What Peptide(s) Did You Expect the LEAST From but Ended Up Impressing You the Most?
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@dispensarysupport I agree across the board.
Many are part of the hype train but largely placebo. I do think there is some validity to the healing compounds. BPC/TB. Hear overwhelming anecdotal evidence toward the addition of KPV. I’m personally quickly becoming a believer in MOTS.
GLPs are a miracle drug. Optimized test and IGF complete the Holy Trinity.
Can I ask, why did you go from Tesa/Ipa to HGH. Are you done with the former or do you alternate?
Many are part of the hype train but largely placebo.
I disagree somewhat. I think that most of these peptides can work, however, unlike GLP-1’s, which will cause you to lose weight even if you do nothing else, many other peptides need to be used correctly in conjunction with lifestyle changes.
When a new person shows up saying they were told to start blasting Reta, Tesa, MOTS-C, and AOD (no shade, new folks), without knowing anything else about them, that sounds like a terrible idea to me. I’ve seen 20 year olds doing that, and it is probably throwing away money, but a 50+ year old who is trying to do all the right things and cycles them properly could see excellent benefits (except maybe the AOD; I’ve seen research showing it to be largely useless; others love it.)
It all depends.
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Many are part of the hype train but largely placebo.
I disagree somewhat. I think that most of these peptides can work, however, unlike GLP-1’s, which will cause you to lose weight even if you do nothing else, many other peptides need to be used correctly in conjunction with lifestyle changes.
When a new person shows up saying they were told to start blasting Reta, Tesa, MOTS-C, and AOD (no shade, new folks), without knowing anything else about them, that sounds like a terrible idea to me. I’ve seen 20 year olds doing that, and it is probably throwing away money, but a 50+ year old who is trying to do all the right things and cycles them properly could see excellent benefits (except maybe the AOD; I’ve seen research showing it to be largely useless; others love it.)
It all depends.
@jdot [said](/post/27549 >
Many are part of the hype train but largely placebo.I disagree somewhat. I think that most of these peptides can work, however, unlike GLP-1’s, which will cause you to lose weight even if you do nothing else, many other peptides need to be used correctly in conjunction with lifestyle changes.
When a new person shows up saying they were told to start blasting Reta, Tesa, MOTS-C, and AOD (no shade, new folks), without knowing anything else about them, that sounds like a terrible idea to me. I’ve seen 20 year olds doing that, and it is probably throwing away money, but a 50+ year old who is trying to do all the right things and cycles them properly could see excellent benefits (except maybe the AOD; I’ve seen research showing it to be largely useless; others love it.)
It all depends.
To add on to this, everyone's body is different. Someone may say NAD+ didn't work for them. But it just may be that their body is still producing it. The same could go for mitochondria, telemores, etc. Essentially some body's may need more help than others.
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Since the title of this thread is, "What Peptide(s) Did You Expect the LEAST From but Ended Up Impressing You the Most?", I can say that I did expect the weight loss peps to work and they do; no surprise with these peps. Was very surprised by KPV to relieve inflammation in my knee but had to take a full mg before it was noticeable. Tried Cartalax and others; all were very temporary and just didn't do it. When I upped the KPV, it was almost overnight. No placebo effect whatsoever with this one. Hoping someday a pep is found to take care of the EBV capsulates that cause the crushing fatigue I have that only let's up a bit with NAD+ & MOTS-C. Trying the Monolithin, on-going, in hopes the report is true that it breaks up the EBV caps left behind, likely to take a long time to do it though (reading 600+). I have no intention of trying a lot of new peps or supps. My gut can't handle oral supps or more peps and neither can my bank acct. I'll just have to deal with it. Ciao!
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@dispensarysupport I definitely agree there’s a placebo component with some of this stuff, especially when people start 4 things at once and somehow know exactly which one changed their life
. But I’m probably a little less skeptical overall.GLP-1s are obviously in a different league evidence-wise, but KLOW and Cartalax have given me changes noticeable enough that I personally can’t throw them into the “whatever” category. MOTS-C is newer for me, and I’m still figuring that one out, but the cardio/energy side has definitely caught my attention.
That’s actually why I like hearing from people who’ve been messing with these for a couple years though. Separating the genuinely useful stuff from the expensive placebo is half the battle

Juliano546 said:
@dispensarysupport I definitely agree there’s a placebo component with some of this stuff, especially when people start 4 things at once and somehow know exactly which one changed their life
. But I’m probably a little less skeptical overall.GLP-1s are obviously in a different league evidence-wise, but KLOW and Cartalax have given me changes noticeable enough that I personally can’t throw them into the “whatever” category. MOTS-C is newer for me, and I’m still figuring that one out, but the cardio/energy side has definitely caught my attention.
That’s actually why I like hearing from people who’ve been messing with these for a couple years though. Separating the genuinely useful stuff from the expensive placebo is half the battle

It's the GHK-cu.
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@dispensarysupport I agree across the board.
Many are part of the hype train but largely placebo. I do think there is some validity to the healing compounds. BPC/TB. Hear overwhelming anecdotal evidence toward the addition of KPV. I’m personally quickly becoming a believer in MOTS.
GLPs are a miracle drug. Optimized test and IGF complete the Holy Trinity.
Can I ask, why did you go from Tesa/Ipa to HGH. Are you done with the former or do you alternate?
@dispensarysupport I agree across the board.
Many are part of the hype train but largely placebo. I do think there is some validity to the healing compounds. BPC/TB. Hear overwhelming anecdotal evidence toward the addition of KPV. I’m personally quickly becoming a believer in MOTS.
GLPs are a miracle drug. Optimized test and IGF complete the Holy Trinity.
Can I ask, why did you go from Tesa/Ipa to HGH. Are you done with the former or do you alternate?
I honestly just gave the wife the Tesa/IPA and went to try the GH and liked it so just stuck with it. Literally have 8 kits that just left china on their way to me now with 8 kits of MS40. That should cover me for awhile.
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Been messing with a ton of them for about 2.5yrs now. I believe most are largely placebo and people just wanting to have more out of things.
My working hypothesis is that they are not so much placebos as they instigate or catalyze the lifestyle change that result in the desired outcomes.
Most people probably take too many (not unique to peptides), but hopefully settle into a stack like yours.
A lot of the reading I’ve done supports the ‘fix your sleep and your diet and 99% of your problems go away’ hypothesis. But there is still a place for peps, and used correctly, they’re amazing.
ResearchCat said:
Been messing with a ton of them for about 2.5yrs now. I believe most are largely placebo and people just wanting to have more out of things.
My working hypothesis is that they are not so much placebos as they instigate or catalyze the lifestyle change that result in the desired outcomes.
Most people probably take too many (not unique to peptides), but hopefully settle into a stack like yours.
A lot of the reading I’ve done supports the ‘fix your sleep and your diet and 99% of your problems go away’ hypothesis. But there is still a place for peps, and used correctly, they’re amazing.
I could not agree more with pretty much all of that. Cheers
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