Skip to content
  • Categories
  • Recent
  • Tags
  • Popular
  • World
  • Users
  • Groups
Skins
  • Light
  • Brite
  • Cerulean
  • Cosmo
  • Flatly
  • Journal
  • Litera
  • Lumen
  • Lux
  • Materia
  • Minty
  • Morph
  • Pulse
  • Sandstone
  • Simplex
  • Sketchy
  • Spacelab
  • United
  • Yeti
  • Zephyr
  • Dark
  • Cyborg
  • Darkly
  • Quartz
  • Slate
  • Solar
  • Superhero
  • Vapor

  • Default (Zephyr)
  • No Skin
Collapse
Peptide Critic Community Peptide Critic Community
  1. Peptide Forum
  2. Peptide Discussion
  3. Klotho / FLGR242 (albumin-bound new tech)
Prize
Three Pens + Filters & Cartridges
Ends in
11995 entries · 4908 participants
Enter →

Klotho / FLGR242 (albumin-bound new tech)

Scheduled Pinned Locked Moved Peptide Discussion
researching
587 Posts 41 Posters 62.9k Views 9 Watching
  • Oldest to Newest
  • Newest to Oldest
  • Most Votes
Reply
  • Reply as topic
Log in to reply
This topic has been deleted. Only users with topic management privileges can see it.
  • D Offline
    D Offline
    denti
    wrote last edited by
    #155

    With the current discount I think I am going to jump in. Been eyeing this for awhile. I may have missed it earlier in this thread, but any suggestions on dosing and how often? I was going to buy the 6 pack so 12 vials.

    1 Reply Last reply
    0
    • quicksilver80Q Online
      quicksilver80Q Online
      quicksilver80
      wrote last edited by
      #156

      I mean 2 vials is a whole ass cycle if i remember correctly from gc and jays talk.. So if i saw it for like 120 a vial id probably bite. Till then. Ill leave it to you rich old farts lol

      1 Reply Last reply
      0
      • D Offline
        D Offline
        denti
        wrote last edited by
        #157

        It's down to 100 a vial with the current discount and JayC coupon buying the 6 pack. Didn't realize 2 vials is a whole cycle. Maybe I will just do that then.

        T 1 Reply Last reply
        0
        • quicksilver80Q Online
          quicksilver80Q Online
          quicksilver80
          wrote last edited by
          #158

          🤔 Well fuck

          1 Reply Last reply
          0
          • D denti

            It's down to 100 a vial with the current discount and JayC coupon buying the 6 pack. Didn't realize 2 vials is a whole cycle. Maybe I will just do that then.

            T Offline
            T Offline
            thanks_enjoi
            wrote last edited by
            #159

            @denti said:

            a

            I would read this topic. You need quite a bit more than 2 vials

            1 Reply Last reply
            1
            • quicksilver80Q Online
              quicksilver80Q Online
              quicksilver80
              wrote last edited by
              #160

              Weird. Must have misheard

              1 Reply Last reply
              0
              • S Stones67

                @quicksilver80 Hi quick! So I would say that it helped weight loss- leaned me out in a way that was different from just losing fat. Before starting FLGR I had lost 20lbs with Reta at a dose of 0.5mg every 6 days. Probably never even benefitted from the glucagon effect with that low dose! But being a hyper-responder has its benefits? When visible changes stalled and the scale wouldn't budge I began to consider Reta might be holding me back from some of the follistatin benefits- you need calories to build muscle. It was time to cycle off reta anyway. The last 5 weeks I've added 4ish lbs which appears to be essentially all muscle. Can't prove it yet as next Dexa isn't until the fall.
                You are correct about the supply chain/ gatekeeping. As I can tell you already know, Follistatin has been known and tried for decades. My understanding is that the patent is on the albumin binder, which extends the half-life to something like 2 weeks, not the follistatin itself. Hence unlikely to be found in the wild for a while. Rejoice in economies of scale though- down $300 for a months supply on BioLongevity Labs due to more efficient production! Hope that helps.

                D Offline
                D Offline
                denti
                wrote last edited by
                #161

                @Stones67 said:

                @quicksilver80 Hi quick! So I would say that it helped weight loss- leaned me out in a way that was different from just losing fat. Before starting FLGR I had lost 20lbs with Reta at a dose of 0.5mg every 6 days. Probably never even benefitted from the glucagon effect with that low dose! But being a hyper-responder has its benefits? When visible changes stalled and the scale wouldn't budge I began to consider Reta might be holding me back from some of the follistatin benefits- you need calories to build muscle. It was time to cycle off reta anyway. The last 5 weeks I've added 4ish lbs which appears to be essentially all muscle. Can't prove it yet as next Dexa isn't until the fall.
                You are correct about the supply chain/ gatekeeping. As I can tell you already know, Follistatin has been known and tried for decades. My understanding is that the patent is on the albumin binder, which extends the half-life to something like 2 weeks, not the follistatin itself. Hence unlikely to be found in the wild for a while. Rejoice in economies of scale though- down $300 for a months supply on BioLongevity Labs due to more efficient production! Hope that helps.

                Stones67 what dosing/timing did you start at and what are you doing now?

                1 Reply Last reply
                0
                • D Offline
                  D Offline
                  denti
                  wrote last edited by
                  #162

                  Ordered 12 vials and will do a 6 month period on FLGR242. Will follow the protocol Stones67 posted above. Here are my starting stats. Just had Dexa and labs done again last week. Will get them again after 12 weeks of FLGR242 and resistance training and again at the end of 24 weeks

                  Male 44
                  Weight 165.2lbs (Weighed 162 that morning on my own scale without clothing and 159lbs today)
                  Body Fat: 18.8%
                  Body Fat: 31 lbs
                  Lean Mass: 127.1 lbs
                  Visceral Fat: 0.60 lbs

                  Testosterone: 513
                  Testosterone Free (Dialysis) 73.6
                  T4 Free: 1.3
                  T3 Free: 2.9
                  IGF 1: 193
                  Z Score: 0.7
                  SHBG: 41

                  Currently no resistance training, but a lot of running with a weighted vest. Will cut down on running and focus mainly resistance training on my Tonal as I feel like I look just soft and skinny fat. Would like to do a body recomposition. Will probably get back on a cycle of Tesa/Ipa during the 6 months on FLGR242. In the middle of an 8 week cycle of SS-31/Mots-c/NAD+/5Amino-1mq.

                  Any advice from PeptidePete, Stones67 or Diegoc on anything you would recommend I do differently I would appreciate it. Will keep you all updated. PeptidePete and Stones67 sold me on trying FLGR242 after reading about their results.

                  S S D 3 Replies Last reply
                  0
                  • D denti

                    Ordered 12 vials and will do a 6 month period on FLGR242. Will follow the protocol Stones67 posted above. Here are my starting stats. Just had Dexa and labs done again last week. Will get them again after 12 weeks of FLGR242 and resistance training and again at the end of 24 weeks

                    Male 44
                    Weight 165.2lbs (Weighed 162 that morning on my own scale without clothing and 159lbs today)
                    Body Fat: 18.8%
                    Body Fat: 31 lbs
                    Lean Mass: 127.1 lbs
                    Visceral Fat: 0.60 lbs

                    Testosterone: 513
                    Testosterone Free (Dialysis) 73.6
                    T4 Free: 1.3
                    T3 Free: 2.9
                    IGF 1: 193
                    Z Score: 0.7
                    SHBG: 41

                    Currently no resistance training, but a lot of running with a weighted vest. Will cut down on running and focus mainly resistance training on my Tonal as I feel like I look just soft and skinny fat. Would like to do a body recomposition. Will probably get back on a cycle of Tesa/Ipa during the 6 months on FLGR242. In the middle of an 8 week cycle of SS-31/Mots-c/NAD+/5Amino-1mq.

                    Any advice from PeptidePete, Stones67 or Diegoc on anything you would recommend I do differently I would appreciate it. Will keep you all updated. PeptidePete and Stones67 sold me on trying FLGR242 after reading about their results.

                    S Offline
                    S Offline
                    Shaqdiesel
                    wrote last edited by
                    #163

                    @denti I know this is off the topic here so maybe a DM but can you tell me the specifics for your 8-week protocol for SS-31/Mots-c/NAD+/5Amino-1mq? How much, when, frequency for each? Results so far?

                    D 1 Reply Last reply
                    0
                    • D denti

                      Ordered 12 vials and will do a 6 month period on FLGR242. Will follow the protocol Stones67 posted above. Here are my starting stats. Just had Dexa and labs done again last week. Will get them again after 12 weeks of FLGR242 and resistance training and again at the end of 24 weeks

                      Male 44
                      Weight 165.2lbs (Weighed 162 that morning on my own scale without clothing and 159lbs today)
                      Body Fat: 18.8%
                      Body Fat: 31 lbs
                      Lean Mass: 127.1 lbs
                      Visceral Fat: 0.60 lbs

                      Testosterone: 513
                      Testosterone Free (Dialysis) 73.6
                      T4 Free: 1.3
                      T3 Free: 2.9
                      IGF 1: 193
                      Z Score: 0.7
                      SHBG: 41

                      Currently no resistance training, but a lot of running with a weighted vest. Will cut down on running and focus mainly resistance training on my Tonal as I feel like I look just soft and skinny fat. Would like to do a body recomposition. Will probably get back on a cycle of Tesa/Ipa during the 6 months on FLGR242. In the middle of an 8 week cycle of SS-31/Mots-c/NAD+/5Amino-1mq.

                      Any advice from PeptidePete, Stones67 or Diegoc on anything you would recommend I do differently I would appreciate it. Will keep you all updated. PeptidePete and Stones67 sold me on trying FLGR242 after reading about their results.

                      S Offline
                      S Offline
                      Stones67
                      wrote last edited by
                      #164

                      @denti
                      Grade-A. Well thought out analysis and plan. Your labs look good. Ideally a bit more T would be nice but as you trim away some more BF you may. see a bump. Awesome you just had a Dexa. I started FLGR about 2 months after my first Dexa so my second testing results were after 4 months of using. Wish I would have timed this better but such is life. Currently I'm 'blasting' at 5mg weekly (1mg daily Tues-Sat) which BLL considers 'advanced' use. There is no scientific reason for this dosing strategy and I can't dispute those who say weekly or twice a week dosing is the way to go. In roughly 2 months I plan on a break and am currently trying to decide what, if anything, to substitute with (ex. IGF1-LR3 + PEG MGF for 6 weeks- thoughts Pete, Diego, and Co?). Others will chime in I'm sure but I would emphasize Tonal 3-5 times a week (flgr is a muscle building compound after all) and increase protein to 1.5-1.8 gm lean body mass daily. Welcome to the club lab rat!

                      D 1 Reply Last reply
                      1
                      • vpepsV Online
                        vpepsV Online
                        vpeps
                        wrote last edited by
                        #165

                        I wonder if anybody has formed an opinion on their alphaKlothoLR individually. I learned about Klotho protein and Klotho peptides, that it's considered having a promising rejuvenating effect on many body systems, and might try it. This one is bound to albumin and should stay in the system over 2-week period. Does anybody have an experience using it, especially without FLGR242? I am not sure if I even need Follistatin, but Klotho is interesting.

                        attentiion is all you need

                        1 Reply Last reply
                        0
                        • ResearchCatR Offline
                          ResearchCatR Offline
                          ResearchCat
                          wrote last edited by
                          #166

                          @stones67 Yep, the deeper I get into this area, the more it is underscored that you need the foundation to be solid. If you are not exercising, and specifically lifting heavy things, your results will be limited. Same with getting protein, getting your T levels and labs right, etc.

                          Yeah, well, I’m just here for the research, man. - The Dude

                          If I haven’t liked your post, no offense. I have exceeded my daily allowance.

                          D 1 Reply Last reply
                          0
                          • ResearchCatR ResearchCat

                            @stones67 Yep, the deeper I get into this area, the more it is underscored that you need the foundation to be solid. If you are not exercising, and specifically lifting heavy things, your results will be limited. Same with getting protein, getting your T levels and labs right, etc.

                            D Offline
                            D Offline
                            diegoc
                            wrote last edited by
                            #167

                            @ResearchCat well thats 100%, peptides are just tools to the foundation. Hormones including Thyroid, IGF, Testosterone.

                            Then everything works like clockwork

                            S 1 Reply Last reply
                            1
                            • ResearchCatR Offline
                              ResearchCatR Offline
                              ResearchCat
                              wrote last edited by
                              #168

                              Yessir, I just think it bears repeating and repeating again. I know a few people both here and IRL who are using peptides and/or GLP-1’s (mainly GLP-1’s) and aren’t doing any of the other stuff and aren’t getting optimal results. I am just starting to look at enclomiphene/TRT because I have been reading more about what ‘normal’ is and what the realities are about it. I have gotten good results with peps, but have not been able to build muscle. I am maintaining, but not gaining. Might be T levels, might just be me.

                              I look and feel great, but still need to check that one thing - which underlies all the rest.

                              Yeah, well, I’m just here for the research, man. - The Dude

                              If I haven’t liked your post, no offense. I have exceeded my daily allowance.

                              1 Reply Last reply
                              1
                              • D diegoc

                                @ResearchCat well thats 100%, peptides are just tools to the foundation. Hormones including Thyroid, IGF, Testosterone.

                                Then everything works like clockwork

                                S Offline
                                S Offline
                                Stones67
                                wrote last edited by
                                #169

                                @diegoc
                                Weren't you running Klotho, without FLGR?

                                D 1 Reply Last reply
                                0
                                • S Stones67

                                  @diegoc
                                  Weren't you running Klotho, without FLGR?

                                  D Offline
                                  D Offline
                                  diegoc
                                  wrote last edited by
                                  #170

                                  @Stones67 Yeah ive only taken Klotho and I have had great results.

                                  Im leaving FLGR for January when i start my lean bulk.

                                  vpepsV 1 Reply Last reply
                                  1
                                  • D Offline
                                    D Offline
                                    diegoc
                                    wrote last edited by
                                    #171

                                    When i mean great results are dialing in everything I wrote in the previous text

                                    1 Reply Last reply
                                    1
                                    • D diegoc

                                      @Stones67 Yeah ive only taken Klotho and I have had great results.

                                      Im leaving FLGR for January when i start my lean bulk.

                                      vpepsV Online
                                      vpepsV Online
                                      vpeps
                                      wrote last edited by
                                      #172

                                      @diegoc do you mean you can pinpoint at the difference between with Klotho LR and without it, that can't be attributed to something else?

                                      attentiion is all you need

                                      D 1 Reply Last reply
                                      0
                                      • S Shaqdiesel

                                        @denti I know this is off the topic here so maybe a DM but can you tell me the specifics for your 8-week protocol for SS-31/Mots-c/NAD+/5Amino-1mq? How much, when, frequency for each? Results so far?

                                        D Offline
                                        D Offline
                                        denti
                                        wrote last edited by denti
                                        #173

                                        @Shaqdiesel said:

                                        @denti I know this is off the topic here so maybe a DM but can you tell me the specifics for your 8-week protocol for SS-31/Mots-c/NAD+/5Amino-1mq? How much, when, frequency for each? Results so far?

                                        Sure. This is my first time running this stack so I am not saying follow this but this is what I decided to do after researching what others have done, what they stacked and when.

                                        SS-31: Weeks 1-8/Daily 10mg
                                        Mots-c: Weeks 5-8/ Mon,Wed,Fri 2mg first week titrating up to 5mg final 2 weeks
                                        NAD+: Weeks 5-8/ Tue,Thurs Sat 25mg first week titrating up to 100mg final weeks
                                        5AM1MQ: Weeks 5-12/Daily 5mg (This one I have ran before with Tesa and like it)

                                        Results. I started my peptide journey about 4months ago. I started around 190lbs back in February/March. Goal was to get down to 175. Then still felt fat so new goal was 160lbs which I am past. I have ran Wolverine stack for 8 weeks for knee and achilles pain and healed my achilles. Ran 5AM1MQ for 8 weeks and also ran Tesa without ipa for 8 weeks and my visceral fat according to dexa back in February was 1.2lbs. Last week after dexa it was 0.6lbs. So I believe that definitely helped. I'm finishing up final few days of AOD-9064. I take that fasted in the morning. Does that help I really don't know. My problem is I have tried so many different peptides for 8 weeks cycle one on top of another and I have just continued to cut weight. So what's really working the best I cannot pinpoint. And then I also physically run a lot so that could really be what's helping me lose weight. That's the unfortunate part of running too many things all at once.

                                        My issue is that I have been losing weight slowly for the past 4 years. I started around 260lb. So I lost 70lbs on my own without the use of any peptides but these last 4 months on peptides with increase in cardio has made the weight fall off much faster. So I can't really pinpoint to what worked best and just trying things out as I go along. So with this SS-31/Mots-c/NAD+/5AM1MQ my goal was to push my endurance even harder. I can run 6miles with a 40lb weighted vest on me. I wanted to push further and see what my limits are physically. I feel more energetic with this stack but could be placebo. It's an expensive stack to run with SS-31 but I am willing to try everything once.

                                        I hate the way I look. I just look skinny fat and soft (I think due to having so much loose skin otherwise everyone who sees me clothed thinks I look very lean) and that's why I am now going to switch it up after this SS31/motsc/nad cycle is done and focus on FLGR242 and resistance training. It's like what PeptidePete wrote above in this thread about body recomposition. I made losing lbs on the scale my focus and I'm actually not happy the way I look even though the scale has me below what my goal was. I rather be 175lbs and lean and cut then 155lbs and soft. Its a hard mental transition to make as I feel bad every time I weigh myself and the scale goes up even 1lb but logically I know its about how you look that matters, not the number on the scale. I'm 44 and would like to have visible abs for once in my life even if I can't maintain it. But unfortunately I have too much excess skin that I will probably need to have surgery one day to remove it. But for now I can try to bulk up with muscle and try to get below 15% body fat with the help of FLGR242.

                                        I should add back in February when I had a dexa right before starting peptides, I had nearly 30% body fat. So in the 4months It has dropped around 12%

                                        D 1 Reply Last reply
                                        0
                                        • D denti

                                          @Shaqdiesel said:

                                          @denti I know this is off the topic here so maybe a DM but can you tell me the specifics for your 8-week protocol for SS-31/Mots-c/NAD+/5Amino-1mq? How much, when, frequency for each? Results so far?

                                          Sure. This is my first time running this stack so I am not saying follow this but this is what I decided to do after researching what others have done, what they stacked and when.

                                          SS-31: Weeks 1-8/Daily 10mg
                                          Mots-c: Weeks 5-8/ Mon,Wed,Fri 2mg first week titrating up to 5mg final 2 weeks
                                          NAD+: Weeks 5-8/ Tue,Thurs Sat 25mg first week titrating up to 100mg final weeks
                                          5AM1MQ: Weeks 5-12/Daily 5mg (This one I have ran before with Tesa and like it)

                                          Results. I started my peptide journey about 4months ago. I started around 190lbs back in February/March. Goal was to get down to 175. Then still felt fat so new goal was 160lbs which I am past. I have ran Wolverine stack for 8 weeks for knee and achilles pain and healed my achilles. Ran 5AM1MQ for 8 weeks and also ran Tesa without ipa for 8 weeks and my visceral fat according to dexa back in February was 1.2lbs. Last week after dexa it was 0.6lbs. So I believe that definitely helped. I'm finishing up final few days of AOD-9064. I take that fasted in the morning. Does that help I really don't know. My problem is I have tried so many different peptides for 8 weeks cycle one on top of another and I have just continued to cut weight. So what's really working the best I cannot pinpoint. And then I also physically run a lot so that could really be what's helping me lose weight. That's the unfortunate part of running too many things all at once.

                                          My issue is that I have been losing weight slowly for the past 4 years. I started around 260lb. So I lost 70lbs on my own without the use of any peptides but these last 4 months on peptides with increase in cardio has made the weight fall off much faster. So I can't really pinpoint to what worked best and just trying things out as I go along. So with this SS-31/Mots-c/NAD+/5AM1MQ my goal was to push my endurance even harder. I can run 6miles with a 40lb weighted vest on me. I wanted to push further and see what my limits are physically. I feel more energetic with this stack but could be placebo. It's an expensive stack to run with SS-31 but I am willing to try everything once.

                                          I hate the way I look. I just look skinny fat and soft (I think due to having so much loose skin otherwise everyone who sees me clothed thinks I look very lean) and that's why I am now going to switch it up after this SS31/motsc/nad cycle is done and focus on FLGR242 and resistance training. It's like what PeptidePete wrote above in this thread about body recomposition. I made losing lbs on the scale my focus and I'm actually not happy the way I look even though the scale has me below what my goal was. I rather be 175lbs and lean and cut then 155lbs and soft. Its a hard mental transition to make as I feel bad every time I weigh myself and the scale goes up even 1lb but logically I know its about how you look that matters, not the number on the scale. I'm 44 and would like to have visible abs for once in my life even if I can't maintain it. But unfortunately I have too much excess skin that I will probably need to have surgery one day to remove it. But for now I can try to bulk up with muscle and try to get below 15% body fat with the help of FLGR242.

                                          I should add back in February when I had a dexa right before starting peptides, I had nearly 30% body fat. So in the 4months It has dropped around 12%

                                          D Offline
                                          D Offline
                                          diegoc
                                          wrote last edited by diegoc
                                          #174
                                          This post is deleted!
                                          1 Reply Last reply
                                          0

                                          Hello! It looks like you're interested in this conversation, but you don't have an account yet.

                                          Getting fed up of having to scroll through the same posts each visit? When you register for an account, you'll always come back to exactly where you were before, and choose to be notified of new replies (either via email, or push notification). You'll also be able to save bookmarks and upvote posts to show your appreciation to other community members.

                                          With your input, this post could be even better 💗

                                          Register Login
                                          Reply
                                          • Reply as topic
                                          Log in to reply
                                          • Oldest to Newest
                                          • Newest to Oldest
                                          • Most Votes


                                          • Login

                                          • Login or register to search.
                                          • First post
                                            Last post
                                          0
                                          • Categories
                                          • Recent
                                          • Tags
                                          • Popular
                                          • World
                                          • Users
                                          • Groups