Can a Peptide Pen Handle Testosterone? I Tested It
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Apologies if this is the incorrect place for this post. I figure it has to do with pens, so this may work?
I've recently made the switch to peptide pens and have become a huge fan of the convenience and consistency (thanks Randy!). Since I'm also on TRT, I started wondering whether testosterone could be used with pens as well.
After finding a forum thread where several people were doing exactly that, I decided to run some tests of my own.
Goal: Determine whether Testosterone Cypionate can be delivered accurately and consistently through a peptide pen.
Setup:
Pen: ConviPen (auto-injector)
Testosterone: Testosterone Cypionate 200 mg/mL in cottonseed oil
Needles: EasyTouch 29g 1/2" pen needlesI chose the ConviPen because it uses a metal drive rod and I suspected an auto-injector would have an easier time pushing a more viscous oil. I am still considering testing a manual pen (V4) for comparison.
Testing Performed:
Test #1: I loaded a cart into the pen and measured output directly into an insulin syringe. To do this, I inserted the syringe into the cart and dispensed a dose from the pen, allowing me to measure the volume.Approximately 10 repetitions were performed.
Result:
Output was extremely consistent.
15 units delivered essentially what was expected each time.Test #2: I then attached a 29g pen needle and repeated the testing by dispensing through the needle into the open end of a syringe. This method was less precise than Test #1, as some of the oil adhered to the sides of the syringe and could not be measured perfectly.
Approximately 30+ repetitions were performed.
Result:
Output remained consistent.
Measured delivery was roughly 1 unit lower than expected.
Because of this, I began testing a setting of 16 units to achieve an effective 15-unit delivery.Test #3: I then did an actual subcu injection for my regular dose. When I pressed the trigger at 16 units, the dose indicator rapidly dropped to approximately 5 units remaining, then continued clicking all the way down to 0. I left the needle in place for approximately 10 seconds after the indicator reached 0.
This behavior was very different from my syringe testing and raises the question of whether tissue resistance affects delivery compared to bench testing.
Preliminary Conclusions:
• Testosterone Cypionate in cottonseed oil can be delivered through a peptide pen.
• A 29g pen needle appears to work (shout out to the forum users who stated this in another post!!)
• Pens are mechanically capable of pushing oil-based testosterone.
• I still need long-term validation through TRT labs to confirm that Total Testosterone and Free Testosterone remain consistent with pre-pen values.
• I am unsure whether an auto-injector or manual pen is ultimately the better platform for oil-based compounds.Questions: For those who have experimented with TRT in peptide pens:
• Have you found auto-injectors or manual pens to be more reliable?
• Has anyone validated dose accuracy through bloodwork or measured output testing?
• What are some other factors I should be considering?I'm still early in this experiment, but so far, things are looking promising!
P.S. For those wondering, I wasn't burning through my actual TRT supply for science. A friend had an old blended testosterone vial that was never going to be used, so it became the sacrificial test subject for this project.
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I am doing the same thing by using a V4 pen with my TRT. I was tired of backfilling insulin syringes and making a mess. I’m using a 29g x 1/2” from TRUEplus (Amazon). I tested it similarly to what you described although you were much more thorough. I loaded a syringe a couple of times and it looked accurate enough for me. I’ve been doing it that way for about a month now.
I pen 17u every other day for an average of 120mg per week. Just had my labs done and everything looked good as far as my doctor was concerned. I haven’t noticed any changes in how I feel, gym performance or libido.
This is just my experience. I’m by no means an expert in any of this but wanted to let you know you’re not alone in this experiment. It works for me.
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@Nuncles You can also inject trt SubQ.
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I was doing this successfully with a 1/2 inch needle when I did the daily schedule. No problems. I also put it through a .22 13mm filter. It takes patience. But it goes. The trick is patience due to the high viscosity.
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I am doing the same thing by using a V4 pen with my TRT. I was tired of backfilling insulin syringes and making a mess. I’m using a 29g x 1/2” from TRUEplus (Amazon). I tested it similarly to what you described although you were much more thorough. I loaded a syringe a couple of times and it looked accurate enough for me. I’ve been doing it that way for about a month now.
I pen 17u every other day for an average of 120mg per week. Just had my labs done and everything looked good as far as my doctor was concerned. I haven’t noticed any changes in how I feel, gym performance or libido.
This is just my experience. I’m by no means an expert in any of this but wanted to let you know you’re not alone in this experiment. It works for me.
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@Nuncles I poked IM for maybe a year or so because I was taught that was the only way for it to be effective. I made the change to subcu and have been doing that for years. Labs have been consistent (I run them every 90 days because I'm a freak). For me switching to subq was a HUGE QOL improvement. I rotate injection sites on my thighs
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I am doing the same thing by using a V4 pen with my TRT. I was tired of backfilling insulin syringes and making a mess. I’m using a 29g x 1/2” from TRUEplus (Amazon). I tested it similarly to what you described although you were much more thorough. I loaded a syringe a couple of times and it looked accurate enough for me. I’ve been doing it that way for about a month now.
I pen 17u every other day for an average of 120mg per week. Just had my labs done and everything looked good as far as my doctor was concerned. I haven’t noticed any changes in how I feel, gym performance or libido.
This is just my experience. I’m by no means an expert in any of this but wanted to let you know you’re not alone in this experiment. It works for me.
@judgetoo Great info! Thanks for sharing! When Noble and I ran these accuracy tests we held the needle for 10 seconds to ensure the best accurate dose due to the viscosity of T. Question I have is how long you kept the needle inside before removing from the skin?
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@judgetoo Great info! Thanks for sharing! When Noble and I ran these accuracy tests we held the needle for 10 seconds to ensure the best accurate dose due to the viscosity of T. Question I have is how long you kept the needle inside before removing from the skin?
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@judgetoo Thanks for sharing this! Have you tried an auto-injector by chance? After I do a few more months with my current setup, I'll likely try out test with a V4.
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@kenhnsy just curious, why would you filter trt?
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@kenhnsy just curious, why would you filter trt?
Mine is all USP prescription stuff. But I found particles in a vial which had to come from the puncture cap. So filtering can only be a good thing for all injectables.
@kenhnsy That's cool! I'm all about filtering, but if I were you, and you're going to filter your trt, I would use a 25mm PTFE (Polytetrafluoroethylene) .22 micron filter. It's considered the best choice for oil-based solutions like trt.
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Im currently using a xulin pen for test-cip at 14iu per day of 200mg/ml Sub-q. I use 30ga gluco-care needles and I have to let the needle stay in my belly for 30-40 seconds or so to make sure I dont leave pressure in the vial and an inaccurate does in my belly. I'm a fan of injecting daily.
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