN Takes more than a month to completely clear from your system.
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@EXTROPIAN Takes more than a month to completely clear from your system.
@Elysium2132 Yep. It takes 4.5 half lives of a drug to reach steady state or to be eliminated from your system, assuming first order (linear) kinetics. This puts reta at 27 days for elimination with a half life of 144 hours.
Half-Life Comparison
• Tirzepatide: Approximately 5 days (120 hours). It is a dual GLP-1 and GIP receptor agonist.
• Retatrutide: Approximately 6 days (144 hours). It is a triple GLP-1, GIP, and glucagon receptor agonist.
• Survodutide: Approximately 4.5 to 6 days (109 to 144 hours). It is a dual GLP-1 and glucagon receptor agonist.
• Mazdutide: Approximately 7 to 9 days (ranging up to ~8 days in clinical evaluations). It is a dual GLP-1 and glucagon receptor agonist. -
@EXTROPIAN Takes more than a month to completely clear from your system.
@Elysium2132 OK let's do some numbers. If Retatrutide was given a half life of 6 days. That means by the 6 day it will be 50% in concentration in the body. So does this mean the other 50% will be cleared by next week? Reta was design to shield itself from an enzyme (dpp-4) that specifically targets glp, gip. Without the shield glp and gip will be eliminated in minutes. And they also added this fatty acid chain to the molecule to bind to albumin. So the question is. If the biological half-life of albumin in the human body is approximately 18 to 21 days. This means half of the protein is broken down and recycled every three weeks. Note that if retatrutide was left undisturbed it will continue to do what it does indefinitely bindingnto receptor cells for a few minute and on to the next one, like a pimp. There are still other enzyme (proteases and peptidases) circulating in the blood system and tissues that breaks it down before itnis filtered through your liver. So what is the half life 6 days or 18-21 days? If it is 18 to 21 half life because it is attached and circulating with its buddy albumin. Then why am I pinning every week? If it takes over a month to completely clear out of my system. Where is it in the body? It just doesn't add up. But this I can confirm. From 2mg to .5mg on the first week of tapering. Food is starting to taste pretty good. The supressed dopamine, endorphines are starting to fire up, serotonin is still holding its ground.
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