Klotho / FLGR242 (albumin-bound new tech)
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@tbone If memory serves... Josh Holyfield was speaking about FLGR242, not Klotho. Just want to make sure I didn't miss some detail. Klotho is more interesting to me right now than FLGR242, because most of the things I'm interested in athletically require strength to weight ratio, so I'm not hugely interested in packing on muscle... more building up strength and maintaining a light (but healthy) muscle mass
@tbone If memory serves... Josh Holyfield was speaking about FLGR242, not Klotho. Just want to make sure I didn't miss some detail. Klotho is more interesting to me right now than FLGR242, because most of the things I'm interested in athletically require strength to weight ratio, so I'm not hugely interested in packing on muscle... more building up strength and maintaining a light (but healthy) muscle mass
Klotho is very subtle. I believe I noticed it, I believe it had and has noticeable benefits, and I believe like flgr242 it's something that you need to plan on using until something better comes along and that may be years from now . It's not a one hit wonder, it's not you do one or two vials and then you're one and done . If you're older and you're deficient that's just the fact of the matter and you're going to be using it until the day you die or something else comes along . That's my personal opinion of course but it's also backed up by science in regards to age deficiency. It's anecdotal and not 100% direct but I do have frequent Labs run, kidney function is perfect and I do some other materials that are somewhat stressful on the physiology
so that's somewhat of a objective measure. I also use cystatin C as my testing not the usual egfr which if you're using creatine at higher levels as I am can affect regular egFR. So be a careful and smart researcher. Bottom line I'm still on it and I plan to be on it as I said , it's not something that you want to cycle it makes no sense to do so. Hope that helps 
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@tbone If memory serves... Josh Holyfield was speaking about FLGR242, not Klotho. Just want to make sure I didn't miss some detail. Klotho is more interesting to me right now than FLGR242, because most of the things I'm interested in athletically require strength to weight ratio, so I'm not hugely interested in packing on muscle... more building up strength and maintaining a light (but healthy) muscle mass
@PeptideEd his most recent video basicly boils down to saying it inhibits one of two factors needed for that ridiculous rat study to track with humans. Which it misses out on activin a reduction? My response in my mind was. So stack ace031 and flgr242? Sorted
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@PeptideEd his most recent video basicly boils down to saying it inhibits one of two factors needed for that ridiculous rat study to track with humans. Which it misses out on activin a reduction? My response in my mind was. So stack ace031 and flgr242? Sorted
@PeptideEd his most recent video basicly boils down to saying it inhibits one of two factors needed for that ridiculous rat study to track with humans. Which it misses out on activin a reduction? My response in my mind was. So stack ace031 and flgr242? Sorted
Thank you for posting with those comments, as I didn't see that video or what this guy said. See this is the problem there is so much b******* out there promulgated by people who were conflicted. It just pisses me off because you can't trust anybody, especially people doing YouTube videos because there's maybe 1% of people who are not conflicted and therefore giving you bad information. It really pisses me off.
Flgr242 in arguably incontestably works. End of story I don't give a f*** what somebody's guesses and ideas are, I know what it did for me and it did things that nothing else in my life ever did for me with zero negative side effects. If you're an older person and you want to counter the effects of sarcopenia in combination with a proper lifestyle, for me no sugar no carbs no vegetables and a pretty strict carnivore diet, the myostatin inhibitor is absolute pure Magic . This Josh fellow can go screw himself with his b******* . I got zero patience for this crap.
A side note I just thought about, I had a tumor in one of my sinuses that I had to have radiation treatment on 3 years ago because it was not accessible for surgery without actually cutting bone out , and I wasn't going to do that. I just had a three and a half year follow up with my radiation oncologist to review my latest MRI. This is subsequent to using the flgr 242 and being on growth hormone and a variety of other fun and interesting peptides, the tumor is completely gone no regrowth and my radiation oncologist was tickled pink with how I looked, said I looked jacked . I assure you never in my life has anybody told me I ever looked jacked
that was 100% flgr242 , because I never looked jacked from simply being on Carnivore for three and a half years . There's a data point that anyone that wants to can put in their pipe and smoke it 
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@PeptideEd his most recent video basicly boils down to saying it inhibits one of two factors needed for that ridiculous rat study to track with humans. Which it misses out on activin a reduction? My response in my mind was. So stack ace031 and flgr242? Sorted
Thank you for posting with those comments, as I didn't see that video or what this guy said. See this is the problem there is so much b******* out there promulgated by people who were conflicted. It just pisses me off because you can't trust anybody, especially people doing YouTube videos because there's maybe 1% of people who are not conflicted and therefore giving you bad information. It really pisses me off.
Flgr242 in arguably incontestably works. End of story I don't give a f*** what somebody's guesses and ideas are, I know what it did for me and it did things that nothing else in my life ever did for me with zero negative side effects. If you're an older person and you want to counter the effects of sarcopenia in combination with a proper lifestyle, for me no sugar no carbs no vegetables and a pretty strict carnivore diet, the myostatin inhibitor is absolute pure Magic . This Josh fellow can go screw himself with his b******* . I got zero patience for this crap.
A side note I just thought about, I had a tumor in one of my sinuses that I had to have radiation treatment on 3 years ago because it was not accessible for surgery without actually cutting bone out , and I wasn't going to do that. I just had a three and a half year follow up with my radiation oncologist to review my latest MRI. This is subsequent to using the flgr 242 and being on growth hormone and a variety of other fun and interesting peptides, the tumor is completely gone no regrowth and my radiation oncologist was tickled pink with how I looked, said I looked jacked . I assure you never in my life has anybody told me I ever looked jacked that was 100% flgr242 , because I never looked jacked from simply being on Carnivore for three and a half years . There's a data point that anyone that wants to can put in their pipe and smoke it @PeptidePete eh i would watch the video. Hes not exactly greg doucette rage baiting it. Hes just saying theres not enough information or positive studies to 100 percent confirm or deny the effects. Its so new i kinda agree in that regard. I mean 10 to 15 years ago i remember most of the guys my age saw growth hormone like witchcraft. Now fast forward every balding gym bro is pushing 2 to 5u like its b12 or something. Just needs time like every other new drug.
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@PeptidePete eh i would watch the video. Hes not exactly greg doucette rage baiting it. Hes just saying theres not enough information or positive studies to 100 percent confirm or deny the effects. Its so new i kinda agree in that regard. I mean 10 to 15 years ago i remember most of the guys my age saw growth hormone like witchcraft. Now fast forward every balding gym bro is pushing 2 to 5u like its b12 or something. Just needs time like every other new drug.
@PeptidePete eh i would watch the video. Hes not exactly greg doucette rage baiting it. Hes just saying theres not enough information or positive studies to 100 percent confirm or deny the effects. Its so new i kinda agree in that regard. I mean 10 to 15 years ago i remember most of the guys my age saw growth hormone like witchcraft. Now fast forward every balding gym bro is pushing 2 to 5u like its b12 or something. Just needs time like every other new drug.
My n = 1 and diligent and deep regular testing is all the information I need. Thanks for the additional info on the video I may actually have this guy blocked on youtube, I'll have to look him up and watch it and see what he has to say. I have nothing to sell to anybody except for truth and the strongest possible suggestion that anyone form their opinions based on nothing other than their own research. It seems like everything except for the tiniest percent is nothing more than propaganda or a psyop
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I'm another N=1. I'm 59yo. I'm exactly at 3 months since starting FLGR (no Klotho) and without a doubt have recorded visible changes in my physique that would not have occurred without running gear. Labs done after a month were all improved (fasted glucose, A1c, etc) but at the time was also running reta at 0.5mg every 6 days. Next labs in about a month and I may not be able to stop myself from adding a repeat Dexa (my curiosity is getting the better of me). I believe it (flgr) is allowing me to move beyond my myostatin regulated genetic potential. My testosterone is optimized with enclomiphene and I enjoy CJC/Ipa. The grey hair not withstanding, I look and feel closer to 40. But this is a speculative play. Not in terms of results, as I can honestly vouch for those now, but in terms of safety. I have enough stocked away for another year but am considering running this for another 3 months or so, and then taking a few months off. I'm honestly curious about the durability of results. I think Pete will still be on the stuff when he croaks at 150! Only buy when on sale (I don't buy anything else on BLL cuz all their stuff is crazy expensive) but shoot for at least 6 months. I wouldn't be surprised if they do something enticing over the 4th. Someone else is going to eventually reverse engineer the albumin binder part or figure out another way to extend half-life. The monoclonal antibody stuff is intriguing and I'll take my cues from quicksilver as he formulates his thoughts over time. Or go to Panama or the Bahamas or wherever and have your genes altered! Otherwise it's PED's or FLGR as far as I can tell! I watch Josh H. and think he does OK making AI research sound like his own. Unfortunately there is no real research on this new stuff so unless he tries it for 6 months he really doesn't know anything. Hope that helps and happy to chime in anytime!
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I just watched the video that's 15 minutes of my life I'll never get back. Look here's the bottom line I'm not going to waste any time on this if you're researching this material and you do not clearly understand the four different follistatins being discussed then you don't know what you're doing and you need to do better homework. Number one gene therapy number two monoclonal antibody number 3 injected directly into the muscle number four flgr242 albumin bound. Four completely different conversations if you don't understand that you need to dig deeper. This video was a pile of garbage and struck me as nothing more than hit piece and an attempt to appear intelligent when in fact he made himself out to be absolutely ignorant on the topic at hand. Let me be crystal clear I have an extremely hard time stomaching Jay Campbell I'm no sycophant for bio longevity labs . I'm a researcher I'm a serious researcher and I care about what works and what has minimum or no side effects. If you're looking if you're looking at this material dig deep. I'm not a gym rat, I'm not a bodybuilder, I have no tattoos I have no piercings and I'm sure as f*** not selling coaching. An absolute perfect example this video is of buyer beware and taking the time and making the effort to understand what it is that you're talking about.
Ps- I'm doing all of my post today using voice dictation on my phone so they're formatted like I'm a moron
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Stones 67, thank you for your post very interesting! Nothing in my previous post was oriented towards you whatsoever just to be clear on that. I appreciate you sharing your journey and your personal viewpoints it's helpful to everyone and I very much enjoy reading your post
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Yeah i also dont take any of this personally. Just having a interesting conversation with stuff weve all seen that may or may not argue the opposing side. Thats kinda how i research. I dont look at it as how is he wrong but where are the holes in my ideas. Guess doing that to other peoples videos can be seen as strange though hopefully noone took me as antagonistic or inflammatory
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Stones 67, thank you for your post very interesting! Nothing in my previous post was oriented towards you whatsoever just to be clear on that. I appreciate you sharing your journey and your personal viewpoints it's helpful to everyone and I very much enjoy reading your post
@PeptidePete Didn't even cross my mind that you were speaking to me directly. We are all good. I like this topic and greatly enjoy the discourse! Glad there's a couple folks on here either already well along in their journey or doing a deep dive to see if it sounds right for them. I can tell you know your s**t. I value your insights (and quicks!) and read your comments with interest.
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Thought of some strings I'd highly recommend curious folks to pull on:
- The gene therapies for all their promise seem to have not worked well. Poor results. Both minicircle and plasmid.
- As always happens grifters are identified- Adeel Khan (no surprise).
- The inventor of FLGR242 and a-Klotho MAB, Mike Farber, is worthy of a deep dive, I like everything I see and hear.
- My wife (petite) has been on FLGR for 4 months now at 2mg once per week and she has gone from having ZERO desire for variable resistance workouts to being a little workout monster and looks great.
- The monoclonal antibodies aside from being simply unattainable have in most cases quite serious unwanted side effects.
I thank my lucky stars I immediately recognized the value on offer when the two MAB (Modified Albumin Binding) agents were introduced by BLL last year, Mike Farber is in the same situation I am, aging and wanting some good, REAL, solutions. He eats his own cooking. I'm so thankful he is who he is. That's all for me for a while because I sound like a paid shill, but I am a PAYING shill...lol. Dig deep my friends, trust no one. And never ever forget when you are reading or watching something, "THEY" want you weak and compliant, I'm shocked FLGR/a-Klotho can still be bought. Do your homework, be the absolute best you can be.
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I am going to vote this thread the most expensive thread in peptide history. Congratulations on wiping out all my savings since joining this forum.
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I am going to vote this thread the most expensive thread in peptide history. Congratulations on wiping out all my savings since joining this forum.
I am going to vote this thread the most expensive thread in peptide history. Congratulations on wiping out all my savings since joining this forum.
My SS-31/Sturgeon roe posts perhaps come in at #2?
LOL
The price of vigor and vascularity!
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This is interesting, but both users in this thread have confounding compounds and may be more motivated at the gym by placebo effect. Would love to see graphs from stats, labs and workout trackers to see if you are beating what would be considered normal gains.
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@peptideed speaking of your sturgeon roe posts… could you expand on (or at least point out the threads to pull) the reason sturgeon roe instead of sockeye salmon roe?
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@peptideed speaking of your sturgeon roe posts… could you expand on (or at least point out the threads to pull) the reason sturgeon roe instead of sockeye salmon roe?
@peptideed speaking of your sturgeon roe posts… could you expand on (or at least point out the threads to pull) the reason sturgeon roe instead of sockeye salmon roe?
As noted in the other thread, I urge independent research on this topic. Very different nutrient profiles.
The salmon roe is the next best choice but you need to be accepting of a very different flavor profile as well. If salmon, I'd suggest buying the fresh-frozen ones and defrosting as needed. Some of the stuff in jars is vile, you eat oxidized roe you are damaging your body.
My new favorite supplier, Bester Caviar, just ran a buy two get two sale (that's 50% off for math challenged...lol) for 24 hours. Bought several kgs enough for several months.
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I am going to vote this thread the most expensive thread in peptide history. Congratulations on wiping out all my savings since joining this forum.
@ResearchCat I’ll second that vote! lol
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This is interesting, but both users in this thread have confounding compounds and may be more motivated at the gym by placebo effect. Would love to see graphs from stats, labs and workout trackers to see if you are beating what would be considered normal gains.
@vonendorphin "Both users" cracked me up! Thank you! Of course you are correct about confounding factors. What phrase is usually at the end of almost every medical study?- "more research is needed to explain blah, blah, blah". I'm an N=1. 30 years ago I used to track stuff like that when I was doing triathlons. But that dog don't hunt no more. I will say my stack is stable with the only major change being no reta for the last month when I felt it was holding back gains. I have used the Tonal system exclusively for resistance training for the last 4 and a half years and made solid gains the old fashioned way- ie dad bod and no peps. It has something called a strength score which I follow with marginal interest. I'll see if I can figure out how to pull a screen shot of the last six months and post it- but I'm an old fart who is constantly several steps behind in tech. To save you the suspense it would show my score falling off a cliff mid February due to a small rotator cuff tear and a nasty case of impingement. Rehab. Started back slow and steady while avoiding certain lifts not endorsed by my ortho colleagues. Finally feeling confident enough in my shoulder to start pushing it again. But what I see, during a period of forced reduced effort, has still impressed me, which I attribute to FLGR. The missus is impressed enough she's gonna start the women's version called 'slim assist' so we'll maybe have some N=2 data in a few months! Our moto has been we have to either see it or feel it or it goes to the back of the line.
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@Stones67 any weird side effects worth note? I feel like they'd be similar to gh
@Stones67 any weird side effects worth note? I feel like they'd be similar to gh
No FLGR negative sides whatsoever. None. Not AT ALL like GH.
Positives- The vascularity (unmistakable), craving workouts once this stuff kicks in over time and at higher doses (1mg/day). The ramp-up of those effects lasted for approx 6-8 weeks and tapered away as I packed on the skeletal muscle mass.
Side note for those on a GLP- YOU HAVE TO EAT PROTEIN (not garbage crap) and lots of it for this to generate a supercharging effect on lean mass. I would suggest Jaquish Biomedical Fortagen 2x daily + the biggest fatty ribeye(s) you can cram down. And roe, lots of roe
GH over 4-6IU I get the darn mitten-hands and clown-shoe feet
Otherwise I'd run 10 IU of the stuff. It's so cheap nowadays for pharma-grade+.
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