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Peptide Critic Community

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  4. CJC-1295 NO DAC (Mod GRF 1–29) Research Dosing Protocol
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CJC-1295 NO DAC (Mod GRF 1–29) Research Dosing Protocol

Scheduled Pinned Locked Moved Growth & Performance
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  • RandyR Offline
    RandyR Offline
    Randy
    wrote on last edited by
    #1

    For research use only. Not medical advice.

    Overview

    CJC-1295 NO DAC (Modified GRF 1–29) is a short-acting GHRH analog with a ~30-minute half-life that produces physiologic GH pulses rather than sustained elevation.
    Because of its short duration, it is typically administered once daily to support natural GH rhythm, or stacked with GH secretagogues like ipamorelin for synergistic pulses.

    Daily Dosing Protocol (Subcutaneous)

    Standard Daily Range

    100–300 mcg once daily

    Researchers generally start low and increase gradually to minimize flushing and injection-site irritation.

    Titration Schedule

    Weeks 1–2

    100 mcg daily

    Establishes baseline tolerability.

    Weeks 3–4

    150 mcg daily

    Weeks 5–6

    200 mcg daily

    Weeks 7–8

    250 mcg daily

    Weeks 9–10

    300 mcg daily

    Common upper end of daily dosing for standalone CJC-1295 NO DAC protocols.

    Timing

    Typically administered before bedtime to align with nocturnal GH release.

    Can also be paired with ipamorelin or other GHRPs taken at the same time for a stronger GH pulse.

    Alternative timing strategies used in some research settings:

    Morning fasted

    Post-workout

    2–3× per day micro-pulsing (advanced protocols; not necessary for standard use)

    Cycle Length

    Typical Mod GRF 1–29 research cycles:

    8–12 weeks on, followed by

    2–4 weeks off to reduce receptor fatigue

    Longer cycles are common when stacked with GHRPs.

    Common Research Notes

    Produces clean GH pulses without the water retention sometimes seen with long-acting GH analogs.

    Stacks exceptionally well with ipamorelin, GHRP-2, or GHRP-6 for dual-pathway GH stimulation.

    Side effects are usually mild: warmth, flushing, or transient lightheadedness shortly after administration.

    Should be taken away from food, as nutrients—especially carbs/fats—may blunt GH output.

    "If it doesnt come in a needle. It doesn't work"

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    • M Offline
      M Offline
      MdK949
      wrote on last edited by
      #2

      Just started this two weeks ago. Really good to see this protocol. It aligns with what I found on PeptideGPT.

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      • J Offline
        J Offline
        jaykirby
        wrote last edited by
        #3

        i stated taking this 4 nights ago. My vial is mixed 5mg CJC, 5mg Ipamorelin. My sleeps have been nice and deep. I usually wake up for a bit pee around 4am but i have found that common since starting all of my other peptides Jan 20th.

        I look forward to seeing how I progress with this.

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        • MyBM Offline
          MyBM Offline
          MyB
          wrote last edited by
          #4

          Dr Ashley Froese dropped a video yesterday about CJC-1295 and how ipamorelin work well together
          https://youtu.be/kdQ83_Je_qs?si=oen7AtRAJamxzZgF

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          • R Offline
            R Offline
            ResearchCat
            wrote last edited by
            #5

            She’s blowing up. Her videos are great. I wonder when/if she is going to get into telehealth. (Though, she is not a chiropractor so she may not be qualified to prescribe peptide therapies.) 😉

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            • RandyR Offline
              RandyR Offline
              Randy
              wrote last edited by
              #6

              She's the real deal. The only thing id add is to research them separately first. Reactions to cjc arent rare and ipa does happen. Its best to know which one if you were to have a bad time.

              "If it doesnt come in a needle. It doesn't work"

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