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Eloralintide

Scheduled Pinned Locked Moved Peptide Discussion
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247 Posts 40 Posters 10.8k Views 7 Watching
Eloralintide
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  • mmpM mmp

    @Randy πŸ˜† πŸ˜† πŸ˜†
    Now 11.2 makes sense.

    RandyR Offline
    RandyR Offline
    Randy
    wrote last edited by
    #12

    @mmp if you know you know

    "If it doesnt come in a needle. It doesn't work"

    1 Reply Last reply
    0
    • J jennn

      @Randy Have you ran Cagri already? I’d be interested to see how they compare, especially with all the talk about the secondary structure of this peptide being important for function. Printing a preptide is one thing, but I don’t know what goes into determination of the secondary structure. Seems like big pharma wants to throw a monkey wrench into peptide manufacturing. Heh

      RandyR Offline
      RandyR Offline
      Randy
      wrote last edited by
      #13

      @jennn Yeah. It's good. But it could always be better. Anything over 1.5mg and i start to feel meh for a day or two after dosing.

      As far as the secondary structure this is the test you speak of https://verify.janoshik.com/tests/235512-Eloralintide_10mg_Transparent_Purple_Silver_K5Z37119GH7P

      Unless they run this test ill just assume they threw cagri and tirz in a bottle...or selank like ERP did with their Elora.

      "If it doesnt come in a needle. It doesn't work"

      J 1 Reply Last reply
      3
      • SpaceGhostS SpaceGhost

        No wonder the filters aren’t up in the store! 🀠

        RandyR Offline
        RandyR Offline
        Randy
        wrote last edited by
        #14

        @SpaceGhost next week πŸ™‚

        "If it doesnt come in a needle. It doesn't work"

        1 Reply Last reply
        0
        • RandyR Randy

          @jennn Yeah. It's good. But it could always be better. Anything over 1.5mg and i start to feel meh for a day or two after dosing.

          As far as the secondary structure this is the test you speak of https://verify.janoshik.com/tests/235512-Eloralintide_10mg_Transparent_Purple_Silver_K5Z37119GH7P

          Unless they run this test ill just assume they threw cagri and tirz in a bottle...or selank like ERP did with their Elora.

          J Offline
          J Offline
          jennn
          wrote last edited by
          #15

          @Randy omg I had no idea they could test for that! That’s awesome! I shoulda known you’d have planned for that. You don’t half ass this stuff. πŸ™‚

          RandyR 1 Reply Last reply
          0
          • J jennn

            @Randy omg I had no idea they could test for that! That’s awesome! I shoulda known you’d have planned for that. You don’t half ass this stuff. πŸ™‚

            RandyR Offline
            RandyR Offline
            Randy
            wrote last edited by
            #16

            @jennn ive ordered from uther and a few others. all results were shizz thus far. leave it to nexaph to deliver (extremely expensive though)

            "If it doesnt come in a needle. It doesn't work"

            S M 2 Replies Last reply
            2
            • S Offline
              S Offline
              Shifted
              wrote last edited by
              #17

              Yeah, wow. Over $600 for a kit of 10mg. Definitely going to wait on a sale.

              B 1 Reply Last reply
              0
              • D Offline
                D Offline
                denti
                wrote last edited by
                #18

                @randy What dose/protocol you going to do with Elora?

                RandyR 1 Reply Last reply
                0
                • WisGal64W Offline
                  WisGal64W Offline
                  WisGal64
                  wrote last edited by
                  #19

                  I started this week 😁

                  β€œNot a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

                  RandyR 1 Reply Last reply
                  0
                  • RandyR Randy

                    Ok...whos coming with me?

                    3e0b9dfd-ffe6-4610-b8a0-9c42f07b69ec.jpeg

                    J Offline
                    J Offline
                    JtCjEfF
                    wrote last edited by
                    #20

                    @Randy SUPER tempted!

                    1 Reply Last reply
                    0
                    • D denti

                      @randy What dose/protocol you going to do with Elora?

                      RandyR Offline
                      RandyR Offline
                      Randy
                      wrote last edited by
                      #21

                      @denti probably half a milligram. the half life of this one scurrrs me.

                      "If it doesnt come in a needle. It doesn't work"

                      1 Reply Last reply
                      1
                      • WisGal64W WisGal64

                        I started this week 😁

                        RandyR Offline
                        RandyR Offline
                        Randy
                        wrote last edited by
                        #22

                        @WisGal64 is it the best thing ever or?

                        "If it doesnt come in a needle. It doesn't work"

                        1 Reply Last reply
                        0
                        • WisGal64W Offline
                          WisGal64W Offline
                          WisGal64
                          wrote last edited by WisGal64
                          #23

                          @randy I’m not sure yet, started at .5 but so far no fatigue or nausea like I had with Cag

                          β€œNot a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

                          1 Reply Last reply
                          1
                          • RandyR Offline
                            RandyR Offline
                            Randy
                            wrote last edited by Randy
                            #24

                            I guess i start tomorrow πŸ€“

                            @wisgal64 did you flush out cag first?

                            "If it doesnt come in a needle. It doesn't work"

                            WisGal64W S 2 Replies Last reply
                            4
                            • RandyR Offline
                              RandyR Offline
                              Randy
                              wrote last edited by Randy
                              #25

                              BLANK ELORA LABEL.png
                              24082.png
                              Just in case anyone wants a label for their pens πŸ™‚

                              "If it doesnt come in a needle. It doesn't work"

                              1 Reply Last reply
                              6
                              • RandyR Randy

                                I guess i start tomorrow πŸ€“

                                @wisgal64 did you flush out cag first?

                                WisGal64W Offline
                                WisGal64W Offline
                                WisGal64
                                wrote last edited by
                                #26

                                @Randy said:

                                I guess i start tomorrow πŸ€“

                                @wisgal64 did you flush out cag first?

                                Ohhh yeah, I didn't last a month on it. It's been 2 months since.
                                I did start back on Tirz last week, but decided I'll drop it going forward for the time being so I can give the Elo time to do it's thing.

                                The ENLIGHTEN‑4 clinical trial includes targeting OA so this one is right up my alley πŸ™‚ Keeping fingers crossed for good results πŸ™‚

                                β€œNot a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.”

                                1 Reply Last reply
                                1
                                • RandyR Randy

                                  I guess i start tomorrow πŸ€“

                                  @wisgal64 did you flush out cag first?

                                  S Offline
                                  S Offline
                                  Stevepep
                                  wrote last edited by
                                  #27

                                  @Randy let us know I am waiting to start

                                  RandyR 1 Reply Last reply
                                  0
                                  • J Offline
                                    J Offline
                                    JtCjEfF
                                    wrote last edited by JtCjEfF
                                    #28

                                    Ive been looking into this, and it may be the perfect pairing to reta for me to help bring down the RHR issue I have with reta. I am finding claims that the amylin agonists lower heart rate.

                                    Edit: I found some data, if its true.

                                    Heart Rate Reductions by DoseAccording to findings published from its early clinical evaluation, the mean changes in pulse rate from baseline after 12 weeks of treatment are:
                                    3 mg dose: Decreased by 7.1 bpm
                                    6 mg dose: Decreased by 8.3 bpm
                                    12 mg dose: Decreased by 14.4 bpm
                                    Placebo group: Decreased by 3.4 bpm

                                    These reductions are sustained, begin as early as the first week of treatment, and have not been associated with symptomatic bradycardia (abnormally or dangerously slow heart rate) in trials.

                                    M D 2 Replies Last reply
                                    1
                                    • J JtCjEfF

                                      Ive been looking into this, and it may be the perfect pairing to reta for me to help bring down the RHR issue I have with reta. I am finding claims that the amylin agonists lower heart rate.

                                      Edit: I found some data, if its true.

                                      Heart Rate Reductions by DoseAccording to findings published from its early clinical evaluation, the mean changes in pulse rate from baseline after 12 weeks of treatment are:
                                      3 mg dose: Decreased by 7.1 bpm
                                      6 mg dose: Decreased by 8.3 bpm
                                      12 mg dose: Decreased by 14.4 bpm
                                      Placebo group: Decreased by 3.4 bpm

                                      These reductions are sustained, begin as early as the first week of treatment, and have not been associated with symptomatic bradycardia (abnormally or dangerously slow heart rate) in trials.

                                      M Offline
                                      M Offline
                                      MikeMiranda
                                      wrote last edited by
                                      #29

                                      @JtCjEfF said:

                                      Ive been looking into this, and it may be the perfect pairing to reta for me to help bring down the RHR issue I have with reta. I am finding claims that the amylin agonists lower heart rate.

                                      Edit: I found some data, if its true.

                                      Heart Rate Reductions by DoseAccording to findings published from its early clinical evaluation, the mean changes in pulse rate from baseline after 12 weeks of treatment are:
                                      3 mg dose: Decreased by 7.1 bpm
                                      6 mg dose: Decreased by 8.3 bpm
                                      12 mg dose: Decreased by 14.4 bpm
                                      Placebo group: Decreased by 3.4 bpm

                                      These reductions are sustained, begin as early as the first week of treatment, and have not been associated with symptomatic bradycardia (abnormally or dangerously slow heart rate) in trials.

                                      Any links to this data?

                                      J 1 Reply Last reply
                                      0
                                      • S Stevepep

                                        @Randy let us know I am waiting to start

                                        RandyR Offline
                                        RandyR Offline
                                        Randy
                                        wrote last edited by
                                        #30

                                        @Stevepep im just gonna rip one mg tonight. Its been a week since ive blasted cag so this is very plausible ill regret this.

                                        Someone's got to do the research.

                                        "If it doesnt come in a needle. It doesn't work"

                                        ResearchCatR D 2 Replies Last reply
                                        11
                                        • M MikeMiranda

                                          @JtCjEfF said:

                                          Ive been looking into this, and it may be the perfect pairing to reta for me to help bring down the RHR issue I have with reta. I am finding claims that the amylin agonists lower heart rate.

                                          Edit: I found some data, if its true.

                                          Heart Rate Reductions by DoseAccording to findings published from its early clinical evaluation, the mean changes in pulse rate from baseline after 12 weeks of treatment are:
                                          3 mg dose: Decreased by 7.1 bpm
                                          6 mg dose: Decreased by 8.3 bpm
                                          12 mg dose: Decreased by 14.4 bpm
                                          Placebo group: Decreased by 3.4 bpm

                                          These reductions are sustained, begin as early as the first week of treatment, and have not been associated with symptomatic bradycardia (abnormally or dangerously slow heart rate) in trials.

                                          Any links to this data?

                                          J Offline
                                          J Offline
                                          JtCjEfF
                                          wrote last edited by
                                          #31

                                          @MikeMiranda

                                          https://pmc.ncbi.nlm.nih.gov/articles/PMC12992164/#dom70439-sec-0012

                                          3.2.3 Vital Signs

                                          1 Reply Last reply
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