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Peptide Critic Community

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  1. Randy the Rats Research Forum
  2. Peptide Discussion
  3. Mots-c and SS-31
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Mots-c and SS-31

Scheduled Pinned Locked Moved Peptide Discussion
mots-cresearchingss-31
51 Posts 18 Posters 3.0k Views 5 Watching
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  • N nosaj

    Looking for opinions on how necessary it is to run SS-31 before Mots-c. Ready to add Mots to my stack tomorrow and second guessing myself with all the talk about SS-31. Would it hurt to try the Mots first? I have a generally low carb diet and have intermittent fasted for years. Already have the Mots and adding to CJC/Ipa, Reta
    Thanks guys

    W Offline
    W Offline
    [email protected]
    wrote on last edited by
    #17

    @nosaj said in Mots-c and SS-31:

    Looking for opinions on how necessary it is to run SS-31 before Mots-c. Ready to add Mots to my stack tomorrow and second guessing myself with all the talk about SS-31. Would it hurt to try the Mots first? I have a generally low carb diet and have intermittent fasted for years. Already have the Mots and adding to CJC/Ipa, Reta
    Thanks guys

    1 Reply Last reply
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    • J Online
      J Online
      jackiew1
      wrote on last edited by
      #18

      Not sure, but I ran MOTS-c for almost 12 weeks and I have never run SS-31.

      1 Reply Last reply
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      • R Online
        R Online
        ResearchCat
        wrote on last edited by
        #19

        If you don’t have significant metabolism dysfunction, you probably don’t need SS-31 beforehand.

        100% Natty. You know, aside from the Klow, Tesa, Tirz, CJC/Ipa, SS-31, Semax, Dihexa, Epitalon, MOTS-C, creatine, Cheetos, protein shakes, and a holocaust of chicken thighs.

        quicksilver80Q gym.ratG 2 Replies Last reply
        1
        • R ResearchCat

          If you don’t have significant metabolism dysfunction, you probably don’t need SS-31 beforehand.

          quicksilver80Q Online
          quicksilver80Q Online
          quicksilver80
          wrote on last edited by
          #20

          @ResearchCat the way i see it is if alot of us were heavy to begin with. its not like our metabolism was doing good in the first place. im not seeing any serious side effects. worth a try.

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          • R ResearchCat

            If you don’t have significant metabolism dysfunction, you probably don’t need SS-31 beforehand.

            gym.ratG Offline
            gym.ratG Offline
            gym.rat
            wrote on last edited by
            #21

            @ResearchCat I think any rats over 40 have mito dysfunction or at least I would think. SS-31 is a short protocol anyway so I would do this before MOTS for sure. You can keep taking NAD+ along side it from what I have read.

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            • Stan DouglasS Stan Douglas

              @gym.rat
              I'm at 8 today:
              Pre-workout: Mots & AOD
              Post workout; CJC[No Dac]+ Ipam
              Afternoon: 2nd CJC+
              Bedtime: Last CJC+, Pine and 2 Ghks

              and it's not even a NAD+ day.

              I would had bought stock in .3 syringes at the beginning of this hobby had I known I'd be going through so many.

              kenhnsyK Offline
              kenhnsyK Offline
              kenhnsy
              wrote on last edited by
              #22

              @Stan-Douglas said in Mots-c and SS-31:

              I'm at 8 today:

              I'm about to cycle back on and count 12 filled pens in the refrigerator. 2 more coming up. Freaks. All of you.

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              • R Online
                R Online
                ResearchCat
                wrote on last edited by
                #23

                @gym.rat @quicksilver80 Yeah, I am by no means the authority. A lot of us tend to do all of the things, and it’s hard to assume we either do or do not need on particular thing. I am willing to bet that researching MOTS-C by itself will be effective, but also that running the mechanic stack (SS-31, MOTS-C, NAD+) will also be effective. I don’t know how old or healthy people are, and while I often assume the young folks are in better shape than me, I have been made aware that a lot of young guys’ metabolisms are messed up for a variety of reasons.

                As the saying goes, “that’s why they call it research.”

                My standard disclaimer is that I am focused on longevity and healthspan, so I won’t know if any of it is working until I’m dead.

                100% Natty. You know, aside from the Klow, Tesa, Tirz, CJC/Ipa, SS-31, Semax, Dihexa, Epitalon, MOTS-C, creatine, Cheetos, protein shakes, and a holocaust of chicken thighs.

                1 Reply Last reply
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                • J jackiew1

                  @commander , how long have you been doing Mt-2 three times per week? I did MT-1 for 10 days straight and I got the best tan! It is dark and such a nice color. It's been 3 weeks and I have hardly lost any of it and I haven't pinned it since.

                  I currently take two: GHK-cu twice daily and TA-1 twice weekly. I will cycle MOTS-c again in a few weeks.

                  My hubby is taking Reta twice weekly and Wolverine daily.

                  C Offline
                  C Offline
                  Commander
                  wrote on last edited by
                  #24

                  @jackie
                  Only a couple of weeks so far

                  Please excuse my typos. Small Phone & Bad Eyes

                  1 Reply Last reply
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                  • J Online
                    J Online
                    jackiew1
                    wrote on last edited by
                    #25

                    I got SO dark after 10 days on MT-1.

                    1 Reply Last reply
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                    • J Juan Doe

                      Isn’t it nad + that helps with mitochondria repair?

                      T Offline
                      T Offline
                      theckman80
                      wrote on last edited by
                      #26

                      @Juan-Doe NAD+ is what your mitochondria burn to make ATP. You can actually duel the salvage pathway with niacinamide (niacin) and your body turns it into nad+. Its a lot cheaper that way.

                      The ninja nerd guy on YouTube has some great videos on the Electron Transpot Chain/Cellular Respiration.

                      J gym.ratG 2 Replies Last reply
                      1
                      • T theckman80

                        @Juan-Doe NAD+ is what your mitochondria burn to make ATP. You can actually duel the salvage pathway with niacinamide (niacin) and your body turns it into nad+. Its a lot cheaper that way.

                        The ninja nerd guy on YouTube has some great videos on the Electron Transpot Chain/Cellular Respiration.

                        J Offline
                        J Offline
                        Juan Doe
                        wrote on last edited by
                        #27

                        @theckman80 Niacin. Just straight supplement? Sounds too simple to be true.

                        vpeptidesV 1 Reply Last reply
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                        • J Juan Doe

                          @theckman80 Niacin. Just straight supplement? Sounds too simple to be true.

                          vpeptidesV Online
                          vpeptidesV Online
                          vpeptides
                          wrote on last edited by
                          #28

                          @Juan-Doe Niacin works well to raise my NAD levels in cells. A 500 mg Niacin pill works a lot better than NMN or NR at higher doses as I tested. I did "Intracellular NAD" tests before and after, multiple times. And those NAD+ injections are virtually useless, except some transient feel-good (or bad for some) they don't raise NAD in the tissues.
                          Another story though is to ask whether we benefit from high NAD levels. I am not sure about it, probably not. But if you want them up, Niacin works the best.

                          J W 2 Replies Last reply
                          0
                          • T theckman80

                            @Juan-Doe NAD+ is what your mitochondria burn to make ATP. You can actually duel the salvage pathway with niacinamide (niacin) and your body turns it into nad+. Its a lot cheaper that way.

                            The ninja nerd guy on YouTube has some great videos on the Electron Transpot Chain/Cellular Respiration.

                            gym.ratG Offline
                            gym.ratG Offline
                            gym.rat
                            wrote on last edited by
                            #29

                            @theckman80 I totally agree with this. Can also add some NMN. One other fun piece of info is that niacinamide is awesome for arthritis.

                            T 1 Reply Last reply
                            2
                            • vpeptidesV vpeptides

                              @Juan-Doe Niacin works well to raise my NAD levels in cells. A 500 mg Niacin pill works a lot better than NMN or NR at higher doses as I tested. I did "Intracellular NAD" tests before and after, multiple times. And those NAD+ injections are virtually useless, except some transient feel-good (or bad for some) they don't raise NAD in the tissues.
                              Another story though is to ask whether we benefit from high NAD levels. I am not sure about it, probably not. But if you want them up, Niacin works the best.

                              J Offline
                              J Offline
                              Juan Doe
                              wrote on last edited by
                              #30

                              @vpeptides NMN or NR???? what are those?

                              @gym.rat Niacinamide? Vitamin B3? in what form? Cream, pill, injection?

                              My mind is going places right now because of this.

                              vpeptidesV gym.ratG 2 Replies Last reply
                              0
                              • J Juan Doe

                                @vpeptides NMN or NR???? what are those?

                                @gym.rat Niacinamide? Vitamin B3? in what form? Cream, pill, injection?

                                My mind is going places right now because of this.

                                vpeptidesV Online
                                vpeptidesV Online
                                vpeptides
                                wrote on last edited by
                                #31

                                @Juan-Doe those are NAD precursors, similar to Niacin but a lot more expensive, usually taken orally.

                                1 Reply Last reply
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                                • C Commander

                                  I take at least 4 a day. Now I am going to add SS-31 in.

                                  Mots-C
                                  NAD+
                                  KLOW
                                  Tesa/Ipa
                                  Reta 2/weekly
                                  MT2 3/weekly
                                  This would not be possible if it wasn’t for the Pens.
                                  Anyone not using Pens, I suggest you go over to the store section on here and buy at least 4 pens. If you only buy one pen, you will be back for more. So save on the shipping and just buy 4 from the start, it will save you money in the long run…

                                  I Offline
                                  I Offline
                                  iMemphis18
                                  wrote on last edited by
                                  #32

                                  @Commander out of curiosity, I don't disagree that its so much faster, but I feel like its a bit of a waste for certain peptides right?

                                  For example, Tesamorelin, 10 MG, with 1ML Bac water, i do 2mg -- which is 20 units. After about 4-5 days, i need to refill again, swap vials etc.

                                  or.... do people combine for example, 3 vials of Tesa, 10mg into the injection pen vial? This will def make each 3ML pen vial last longer. I am just curious on your thoughts. Been debating on $$ vs time saved. Especially since we need to buy the separate needle, then the 3 ML vial to go with the pen.

                                  C 1 Reply Last reply
                                  0
                                  • gym.ratG gym.rat

                                    @theckman80 I totally agree with this. Can also add some NMN. One other fun piece of info is that niacinamide is awesome for arthritis.

                                    T Offline
                                    T Offline
                                    theckman80
                                    wrote on last edited by
                                    #33

                                    @gym.rat I didn't know it had an effect on arthritis, ill have to get some for my brother.

                                    1 Reply Last reply
                                    0
                                    • I iMemphis18

                                      @Commander out of curiosity, I don't disagree that its so much faster, but I feel like its a bit of a waste for certain peptides right?

                                      For example, Tesamorelin, 10 MG, with 1ML Bac water, i do 2mg -- which is 20 units. After about 4-5 days, i need to refill again, swap vials etc.

                                      or.... do people combine for example, 3 vials of Tesa, 10mg into the injection pen vial? This will def make each 3ML pen vial last longer. I am just curious on your thoughts. Been debating on $$ vs time saved. Especially since we need to buy the separate needle, then the 3 ML vial to go with the pen.

                                      C Offline
                                      C Offline
                                      Commander
                                      wrote on last edited by
                                      #34

                                      @iMemphis18 said in Mots-c and SS-31:

                                      @Commander out of curiosity, I don't disagree that its so much faster, but I feel like its a bit of a waste for certain peptides right?

                                      For example, Tesamorelin, 10 MG, with 1ML Bac water, i do 2mg -- which is 20 units. After about 4-5 days, i need to refill again, swap vials etc.

                                      or.... do people combine for example, 3 vials of Tesa, 10mg into the injection pen vial? This will def make each 3ML pen vial last longer. I am just curious on your thoughts. Been debating on $$ vs time saved. Especially since we need to buy the separate needle, then the 3 ML vial to go with the pen.

                                      I put 3 vials of 10mg Tesa in the pen cart. That is how you save time.

                                      Please excuse my typos. Small Phone & Bad Eyes

                                      I 1 Reply Last reply
                                      2
                                      • vpeptidesV vpeptides

                                        @Juan-Doe Niacin works well to raise my NAD levels in cells. A 500 mg Niacin pill works a lot better than NMN or NR at higher doses as I tested. I did "Intracellular NAD" tests before and after, multiple times. And those NAD+ injections are virtually useless, except some transient feel-good (or bad for some) they don't raise NAD in the tissues.
                                        Another story though is to ask whether we benefit from high NAD levels. I am not sure about it, probably not. But if you want them up, Niacin works the best.

                                        W Offline
                                        W Offline
                                        WowwyZowwy
                                        wrote on last edited by
                                        #35

                                        @vpeptides Regarding NAD+ injections being "useless," any specific research that you can share on this? Anecdotally, the feedback within this community has been overwhelmingly positive (especially between the 50-100mg daily dosage. Could it really be all placebo effect? For context, what dosages were utilized in the studies you're referencing?

                                        vpeptidesV 1 Reply Last reply
                                        0
                                        • R Online
                                          R Online
                                          ResearchCat
                                          wrote on last edited by
                                          #36

                                          @commander running the same thing right now. The most I have stuffed into one cart is 7 vials of epitalon. I can only stuff 2 500mg NAD+ vials into one cart with 2.5ml bac water. A third will not dissolve (or fit.)

                                          100% Natty. You know, aside from the Klow, Tesa, Tirz, CJC/Ipa, SS-31, Semax, Dihexa, Epitalon, MOTS-C, creatine, Cheetos, protein shakes, and a holocaust of chicken thighs.

                                          C 1 Reply Last reply
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