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Tesamorelin Research Dosing Protocol

Scheduled Pinned Locked Moved Peptide Discussion
tesamorelinresearching
120 Posts 42 Posters 14.4k Views 4 Watching
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  • WisGal64W WisGal64

    I left a review for crush when they weren’t listed because I understood it to be open. Think they get added based on reviews?

    R Offline
    R Offline
    RagnatLothbrok
    wrote last edited by
    #16

    @WisGal64 oh really? I deleted my post because it didn’t have a tag for the vendor. But I’ll re-upload it

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    • ResearchCatR ResearchCat

      Thoughts on doing a Tesa/Ipa protocol? I was watching a video yesterday talking about doing that with a morning injection schedule to take advantage of overnight fasting and then not eating for a few hours. This would work well for intermittent fasting regimens, might help with sleep, and is supposed to be better for shredding.

      I just finished a CJC/IPA cycle and between the challenge of fasting (I don’t get home til after 9 a lot) and not sleeping great on it, I’m thinking about alternatives down the road. CJC/IPA definitely works for me but might not be ideal, and sermorelin is quite subtle.

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      beachfun
      wrote last edited by
      #17

      @ResearchCat I was doing my second vial of chc/ipa and was really loving the sleep and recovery. I heard a video of adding tesamoreline so added .5 mg then stopped the cjc and was doing 1 mg of Tesa at night for a week. I had one more dose left but I tossed it.
      My back got sore, my joints were stiff and it felt like tesa was working completely against my recovery stack.
      Last night, my sleep wasn’t as good and needed to take a KPV to help with all that inflammation. I also ate some yogurt which hunger seems to be working against the body composition goals. Im going to the hotsprings, taking the weekend off and may restart my cjc/ipa Monday night. I also did a BPC 157 this morning with another KPV, which is helping. Tesa is NOT for me…

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        Eleanor
        wrote last edited by
        #18

        Well, all this just kinda blows me out of the water. I need to get rid of a lot of visceral fat; I mean A LOT. The DEXA was horrible! I'm not that overweight, but the Dr. said, and I concur, it's been there a long time and I was raised on a Southern diet. I'm currently taking Tirzep once/wk on Friday night; nothing to eat since lunch, except very light snack later so stomach's not growling. NAD+ M,W & Sat, mornings upon waking, approx 10 hour fast. I have trouble sleeping and get up at 4:30, so not sure where to fit in Tesa. Question for all, but esp. for @randy Do Tesa and NAD+ work well together? I can cut back on the NAD, but not the Tirzep. I could also stay on lower does of Tesa for longer. What do y'all think?

        Proud to be on a gubmint watch list

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          Eleanor
          wrote last edited by Eleanor
          #19

          M.D.? Someone mentioned somewhere on this blog that all the influencers out there are DC's or anything other than MD's. Maybe this one is MD? Got to go to work right now but will look up licensing this weekend.
          https://youtu.be/Ky5Hodz3-9A?si=P0iLJhekK0GujTSo

          Proud to be on a gubmint watch list

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          • ResearchCatR Offline
            ResearchCatR Offline
            ResearchCat
            wrote last edited by
            #20

            What is the NAD+ for? I don’t know your history or goals, but almost think that MOTS-C might be more effective if you are trying to burn fat, especially if you are exercising.

            I see no issues researching NAD+/MOTS-C with a GHRH. You can research Tesa/Ipa/CJC first thing in the morning fasted or an hour before bed after fasting 2-3 hours.

            I am not a doctor, or your doctor, but I like to have a specific goal and purpose for whatever peptides I am researching, even if I am researching several at the same time. ;). At the moment, I am much more bullish on MOTS-C than on NAD+ as part of an ongoing maintenance stack.

            Yeah, well, I’m just here for the research, man. - The Dude

            If I haven’t liked your post, no offense. I have exceeded my daily allowance.

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            • ResearchCatR ResearchCat

              What is the NAD+ for? I don’t know your history or goals, but almost think that MOTS-C might be more effective if you are trying to burn fat, especially if you are exercising.

              I see no issues researching NAD+/MOTS-C with a GHRH. You can research Tesa/Ipa/CJC first thing in the morning fasted or an hour before bed after fasting 2-3 hours.

              I am not a doctor, or your doctor, but I like to have a specific goal and purpose for whatever peptides I am researching, even if I am researching several at the same time. ;). At the moment, I am much more bullish on MOTS-C than on NAD+ as part of an ongoing maintenance stack.

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              Eleanor
              wrote last edited by Eleanor
              #21

              @ResearchCat NAD+ really kept me on my feet when I first started Tirzep; I still have 4 vials of it and am going to use it. Depending on how I'm feeling when I've used it up will determine if I buy more. When something works, I try not to change it. Problem is that I get relatively wired on it; I have a high stress job, and have trouble sleeping. I've recently reduced the dose, so will see if I can find a sweet spot. Thanks for the ideas! I imagine I will try a number of them before all's said and done.

              Proud to be on a gubmint watch list

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              • ResearchCatR Offline
                ResearchCatR Offline
                ResearchCat
                wrote last edited by
                #22

                If you are suffering a loss of energy while on Tirz, it may be because you aren’t eating enough. I know it is hard to do, but when I was above 7.5 mg tirz, I had to force myself to eat in order to hit my macros. At 10mg, I had no desire to eat at all, so I started lowering the dose.

                I am not telling you what to do, but if you can add in exercise, or continue a structured workout program, you will probably find Tesa and MOTS-C to be game-changing additions. IMO, adding these in and not 1) eating enough and 2) exercising, will diminish the potential benefits of using them.

                Yeah, well, I’m just here for the research, man. - The Dude

                If I haven’t liked your post, no offense. I have exceeded my daily allowance.

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                • ResearchCatR Offline
                  ResearchCatR Offline
                  ResearchCat
                  wrote last edited by
                  #23

                  Also, I totally understand the high stress job thing. 😉

                  Yeah, well, I’m just here for the research, man. - The Dude

                  If I haven’t liked your post, no offense. I have exceeded my daily allowance.

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                  • ResearchCatR ResearchCat

                    If you are suffering a loss of energy while on Tirz, it may be because you aren’t eating enough. I know it is hard to do, but when I was above 7.5 mg tirz, I had to force myself to eat in order to hit my macros. At 10mg, I had no desire to eat at all, so I started lowering the dose.

                    I am not telling you what to do, but if you can add in exercise, or continue a structured workout program, you will probably find Tesa and MOTS-C to be game-changing additions. IMO, adding these in and not 1) eating enough and 2) exercising, will diminish the potential benefits of using them.

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                    Eleanor
                    wrote last edited by
                    #24

                    @ResearchCat I understand your concern. I'm eating plenty, trust me! I have other considerations, ex: I had an advanced case of Lyme Disease and 3 co-infections that took about 13 years (on & off) to get under control. Somewhere during that process, I lost 5.5' of bowel; to say I have absorption problems is an understatement, plus the MTHFR. There's a long laundry list my 70 yrs has collected. The energy loss started from the very beginning, but love the weight loss results. I think I'm probably taking NAD too many times per week, or too much. I cannot toss peps to the side, unless they're truly making me ill; my budget is so limited. Experimenting right now to find a good mix.

                    I definitely want to add Tesa and will just have to deal with more experimenting.

                    Proud to be on a gubmint watch list

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                    • E Eleanor

                      Well, all this just kinda blows me out of the water. I need to get rid of a lot of visceral fat; I mean A LOT. The DEXA was horrible! I'm not that overweight, but the Dr. said, and I concur, it's been there a long time and I was raised on a Southern diet. I'm currently taking Tirzep once/wk on Friday night; nothing to eat since lunch, except very light snack later so stomach's not growling. NAD+ M,W & Sat, mornings upon waking, approx 10 hour fast. I have trouble sleeping and get up at 4:30, so not sure where to fit in Tesa. Question for all, but esp. for @randy Do Tesa and NAD+ work well together? I can cut back on the NAD, but not the Tirzep. I could also stay on lower does of Tesa for longer. What do y'all think?

                      B Offline
                      B Offline
                      beachfun
                      wrote last edited by
                      #25

                      @Eleanor Instead of Tesa you may want to try Survo with your Tirzepatide first. That with hit your glucagon receptor and cause you to burn fat for energy like a Reta effect. Also I ran 5 amino 1mq when I stalled and it helps with energy by blocking NAD loss

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                      • B beachfun

                        @Eleanor Instead of Tesa you may want to try Survo with your Tirzepatide first. That with hit your glucagon receptor and cause you to burn fat for energy like a Reta effect. Also I ran 5 amino 1mq when I stalled and it helps with energy by blocking NAD loss

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                        Eleanor
                        wrote last edited by Eleanor
                        #26

                        @beachfun Thanks for the idea! Does Survo target belly fat? What vendor do you like to research with? My weight hasn't really stalled, but the belly fat concentration is high. I'm fearful of Tesa because of the possibly of edema and joint pan; both of which I already have because of a desk job. Any additional might be unbearable, esp. at my age (70).

                        Proud to be on a gubmint watch list

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                        • judgetooJ judgetoo

                          Want to give a shoutout to Tesa from a 60-year-old male. I have been injecting 1mg Sun-Thurs for 12 weeks (among other things including Testosterone, Reta, GHK-Cu and Semax/Selank). Scan from yesterday showed a drop in visceral fat from 112 cm² to 70.3 cm² (37% reduction). Obviously, the Testosterone and Reta played a part, but I can definitively say it helped me. I'm a big fan. I'm taking a 2-week break and will start another cycle again. Can't say enough good things.

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                          Eleanor
                          wrote last edited by
                          #27

                          @judgetoo said:

                          Want to give a shoutout to Tesa from a 60-year-old male. I have been injecting 1mg Sun-Thurs for 12 weeks (among other things including Testosterone, Reta, GHK-Cu and Semax/Selank). Scan from yesterday showed a drop in visceral fat from 112 cm² to 70.3 cm² (37% reduction). Obviously, the Testosterone and Reta played a part, but I can definitively say it helped me. I'm a big fan. I'm taking a 2-week break and will start another cycle again. Can't say enough good things.

                          What time of day of the injection? Thanks!

                          Proud to be on a gubmint watch list

                          judgetooJ 1 Reply Last reply
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                            Neil McCauley
                            wrote last edited by Neil McCauley
                            #28

                            I find it very curious (and awesome btw) that so many older people are experiencing such positive effects from tesamorelin. That tells me a couple things. First, it means the pituitary somatotrophs, even when in advanced age, can still function with proper exogenous help.

                            Second, that means other GHRH peptide drugs would work on those same people, because if Tesa is working (via GHRH stimulus) then the others must work to some (or full) extent as well.

                            The ongoing, and previously published tesa clinical data used many older patients, all with what should be a pretty harsh comorbitity all things considered (AIDS & advanced age) and despite this, produced a strong GHRH response from the pituitary. Same with the Sermorelin data from years past as well.

                            All this and I'm pretty sure the study participants were nowhere near as rigorous with there research as we are in terms of pinning around fasted times. I'm certain that none of the Sermorelin data participants even bothered with this at all (this was an unknown benefit at the time) and I don't think the Tesa participants did either but I'm not certain about that. Imagine how much better the results would have been had they made that a priority in their protocols.

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                            • E Eleanor

                              @judgetoo said:

                              Want to give a shoutout to Tesa from a 60-year-old male. I have been injecting 1mg Sun-Thurs for 12 weeks (among other things including Testosterone, Reta, GHK-Cu and Semax/Selank). Scan from yesterday showed a drop in visceral fat from 112 cm² to 70.3 cm² (37% reduction). Obviously, the Testosterone and Reta played a part, but I can definitively say it helped me. I'm a big fan. I'm taking a 2-week break and will start another cycle again. Can't say enough good things.

                              What time of day of the injection? Thanks!

                              judgetooJ Offline
                              judgetooJ Offline
                              judgetoo
                              wrote last edited by
                              #29

                              @Eleanor I was injecting right before bedtime.

                              1 Reply Last reply
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                              • R Offline
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                                rburger01
                                wrote last edited by
                                #30

                                How much BAC are people adding to a !0MG Tesamorelin Vile for their experiments?

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                                • R rburger01

                                  How much BAC are people adding to a !0MG Tesamorelin Vile for their experiments?

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                                  TBone
                                  wrote last edited by TBone
                                  #31

                                  @rburger01 I’m researching 2mg a day M-F. I use 2ml BAC in a 10mg vial. Daily dosage is 40 units.

                                  Comfort is the worst addiction - Marcus Aurelius

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                                  • ResearchCatR Offline
                                    ResearchCatR Offline
                                    ResearchCat
                                    wrote last edited by
                                    #32

                                    @rburger01
                                    Tonight I am mixing up 4 vials into one cart with 3ml bac water and will research 14 units ~2mg/day.

                                    I research first thing after waking up (fasted) and typically don’t eat for 2 hours.

                                    Yeah, well, I’m just here for the research, man. - The Dude

                                    If I haven’t liked your post, no offense. I have exceeded my daily allowance.

                                    1 Reply Last reply
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                                    • ResearchCatR Offline
                                      ResearchCatR Offline
                                      ResearchCat
                                      wrote last edited by
                                      #33

                                      @neil-mccauley I have researched Serm, Tesa, and CJC/Ipa and I can tell you with 100% certainty they work. I think the reason CJC/Ipa has the reputation and popularity it does is that you start noticing results in weeks, not months. Sermorelin is ‘gentler’ and takes months to notice a difference(great for revenue streams at the T clinic). I am only a few weeks into Tesa and have been injured so I can’t speak to results yet.

                                      Yeah, well, I’m just here for the research, man. - The Dude

                                      If I haven’t liked your post, no offense. I have exceeded my daily allowance.

                                      1 Reply Last reply
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                                      • ResearchCatR Offline
                                        ResearchCatR Offline
                                        ResearchCat
                                        wrote last edited by
                                        #34

                                        Week 4 of Tesa and my Hume is telling me that my visceral fat index is up. Not sure exactly what that means. Will continue to monitor through the next month as I get back into a full workout schedule. After that will be cycling back to CJC/Ipa.

                                        Yeah, well, I’m just here for the research, man. - The Dude

                                        If I haven’t liked your post, no offense. I have exceeded my daily allowance.

                                        1 Reply Last reply
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                                        • B Offline
                                          B Offline
                                          BlatantlyObviousXL
                                          wrote last edited by
                                          #35

                                          I ordered from a vendor and they sent me 'free' sterile water with a note that said we reccomend sterile water instead of BAC. I am confused since I was going to use the 10mg within a week. So watching Randy's video, I should be fine and not have the thickening issue. Is this correct?

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