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5-Amino-1MQ Research

Scheduled Pinned Locked Moved Peptide Discussion
researchingnad5-amino-1mq
122 Posts 32 Posters 11.4k Views 4 Watching
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  • vpepsV Offline
    vpepsV Offline
    vpeps
    wrote last edited by vpeps
    #16

    I follow up with this question. You got me interested in 5-AMINO-1MQ, but I would prefer a capsule form, it seems like a lot of milligrams to inject. But does it work orally, and is it effective as 50 mg pill I can see for sale?

    Also, what would be a good source? I see it here for $129, I wonder if it can be trusted.

    attentiion is all you need

    P T D 3 Replies Last reply
    0
    • P Offline
      P Offline
      PeptideEd
      wrote last edited by
      #17

      @vpeptides I tend to use 0.6 ml of BAC water per 50 ml vial from Nexaph... so I'm injecting 60 units (still a lot). Do let us know your experience with capsules... I'd be curious wrt that option πŸ™‚

      1 Reply Last reply
      1
      • vpepsV vpeps

        I follow up with this question. You got me interested in 5-AMINO-1MQ, but I would prefer a capsule form, it seems like a lot of milligrams to inject. But does it work orally, and is it effective as 50 mg pill I can see for sale?

        Also, what would be a good source? I see it here for $129, I wonder if it can be trusted.

        P Offline
        P Offline
        PeptidePete
        wrote last edited by
        #18

        @vpeptides said:

        I follow up with this question. You got me interested in 5-AMINO-1MQ, but I would prefer a capsule form, it seems like a lot of milligrams to inject. But does it work orally, and is it effective as 50 mg pill I can see for sale?

        Also, what would be a good source? I see it here for $129, I wonder if it can be trusted.

        My research comes back that oral is "partially" bioavailble, specific percent unknown. As a pinned small molecule, it bypasses the liver ergo 100% (essentially) bioavailable. So even though I could do with fewer daily pins I choose not to compromise for convenience and I pin. No biggie.

        I bought 10 NEXAPH kits a while back.

        vpepsV 1 Reply Last reply
        0
        • P Offline
          P Offline
          PeptideEd
          wrote last edited by PeptideEd
          #19

          @peptidepete which batch?

          P 1 Reply Last reply
          0
          • P PeptidePete

            @vpeptides said:

            I follow up with this question. You got me interested in 5-AMINO-1MQ, but I would prefer a capsule form, it seems like a lot of milligrams to inject. But does it work orally, and is it effective as 50 mg pill I can see for sale?

            Also, what would be a good source? I see it here for $129, I wonder if it can be trusted.

            My research comes back that oral is "partially" bioavailble, specific percent unknown. As a pinned small molecule, it bypasses the liver ergo 100% (essentially) bioavailable. So even though I could do with fewer daily pins I choose not to compromise for convenience and I pin. No biggie.

            I bought 10 NEXAPH kits a while back.

            vpepsV Offline
            vpepsV Offline
            vpeps
            wrote last edited by
            #20

            @PeptidePete sources even only list it as "oral", so I guess, there should be something behind it?
            https://www.mypeptidematch.com/peptides/5-amino-1mq
            https://peptidebase.io/peptides/5-amino-1mq
            Also, there is a financial aspect, as even Nexaph has it over $200 for 50mg kit, while you can buy 60 500 mg capsules for this money.

            attentiion is all you need

            P 1 Reply Last reply
            0
            • P PeptideEd

              @peptidepete which batch?

              P Offline
              P Offline
              PeptidePete
              wrote last edited by
              #21

              @PeptideEd said:

              @peptidepete which batch?

              batch.jpg

              P 1 Reply Last reply
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              • vpepsV vpeps

                @PeptidePete sources even only list it as "oral", so I guess, there should be something behind it?
                https://www.mypeptidematch.com/peptides/5-amino-1mq
                https://peptidebase.io/peptides/5-amino-1mq
                Also, there is a financial aspect, as even Nexaph has it over $200 for 50mg kit, while you can buy 60 500 mg capsules for this money.

                P Offline
                P Offline
                PeptidePete
                wrote last edited by PeptidePete
                #22

                @vpeptides said:

                @PeptidePete sources even only list it as "oral", so I guess, there should be something behind it?
                https://www.mypeptidematch.com/peptides/5-amino-1mq
                https://peptidebase.io/peptides/5-amino-1mq
                Also, there is a financial aspect, as even Nexaph has it over $200 for 50mg kit, while you can buy 60 500 mg capsules for this money.

                Sources linked provide no scientifically backed proof of % bioavailability therefore no value calculation can be made.

                Pasted below from your link. Come on man? This is why I trust no one's research other than my own.

                comeon.jpg

                vpepsV 1 Reply Last reply
                0
                • P PeptidePete

                  @PeptideEd said:

                  @peptidepete which batch?

                  batch.jpg

                  P Offline
                  P Offline
                  PeptideEd
                  wrote last edited by
                  #23

                  @PeptidePete As fate would have it... I had that batch tested... came back clean, figured you'd like the additional peace of mind πŸ™‚

                  P J 2 Replies Last reply
                  2
                  • P PeptidePete

                    @vpeptides said:

                    @PeptidePete sources even only list it as "oral", so I guess, there should be something behind it?
                    https://www.mypeptidematch.com/peptides/5-amino-1mq
                    https://peptidebase.io/peptides/5-amino-1mq
                    Also, there is a financial aspect, as even Nexaph has it over $200 for 50mg kit, while you can buy 60 500 mg capsules for this money.

                    Sources linked provide no scientifically backed proof of % bioavailability therefore no value calculation can be made.

                    Pasted below from your link. Come on man? This is why I trust no one's research other than my own.

                    comeon.jpg

                    vpepsV Offline
                    vpepsV Offline
                    vpeps
                    wrote last edited by
                    #24

                    @PeptidePete Do you have better sources, please? I pasted those to demonstrate that "oral" route is mentioned first relative to this molecule, possibly from the available research, but the evidence is weak. No safety studies, no human studies that I see. I wonder if there is more data somewhere on it.

                    attentiion is all you need

                    P 1 Reply Last reply
                    1
                    • P PeptideEd

                      @PeptidePete As fate would have it... I had that batch tested... came back clean, figured you'd like the additional peace of mind πŸ™‚

                      P Offline
                      P Offline
                      PeptidePete
                      wrote last edited by
                      #25

                      PeptideEd said:

                      @PeptidePete As fate would have it... I had that batch tested... came back clean, figured you'd like the additional peace of mind πŸ™‚

                      You are a fine gentleman to share that with me...lol 😊 Thank you!

                      I'm sure the person from the other thread is going to post how I am killing myself with these kits because Finnrick said NEXAPH was pure poison. Or overfilled. Or something...hehe

                      I KNOW it's overfilled. I am THRILLED it is overfilled. Jeez Louise πŸ˜‚

                      1 Reply Last reply
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                      • vpepsV vpeps

                        @PeptidePete Do you have better sources, please? I pasted those to demonstrate that "oral" route is mentioned first relative to this molecule, possibly from the available research, but the evidence is weak. No safety studies, no human studies that I see. I wonder if there is more data somewhere on it.

                        P Offline
                        P Offline
                        PeptidePete
                        wrote last edited by
                        #26

                        @vpeptides said:

                        @PeptidePete Do you have better sources, please? I pasted those to demonstrate that "oral" route is mentioned first relative to this molecule, possibly from the available research, but the evidence is weak. No safety studies, no human studies that I see. I wonder if there is more data somewhere on it.

                        As alluded to up-thread I do not. That's the problem, we don't know absent a PK study. In lieu of that, I feel no choice but to err on the side of pinning it. Small molecules, as this is, are usually very amenable to 100% bioavailability with pinning. Bypassing the liver gives me more efficacy and keep my liver happier...lol πŸ˜‚

                        vpepsV 1 Reply Last reply
                        0
                        • P PeptidePete

                          @vpeptides said:

                          @PeptidePete Do you have better sources, please? I pasted those to demonstrate that "oral" route is mentioned first relative to this molecule, possibly from the available research, but the evidence is weak. No safety studies, no human studies that I see. I wonder if there is more data somewhere on it.

                          As alluded to up-thread I do not. That's the problem, we don't know absent a PK study. In lieu of that, I feel no choice but to err on the side of pinning it. Small molecules, as this is, are usually very amenable to 100% bioavailability with pinning. Bypassing the liver gives me more efficacy and keep my liver happier...lol πŸ˜‚

                          vpepsV Offline
                          vpepsV Offline
                          vpeps
                          wrote last edited by
                          #27

                          @PeptidePete it's tempting to try. The mechanistic argumentation is simple and understood. Some people would say the oral route is safer than subq, but what you say also a good argument. Isn't it the wild west of biomedicine? But there is no "Save"/"Reload" functionality in my body.

                          attentiion is all you need

                          1 Reply Last reply
                          0
                          • B Offline
                            B Offline
                            Bellaluca5675
                            wrote last edited by
                            #28

                            @randy I'm hearing you don't need to refrigerate 5 amino after you reconstitute, and then I hear it has to be in the fridge...what's your take on this?

                            B B RandyR 3 Replies Last reply
                            0
                            • vpepsV Offline
                              vpepsV Offline
                              vpeps
                              wrote last edited by
                              #29

                              As far as I know, NAD+ has minimal oral bioavailability. But it's good to hear 5-Amino-1MQ has an effect.

                              attentiion is all you need

                              1 Reply Last reply
                              0
                              • B Bellaluca5675

                                @randy I'm hearing you don't need to refrigerate 5 amino after you reconstitute, and then I hear it has to be in the fridge...what's your take on this?

                                B Offline
                                B Offline
                                brandenscheidecker
                                wrote last edited by
                                #30

                                @Bellaluca5675 there is a company called Heavy amino, they make their 5 amino from raw powder not from lipolyzed vials. Heavy does not recommend refrigerating their product. were lipolyzed vials from china or every other vendor do require refrigerating the vials after being reconst. hope this helps, I had a long discussion with Heavy before purchasing their product.

                                https://hvyresearch.com/

                                B P WisGal64W 3 Replies Last reply
                                1
                                • B Bellaluca5675

                                  @randy I'm hearing you don't need to refrigerate 5 amino after you reconstitute, and then I hear it has to be in the fridge...what's your take on this?

                                  B Offline
                                  B Offline
                                  Bellaluca5675
                                  wrote last edited by
                                  #31

                                  actually - from what i gathered, and to be specific - I was talking about 2000mg in a 20ml vial / what I've heard is its so concentrated that it gets chunky in the fridge. but 3ml/50mg vials should be refrigerated
                                  .

                                  1 Reply Last reply
                                  0
                                  • B brandenscheidecker

                                    @Bellaluca5675 there is a company called Heavy amino, they make their 5 amino from raw powder not from lipolyzed vials. Heavy does not recommend refrigerating their product. were lipolyzed vials from china or every other vendor do require refrigerating the vials after being reconst. hope this helps, I had a long discussion with Heavy before purchasing their product.

                                    https://hvyresearch.com/

                                    B Offline
                                    B Offline
                                    Bellaluca5675
                                    wrote last edited by
                                    #32

                                    @brandenscheidecker thankyou for the confirmation ! I'm actually getting a 2000mg 20ml vial from Heavy and that's what I've gathered from people who've used it as well. I was quite confused about the whole thing and thanks for clarifying!

                                    1 Reply Last reply
                                    2
                                    • B Bellaluca5675

                                      @randy I'm hearing you don't need to refrigerate 5 amino after you reconstitute, and then I hear it has to be in the fridge...what's your take on this?

                                      RandyR Online
                                      RandyR Online
                                      Randy
                                      wrote last edited by
                                      #33

                                      @Bellaluca5675 I dont have data on this but dont need to and should not are the terms here. If there is data that says you should not that somthing id be interested in. Do not need to? Why not if it doesnt hurt.

                                      "If it doesnt come in a needle. It doesn't work"

                                      1 Reply Last reply
                                      1
                                      • vpepsV vpeps

                                        I follow up with this question. You got me interested in 5-AMINO-1MQ, but I would prefer a capsule form, it seems like a lot of milligrams to inject. But does it work orally, and is it effective as 50 mg pill I can see for sale?

                                        Also, what would be a good source? I see it here for $129, I wonder if it can be trusted.

                                        T Offline
                                        T Offline
                                        thanks_enjoi
                                        wrote last edited by
                                        #34

                                        @vpeptides try chemyo I have had nothing but success with all of their offerings

                                        vpepsV 1 Reply Last reply
                                        1
                                        • B brandenscheidecker

                                          @Bellaluca5675 there is a company called Heavy amino, they make their 5 amino from raw powder not from lipolyzed vials. Heavy does not recommend refrigerating their product. were lipolyzed vials from china or every other vendor do require refrigerating the vials after being reconst. hope this helps, I had a long discussion with Heavy before purchasing their product.

                                          https://hvyresearch.com/

                                          P Offline
                                          P Offline
                                          PeptidePete
                                          wrote last edited by
                                          #35

                                          @brandenscheidecker said:

                                          @Bellaluca5675 there is a company called Heavy amino, they make their 5 amino from raw powder not from lipolyzed vials. Heavy does not recommend refrigerating their product. were lipolyzed vials from china or every other vendor do require refrigerating the vials after being reconst. hope this helps, I had a long discussion with Heavy before purchasing their product.

                                          https://hvyresearch.com/

                                          Makes sense: Small molecule vs peptide.

                                          The liquid product they offer is interesting for those of us indulging in no less than 25mg per pin, thanks for referencing!

                                          1 Reply Last reply
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