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Eloralintide

Scheduled Pinned Locked Moved Peptide Discussion
researching
247 Posts 40 Posters 10.8k Views 7 Watching
Eloralintide
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  • J jennn

    @Randy Have you ran Cagri already? Iโ€™d be interested to see how they compare, especially with all the talk about the secondary structure of this peptide being important for function. Printing a preptide is one thing, but I donโ€™t know what goes into determination of the secondary structure. Seems like big pharma wants to throw a monkey wrench into peptide manufacturing. Heh

    RandyR Offline
    RandyR Offline
    Randy
    wrote last edited by
    #13

    @jennn Yeah. It's good. But it could always be better. Anything over 1.5mg and i start to feel meh for a day or two after dosing.

    As far as the secondary structure this is the test you speak of https://verify.janoshik.com/tests/235512-Eloralintide_10mg_Transparent_Purple_Silver_K5Z37119GH7P

    Unless they run this test ill just assume they threw cagri and tirz in a bottle...or selank like ERP did with their Elora.

    "If it doesnt come in a needle. It doesn't work"

    J 1 Reply Last reply
    3
    • SpaceGhostS SpaceGhost

      No wonder the filters arenโ€™t up in the store! ๐Ÿค 

      RandyR Offline
      RandyR Offline
      Randy
      wrote last edited by
      #14

      @SpaceGhost next week ๐Ÿ™‚

      "If it doesnt come in a needle. It doesn't work"

      1 Reply Last reply
      0
      • RandyR Randy

        @jennn Yeah. It's good. But it could always be better. Anything over 1.5mg and i start to feel meh for a day or two after dosing.

        As far as the secondary structure this is the test you speak of https://verify.janoshik.com/tests/235512-Eloralintide_10mg_Transparent_Purple_Silver_K5Z37119GH7P

        Unless they run this test ill just assume they threw cagri and tirz in a bottle...or selank like ERP did with their Elora.

        J Offline
        J Offline
        jennn
        wrote last edited by
        #15

        @Randy omg I had no idea they could test for that! Thatโ€™s awesome! I shoulda known youโ€™d have planned for that. You donโ€™t half ass this stuff. ๐Ÿ™‚

        RandyR 1 Reply Last reply
        0
        • J jennn

          @Randy omg I had no idea they could test for that! Thatโ€™s awesome! I shoulda known youโ€™d have planned for that. You donโ€™t half ass this stuff. ๐Ÿ™‚

          RandyR Offline
          RandyR Offline
          Randy
          wrote last edited by
          #16

          @jennn ive ordered from uther and a few others. all results were shizz thus far. leave it to nexaph to deliver (extremely expensive though)

          "If it doesnt come in a needle. It doesn't work"

          S M 2 Replies Last reply
          2
          • S Offline
            S Offline
            Shifted
            wrote last edited by
            #17

            Yeah, wow. Over $600 for a kit of 10mg. Definitely going to wait on a sale.

            B 1 Reply Last reply
            0
            • D Offline
              D Offline
              denti
              wrote last edited by
              #18

              @randy What dose/protocol you going to do with Elora?

              RandyR 1 Reply Last reply
              0
              • WisGal64W Offline
                WisGal64W Offline
                WisGal64
                wrote last edited by
                #19

                I started this week ๐Ÿ˜

                โ€œNot a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.โ€

                RandyR 1 Reply Last reply
                0
                • RandyR Randy

                  Ok...whos coming with me?

                  3e0b9dfd-ffe6-4610-b8a0-9c42f07b69ec.jpeg

                  J Online
                  J Online
                  JtCjEfF
                  wrote last edited by
                  #20

                  @Randy SUPER tempted!

                  1 Reply Last reply
                  0
                  • D denti

                    @randy What dose/protocol you going to do with Elora?

                    RandyR Offline
                    RandyR Offline
                    Randy
                    wrote last edited by
                    #21

                    @denti probably half a milligram. the half life of this one scurrrs me.

                    "If it doesnt come in a needle. It doesn't work"

                    1 Reply Last reply
                    1
                    • WisGal64W WisGal64

                      I started this week ๐Ÿ˜

                      RandyR Offline
                      RandyR Offline
                      Randy
                      wrote last edited by
                      #22

                      @WisGal64 is it the best thing ever or?

                      "If it doesnt come in a needle. It doesn't work"

                      1 Reply Last reply
                      0
                      • WisGal64W Offline
                        WisGal64W Offline
                        WisGal64
                        wrote last edited by WisGal64
                        #23

                        @randy Iโ€™m not sure yet, started at .5 but so far no fatigue or nausea like I had with Cag

                        โ€œNot a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.โ€

                        1 Reply Last reply
                        1
                        • RandyR Offline
                          RandyR Offline
                          Randy
                          wrote last edited by Randy
                          #24

                          I guess i start tomorrow ๐Ÿค“

                          @wisgal64 did you flush out cag first?

                          "If it doesnt come in a needle. It doesn't work"

                          WisGal64W S 2 Replies Last reply
                          4
                          • RandyR Offline
                            RandyR Offline
                            Randy
                            wrote last edited by Randy
                            #25

                            BLANK ELORA LABEL.png
                            24082.png
                            Just in case anyone wants a label for their pens ๐Ÿ™‚

                            "If it doesnt come in a needle. It doesn't work"

                            1 Reply Last reply
                            6
                            • RandyR Randy

                              I guess i start tomorrow ๐Ÿค“

                              @wisgal64 did you flush out cag first?

                              WisGal64W Offline
                              WisGal64W Offline
                              WisGal64
                              wrote last edited by
                              #26

                              @Randy said:

                              I guess i start tomorrow ๐Ÿค“

                              @wisgal64 did you flush out cag first?

                              Ohhh yeah, I didn't last a month on it. It's been 2 months since.
                              I did start back on Tirz last week, but decided I'll drop it going forward for the time being so I can give the Elo time to do it's thing.

                              The ENLIGHTENโ€‘4 clinical trial includes targeting OA so this one is right up my alley ๐Ÿ™‚ Keeping fingers crossed for good results ๐Ÿ™‚

                              โ€œNot a guru, not a chemist-just here trying to keep my receptors AND my sanity responsive.โ€

                              1 Reply Last reply
                              1
                              • RandyR Randy

                                I guess i start tomorrow ๐Ÿค“

                                @wisgal64 did you flush out cag first?

                                S Offline
                                S Offline
                                Stevepep
                                wrote last edited by
                                #27

                                @Randy let us know I am waiting to start

                                RandyR 1 Reply Last reply
                                0
                                • J Online
                                  J Online
                                  JtCjEfF
                                  wrote last edited by JtCjEfF
                                  #28

                                  Ive been looking into this, and it may be the perfect pairing to reta for me to help bring down the RHR issue I have with reta. I am finding claims that the amylin agonists lower heart rate.

                                  Edit: I found some data, if its true.

                                  Heart Rate Reductions by DoseAccording to findings published from its early clinical evaluation, the mean changes in pulse rate from baseline after 12 weeks of treatment are:
                                  3 mg dose: Decreased by 7.1 bpm
                                  6 mg dose: Decreased by 8.3 bpm
                                  12 mg dose: Decreased by 14.4 bpm
                                  Placebo group: Decreased by 3.4 bpm

                                  These reductions are sustained, begin as early as the first week of treatment, and have not been associated with symptomatic bradycardia (abnormally or dangerously slow heart rate) in trials.

                                  M D 2 Replies Last reply
                                  1
                                  • J JtCjEfF

                                    Ive been looking into this, and it may be the perfect pairing to reta for me to help bring down the RHR issue I have with reta. I am finding claims that the amylin agonists lower heart rate.

                                    Edit: I found some data, if its true.

                                    Heart Rate Reductions by DoseAccording to findings published from its early clinical evaluation, the mean changes in pulse rate from baseline after 12 weeks of treatment are:
                                    3 mg dose: Decreased by 7.1 bpm
                                    6 mg dose: Decreased by 8.3 bpm
                                    12 mg dose: Decreased by 14.4 bpm
                                    Placebo group: Decreased by 3.4 bpm

                                    These reductions are sustained, begin as early as the first week of treatment, and have not been associated with symptomatic bradycardia (abnormally or dangerously slow heart rate) in trials.

                                    M Online
                                    M Online
                                    MikeMiranda
                                    wrote last edited by
                                    #29

                                    @JtCjEfF said:

                                    Ive been looking into this, and it may be the perfect pairing to reta for me to help bring down the RHR issue I have with reta. I am finding claims that the amylin agonists lower heart rate.

                                    Edit: I found some data, if its true.

                                    Heart Rate Reductions by DoseAccording to findings published from its early clinical evaluation, the mean changes in pulse rate from baseline after 12 weeks of treatment are:
                                    3 mg dose: Decreased by 7.1 bpm
                                    6 mg dose: Decreased by 8.3 bpm
                                    12 mg dose: Decreased by 14.4 bpm
                                    Placebo group: Decreased by 3.4 bpm

                                    These reductions are sustained, begin as early as the first week of treatment, and have not been associated with symptomatic bradycardia (abnormally or dangerously slow heart rate) in trials.

                                    Any links to this data?

                                    J 1 Reply Last reply
                                    0
                                    • S Stevepep

                                      @Randy let us know I am waiting to start

                                      RandyR Offline
                                      RandyR Offline
                                      Randy
                                      wrote last edited by
                                      #30

                                      @Stevepep im just gonna rip one mg tonight. Its been a week since ive blasted cag so this is very plausible ill regret this.

                                      Someone's got to do the research.

                                      "If it doesnt come in a needle. It doesn't work"

                                      ResearchCatR D 2 Replies Last reply
                                      11
                                      • M MikeMiranda

                                        @JtCjEfF said:

                                        Ive been looking into this, and it may be the perfect pairing to reta for me to help bring down the RHR issue I have with reta. I am finding claims that the amylin agonists lower heart rate.

                                        Edit: I found some data, if its true.

                                        Heart Rate Reductions by DoseAccording to findings published from its early clinical evaluation, the mean changes in pulse rate from baseline after 12 weeks of treatment are:
                                        3 mg dose: Decreased by 7.1 bpm
                                        6 mg dose: Decreased by 8.3 bpm
                                        12 mg dose: Decreased by 14.4 bpm
                                        Placebo group: Decreased by 3.4 bpm

                                        These reductions are sustained, begin as early as the first week of treatment, and have not been associated with symptomatic bradycardia (abnormally or dangerously slow heart rate) in trials.

                                        Any links to this data?

                                        J Online
                                        J Online
                                        JtCjEfF
                                        wrote last edited by
                                        #31

                                        @MikeMiranda

                                        https://pmc.ncbi.nlm.nih.gov/articles/PMC12992164/#dom70439-sec-0012

                                        3.2.3 Vital Signs

                                        1 Reply Last reply
                                        1
                                        • RandyR Randy

                                          @Stevepep im just gonna rip one mg tonight. Its been a week since ive blasted cag so this is very plausible ill regret this.

                                          Someone's got to do the research.

                                          ResearchCatR Offline
                                          ResearchCatR Offline
                                          ResearchCat
                                          wrote last edited by
                                          #32

                                          @Randy I am feeling like I am being pulled into an entirely unnecessary research project. ๐Ÿคฃ

                                          Yeah, well, Iโ€™m just here for the research, man. - The Dude

                                          If I havenโ€™t liked your post, no offense. I have exceeded my daily allowance.

                                          RandyR 1 Reply Last reply
                                          6

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