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Nexaph testing

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  • S Stevepep

    @mikebricker just follow Cain on telegram he talks about it often so it’s coming from Nexaph. It’s SNP https://t.me/SNPcomm. They have no secrets and are very forthright. There are third party testing results there and also on flying purple

    M Online
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    mikebricker
    wrote last edited by
    #36

    @Stevepep I believe you, they have the best most tested deal at very good prices. I wish I’d found them sooner.

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    • M mikebricker

      @Stevepep I believe you, they have the best most tested deal at very good prices. I wish I’d found them sooner.

      S Online
      S Online
      Stevepep
      wrote last edited by
      #37

      @mikebricker me too

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      • AmericanchildA Offline
        AmericanchildA Offline
        Americanchild
        wrote last edited by
        #38

        Just so I am clear this R30 is not a Nexaph product?

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        • M mikebricker

          One thing about Nexaph I don’t understand is the partial testing on some items of the same peptide.
          Look at Reta. 10mg only purity/potency/ID. But on the 12mg a full test. Why is that? The suspicious part of me thinks maybe the 10mg had higher than normal Endo?
          I like Nexaph and they have become my go to. But inquiring minds want to know…?

          pep_researcherP Offline
          pep_researcherP Offline
          pep_researcher
          wrote last edited by
          #39

          @mikebricker Nexaph is switching to full testing on all batches post after mid June. It's posted on their TG clearly.

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          • E Offline
            E Offline
            Eleanor
            wrote last edited by Eleanor
            #40

            I love S1research products! Always good product and good overfill most the time. Never had a problem with them. As Randy says though, "They're good until they're not"; something like that. I will continue to buy singles from them.

            Proud to be on a gubmint watch list

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            • P Offline
              P Offline
              PeptideEd
              wrote last edited by
              #41

              Nexaph has a new batch of Tesamorelin - sadly still coming in at 97% and change purity 😞

              RandyR D 2 Replies Last reply
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              • P PeptideEd

                Nexaph has a new batch of Tesamorelin - sadly still coming in at 97% and change purity 😞

                RandyR Offline
                RandyR Offline
                Randy
                wrote last edited by
                #42

                @PeptideEd thats shitty. I will say tesa is one of the harder ones to deal with on their end. Unacceptable either way.

                Maybe its time to hit up our girl Tracy at QSC and get on the real big boy juice 😉

                "If it doesnt come in a needle. It doesn't work"

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                • P PeptideEd

                  Nexaph has a new batch of Tesamorelin - sadly still coming in at 97% and change purity 😞

                  D Offline
                  D Offline
                  denti
                  wrote last edited by
                  #43

                  @PeptideEd said:

                  Nexaph has a new batch of Tesamorelin - sadly still coming in at 97% and change purity 😞

                  I wonder what happened with 2 batches in a row for them? All previous batches I've bought from Nexaph has been 99%+.

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                  • bobsB Offline
                    bobsB Offline
                    bobs
                    wrote last edited by bobs
                    #44

                    It's that small peak that's a little off. 3.704 vs. 3.763 minutes, that makes those 2%. I wonder what is it?

                    6b1eab5a-c7b1-4e31-ba9c-b5377238fda8-image.jpeg

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                    • bobsB Offline
                      bobsB Offline
                      bobs
                      wrote last edited by
                      #45

                      AI suggests that the small 2% peak appearing slightly earlier than the main peak is most likely an oxidized variant of the peptide (specifically at the Met27 position), or less commonly, a synthesis deletion sequence that left the chain slightly more polar. Neither of these indicates external contaminants; they are simply minor structural variations of the Tesamorelin molecule itself.

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                      • bobsB bobs

                        AI suggests that the small 2% peak appearing slightly earlier than the main peak is most likely an oxidized variant of the peptide (specifically at the Met27 position), or less commonly, a synthesis deletion sequence that left the chain slightly more polar. Neither of these indicates external contaminants; they are simply minor structural variations of the Tesamorelin molecule itself.

                        N Offline
                        N Offline
                        Neil McCauley
                        wrote last edited by Neil McCauley
                        #46

                        @bobs said:

                        AI suggests that the small 2% peak appearing slightly earlier than the main peak is most likely an oxidized variant of the peptide (specifically at the Met27 position), or less commonly, a synthesis deletion sequence that left the chain slightly more polar. Neither of these indicates external contaminants; they are simply minor structural variations of the Tesamorelin molecule itself.

                        Exactly. Broken chains of proteins can affect the purity, big-time. At first glance looking at something that says 97% , one might assume there's a sterility/contaminent issue, but often it's not. Think of it more as a potency issue.

                        This doesn't mean it gets a pass btw. At $288 for a kit, for that price I would expect 99%

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                        • D denti

                          @PeptideEd said:

                          Nexaph has a new batch of Tesamorelin - sadly still coming in at 97% and change purity 😞

                          I wonder what happened with 2 batches in a row for them? All previous batches I've bought from Nexaph has been 99%+.

                          J Online
                          J Online
                          jdot
                          wrote last edited by
                          #47

                          @denti It’s claimed that Jano has changed how they test and count certain excipients toward purity.

                          Not sure how that makes sense, as other vendors are showing Tesa tests through Nexaph at normal high purity without change.

                          S 1 Reply Last reply
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                          • J jdot

                            @denti It’s claimed that Jano has changed how they test and count certain excipients toward purity.

                            Not sure how that makes sense, as other vendors are showing Tesa tests through Nexaph at normal high purity without change.

                            S Online
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                            Stevepep
                            wrote last edited by Stevepep
                            #48

                            @Randy Easy fix: they could just send it to Freedom and get that 99.7pct purity. Easy Peasy

                            RandyR 1 Reply Last reply
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                            • N Neil McCauley

                              @bobs said:

                              AI suggests that the small 2% peak appearing slightly earlier than the main peak is most likely an oxidized variant of the peptide (specifically at the Met27 position), or less commonly, a synthesis deletion sequence that left the chain slightly more polar. Neither of these indicates external contaminants; they are simply minor structural variations of the Tesamorelin molecule itself.

                              Exactly. Broken chains of proteins can affect the purity, big-time. At first glance looking at something that says 97% , one might assume there's a sterility/contaminent issue, but often it's not. Think of it more as a potency issue.

                              This doesn't mean it gets a pass btw. At $288 for a kit, for that price I would expect 99%

                              S Online
                              S Online
                              Stevepep
                              wrote last edited by Stevepep
                              #49

                              @Neil-McCauley I wouldn't buy it, but think about how many peptides are bought with 97pct or less purity that show a COA of 99 plus from other retailers that use low quality labs. Nexaph has the perfect example of that: on their last batch of Tesa, they could have just used the Freedom 99.7pct results and not shown the Jano 97pct results, and a lot of people would have bought it hook, line, and sinker, as they do from other retailers they purchase from.

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                              • RandyR Randy

                                @PeptideEd thats shitty. I will say tesa is one of the harder ones to deal with on their end. Unacceptable either way.

                                Maybe its time to hit up our girl Tracy at QSC and get on the real big boy juice 😉

                                M Offline
                                M Offline
                                mary
                                wrote last edited by
                                #50
                                This post is deleted!
                                RandyR 1 Reply Last reply
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                                • S Stevepep

                                  @Neil-McCauley I wouldn't buy it, but think about how many peptides are bought with 97pct or less purity that show a COA of 99 plus from other retailers that use low quality labs. Nexaph has the perfect example of that: on their last batch of Tesa, they could have just used the Freedom 99.7pct results and not shown the Jano 97pct results, and a lot of people would have bought it hook, line, and sinker, as they do from other retailers they purchase from.

                                  J Online
                                  J Online
                                  jdot
                                  wrote last edited by
                                  #51

                                  @Stevepep Are any of you curious why their Tesa is testing below 98%?

                                  I mean, we know Nexaph is essentially a manufacturer that typically puts out top notch product.

                                  All the sudden they’re getting lower quality raws? Is it something in the way they’re finishing?

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                                  • J jdot

                                    @Stevepep Are any of you curious why their Tesa is testing below 98%?

                                    I mean, we know Nexaph is essentially a manufacturer that typically puts out top notch product.

                                    All the sudden they’re getting lower quality raws? Is it something in the way they’re finishing?

                                    S Online
                                    S Online
                                    Stevepep
                                    wrote last edited by
                                    #52

                                    @Jdot I have asked and the response is along the lines of Tesa is tough not what I was hoping for. At least. we have an honest COA and can make an informed choice. I need Tesa soon so this kind of sucks. I just posted in their telegram as well on this

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                                    • P Offline
                                      P Offline
                                      PeptideEd
                                      wrote last edited by
                                      #53

                                      @stevepep to be clear: while I'm disappointed in the poor purity results for two tesamorelin batches in a row - overall the honesty about it reflects well on Nexaph in my mind.

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                                      • bobsB Offline
                                        bobsB Offline
                                        bobs
                                        wrote last edited by
                                        #54

                                        I wouldn't sweat over 97% knowing it is nothing else but an oxidized or a broken molecule of the same, not any contaminant. The more important to know is that it is the real tesamorelin, it binds to the proper receptors, it is folded correctly, the amino acids are chained in a proper order. No 99.9% COA from Janoshik can guarantee it, it can well be a completely differently connected chain but have the same HPLC and MS results. So, the most important parameter is how trustworthy is the manufacturer.

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                                        • S Online
                                          S Online
                                          Stevepep
                                          wrote last edited by Stevepep
                                          #55

                                          So the response was that the product is Tesa and not to worry about 97pct essentially. That testing standards at different labs can show different results and to reach out to Janoshik which I have done. I emailed them to see what’s up.basically what @bobs said

                                          bobsB 1 Reply Last reply
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