Mots-c dosing
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my rat is ding 1mg per dose, 3xweek. Effect on endurance is very noticable, as in, being able to run longer and easier at higher heart rate zones (4 and 5). So i see no need yet to increase to 2mg per injection, mots-c is not that cheap after all (relatively speaking).
@eurouser Interesting I was doing 2mg a day and getting a nice ISR but dealt with it. I have had noticeable physical fitness results running. My sprint times have gotten noticeably better. I just switched yesterday to saline BAC, and it made a massive difference in my last two shots no ISR at all. A little itchy feeling for a couple of minutes but thats it. I am thinking about reducing it to 1mg a day. I can't see taking 4-5mg at one time
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@eurouser Interesting I was doing 2mg a day and getting a nice ISR but dealt with it. I have had noticeable physical fitness results running. My sprint times have gotten noticeably better. I just switched yesterday to saline BAC, and it made a massive difference in my last two shots no ISR at all. A little itchy feeling for a couple of minutes but thats it. I am thinking about reducing it to 1mg a day. I can't see taking 4-5mg at one time
@Stevepep what exact differences did you notice with sprinting? i'm really interested in that as i am planning on getting back to sprinting once i lose the remaining 20lbs.
One thing that helped my rat with ISR btw was to wait a second after every 2 clicks. Say total pin dosage is 10 units, he would pause 5 times. It made ISR almost completely gone (only using normal BAC water)
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@Stevepep what exact differences did you notice with sprinting? i'm really interested in that as i am planning on getting back to sprinting once i lose the remaining 20lbs.
One thing that helped my rat with ISR btw was to wait a second after every 2 clicks. Say total pin dosage is 10 units, he would pause 5 times. It made ISR almost completely gone (only using normal BAC water)
@eurouser Its an interesting thing I am associating with the Stack of SS31, NAD and Mots. I was running 4 miles at about 7:30 per mile without a sprint at the end. I do this 4x per week and lift heavy the other 3 days. I am now running 7:12 minute miles for 3 miles and sprint the last mile and I am getting just over a 6 minute mile on that last mile. When I do this on the treadm1ll I am running 3 miles at 8.5 to 9 and then last at 12. Its pretty crazy. I am in my mid 50's. I literally never had the energy to even think about sprinting at the end. One other thing I added was branched cyclic dextrin. @bfuller turned me on to it for high stress workouts. I think it has helped a lot as well. I feel fully recovered after I workout and I had high Estrogen in my monthly bloodwork, which is an indicator of lack of recovery. My estrogen levels are now Optimum.
In terms of sprinting I run 1/4miles on the treadmill at 15 which takes a minute and then walk for one minutes and do it again. 4x. I typically do this once a week after lifting. This is excellent heart exercise, with peaks and valleys.
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@jackiee I'd never heard of it before but found some here...
https://www.mountainside-medical.com/products/bacteriostatic-sodium-chloride-0-9-vial-10-ml -
@eurouser Its an interesting thing I am associating with the Stack of SS31, NAD and Mots. I was running 4 miles at about 7:30 per mile without a sprint at the end. I do this 4x per week and lift heavy the other 3 days. I am now running 7:12 minute miles for 3 miles and sprint the last mile and I am getting just over a 6 minute mile on that last mile. When I do this on the treadm1ll I am running 3 miles at 8.5 to 9 and then last at 12. Its pretty crazy. I am in my mid 50's. I literally never had the energy to even think about sprinting at the end. One other thing I added was branched cyclic dextrin. @bfuller turned me on to it for high stress workouts. I think it has helped a lot as well. I feel fully recovered after I workout and I had high Estrogen in my monthly bloodwork, which is an indicator of lack of recovery. My estrogen levels are now Optimum.
In terms of sprinting I run 1/4miles on the treadmill at 15 which takes a minute and then walk for one minutes and do it again. 4x. I typically do this once a week after lifting. This is excellent heart exercise, with peaks and valleys.
@Stevepep oh i see, you mean the "final sprint" at the end of the run not sprinting as a sport. In any case, i had the same results in that regard, as in, huge benefit in the higher heart rate zones. At your age, if you are running 7:12 for 3 miles, that means your heart rate is already around 170 minimum at the end of those three miles, so the fact that you can get to a 6 minute pace on the last mile is exactly zone 5 training which you are holding for much longer than "considered normal".
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3-5mg subcutaneous, 1β3Γ per week. 4β6 weeks on, 2β4 weeks off. Morning dosing, typically 60β90 min before exercise.
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What are your thoughts on MOTS-C now? Is it worth the money and the risk?
If yes, are you using it regularly or cycling?@mmp Not sure if your question was for me, but for me personally it helped me a lot. Using it in conjunction with a GLP-1, L-Carnitine, NAD+ and SS-31, gave me the necessary energy for my workouts. Over the last 30+ years, I didn't lead that healthy of a lifestyle, so when I started to learn about the possible metabolic improvement benefits of MOTS-c and had to give it a try. Now for someone that is younger and lives a pretty healthy lifestyle, you probably won't see much benefit from MOTS-c. But my last cycle for this stack I ran for 12 weeks.
SS-31 runs daily through week 8; after that, continue daily while the response is still building or move to 2β3Γ weekly once stable. Maintenance protocols pulse MOTS-c alongside NAD+ at 100β250 mg total weekly. MOTS-c enters in week 2 once the opening SS-31 response is stable.
If you do decide to try MOTS-c, begin with a low dose to see how well you tolerate it, and titrate slowly as well. And I have seen examples of folks when they go to start a 2nd cycle they have a very serious allergic reaction to the MOTS-c. So just use caution.

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