@markgroce thanks for sharing that video, 27:35 is where Peter talks about testing for heavy metals and endotoxins. I was interested to hear his claim that anything will test positive for heavy metals, and his thoughts on endotoxin testing.
@keithvanderhoeven I'm getting some signal that those levels are not concerning:
The United States Pharmacopeial Convention (USP) has established the daily parenteral limit for arsenic at 15 μg/day. Apparently the European standard is exactly the same.
If you plan to pin that reta over 4 doses, you'll get 0.13 μg in each dose. As I understand it, a serving rice in the US has 2-7 μg of arsenic.
Sources:
- https://www.usp.org/sites/default/files/usp/document/our-work/chemical-medicines/key-issues/232-40-35-1s.pdf, table 1, page 2.
- https://www.ema.europa.eu/en/documents/scientific-guideline/international-conference-harmonisation-technical-requirements-registration-pharmaceuticals-human-use-ich-q3d-elemental-impurities-step-5-revision-1_en.pdf, page 30
Oh, and I had no idea what "parenteral" means, so I had to look that up:
Administered or occurring elsewhere in the body than the mouth and alimentary canal.
Origin: para: "beside" + enteron "intestine" + al.
