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Nexaph testing

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  • M mikebricker

    One thing about Nexaph I don’t understand is the partial testing on some items of the same peptide.
    Look at Reta. 10mg only purity/potency/ID. But on the 12mg a full test. Why is that? The suspicious part of me thinks maybe the 10mg had higher than normal Endo?
    I like Nexaph and they have become my go to. But inquiring minds want to know…?

    BeeKindB Offline
    BeeKindB Offline
    BeeKind
    wrote last edited by
    #32

    @mikebricker they are switching over to more full testing, they are probably trying to get rid of what was previously tested first before transitioning each item over.

    Just someone with a fridge full of research and a browser history that would concern my doctor.

    1 Reply Last reply
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    • M mikebricker

      One thing about Nexaph I don’t understand is the partial testing on some items of the same peptide.
      Look at Reta. 10mg only purity/potency/ID. But on the 12mg a full test. Why is that? The suspicious part of me thinks maybe the 10mg had higher than normal Endo?
      I like Nexaph and they have become my go to. But inquiring minds want to know…?

      S Online
      S Online
      Stevepep
      wrote last edited by
      #33

      @mikebricker just check the third party testing it will be there. Like others have said on the older stuff they paid for third party endo, sterility and heavy metal testing people got confused so they swapped it and now do the full panel testing and pay for third party testing partial panel.

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      • S Stevepep

        @mikebricker just check the third party testing it will be there. Like others have said on the older stuff they paid for third party endo, sterility and heavy metal testing people got confused so they swapped it and now do the full panel testing and pay for third party testing partial panel.

        M Online
        M Online
        mikebricker
        wrote last edited by mikebricker
        #34

        @Stevepep How to check third party testing? I’m not sure exactly what you mean?
        Also Steve please refer me to how you know they own a Chinese API manufacturer and get the powder in the USA then finish and lyophilize themselves. I can’t find that anywhere with Google. Thanks.
        PS., please don’t say Finnrick. That’s a major joke…

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        • M mikebricker

          @Stevepep How to check third party testing? I’m not sure exactly what you mean?
          Also Steve please refer me to how you know they own a Chinese API manufacturer and get the powder in the USA then finish and lyophilize themselves. I can’t find that anywhere with Google. Thanks.
          PS., please don’t say Finnrick. That’s a major joke…

          S Online
          S Online
          Stevepep
          wrote last edited by Stevepep
          #35

          @mikebricker just follow Cain on telegram he talks about it often so it’s coming from Nexaph. It’s SNP https://t.me/SNPcomm. They have no secrets and are very forthright. There are third party testing results there and also on flying purple

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          • S Stevepep

            @mikebricker just follow Cain on telegram he talks about it often so it’s coming from Nexaph. It’s SNP https://t.me/SNPcomm. They have no secrets and are very forthright. There are third party testing results there and also on flying purple

            M Online
            M Online
            mikebricker
            wrote last edited by
            #36

            @Stevepep I believe you, they have the best most tested deal at very good prices. I wish I’d found them sooner.

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            • M mikebricker

              @Stevepep I believe you, they have the best most tested deal at very good prices. I wish I’d found them sooner.

              S Online
              S Online
              Stevepep
              wrote last edited by
              #37

              @mikebricker me too

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              • AmericanchildA Offline
                AmericanchildA Offline
                Americanchild
                wrote last edited by
                #38

                Just so I am clear this R30 is not a Nexaph product?

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                • M mikebricker

                  One thing about Nexaph I don’t understand is the partial testing on some items of the same peptide.
                  Look at Reta. 10mg only purity/potency/ID. But on the 12mg a full test. Why is that? The suspicious part of me thinks maybe the 10mg had higher than normal Endo?
                  I like Nexaph and they have become my go to. But inquiring minds want to know…?

                  pep_researcherP Offline
                  pep_researcherP Offline
                  pep_researcher
                  wrote last edited by
                  #39

                  @mikebricker Nexaph is switching to full testing on all batches post after mid June. It's posted on their TG clearly.

                  1 Reply Last reply
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                  • E Offline
                    E Offline
                    Eleanor
                    wrote last edited by Eleanor
                    #40

                    I love S1research products! Always good product and good overfill most the time. Never had a problem with them. As Randy says though, "They're good until they're not"; something like that. I will continue to buy singles from them.

                    Proud to be on a gubmint watch list

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                    • P Offline
                      P Offline
                      PeptideEd
                      wrote last edited by
                      #41

                      Nexaph has a new batch of Tesamorelin - sadly still coming in at 97% and change purity 😞

                      RandyR D 2 Replies Last reply
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                      • P PeptideEd

                        Nexaph has a new batch of Tesamorelin - sadly still coming in at 97% and change purity 😞

                        RandyR Offline
                        RandyR Offline
                        Randy
                        wrote last edited by
                        #42

                        @PeptideEd thats shitty. I will say tesa is one of the harder ones to deal with on their end. Unacceptable either way.

                        Maybe its time to hit up our girl Tracy at QSC and get on the real big boy juice 😉

                        "If it doesnt come in a needle. It doesn't work"

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                        • P PeptideEd

                          Nexaph has a new batch of Tesamorelin - sadly still coming in at 97% and change purity 😞

                          D Offline
                          D Offline
                          denti
                          wrote last edited by
                          #43

                          @PeptideEd said:

                          Nexaph has a new batch of Tesamorelin - sadly still coming in at 97% and change purity 😞

                          I wonder what happened with 2 batches in a row for them? All previous batches I've bought from Nexaph has been 99%+.

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                          • bobsB Offline
                            bobsB Offline
                            bobs
                            wrote last edited by bobs
                            #44

                            It's that small peak that's a little off. 3.704 vs. 3.763 minutes, that makes those 2%. I wonder what is it?

                            6b1eab5a-c7b1-4e31-ba9c-b5377238fda8-image.jpeg

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                            • bobsB Offline
                              bobsB Offline
                              bobs
                              wrote last edited by
                              #45

                              AI suggests that the small 2% peak appearing slightly earlier than the main peak is most likely an oxidized variant of the peptide (specifically at the Met27 position), or less commonly, a synthesis deletion sequence that left the chain slightly more polar. Neither of these indicates external contaminants; they are simply minor structural variations of the Tesamorelin molecule itself.

                              N 1 Reply Last reply
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                              • bobsB bobs

                                AI suggests that the small 2% peak appearing slightly earlier than the main peak is most likely an oxidized variant of the peptide (specifically at the Met27 position), or less commonly, a synthesis deletion sequence that left the chain slightly more polar. Neither of these indicates external contaminants; they are simply minor structural variations of the Tesamorelin molecule itself.

                                N Offline
                                N Offline
                                Neil McCauley
                                wrote last edited by Neil McCauley
                                #46

                                @bobs said:

                                AI suggests that the small 2% peak appearing slightly earlier than the main peak is most likely an oxidized variant of the peptide (specifically at the Met27 position), or less commonly, a synthesis deletion sequence that left the chain slightly more polar. Neither of these indicates external contaminants; they are simply minor structural variations of the Tesamorelin molecule itself.

                                Exactly. Broken chains of proteins can affect the purity, big-time. At first glance looking at something that says 97% , one might assume there's a sterility/contaminent issue, but often it's not. Think of it more as a potency issue.

                                This doesn't mean it gets a pass btw. At $288 for a kit, for that price I would expect 99%

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                                • D denti

                                  @PeptideEd said:

                                  Nexaph has a new batch of Tesamorelin - sadly still coming in at 97% and change purity 😞

                                  I wonder what happened with 2 batches in a row for them? All previous batches I've bought from Nexaph has been 99%+.

                                  J Online
                                  J Online
                                  jdot
                                  wrote last edited by
                                  #47

                                  @denti It’s claimed that Jano has changed how they test and count certain excipients toward purity.

                                  Not sure how that makes sense, as other vendors are showing Tesa tests through Nexaph at normal high purity without change.

                                  S 1 Reply Last reply
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                                  • J jdot

                                    @denti It’s claimed that Jano has changed how they test and count certain excipients toward purity.

                                    Not sure how that makes sense, as other vendors are showing Tesa tests through Nexaph at normal high purity without change.

                                    S Online
                                    S Online
                                    Stevepep
                                    wrote last edited by Stevepep
                                    #48

                                    @Randy Easy fix: they could just send it to Freedom and get that 99.7pct purity. Easy Peasy

                                    RandyR 1 Reply Last reply
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                                    • N Neil McCauley

                                      @bobs said:

                                      AI suggests that the small 2% peak appearing slightly earlier than the main peak is most likely an oxidized variant of the peptide (specifically at the Met27 position), or less commonly, a synthesis deletion sequence that left the chain slightly more polar. Neither of these indicates external contaminants; they are simply minor structural variations of the Tesamorelin molecule itself.

                                      Exactly. Broken chains of proteins can affect the purity, big-time. At first glance looking at something that says 97% , one might assume there's a sterility/contaminent issue, but often it's not. Think of it more as a potency issue.

                                      This doesn't mean it gets a pass btw. At $288 for a kit, for that price I would expect 99%

                                      S Online
                                      S Online
                                      Stevepep
                                      wrote last edited by Stevepep
                                      #49

                                      @Neil-McCauley I wouldn't buy it, but think about how many peptides are bought with 97pct or less purity that show a COA of 99 plus from other retailers that use low quality labs. Nexaph has the perfect example of that: on their last batch of Tesa, they could have just used the Freedom 99.7pct results and not shown the Jano 97pct results, and a lot of people would have bought it hook, line, and sinker, as they do from other retailers they purchase from.

                                      J 1 Reply Last reply
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                                      • RandyR Randy

                                        @PeptideEd thats shitty. I will say tesa is one of the harder ones to deal with on their end. Unacceptable either way.

                                        Maybe its time to hit up our girl Tracy at QSC and get on the real big boy juice 😉

                                        M Offline
                                        M Offline
                                        mary
                                        wrote last edited by
                                        #50
                                        This post is deleted!
                                        RandyR 1 Reply Last reply
                                        0
                                        • S Stevepep

                                          @Neil-McCauley I wouldn't buy it, but think about how many peptides are bought with 97pct or less purity that show a COA of 99 plus from other retailers that use low quality labs. Nexaph has the perfect example of that: on their last batch of Tesa, they could have just used the Freedom 99.7pct results and not shown the Jano 97pct results, and a lot of people would have bought it hook, line, and sinker, as they do from other retailers they purchase from.

                                          J Online
                                          J Online
                                          jdot
                                          wrote last edited by
                                          #51

                                          @Stevepep Are any of you curious why their Tesa is testing below 98%?

                                          I mean, we know Nexaph is essentially a manufacturer that typically puts out top notch product.

                                          All the sudden they’re getting lower quality raws? Is it something in the way they’re finishing?

                                          S 1 Reply Last reply
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