Klotho / FLGR242 (albumin-bound new tech)
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Well I don't think you'll disappointed. While I was doing my own research, it was Pete's posting way back in Dec/Jan that gave me the courage to eventually lay out the $$$$ and go for it! It's been impressive and I've been going easy on the protocol until recently. So by the time you make your decision I might be able to add some additional data points if I truly cycle off. On the other hand I'm also researching some other things I might try during that break so....... Ya, I've got a problem!
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Have yall seen the te cartel video? Was 4 months old but relevant https://youtu.be/mKkha0OJxLQ?si=oPZOFzkVFl7np_Ua
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@PeptidePete Yes! I have been using both for about 6 months. I honestly can't say how much I feel with the Klotho, but it's more about blood work anyway. I have better Kidney function and my blood markers show that since starting. Don't know if it's worth the money since I don't have significant health issues that Klotho would address anyway. But it is supposed to be the longevity peptide.
The FLGR 242, a different story. It has allowed me to drop Reta to a microdose since it burns fat so effectively. I'm a 61 year old man and have been on TRT for 6 years. Since taking the FLGR-242, I have put on more muscle and gotten ripped. I have always worked out and had good muscle size. Now it is a little bigger and like I said, ripped.
Klotho may be doing other amazing things that I don't see. That's why I still take it, but I am taking the FLGR 242 because of the results I can see. It's really a fantastic product! Hope that helps.
@PeptidePete Yes! I have been using both for about 6 months. I honestly can't say how much I feel with the Klotho, but it's more about blood work anyway. I have better Kidney function and my blood markers show that since starting. Don't know if it's worth the money since I don't have significant health issues that Klotho would address anyway. But it is supposed to be the longevity peptide.
The FLGR 242, a different story. It has allowed me to drop Reta to a microdose since it burns fat so effectively. I'm a 61 year old man and have been on TRT for 6 years. Since taking the FLGR-242, I have put on more muscle and gotten ripped. I have always worked out and had good muscle size. Now it is a little bigger and like I said, ripped.
Klotho may be doing other amazing things that I don't see. That's why I still take it, but I am taking the FLGR 242 because of the results I can see. It's really a fantastic product! Hope that helps.
Wow! Here's to ripped "old" guys! lol
Great post, full agreement
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@djoelcassell hey Joel.
I do klotho and i split it to 1 a week instead of every 2 weeks.
Has there been any changes were its best 2x a week?
And also i do it subq, is it better IM?
Thanks
@djoelcassell hey Joel.
I do klotho and i split it to 1 a week instead of every 2 weeks.
Has there been any changes were its best 2x a week?
And also i do it subq, is it better IM?
Thanks
Please be very careful with "excess" Klotho dosing, too much is said to potentially cause big problems. The inventor (75 y/o and one kidney) is being aggressive and "only" dosing a vial every 12 days instead of 14. I would respectfully suggest a vial per week is far too close to the "edge", with all risk and no benefits. Cheers friend!
I just realized I think you mean 1/2 vial per week in which case the risk of excess dose is removed, however now you have risk of degradation while half-vial is reconstituted and sits in fridge. No proof of this, just risky and expensive mistake if it does degrade.
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Im doing it based off the last video they did.
1 vial was for 11 days. I split the vial and do it 1/2 vial every 7 days .
I really dont think a peptide should have degradation for 7 days mixed.
Are you just doing every 11 days?
Thanks
DiegoIm doing it based off the last video they did.
1 vial was for 11 days. I split the vial and do it 1/2 vial every 7 days .
I really dont think a peptide should have degradation for 7 days mixed.
Are you just doing every 11 days?
Thanks
DiegoGotcha. Every 12 days, one vial a-Klotho.
Side note- for research purposes I have dropped back to 5mg FLGR once per week.
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@djoelcassell hey Joel.
I do klotho and i split it to 1 a week instead of every 2 weeks.
Has there been any changes were its best 2x a week?
And also i do it subq, is it better IM?
Thanks
Please be very careful with "excess" Klotho dosing, too much is said to potentially cause big problems. The inventor (75 y/o and one kidney) is being aggressive and "only" dosing a vial every 12 days instead of 14. I would respectfully suggest a vial per week is far too close to the "edge", with all risk and no benefits. Cheers friend!
I just realized I think you mean 1/2 vial per week in which case the risk of excess dose is removed, however now you have risk of degradation while half-vial is reconstituted and sits in fridge. No proof of this, just risky and expensive mistake if it does degrade.
@PeptidePete Hello!
I can't say for sure if it's "better" IM. When I look at the research most of the injections were IM, so to be on the safe side I do it that way.
Since you've been Sub-Q'ing, maybe you could inject IM for six weeks and see if there are changes. I'd be interested to see. THis stuff ain't cheap though, so I don't really want to experiment. LolGood luck with it! I'm going to keep doing both Klotho and FLGR-242 for now. Still seeing great results from the FLGR-242! I now know enough people who are all gaining with it to say it is a fantastic compound!
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@djoelcassell hey Joel.
I do klotho and i split it to 1 a week instead of every 2 weeks.
Has there been any changes were its best 2x a week?
And also i do it subq, is it better IM?
Thanks
@diegoc Hello there!
I was part of the Jay Campbell's inner sanctum group for awhile and Jay saw tremendous gains from doing it daily. He was doing it bi-weekly then changed to daily to test it. When he did he saw immediate gains and benefits. There was a lot of conversation between many experienced users and I just watched and listened. I thought it could have been that when Jay changed from q 2 weeks to q day he had just reached a level in his system that would have taken him there anyway. The inventor of FLGR-242 (mike) gave a few reasons why taking it more frequently could be better, but was skeptical. I thought the same. So I tried it three times per week (from once every two weeks) and I did see more of the fat loss benefit, but my muscle gains did not increase. I am now at two times per week since reaching a point that I didn't want to lose any more fat and I've backed off on my dosage to 2.5mg. I'm still seeing muscle gains, so I've actually had to alter my workouts so I don't grow anymore.
There is no definitive proof that taking it more frequently helps in muscle growth, but there is experiential and anecdotal evidence that taking it more frequently will shred you better.Hope that helps!
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@PeptidePete Hello!
I can't say for sure if it's "better" IM. When I look at the research most of the injections were IM, so to be on the safe side I do it that way.
Since you've been Sub-Q'ing, maybe you could inject IM for six weeks and see if there are changes. I'd be interested to see. THis stuff ain't cheap though, so I don't really want to experiment. LolGood luck with it! I'm going to keep doing both Klotho and FLGR-242 for now. Still seeing great results from the FLGR-242! I now know enough people who are all gaining with it to say it is a fantastic compound!
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Definitely do not do FLGR IM. Albumin binder expands there and hurts like a mother. Can't speak to klotho.
Doing flgr 1mg daily M-F, so 5mg a week. I'm certain the compound behaves in a dose dependent fashion as the last 3-4 weeks have been amazing for gains. But you still have to be mindful of what's happening in your body. My weekly total weight on Tonal went up 25k during that time and I almost didn't realize it. Kept doing extra reps. Then extra full sets. Tonal kept adding weight with its algorithm. All I wanted to do was lift! Then neural fatigue kicked in. Was sleeping less, etc. Long story short, I'm taking at least a week to deload (half weight and half sets) and rest more. Once accomplished then back at it- with more strategic and planned recovery weeks on the calendar. -
I don't know if anyone has mentioned it here before but there is an on-going 15% discount on FGLR with the code “JFDISCOUNT"
@TrueNorth
Curious if you know if that code stacks with 'JayC' which is the typical 15% discount code that works for almost anything on the BLL site? -
@TrueNorth
Curious if you know if that code stacks with 'JayC' which is the typical 15% discount code that works for almost anything on the BLL site? -
Fascinating stuff though.
https://share.google/WJmBtqKd92G5LOuX9 -
Josh doesn't know jack about this one. If he tries it for 4 months and then says it doesn't work it will confirm he's a buffoon. If he actually did a trial most likely he'd have to make another video with 'I was wrong' in the title. I sense this might be up your alley though!
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Josh doesn't know jack about this one. If he tries it for 4 months and then says it doesn't work it will confirm he's a buffoon. If he actually did a trial most likely he'd have to make another video with 'I was wrong' in the title. I sense this might be up your alley though!
Josh doesn't know jack about this one. If he tries it for 4 months and then says it doesn't work it will confirm he's a buffoon. If he actually did a trial most likely he'd have to make another video with 'I was wrong' in the title. I sense this might be up your alley though!
That video tells me everything I need to know...about the person who created the video. Zero credibility. A buffoon.
On a side note, for research purposes, I am shifting to 2.5mg FLGR once per week starting tomorrow (2.5mg every Monday). Just completing a wash-out week to set up for the change. My wife will remain on 2.5mg per week, so we just split a vial per week.
If. IF, FLGR242 response curves parallel the Bimagrumab results, a good possibility but not yet known as fact, then half a year gives me the vast majority of the benefits, and I can taper back until we have a year of more of continued lack of negative signals. In other words, play cautious simply for the sake of doing so until BioLongevityLabs publishes results of currently ongoing human testing.
Last week I did another round of labs and for example my PSA remains unchanged at 0.5, so prostate is happy. Rest of labs look as expected with no surprises, in spite of being on a TRT++ protocol for three months + FLGR, so a worst case, or depending how you look at it, a best case (lol!) scenario.
I remain a researcher of Klotho at one vial per 13 days.
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Just an update. Yes, I realized that Paramount is the out facing vendor for Alpha BioMed, which erroneously publishes that alpha-Klotho LR (MAB) is a monoclonal antibody, which it is not! I just messaged Mike Farber on LinkedIn, and he responded within minutes.
I am now researching both FLGR-242 (5mg) and a-Klotho LR (10 mcg). I purchased from BLL. Both with discounts came to about $174.57/vial.
Chronological age: 66.3-yrs-old. TruAge OMICmAge = 60.8. Symphony Age 62.3. Telomere Biological Age 69.1.
I have since done two rounds of Epithalon + Thymalin. I also take TA65 Rx 500 QD. Pinning Testosterone Cypionate 20U (40 mg) sub-Q every other day--just switched from IM twice a week.
One round of Senolytic FOXO4-DRI.
Cycling Tesa/Ipa - 2mg/200mcg 5d on/2d off.
Started alpha-Klotho 10 mcg Q 2 weeks.
Started FLGR-242 initially at 5mg Q wk, but decided to do 2.5 mg twice a week.
Exercising 5x/week - mostly resistance exercises, but will resume using Peloton.
Regularly checking Biomarkers and DEXA scans. Have done GutID and SelfDecode methylation tests.
I just wanted to share baselines so I can report on changes to biomarkers, body composition, etc.
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Just an update. Yes, I realized that Paramount is the out facing vendor for Alpha BioMed, which erroneously publishes that alpha-Klotho LR (MAB) is a monoclonal antibody, which it is not! I just messaged Mike Farber on LinkedIn, and he responded within minutes.
I am now researching both FLGR-242 (5mg) and a-Klotho LR (10 mcg). I purchased from BLL. Both with discounts came to about $174.57/vial.
Chronological age: 66.3-yrs-old. TruAge OMICmAge = 60.8. Symphony Age 62.3. Telomere Biological Age 69.1.
I have since done two rounds of Epithalon + Thymalin. I also take TA65 Rx 500 QD. Pinning Testosterone Cypionate 20U (40 mg) sub-Q every other day--just switched from IM twice a week.
One round of Senolytic FOXO4-DRI.
Cycling Tesa/Ipa - 2mg/200mcg 5d on/2d off.
Started alpha-Klotho 10 mcg Q 2 weeks.
Started FLGR-242 initially at 5mg Q wk, but decided to do 2.5 mg twice a week.
Exercising 5x/week - mostly resistance exercises, but will resume using Peloton.
Regularly checking Biomarkers and DEXA scans. Have done GutID and SelfDecode methylation tests.
I just wanted to share baselines so I can report on changes to biomarkers, body composition, etc.
@ImaFrogNotaRat hey brother.
Just an opinion.
At your age I would do GH instead of the secretagogues
Maybe 2iu would suffice.
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Also check your Total, and Free test like in 2-3 weeks, dont wait months.
Sometimes Test SQ doesn’t absorb well.
@diegoc Thank you for the advice. My goal with the Tesa/Ipa is to reduce visceral fat (3.5 lbs VAT) and reduce inflammatory causes of atherosclerotic CVD. My reluctance to use the GH is my controlled Type 2 Diabetes. I don't want any acute insulin resistance. Are you implying that the GH would be better from an anabolic perspective?
I'm afraid of messing with the HPA axis.
As for the sub-Q testosterone, that's a good point. Presumably that has to get absorbed somewhere. I could always pin my anterior/lateral thigh. I believe even the 1/2" needle would hit the muscle.
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