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  1. Randy the Rats Research Forum
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  3. Tesamorelin Research Dosing Protocol
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Tesamorelin Research Dosing Protocol

Scheduled Pinned Locked Moved Peptide Discussion
tesamorelinresearching
71 Posts 26 Posters 5.7k Views 2 Watching
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  • hunt_akH hunt_ak

    The HR increase/pounding for the first bit after dosing CJC is definitely something that tells me 'hello, I'm working in here!' haha

    I do have a vial of Tesa that I'm going to do when I cycle off the CJC/Ipa blend for 4 weeks. We shall see how it goes!

    N Offline
    N Offline
    Neil McCauley
    wrote last edited by Neil McCauley
    #62

    @hunt_ak said:

    The HR increase/pounding for the first bit after dosing CJC is definitely something that tells me 'hello, I'm working in here!' haha

    I do have a vial of Tesa that I'm going to do when I cycle off the CJC/Ipa blend for 4 weeks. We shall see how it goes!

    I don't get the increased HR, but I do get the warm fuzzy flushy feeling in my face. I actually like it, especially on a chilly morning inside a cold laboratory in a northern climate. Good way to start the day.

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    • 5 Offline
      5 Offline
      50PLUSFIT
      wrote last edited by
      #63

      Well, @randy has done a video on the comment I posted earlier, regarding refrigeration of Tesa.
      For anyone interested: https://www.youtube.com/watch?v=D1AwgJ-S-vY

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      • C Offline
        C Offline
        Commander
        wrote last edited by
        #64

        I wonder if you dilute it more of it makes a difference.

        Please excuse my typos. Small Phone & Bad Eyes

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        • C Offline
          C Offline
          Commander
          wrote last edited by
          #65

          I have 20mg vials coming in a couple of days, so I guess I will find out

          Please excuse my typos. Small Phone & Bad Eyes

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          • C Commander

            I have 20mg vials coming in a couple of days, so I guess I will find out

            N Offline
            N Offline
            Neil McCauley
            wrote last edited by Neil McCauley
            #66

            @Commander said:

            I have 20mg vials coming in a couple of days, so I guess I will find out

            I have seen those around, and was previously thinking that 20 days is way too long to have Tesa recon in use (I go 1mg per day).

            Your experiences have me thinking otherwise. I try not to get dogmatic about things and I will experiment and tinker if it makes sense, within reason.

            I have previously ran them for 10 days (not fridged) with no issues at all.

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            • MacLeeezyM MacLeeezy

              I’d love to see @randy run his next batch of testing on research grade Tesa, so we can finally see if it stays potent for a few weeks after reconstitution and if being in the fridge or room temp really matters (pretty please)?

              E Offline
              E Offline
              Eleanor
              wrote last edited by
              #67

              @MacLeeezy said:

              I’d love to see @randy run his next batch of testing on research grade Tesa, so we can finally see if it stays potent for a few weeks after reconstitution and if being in the fridge or room temp really matters (pretty please)?

              I have 2 vials of 10mg Tesa powder in the fridge from Penguin I will donate to Randy if he will test. Might as well donate it bc I can't take it with the side effects.

              @randy What says you, rat?

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              • C Offline
                C Offline
                Commander
                wrote last edited by
                #68

                I have put 3 10mg vials in a cart before and have used 1.5mg a day, I haven’t had any problems so far. I only use Hospira, not sure if that makes a difference or not

                Please excuse my typos. Small Phone & Bad Eyes

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                • E Eleanor

                  @MacLeeezy said:

                  I’d love to see @randy run his next batch of testing on research grade Tesa, so we can finally see if it stays potent for a few weeks after reconstitution and if being in the fridge or room temp really matters (pretty please)?

                  I have 2 vials of 10mg Tesa powder in the fridge from Penguin I will donate to Randy if he will test. Might as well donate it bc I can't take it with the side effects.

                  @randy What says you, rat?

                  E Offline
                  E Offline
                  Eleanor
                  wrote last edited by
                  #69

                  Oh, sorry @randy , you've already done that. Pardon.

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                  • N Neil McCauley

                    @jborja said in Tesamorelin Research Dosing Protocol:

                    Hey friends, @randy might have opined on this also, but curious to hear what others think. I saw another video that nightly tesamorelin might be impacted for those taking Tirz or Reta due to slowed gastric emptying, meaning that folks are not as truly fasted and still carrying heavier insulin when they poke before bed.
                    I like Tesamorelin/ipa at nights due to restful and deeper sleep (even with toddlers), but I am on tirz and try to have my last bite 3 hours before bed. Not sure if eating dinner 4 hrs before is doable..
                    Curious to hear your thoughts about a morning routine instead? For you morning folks, do you just wait at least 30 mins before a pre workout? I was gonna try Tesa at night and Cjc in the morning but might be reconsidering this to not have duplicative secretagogues at the same time. Ty!

                    I only research my GHRH/GHRP peptides in the a.m., first thing fasted now, for a whole bunch of reasons. It's just easier and more convenient for me, I know I'm totally fasted with insulin at its lowest point (and therefore getting the strongest amount of receptor saturation as possible).

                    Plus I'm just more awake/alert in the a.m., easier to pin and reconstitute if need be. I spent many late nights in years past pinning/researching before bed after a long day and when tired, it's just difficult.

                    I wait 2 hours before eating anything. I drink black coffee right away in the morning after pinning and the combo of peptides, coffee and being fasted in the a.m. is a superpower for getting stuff done. Plus I find GH peptides stimulating in a way in the morning.

                    I like the idea of going natural at night (no GH peps) and really letting my natural production do its thing. I have found that there must be some carry over anyways, because on cycle my rat sleeps better even though he pins in the a.m only.

                    Rather than trying to find a way to squeeze in Tesa/CJC in the same day, I'd recommend you use one or the other during your cycle. You can flip flop them as well, going back and forth when one vial runs out.

                    vpeptidesV Online
                    vpeptidesV Online
                    vpeptides
                    wrote last edited by vpeptides
                    #70

                    @Neil-McCauley said:

                    I know I'm totally fasted with insulin at its lowest point

                    You should really test your daily insulin fluctuation (through correlation with glucose) with 15-days CGM to know levels and timings exactly. I ran CGMs many times, and when I wake up my insulin level is not the lowest of the day. There is so-called "dawn effect" starting at around an hour before you wake up and going for some time, when your insulin goes high because glucose go high because of raising cortisol.

                    Here is how it looked for me, and I wake up at 6-7. See, there is a raise around the wake time and then it goes down around 7:30a. You can make it personally adjusted, knowing the short half-life of these molecules it may be worth doing.
                    ea7bba63-f6aa-479d-9a7a-2fb6962b0be7-image.jpeg

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                    • L lancerlot23

                      I’ve been taking Tesamorelin for 2 weeks—1 mg during the first week and 2 mg at night during the second week. I inject it about 30 minutes before bed, with no food for at least 3 hours beforehand.
                      Since starting it, my nighttime heart rate has increased. My average resting heart rate used to be around 60, but recently it’s been 86, 70, and 69. My stress levels have been very high, I’m not getting any REM sleep, and I’m having trouble sleeping overall.
                      I know that this is an evening Peptide, but would AM hour work better maybe? I could pause for a couple of days and see if my heart rate and sleep normalize also.

                      J Offline
                      J Offline
                      JtCjEfF
                      wrote last edited by
                      #71

                      @lancerlot23 Any update on how this went? Researching Reta and Im +10 bpm, with the same negative results you mention. Last thing i need is more BPM's!

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