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Glutathione (GSH) Subcutaneous Research Dosing Protocol

Scheduled Pinned Locked Moved Peptide Discussion
glutathioneresearching
117 Posts 30 Posters 17.2k Views 11 Watching
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  • WisGal64W Offline
    WisGal64W Offline
    WisGal64
    wrote last edited by
    #79

    @myb thank you

    “Not a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

    1 Reply Last reply
    0
    • MyBM MyB

      For the price of two bottles from southern you could buy a case shipped from Korean beauty supply places like Acecosm.

      mrjoshua44M Offline
      mrjoshua44M Offline
      mrjoshua44
      wrote last edited by
      #80

      @MyB Sure, but with the way things are at with Customs now, it would be my luck my shipment gets hung up or I just won't see it. Plus I got my package in two days. That's worth it to me rather than taking the gamble of $90 and I may or may not even get my order.

      1 Reply Last reply
      0
      • WisGal64W Offline
        WisGal64W Offline
        WisGal64
        wrote last edited by
        #81

        @myb I read the specs, it says it whitens skin? Does it really do that?

        “Not a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

        K 1 Reply Last reply
        0
        • MyBM Offline
          MyBM Offline
          MyB
          wrote last edited by
          #82

          @wisgal64 when injected into the skin doing mesotherapy it can. Fair skin is a goal for some people darker than “white”. The antioxidants help prevent sun damage aka tanning.

          Follows research backed science, not “trust me” bro’s.

          1 Reply Last reply
          1
          • WisGal64W WisGal64

            @myb I read the specs, it says it whitens skin? Does it really do that?

            K Offline
            K Offline
            keurimm
            wrote last edited by
            #83

            @WisGal64 i've been trying to read up on subcutaneous results since i only have experience with IV infusions but even after just two session IV infusion skin was noticeably lighter. I honestly had no purpose to get the infusions also, just joined my mother (and her rat?) because she said it was for her liver health and brother wanted practice placing IV's lol. going into this rabbit hole made me realize i've been using peptides longer than i thought i have been hahaha

            mrjoshua44M 1 Reply Last reply
            1
            • K keurimm

              @WisGal64 i've been trying to read up on subcutaneous results since i only have experience with IV infusions but even after just two session IV infusion skin was noticeably lighter. I honestly had no purpose to get the infusions also, just joined my mother (and her rat?) because she said it was for her liver health and brother wanted practice placing IV's lol. going into this rabbit hole made me realize i've been using peptides longer than i thought i have been hahaha

              mrjoshua44M Offline
              mrjoshua44M Offline
              mrjoshua44
              wrote last edited by
              #84

              @keurimm My rat prefers his Glutathione IM, 400mg-500mg 3x per week in the thigh or glute. It's good stuff! Haven't been sick once, no seasonal allergies and skin that's never looked better.

              B 1 Reply Last reply
              0
              • J Offline
                J Offline
                jackiee
                wrote last edited by
                #85

                @wisgal64 , hmmm....sounds like using this and MT1 might be counterintuitive?

                1 Reply Last reply
                0
                • WisGal64W Offline
                  WisGal64W Offline
                  WisGal64
                  wrote last edited by
                  #86

                  @jackiewatson ya, this is where I’m at, definitely don’t want to run together. I want the benefits of both but will have to do some more research

                  “Not a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

                  1 Reply Last reply
                  0
                  • B brandenscheidecker

                    anyone have a source for Fuan?

                    J Offline
                    J Offline
                    JNader66
                    wrote last edited by
                    #87

                    @brandenscheidecker
                    I got some from Mile High recently.

                    1 Reply Last reply
                    1
                    • mrjoshua44M mrjoshua44

                      Just got delivered some of that Korean Glutathione from Southern Aminos. I believe I snagged their last one. Now on to finish my quest of finding some Fuan Glutathione.

                      IMG_0608.jpeg

                      B Offline
                      B Offline
                      beachfun
                      wrote last edited by
                      #88

                      @mrjoshua44 That is exactly what I bought…how many ml of bac water and units are you planning on running?

                      mrjoshua44M 1 Reply Last reply
                      1
                      • mrjoshua44M mrjoshua44

                        @keurimm My rat prefers his Glutathione IM, 400mg-500mg 3x per week in the thigh or glute. It's good stuff! Haven't been sick once, no seasonal allergies and skin that's never looked better.

                        B Offline
                        B Offline
                        beachfun
                        wrote last edited by
                        #89

                        @mrjoshua44 I guess I could go do the math on the calculator but wondering how you are reconstituting to get that dose. Any burn like copper or NAD?

                        1 Reply Last reply
                        0
                        • B beachfun

                          @mrjoshua44 That is exactly what I bought…how many ml of bac water and units are you planning on running?

                          mrjoshua44M Offline
                          mrjoshua44M Offline
                          mrjoshua44
                          wrote last edited by
                          #90

                          @beachfun I used 9mL's of GTB water since it was my first time reconstituting glutathione. Probably could've used less but that's ok. Haven't tried it yet, my first dose will be later today. But that GTB water has taurine in it so it's supposed to take the bite out of the shot. Anyway, I have my dose set at 200mg which in this concentration is 150cc/units or 1.5mL. But since I normally pin 400mg 3x a week, I'll be pushing 300cc/units or 3mL's IM.
                          IMG_0653.jpeg

                          B 2 Replies Last reply
                          1
                          • mrjoshua44M Offline
                            mrjoshua44M Offline
                            mrjoshua44
                            wrote last edited by
                            #91

                            Yay! Just got a couple of purple tops delivered.
                            IMG_0667.jpeg

                            R 1 Reply Last reply
                            1
                            • E Offline
                              E Offline
                              Eleanor
                              wrote last edited by
                              #92

                              I would LOVE to do Glutathione subq. I got infusions which had more B12 than anything, IMO. Please let me know if you dd subq and your recipe and how it turned out.

                              I asked my Dr. about this, "Since Gluta speeds up detox in phase two, it shouldn't speed up the detox of other peptides, should it?" She didn't know how to answer this; wasn't sure.

                              Proud to be on a gubmint watch list

                              mrjoshua44M 1 Reply Last reply
                              1
                              • mrjoshua44M Offline
                                mrjoshua44M Offline
                                mrjoshua44
                                wrote last edited by
                                #93
                                This post is deleted!
                                1 Reply Last reply
                                0
                                • E Eleanor

                                  I would LOVE to do Glutathione subq. I got infusions which had more B12 than anything, IMO. Please let me know if you dd subq and your recipe and how it turned out.

                                  I asked my Dr. about this, "Since Gluta speeds up detox in phase two, it shouldn't speed up the detox of other peptides, should it?" She didn't know how to answer this; wasn't sure.

                                  mrjoshua44M Offline
                                  mrjoshua44M Offline
                                  mrjoshua44
                                  wrote last edited by
                                  #94

                                  @Eleanor I mainly pin my Glutathione IM in either my thigh or glutes. And that's due to the volume of the injection. I just reconstituted a 1200mg vial the other day using GTB water (Glutathione Transport Bacteriostatic Water). I used 9mL's of GTB. So that solution came out to be 133.33mg/mL and my dose is 200mg. And that worked out to be 150 Units or 1.5mL. I try not to pin anything SubQ that's going to be more than 100 units or 1mL. Next time I'm going to decrease the amount of mL's used to reconstitute it. To answer your second question, no. It does not affect other peptides.

                                  Here is why it doesn't arbitrarily speed up the detox/clearance of other peptides:

                                  Different Processing Pathways: Peptides are chains of amino acids. The breakdown and clearance of specific functional peptides are generally handled by specialized enzymes (like peptidases and proteases) spread throughout the blood and tissues, not just the liver's Phase 2 detox pathways.

                                  Specialized Conjugation: In Phase 2, Glutathione S-transferase (GST) enzymes only attach glutathione to specific electrophilic (reactive) toxins or free radicals to make them water-soluble. It generally does not bind to or speed up the degradation of beneficial peptides.

                                  Biological Targets: Rather than breaking other peptides down, Glutathione often interacts with them synergistically. It serves as a master antioxidant to protect them from free radical damage and oxidative stress so they can properly bind to their intended cell receptors.

                                  E 1 Reply Last reply
                                  1
                                  • mrjoshua44M mrjoshua44

                                    @Eleanor I mainly pin my Glutathione IM in either my thigh or glutes. And that's due to the volume of the injection. I just reconstituted a 1200mg vial the other day using GTB water (Glutathione Transport Bacteriostatic Water). I used 9mL's of GTB. So that solution came out to be 133.33mg/mL and my dose is 200mg. And that worked out to be 150 Units or 1.5mL. I try not to pin anything SubQ that's going to be more than 100 units or 1mL. Next time I'm going to decrease the amount of mL's used to reconstitute it. To answer your second question, no. It does not affect other peptides.

                                    Here is why it doesn't arbitrarily speed up the detox/clearance of other peptides:

                                    Different Processing Pathways: Peptides are chains of amino acids. The breakdown and clearance of specific functional peptides are generally handled by specialized enzymes (like peptidases and proteases) spread throughout the blood and tissues, not just the liver's Phase 2 detox pathways.

                                    Specialized Conjugation: In Phase 2, Glutathione S-transferase (GST) enzymes only attach glutathione to specific electrophilic (reactive) toxins or free radicals to make them water-soluble. It generally does not bind to or speed up the degradation of beneficial peptides.

                                    Biological Targets: Rather than breaking other peptides down, Glutathione often interacts with them synergistically. It serves as a master antioxidant to protect them from free radical damage and oxidative stress so they can properly bind to their intended cell receptors.

                                    E Offline
                                    E Offline
                                    Eleanor
                                    wrote last edited by
                                    #95

                                    @mrjoshua44 Thank you, Sir! Excellent information. I don't like IM's because as a redhead, I bruise easily and I never seem to get the poke 100% right.

                                    How many times per week to you pin?

                                    Proud to be on a gubmint watch list

                                    mrjoshua44M 1 Reply Last reply
                                    1
                                    • E Eleanor

                                      @mrjoshua44 Thank you, Sir! Excellent information. I don't like IM's because as a redhead, I bruise easily and I never seem to get the poke 100% right.

                                      How many times per week to you pin?

                                      mrjoshua44M Offline
                                      mrjoshua44M Offline
                                      mrjoshua44
                                      wrote last edited by
                                      #96

                                      @Eleanor 3x per week.

                                      1 Reply Last reply
                                      1
                                      • mrjoshua44M mrjoshua44

                                        @beachfun I used 9mL's of GTB water since it was my first time reconstituting glutathione. Probably could've used less but that's ok. Haven't tried it yet, my first dose will be later today. But that GTB water has taurine in it so it's supposed to take the bite out of the shot. Anyway, I have my dose set at 200mg which in this concentration is 150cc/units or 1.5mL. But since I normally pin 400mg 3x a week, I'll be pushing 300cc/units or 3mL's IM.
                                        IMG_0653.jpeg

                                        B Offline
                                        B Offline
                                        beachfun
                                        wrote last edited by
                                        #97

                                        @mrjoshua44 I have that Korean Glutathione but not the bac water for it. Going to the clinic tomorrow so will see if they can get me started. Thanks so it looks like a IM shot

                                        1 Reply Last reply
                                        1
                                        • mrjoshua44M mrjoshua44

                                          @beachfun I used 9mL's of GTB water since it was my first time reconstituting glutathione. Probably could've used less but that's ok. Haven't tried it yet, my first dose will be later today. But that GTB water has taurine in it so it's supposed to take the bite out of the shot. Anyway, I have my dose set at 200mg which in this concentration is 150cc/units or 1.5mL. But since I normally pin 400mg 3x a week, I'll be pushing 300cc/units or 3mL's IM.
                                          IMG_0653.jpeg

                                          B Offline
                                          B Offline
                                          beachfun
                                          wrote last edited by
                                          #98

                                          @mrjoshua44 I have that Korean Glutathione but not the bac water for it. Going to the clinic tomorrow so will see if they can get me started. Thanks so it looks like a IM shot

                                          1 Reply Last reply
                                          1

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