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Peptide Critic Community

Peptide Critic Community

  1. Randy the Rats Research Forum
  2. Supplies, Mixing & Storage
  3. Reconstitution Compatibility chart (grabbed from another group)

Reconstitution Compatibility chart (grabbed from another group)

Scheduled Pinned Locked Moved Supplies, Mixing & Storage
mixingreconstitutionbacteriostatic-water
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  • Snake PepskinS Snake Pepskin

    This might help someone. dbcc483e-7549-4e3a-8dcd-5028dad8ac0a-image.jpeg

    pep_researcherP Online
    pep_researcherP Online
    pep_researcher
    wrote on last edited by pep_researcher
    #21

    @Snake-Pepskin Not sure if saline BAC and Reta go together. I read multiple posts on Reddit. People tried reconstituting two Reta vials from the same batch using regular BAC and saline BAC — saline BAC turned it all gelly cloudy. Regular BAC was clear.

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    • Snake PepskinS Snake Pepskin

      @Stevepep

      I’m sure it’s an over cautious theoretical risk, but why not use standard BAC? I didn’t catch the discussion on it.

      pep_researcherP Online
      pep_researcherP Online
      pep_researcher
      wrote on last edited by
      #22

      @Snake-Pepskin said:

      @Stevepep

      I’m sure it’s an over cautious theoretical risk, but why not use standard BAC? I didn’t catch the discussion on it.

      Theory is saline BAC is isotonic, regular BAC is hypotonic. Isotonic liquid pins don't cause tissue stress that results in stinging or burning at research sites.

      Single dose Zep vials or pens have saline sterile water base.

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      • pep_researcherP pep_researcher

        @Snake-Pepskin said:

        @Stevepep

        I’m sure it’s an over cautious theoretical risk, but why not use standard BAC? I didn’t catch the discussion on it.

        Theory is saline BAC is isotonic, regular BAC is hypotonic. Isotonic liquid pins don't cause tissue stress that results in stinging or burning at research sites.

        Single dose Zep vials or pens have saline sterile water base.

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        Stevepep
        wrote on last edited by
        #23

        @pep_researcher the issue I guess is bacteria you have no protection if you use saline. Although I have contacts and it’s what we use to disinfect them. It’s all confusing

        E pep_researcherP 3 Replies Last reply
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        • S Stevepep

          @pep_researcher the issue I guess is bacteria you have no protection if you use saline. Although I have contacts and it’s what we use to disinfect them. It’s all confusing

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          Eleanor
          wrote on last edited by
          #24

          @Stevepep said:

          @pep_researcher the issue I guess is bacteria you have no protection if you use saline. Although I have contacts and it’s what we use to disinfect them. It’s all confusing

          The Pfizer NaCl and other salines I see also have 0.9% alcohol. Are you talking about something other than those?

          Proud to be on a gubmint watch list

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          • S Stevepep

            @pep_researcher the issue I guess is bacteria you have no protection if you use saline. Although I have contacts and it’s what we use to disinfect them. It’s all confusing

            pep_researcherP Online
            pep_researcherP Online
            pep_researcher
            wrote on last edited by
            #25

            @Stevepep @eleanor Answered. When one says "saline BAC" it's always with 0.9% benzyl alcohol.

            • Sterile water — no sodium chloride, no benzyl alcohol
            • Sterile saline — sterile water, 0.9% sodium chloride, no benzyl alcohol
            • Regular BAC — sterile water, 0.9% benzyl alcohol
            • Saline BAC — sterile water, 0.9% sodium chloride, 0.9% benzyl alcohol.
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            • S Stevepep

              @pep_researcher the issue I guess is bacteria you have no protection if you use saline. Although I have contacts and it’s what we use to disinfect them. It’s all confusing

              pep_researcherP Online
              pep_researcherP Online
              pep_researcher
              wrote on last edited by
              #26

              @Stevepep Further

              • Sterile Water, regular BAC — hypotonic, can cause tissue stress at research sites.
              • Sterile saline, saline BAC — isotonic, less tissue stress at research sites.

              Having said that one cannot just use saline BAC for everything to avoid research site sting, because different peps interact differently with sodium chloride.

              The posted chart is interesting although it may have some errors, like Reta + Saline BAC.

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              • pep_researcherP pep_researcher

                @Stevepep Further

                • Sterile Water, regular BAC — hypotonic, can cause tissue stress at research sites.
                • Sterile saline, saline BAC — isotonic, less tissue stress at research sites.

                Having said that one cannot just use saline BAC for everything to avoid research site sting, because different peps interact differently with sodium chloride.

                The posted chart is interesting although it may have some errors, like Reta + Saline BAC.

                S Offline
                S Offline
                Stevepep
                wrote on last edited by Stevepep
                #27

                @pep_researcher so is mots ok with bac saline and why don’t we use it for other peptides it’s far cheaper and if less irritating why not? Like maybe ghk-cu

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                • Snake PepskinS Snake Pepskin

                  This might help someone. dbcc483e-7549-4e3a-8dcd-5028dad8ac0a-image.jpeg

                  Stan DouglasS Offline
                  Stan DouglasS Offline
                  Stan Douglas
                  wrote on last edited by
                  #28

                  @Snake-Pepskin
                  HOL' UP
                  You're supposed to recon IGF with 100% AA?!?!?!?
                  My understanding it was like... 3 drops and the rest BW.

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                  • S Stevepep

                    @pep_researcher so is mots ok with bac saline and why don’t we use it for other peptides it’s far cheaper and if less irritating why not? Like maybe ghk-cu

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                    E Offline
                    Eleanor
                    wrote on last edited by Eleanor
                    #29

                    @Stevepep said:

                    @pep_researcher so is mots ok with bac saline and why don’t we use it for other peptides it’s far cheaper and if less irritating why not? Like maybe ghk-cu

                    Go to Mot-c Reconstitution at peptide protocols (dot) app

                    With regard to the GHK-cu, I don't think copper will like it but I haven't checked.

                    Proud to be on a gubmint watch list

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                    • pep_researcherP Online
                      pep_researcherP Online
                      pep_researcher
                      wrote on last edited by
                      #30

                      Yeah that chart isn't the source of truth. I wouldn't trust it.

                      Snake PepskinS 1 Reply Last reply
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                      • S Stevepep

                        @Snake-Pepskin I have had no issues with NAD+ and just use 3ml BAC. GHK-CU same for me that one just sucks

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                        T Offline
                        TBone
                        wrote on last edited by
                        #31

                        @Stevepep @snake-pepskin I also just started researching with 100mg NAD+ (Nexaph) with 3ml BAC and no issues at all.

                        Comfort is the worst addiction - Marcus Aurelius

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                        • pep_researcherP pep_researcher

                          Yeah that chart isn't the source of truth. I wouldn't trust it.

                          Snake PepskinS Offline
                          Snake PepskinS Offline
                          Snake Pepskin
                          wrote on last edited by
                          #32

                          @pep_researcher so let's correct it. What is your input/corrections?

                          “Knowledge is the ultimate power.
                          It’s not what you know that defines you, it’s that which you share, that defines you.”

                          pep_researcherP eurouserE 2 Replies Last reply
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                          • Snake PepskinS Snake Pepskin

                            @pep_researcher so let's correct it. What is your input/corrections?

                            pep_researcherP Online
                            pep_researcherP Online
                            pep_researcher
                            wrote on last edited by
                            #33

                            @Snake-Pepskin I don't have authoritative guide on which peps are compatible with saline BAC.

                            General thumb rule — most are compatible with regular BAC, some from those will be good with saline BAC too, some will not like sodium chloride and can gel.

                            I gave an example that I saw someone posting on Reddit that Reta didn't like saline BAC when they tried two Reta vials from the same batch. I asked an AI tool too and it said Reta will gel with saline BAC but tirzepatide and semaglutide will be fine with it.

                            Gist — that chart is NOT the ground truth. But I don't have the ground truth. Will do a chat session with multiple AI tools when I've extra time on hand and find out for popular peps. 🙂

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                            • Snake PepskinS Snake Pepskin

                              @pep_researcher so let's correct it. What is your input/corrections?

                              eurouserE Offline
                              eurouserE Offline
                              eurouser
                              Banned
                              wrote last edited by eurouser
                              #34

                              @Snake-Pepskin from my experience, AOD does not need acetic acid, been running it on my rat for months and i see no clumping and i def see results. So maybe instead of "required", the chart should say "optional" on that.

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                              • Snake PepskinS Offline
                                Snake PepskinS Offline
                                Snake Pepskin
                                wrote last edited by
                                #35

                                I agree, mostly. AOD is one of those temperamental compounds that I would always want to have AA at hand. Kisspeptin is another one that is very ph sensitive.

                                “Knowledge is the ultimate power.
                                It’s not what you know that defines you, it’s that which you share, that defines you.”

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                                • E Offline
                                  E Offline
                                  Eleanor
                                  wrote last edited by
                                  #36

                                  Both MOTS and SS31 favor saline BAC, although I reconned the last batch of SS31 w/regular & it's fine.

                                  Proud to be on a gubmint watch list

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                                  • kenhnsyK Offline
                                    kenhnsyK Offline
                                    kenhnsy
                                    wrote last edited by
                                    #37

                                    If the motivation of this topic is primarily to reduce stinging, I recommend a longer needle in a definite fatty area - butt cheeks. You will naturally diffuse it while driving to work. Ever since I went to 8mm Novafine (ceramic coated) needles for GHKCu, AOD, and NAD+, my girlfriend's big brown beaver reports very little stinging and no more welts. And this is simple to try.
                                    Yes. Beavers. They can talk.

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                                    • E Eleanor

                                      I would not use NaCl Bac on NAD+. Have no idea why it's stating "SALINE HEAVILY PREF"?

                                      J Offline
                                      J Offline
                                      JtCjEfF
                                      wrote last edited by
                                      #38

                                      @Eleanor Interestingly, in my first vial of buffered NAD I used NaCL bac water and it went fine without issues. I was thinking of this thread when i recon-ed my second vial and decided to use normal BAC water, both are Hospira.

                                      Dosing at the same dose daily, I am getting much more stinging and legit bruising now using the normal BAC water. I did a little research about it and the interweb gods tell me that it can be expected with normal BAC water with NAD.

                                      Not sure its true or not, but i can tell you my N=1 experience. Thought I would share.

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                                      • E Eleanor

                                        Both MOTS and SS31 favor saline BAC, although I reconned the last batch of SS31 w/regular & it's fine.

                                        N Offline
                                        N Offline
                                        Nuncles
                                        wrote last edited by Nuncles
                                        #39

                                        @Eleanor My first vial of SS-31 was with sodium chloride, but on reconning my second I grabbed (by habit) my bac water. So I decided to try it and see how different it would be. Like you said, it really wasn't that different. I would say the irritation was noticeable for about 30 minutes with sodium chloride and about an hour for bac. I will admit though that reconned with twice as much bac as sodium chloride.

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                                        • N Nuncles

                                          @Eleanor My first vial of SS-31 was with sodium chloride, but on reconning my second I grabbed (by habit) my bac water. So I decided to try it and see how different it would be. Like you said, it really wasn't that different. I would say the irritation was noticeable for about 30 minutes with sodium chloride and about an hour for bac. I will admit though that reconned with twice as much bac as sodium chloride.

                                          E Offline
                                          E Offline
                                          Eleanor
                                          wrote last edited by
                                          #40

                                          @Nuncles I had a similar experience but have not noticed any sort of difference at all.

                                          @jtcjeff NAD+ buf doesn't bother me regardless of the BAC I use, I use a lot of it. Problem solved.

                                          Proud to be on a gubmint watch list

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