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Epitalon Subcutaneous Research Dosing Protocol

Scheduled Pinned Locked Moved Peptide Discussion
researchingepitalon-epithalon
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  • RandyR Randy

    we just parterned with a testing company thats dirt cheap https://peptidecritic.com/lab-tests/ulta-bloodwork

    Im on the road so i have to check what theyre calling the telomere length test but you absolutely should do it before and after on your rat.

    D Offline
    D Offline
    diegoc
    wrote last edited by
    #20

    @Randy hey Jeff, i do alot of BW, once a month.

    The typical stuff when checking test, Hemocratic, ferritin, IGF

    Whats the best option to choose in your vendor.

    Thanks

    RandyR 1 Reply Last reply
    0
    • D diegoc

      @Randy hey Jeff, i do alot of BW, once a month.

      The typical stuff when checking test, Hemocratic, ferritin, IGF

      Whats the best option to choose in your vendor.

      Thanks

      RandyR Offline
      RandyR Offline
      Randy
      wrote last edited by
      #21

      @diegoc i just pick and choose what my veterinarian tells me to depending on what im researching. I wont pretend to be some expert on reading bloodwork or panels. There are much better experts on the subject.

      "If it doesnt come in a needle. It doesn't work"

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      • ResearchCatR Offline
        ResearchCatR Offline
        ResearchCat
        wrote last edited by
        #22

        Tbh, I am suffering analysis paralysis choosing between vendors. I reckon I will pick one, but I like that function supposedly tells you what it means and can refer you.

        Sadly, the two YouTube personalities I’ve reached out to who have related businesses in this space are much better at making videos than running a business.

        Yeah, well, I’m just here for the research, man. - The Dude

        If I haven’t liked your post, no offense. I have exceeded my daily allowance.

        D 1 Reply Last reply
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        • ResearchCatR ResearchCat

          Tbh, I am suffering analysis paralysis choosing between vendors. I reckon I will pick one, but I like that function supposedly tells you what it means and can refer you.

          Sadly, the two YouTube personalities I’ve reached out to who have related businesses in this space are much better at making videos than running a business.

          D Offline
          D Offline
          diegoc
          wrote last edited by
          #23

          @ResearchCat hey buddy, listen that is common in us men, but just do it.

          However document your goals.

          Do your research on Frequency and Dosing

          As for the vendors, man there are alot of good ones that are pretty trust worthy.

          Mile High are good and add the peptide critic discount

          1 Reply Last reply
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          • P Offline
            P Offline
            PeptidePreston
            wrote last edited by PeptidePreston
            #24

            @randy @researchcat @diegoc I've stacked Epi & Pinealon for 20 days previously as a suggestion but didn't really know much about it. A few months prior I researched a 30 day cycle of Pinealon. Pinealon was fantastic for improved sleep, energy, mood, etc.

            I've seen suggestions only to research Epi or Pinealon maybe 2-3 times a year. I know they can be used together, but what if you wanted to research and get a benefit from them separately? If someone has any information or can point me in the right direction that would be much appreciated. My rat has central sleep apnea and gets less than 3 hrs of real sleep each night, even with being 33, 6ft, 180 lbs, active & healthy.

            Ps. I've researched DSIP and the only thing it really did was more intense dreams.

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            • ResearchCatR Offline
              ResearchCatR Offline
              ResearchCat
              wrote last edited by ResearchCat
              #25

              My epitalon research was specifically focused on longevity, so I can’t speak to sleep changes except to say that I have not noticed changes due to this or any other peptide research. My sleep is generally better, but I have also stopped drinking alcohol (mostly) and am going to bed earlier and cutting off digital garbage beforehand, making it hard to attribute.

              Most of the longevity focused research in humans indicates running a 10-20 day cycle once or twice a year, not constant maintenance. Sorry I can’t be much help for your interest.

              Edit: If I am being honest, quitting a p2w mobile game and associated reduced stress is probably the biggest contributor to my increased sleep quality. (It also frees up lots of money for research. 😉 )

              Yeah, well, I’m just here for the research, man. - The Dude

              If I haven’t liked your post, no offense. I have exceeded my daily allowance.

              1 Reply Last reply
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              • RandyR Offline
                RandyR Offline
                Randy
                wrote last edited by
                #26

                ...have you tried pinealon?

                I discovered that one a few years back. Prior to that i needed a handful of melatonin gummies or Ambien to sleep. I haven't needed it since.

                "If it doesnt come in a needle. It doesn't work"

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                • P PeptideCritic moved this topic from Skin & Anti-Aging on
                • D Offline
                  D Offline
                  diegoc
                  wrote last edited by
                  #27

                  @randy hey Jeff, I saw the latest video on mixing Epitalon in several vials and you mentioned that Randy does Thymalin after the Epitalon protocol.

                  Do you have any info on that.

                  Thanks

                  1 Reply Last reply
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                  • P PeptideEd

                    @researchcat I can report that 2mg per day has been dramatically noticeable for me (in a very positive way) in terms of improved sleep. That said the only downside I've ever heard anyone report about the higher dosages is that it made them a little drowsy during the following day.

                    afkar7A Offline
                    afkar7A Offline
                    afkar7
                    wrote last edited by
                    #28

                    @PeptideEd said in Epitalon Subcutaneous Research Dosing Protocol:

                    @researchcat I can report that 2mg per day has been dramatically noticeable for me (in a very positive way) in terms of improved sleep. That said the only downside I've ever heard anyone report about the higher dosages is that it made them a little drowsy during the following day.

                    I plan on staring low like this also. At least for the first week and see where it goes.

                    P 1 Reply Last reply
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                    • vpepsV Online
                      vpepsV Online
                      vpeps
                      wrote last edited by
                      #29

                      For sure, even 100 mcg (yes, 0.1 mg) does affect me well. My Garmin watch shows the lowest stress during sleep I've seen in my life, and HRV goes up 30%.

                      attentiion is all you need

                      1 Reply Last reply
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                      • afkar7A afkar7

                        @PeptideEd said in Epitalon Subcutaneous Research Dosing Protocol:

                        @researchcat I can report that 2mg per day has been dramatically noticeable for me (in a very positive way) in terms of improved sleep. That said the only downside I've ever heard anyone report about the higher dosages is that it made them a little drowsy during the following day.

                        I plan on staring low like this also. At least for the first week and see where it goes.

                        P Offline
                        P Offline
                        PeptideEd
                        wrote last edited by
                        #30

                        @afkar7 One thing to remember though... when they say "take no more than 30 minutes before bed"... at least for me they meant it. I know I sometimes inject 'evening' peptides and then get distracted for a couple of hours before bed... for this one, really do make sure to just inject it and go straight to bed, go directly to bed, do not pass go, do not collect $200.

                        afkar7A 1 Reply Last reply
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                        • P PeptideEd

                          @afkar7 One thing to remember though... when they say "take no more than 30 minutes before bed"... at least for me they meant it. I know I sometimes inject 'evening' peptides and then get distracted for a couple of hours before bed... for this one, really do make sure to just inject it and go straight to bed, go directly to bed, do not pass go, do not collect $200.

                          afkar7A Offline
                          afkar7A Offline
                          afkar7
                          wrote last edited by
                          #31

                          @PeptideEd said in Epitalon Subcutaneous Research Dosing Protocol:

                          @afkar7 One thing to remember though... when they say "take no more than 30 minutes before bed"... at least for me they meant it. I know I sometimes inject 'evening' peptides and then get distracted for a couple of hours before bed... for this one, really do make sure to just inject it and go straight to bed, go directly to bed, do not pass go, do not collect $200.

                          Thanks, I appreciate the help.

                          1 Reply Last reply
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                          • RandyR Randy

                            For research use only. Not medical advice.

                            Overview

                            Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide studied for its potential effects on telomerase activation, cellular longevity, circadian rhythm normalization, and antioxidant regulation.
                            Research use typically involves short, intensive cycles rather than continuous long-term dosing.

                            Daily Dosing Protocol (Subcutaneous)

                            Standard Daily Range

                            10-20 mg once daily

                            The 10 mg daily dose is the most commonly cited range in aging and telomere-focused research.

                            Cycle Length Options

                            1. Standard Cycle (Most Common)

                            10 days

                            Daily dose: 10–20 mg

                            Researchers commonly run Epitalon as a short burst cycle, then take an extended break.

                            1. Extended Cycle (Alternative Model)

                            20 consecutive days

                            Daily dose: 10–20 mg

                            Used in some longevity-focused research models aiming for prolonged telomerase expression and circadian modulation.

                            Timing

                            Once daily, any time of day

                            Some researchers prefer evening dosing given its historical use for circadian rhythm correction, but timing is flexible.

                            Frequency & Cycling Pattern

                            Typical long-term patterns:

                            Annual or Semiannual Cycles

                            10–20 days on,

                            Several months off

                            In aging-related research, Epitalon is rarely used continuously — it is almost always delivered in short, high-intensity cycles, sometimes 1–4 times per year depending on the model.

                            Common Research Notes

                            Effects are subtle and accumulate gradually — often evaluated by sleep quality, recovery, or long-term biomarkers.

                            Some subjects report improvements in sleep consistency, recovery, and perceived vitality.

                            Because cycles are short, tolerability is usually excellent.

                            Epitalon is often paired with circadian-focused interventions or other mitochondrial peptides for synergistic longevity research.

                            pep_researcherP Offline
                            pep_researcherP Offline
                            pep_researcher
                            wrote last edited by
                            #32

                            @Randy Since Epithalon Dalton weight is under 400, can it be researched through nasal spray?

                            1 Reply Last reply
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                            • RandyR Randy

                              @ResearchCat yeah the whole thing. .5ml because its a stingy one

                              E Offline
                              E Offline
                              Eleanor
                              wrote last edited by
                              #33

                              @Randy said:

                              @ResearchCat yeah the whole thing. .5ml because its a stingy one

                              Oh great, another bee in the butt. Sigh...

                              Proud to be on a gubmint watch list

                              1 Reply Last reply
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