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Tesamorelin Research Dosing Protocol

Scheduled Pinned Locked Moved Peptide Discussion
tesamorelinresearching
120 Posts 42 Posters 14.4k Views 4 Watching
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  • L lancerlot23

    I’ve been taking Tesamorelin for 2 weeks—1 mg during the first week and 2 mg at night during the second week. I inject it about 30 minutes before bed, with no food for at least 3 hours beforehand.
    Since starting it, my nighttime heart rate has increased. My average resting heart rate used to be around 60, but recently it’s been 86, 70, and 69. My stress levels have been very high, I’m not getting any REM sleep, and I’m having trouble sleeping overall.
    I know that this is an evening Peptide, but would AM hour work better maybe? I could pause for a couple of days and see if my heart rate and sleep normalize also.

    J Offline
    J Offline
    JtCjEfF
    wrote last edited by
    #71

    @lancerlot23 Any update on how this went? Researching Reta and Im +10 bpm, with the same negative results you mention. Last thing i need is more BPM's!

    1 Reply Last reply
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    • M Offline
      M Offline
      Macden
      wrote last edited by
      #72

      Great summary.
      One thing I would add is that monitoring IGF-1 during longer research protocols can be useful since individual responses vary. I also found this Tesamorelin research overview helpful for comparing dosing protocols and cycle lengths: https://peptidescostarica.net/tesamorelin-costa-rica/

      1 Reply Last reply
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      • WisGal64W Offline
        WisGal64W Offline
        WisGal64
        wrote last edited by
        #73

        @macden nice try lol. Joins 4 hours ago still promoting a site that contains fake coas

        “Not a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

        1 Reply Last reply
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        • S Offline
          S Offline
          Stones67
          wrote last edited by
          #74

          Hilarious. CR is a real hotbed for Tesa research! Does anyone know if they ship to the U.S.? lol

          1 Reply Last reply
          0
          • L lancerlot23

            I’ve been taking Tesamorelin for 2 weeks—1 mg during the first week and 2 mg at night during the second week. I inject it about 30 minutes before bed, with no food for at least 3 hours beforehand.
            Since starting it, my nighttime heart rate has increased. My average resting heart rate used to be around 60, but recently it’s been 86, 70, and 69. My stress levels have been very high, I’m not getting any REM sleep, and I’m having trouble sleeping overall.
            I know that this is an evening Peptide, but would AM hour work better maybe? I could pause for a couple of days and see if my heart rate and sleep normalize also.

            ratsoR Offline
            ratsoR Offline
            ratso
            wrote last edited by ratso
            #75

            @lancerlot23 probably should listen to your rat's body and lower the dose. that's a huge jump in heart rate.

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            • EXTROPIANE Offline
              EXTROPIANE Offline
              EXTROPIAN
              wrote last edited by EXTROPIAN
              #76

              I'm back on tesa. There was a reconstituted vial of tesa sitting in my kit. I didn't want to let it go to waste. Three days in now .500mcgs fasted over night.

              2M

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              • EXTROPIANE Offline
                EXTROPIANE Offline
                EXTROPIAN
                wrote last edited by EXTROPIAN
                #77

                So my metabolic stacks up like this now.
                Tesa 500mcgs-1mg daily
                Reta 2mg wkly
                5-amino 1mg, Slu-pp .500mcgs every other day
                Utilizing MOTSC 1-2mg NAD 10-20mg every other day from my mitochondrial stack.
                Wolverine, , epitholine, ss-31 and LL-37 1mg each every other day on the background for support, repair and immunity.
                All these stacks can be stacked different. They all support each the one way or another.

                2M

                S 1 Reply Last reply
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                • EXTROPIANE EXTROPIAN

                  So my metabolic stacks up like this now.
                  Tesa 500mcgs-1mg daily
                  Reta 2mg wkly
                  5-amino 1mg, Slu-pp .500mcgs every other day
                  Utilizing MOTSC 1-2mg NAD 10-20mg every other day from my mitochondrial stack.
                  Wolverine, , epitholine, ss-31 and LL-37 1mg each every other day on the background for support, repair and immunity.
                  All these stacks can be stacked different. They all support each the one way or another.

                  S Offline
                  S Offline
                  Stevepep
                  wrote last edited by
                  #78

                  @EXTROPIAN If you haven't tried Pinealon its worth trying for great sleep. I am just cycling off and going to try DSIP. My sleep scores are through the roof and they were horrible before I started

                  EXTROPIANE 1 Reply Last reply
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                  • S Stevepep

                    @EXTROPIAN If you haven't tried Pinealon its worth trying for great sleep. I am just cycling off and going to try DSIP. My sleep scores are through the roof and they were horrible before I started

                    EXTROPIANE Offline
                    EXTROPIANE Offline
                    EXTROPIAN
                    wrote last edited by EXTROPIAN
                    #79

                    @Stevepep Oh I'm sure it's good but I never had any trouble getting some good rest. I REM even in my naps. You set your phone alarm and just take notes. I wake up on time and all my agendas are notes. Just let go and sleep. Pineolon is in my Neuro future stack. Semax and Selank are doing me wonders right now.

                    2M

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                    • J Offline
                      J Offline
                      jimmy4407th
                      wrote last edited by
                      #80

                      I’ve run Tesa for 16 weeks while I was waiting for my HGH test results. It did start to make my hands numb after week 10. I was running 4mgs every morning at 5am the last 6 weeks. Definitely less water retention than 3mg of GH daily.

                      EXTROPIANE 1 Reply Last reply
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                      • EXTROPIANE Offline
                        EXTROPIANE Offline
                        EXTROPIAN
                        wrote last edited by
                        #81

                        https://www.instagram.com/reel/DajbldAvdM-/?igsh=ejB5bDZmM2o1ZWRi

                        2M

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                        • J jimmy4407th

                          I’ve run Tesa for 16 weeks while I was waiting for my HGH test results. It did start to make my hands numb after week 10. I was running 4mgs every morning at 5am the last 6 weeks. Definitely less water retention than 3mg of GH daily.

                          EXTROPIANE Offline
                          EXTROPIANE Offline
                          EXTROPIAN
                          wrote last edited by EXTROPIAN
                          #82

                          @jimmy4407th Dial tesa down and be patient. The stuff is is strong even at 1mg. Well for me it is. Water retention, inflammation, tingling... That's you body telling you to chill.
                          Your body has your best interest. It is constantly keeping you alive regardless what you do to it. Be patient and listen to it.

                          2M

                          N 1 Reply Last reply
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                          • EXTROPIANE EXTROPIAN

                            @jimmy4407th Dial tesa down and be patient. The stuff is is strong even at 1mg. Well for me it is. Water retention, inflammation, tingling... That's you body telling you to chill.
                            Your body has your best interest. It is constantly keeping you alive regardless what you do to it. Be patient and listen to it.

                            N Offline
                            N Offline
                            Neil McCauley
                            wrote last edited by
                            #83

                            @EXTROPIAN said:

                            @jimmy4407th Dial tesa down and be patient. The stuff is is strong even at 1mg. Well for me it is. Water retention, inflammation, tingling... That's you body telling you to chill.
                            Your body has your best interest. It is constantly keeping you alive regardless what you do to it. Be patient and listen to it.

                            Similar experiences. 1mg is plenty if your pituitary is functional. Especially if you're running Ipamorelin (which you should be) alongside it.

                            EXTROPIANE 1 Reply Last reply
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                            • N Neil McCauley

                              @EXTROPIAN said:

                              @jimmy4407th Dial tesa down and be patient. The stuff is is strong even at 1mg. Well for me it is. Water retention, inflammation, tingling... That's you body telling you to chill.
                              Your body has your best interest. It is constantly keeping you alive regardless what you do to it. Be patient and listen to it.

                              Similar experiences. 1mg is plenty if your pituitary is functional. Especially if you're running Ipamorelin (which you should be) alongside it.

                              EXTROPIANE Offline
                              EXTROPIANE Offline
                              EXTROPIAN
                              wrote last edited by
                              #84

                              @Neil-McCauley The reason I am even doing Tesa is because I have a kit with one vial reconstituted. It was from a CJC+Ipa no dac and tesa stack I was going to run. I had the local histamine reaction from CJC+Ipa that I couldn't tolerate for a daily dose. I kept my tesa and here I am. There has been good results from a Reta/tesa stack. I'm been running Reta for a while and now running Tesa.

                              2M

                              1 Reply Last reply
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                              • vpepsV Offline
                                vpepsV Offline
                                vpeps
                                wrote last edited by
                                #85

                                I know that Tesa "burns belly fat", I wonder is it know to "burn belly" i.e. to cause a stinging injection site pain?

                                attentiion is all you need

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                                • pep_researcherP Offline
                                  pep_researcherP Offline
                                  pep_researcher
                                  wrote last edited by
                                  #86

                                  If Tesa 600mcg has improved deep and REM sleep and giving some fluid retention on feet, should 🐀 assume it's working on reducing fat too?

                                  Or should 🐀 go to 1mg and beyond? Rat started just about 3 weeks ago and gradually upped from 400mcg to 600mcg. Rat is not very overweight, but rat's lipids aren't optimal hinting liver and visceral fat (Skinny Fat kindaa situation).

                                  EXTROPIANE 1 Reply Last reply
                                  1
                                  • pep_researcherP pep_researcher

                                    If Tesa 600mcg has improved deep and REM sleep and giving some fluid retention on feet, should 🐀 assume it's working on reducing fat too?

                                    Or should 🐀 go to 1mg and beyond? Rat started just about 3 weeks ago and gradually upped from 400mcg to 600mcg. Rat is not very overweight, but rat's lipids aren't optimal hinting liver and visceral fat (Skinny Fat kindaa situation).

                                    EXTROPIANE Offline
                                    EXTROPIANE Offline
                                    EXTROPIAN
                                    wrote last edited by EXTROPIAN
                                    #87

                                    @pep_researcher I can not get passed 1mg without feeling something. I got writers lock ,now some mid back stiffness and some dysesthesia. I had to dial it back to 600mcgs. Pros it has suppressed my appetite a lil more on top of reta. I am trimming slowly. This one I have to watch for though. I don't mind, it gives me an extra week with a 10mg vial. I am about finding the lowest most effective dose and patients. If the symptoms persist I'll dialed it down even more.

                                    2M

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                                    • C Offline
                                      C Offline
                                      Commander
                                      wrote last edited by
                                      #88

                                      I have a good friend that was on 2mg a night. She started getting tingling in her hands. She back it down to 1.5mg and it was better, but still had some tingling. She is going to back it down to 1mg and see if that gets rid of the side effects.
                                      But the funny thing is she was on 2mg for months with no problems. She is pissed because she gets great sleep with Tesa/IPA.

                                      Please excuse my typos. Small Phone & Bad Eyes

                                      M 1 Reply Last reply
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                                      • C Commander

                                        I have a good friend that was on 2mg a night. She started getting tingling in her hands. She back it down to 1.5mg and it was better, but still had some tingling. She is going to back it down to 1mg and see if that gets rid of the side effects.
                                        But the funny thing is she was on 2mg for months with no problems. She is pissed because she gets great sleep with Tesa/IPA.

                                        M Offline
                                        M Offline
                                        MikeMiranda
                                        wrote last edited by
                                        #89

                                        @Commander The 2mg maximum dosage applies to the original version of Egrifta, not the Egrifta WR and Egrifta SV that are available now. I believe the recommended doses are 1.28mg for WR and 1.4mg for SV.

                                        C 1 Reply Last reply
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                                        • M MikeMiranda

                                          @Commander The 2mg maximum dosage applies to the original version of Egrifta, not the Egrifta WR and Egrifta SV that are available now. I believe the recommended doses are 1.28mg for WR and 1.4mg for SV.

                                          C Offline
                                          C Offline
                                          Commander
                                          wrote last edited by
                                          #90

                                          @MikeMiranda said:

                                          @Commander The 2mg maximum dosage applies to the original version of Egrifta, not the Egrifta WR and Egrifta SV that are available now. I believe the recommended doses are 1.28mg for WR and 1.4mg for SV.

                                          Didn't know there was different ones. So what one is the one that we get when we buy it?

                                          Please excuse my typos. Small Phone & Bad Eyes

                                          M S 2 Replies Last reply
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