I'm by no means comparing our situation to yours, just giving you information on what I and my wife have experienced. We both started glp's this year, her Reta, myself Tirz and also stack low dose reta for the liver. One thing that influences autoimmune response is chronic inflammation, which the drugs will reduce dramatically. I've always had psoriasis, mainly affecting my scalp, and gotten worse as I aged, mainly do to poor eating and shitty life choices . But since going on these and focusing on a clean anti inflammatory diet, shits gone. Maybe not gone, but haven't had as single flareup in 6 months and before that I lived by topical steroids. Took them everywhere with me. Not anymore. The wife has been dealing with osteoarthritis in her back and used prescription NSAIDs and radio frequency ablation for pain control. Today she needs none of it. Reta erased all the pain and inflammation. Both of these compounds are well known for there anti inflammatory effects, and Eli either is or has started a study on this specific outcome.