Epitalon Subcutaneous Research Dosing Protocol
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we just parterned with a testing company thats dirt cheap https://peptidecritic.com/lab-tests/ulta-bloodwork
Im on the road so i have to check what theyre calling the telomere length test but you absolutely should do it before and after on your rat.
@Randy I checked Ulta and the other lab providers and couldn’t find it. I did see some companies that do just this testing for 250-300. FlowFish, PSC, Spectra, a couple others.
I have a similar reconstitution question to what I asked in the SS-31 thread: for reconstituting 10mg vials where you are injecting basically the entire vial, is only using .200 ml or a little more ok rather than using 1ml+? I am just not sure if you would get the peptide to dissolve completely and/or there would be irritation or absorption issues due to the concentration.
Thanks.
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Just got my TruDiagnostic Advanced TruAge report results yesterday, includes telomeres. This is one month after Epithalon course, so better results to come in later this year, in theory:
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@Randy I checked Ulta and the other lab providers and couldn’t find it. I did see some companies that do just this testing for 250-300. FlowFish, PSC, Spectra, a couple others.
I have a similar reconstitution question to what I asked in the SS-31 thread: for reconstituting 10mg vials where you are injecting basically the entire vial, is only using .200 ml or a little more ok rather than using 1ml+? I am just not sure if you would get the peptide to dissolve completely and/or there would be irritation or absorption issues due to the concentration.
Thanks.
@ResearchCat yeah the whole thing. .5ml because its a stingy one
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we just parterned with a testing company thats dirt cheap https://peptidecritic.com/lab-tests/ulta-bloodwork
Im on the road so i have to check what theyre calling the telomere length test but you absolutely should do it before and after on your rat.
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@Randy hey Jeff, i do alot of BW, once a month.
The typical stuff when checking test, Hemocratic, ferritin, IGF
Whats the best option to choose in your vendor.
Thanks
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Tbh, I am suffering analysis paralysis choosing between vendors. I reckon I will pick one, but I like that function supposedly tells you what it means and can refer you.
Sadly, the two YouTube personalities I’ve reached out to who have related businesses in this space are much better at making videos than running a business.
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Tbh, I am suffering analysis paralysis choosing between vendors. I reckon I will pick one, but I like that function supposedly tells you what it means and can refer you.
Sadly, the two YouTube personalities I’ve reached out to who have related businesses in this space are much better at making videos than running a business.
@ResearchCat hey buddy, listen that is common in us men, but just do it.
However document your goals.
Do your research on Frequency and Dosing
As for the vendors, man there are alot of good ones that are pretty trust worthy.
Mile High are good and add the peptide critic discount
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@randy @researchcat @diegoc I've stacked Epi & Pinealon for 20 days previously as a suggestion but didn't really know much about it. A few months prior I researched a 30 day cycle of Pinealon. Pinealon was fantastic for improved sleep, energy, mood, etc.
I've seen suggestions only to research Epi or Pinealon maybe 2-3 times a year. I know they can be used together, but what if you wanted to research and get a benefit from them separately? If someone has any information or can point me in the right direction that would be much appreciated. My rat has central sleep apnea and gets less than 3 hrs of real sleep each night, even with being 33, 6ft, 180 lbs, active & healthy.
Ps. I've researched DSIP and the only thing it really did was more intense dreams.
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My epitalon research was specifically focused on longevity, so I can’t speak to sleep changes except to say that I have not noticed changes due to this or any other peptide research. My sleep is generally better, but I have also stopped drinking alcohol (mostly) and am going to bed earlier and cutting off digital garbage beforehand, making it hard to attribute.
Most of the longevity focused research in humans indicates running a 10-20 day cycle once or twice a year, not constant maintenance. Sorry I can’t be much help for your interest.
Edit: If I am being honest, quitting a p2w mobile game and associated reduced stress is probably the biggest contributor to my increased sleep quality. (It also frees up lots of money for research.
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P PeptideCritic moved this topic from Skin & Anti-Aging on
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@researchcat I can report that 2mg per day has been dramatically noticeable for me (in a very positive way) in terms of improved sleep. That said the only downside I've ever heard anyone report about the higher dosages is that it made them a little drowsy during the following day.
@PeptideEd said in Epitalon Subcutaneous Research Dosing Protocol:
@researchcat I can report that 2mg per day has been dramatically noticeable for me (in a very positive way) in terms of improved sleep. That said the only downside I've ever heard anyone report about the higher dosages is that it made them a little drowsy during the following day.
I plan on staring low like this also. At least for the first week and see where it goes.
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@PeptideEd said in Epitalon Subcutaneous Research Dosing Protocol:
@researchcat I can report that 2mg per day has been dramatically noticeable for me (in a very positive way) in terms of improved sleep. That said the only downside I've ever heard anyone report about the higher dosages is that it made them a little drowsy during the following day.
I plan on staring low like this also. At least for the first week and see where it goes.
@afkar7 One thing to remember though... when they say "take no more than 30 minutes before bed"... at least for me they meant it. I know I sometimes inject 'evening' peptides and then get distracted for a couple of hours before bed... for this one, really do make sure to just inject it and go straight to bed, go directly to bed, do not pass go, do not collect $200.
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@afkar7 One thing to remember though... when they say "take no more than 30 minutes before bed"... at least for me they meant it. I know I sometimes inject 'evening' peptides and then get distracted for a couple of hours before bed... for this one, really do make sure to just inject it and go straight to bed, go directly to bed, do not pass go, do not collect $200.
@PeptideEd said in Epitalon Subcutaneous Research Dosing Protocol:
@afkar7 One thing to remember though... when they say "take no more than 30 minutes before bed"... at least for me they meant it. I know I sometimes inject 'evening' peptides and then get distracted for a couple of hours before bed... for this one, really do make sure to just inject it and go straight to bed, go directly to bed, do not pass go, do not collect $200.
Thanks, I appreciate the help.
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For research use only. Not medical advice.
Overview
Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide studied for its potential effects on telomerase activation, cellular longevity, circadian rhythm normalization, and antioxidant regulation.
Research use typically involves short, intensive cycles rather than continuous long-term dosing.Daily Dosing Protocol (Subcutaneous)
Standard Daily Range
10-20 mg once daily
The 10 mg daily dose is the most commonly cited range in aging and telomere-focused research.
Cycle Length Options
- Standard Cycle (Most Common)
10 days
Daily dose: 10–20 mg
Researchers commonly run Epitalon as a short burst cycle, then take an extended break.
- Extended Cycle (Alternative Model)
20 consecutive days
Daily dose: 10–20 mg
Used in some longevity-focused research models aiming for prolonged telomerase expression and circadian modulation.
Timing
Once daily, any time of day
Some researchers prefer evening dosing given its historical use for circadian rhythm correction, but timing is flexible.
Frequency & Cycling Pattern
Typical long-term patterns:
Annual or Semiannual Cycles
10–20 days on,
Several months off
In aging-related research, Epitalon is rarely used continuously — it is almost always delivered in short, high-intensity cycles, sometimes 1–4 times per year depending on the model.
Common Research Notes
Effects are subtle and accumulate gradually — often evaluated by sleep quality, recovery, or long-term biomarkers.
Some subjects report improvements in sleep consistency, recovery, and perceived vitality.
Because cycles are short, tolerability is usually excellent.
Epitalon is often paired with circadian-focused interventions or other mitochondrial peptides for synergistic longevity research.
@Randy Since Epithalon Dalton weight is under 400, can it be researched through nasal spray?
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@ResearchCat yeah the whole thing. .5ml because its a stingy one
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