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Vial rubber tops too hard to pierce

Scheduled Pinned Locked Moved Peptide Discussion
researchingreconstitution
32 Posts 10 Posters 2.6k Views 1 Watching
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  • hunt_akH hunt_ak

    @Stan-Douglas for those wanting to see what Stan is probably printing on his machine 🙂

    Most popular:
    https://makerworld.com/en/models/1763906-syringe-needle-vial-guide?from=search#profileId-1876831

    Couple other options:
    https://makerworld.com/en/models/2616160-peptide-insulin-syringe-guide-for-3ml-vial?from=search#profileId-2887042

    https://makerworld.com/en/models/2444714-steadydraw-syringe-and-vial-injection-support?from=search#profileId-2683098

    pep_researcherP Offline
    pep_researcherP Offline
    pep_researcher
    wrote last edited by pep_researcher
    #19

    @hunt_ak lol that's excessive engineering just to keep using a poorly made rubber stopper. 😂

    Why not just transfer pep to a better sterile empty vial with good quality rubber top? I posted it here that those have smooth buttery rubber stoppers, no piercing struggles.

    But I wanted to hear from the community if they are experiencing this, and looks like they are. I'm not alone.

    1 Reply Last reply
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    • pep_researcherP pep_researcher

      @EXTROPIAN or just get yourself better vials and transfer the liquid to it and avoid the headache of piercing poorly made rubber stoppers from China!

      Extra ALK or similar good quality sterile vials are not that big an expense.

      We can't have it all ways unfortunately.

      EXTROPIANE Offline
      EXTROPIANE Offline
      EXTROPIAN
      wrote last edited by EXTROPIAN
      #20

      @pep_researcher If you're going through all that trouble the just do pens/cartridges. Im sure you can still stick a 23-25G in those vials to transfer. If it is a quality issue then there is a chance on leaching, degradation of who knows what these new butyl rubber stoppers quality is today. "Rising costs for butyl and halobutyl rubber increased in early 2026 driven by higher expenses for isobutylene and strong demand from industrial and tire manufacturing sectors."

      2M

      pep_researcherP 1 Reply Last reply
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      • EXTROPIANE EXTROPIAN

        @pep_researcher If you're going through all that trouble the just do pens/cartridges. Im sure you can still stick a 23-25G in those vials to transfer. If it is a quality issue then there is a chance on leaching, degradation of who knows what these new butyl rubber stoppers quality is today. "Rising costs for butyl and halobutyl rubber increased in early 2026 driven by higher expenses for isobutylene and strong demand from industrial and tire manufacturing sectors."

        pep_researcherP Offline
        pep_researcherP Offline
        pep_researcher
        wrote last edited by
        #21

        @EXTROPIAN I'm sitting on a huge stockpile of ordinary noodles and vials so I'm unwilling to switch right now. Will consider in the future.

        But I agree it's a legit good option especially for precise dose measurement.

        EXTROPIANE 1 Reply Last reply
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        • pep_researcherP pep_researcher

          FWIW I had got some 2ml ALK vials. I transferred my reconned pep to it. ALK rubber stoppers are smooth like butter.

          So it's not about individual skill to pierce the vial. It ain't rocket science and I ain't RUO newb. Been researching for several months now and this problem didn't exist 6 months ago.

          E Offline
          E Offline
          Eleanor
          wrote last edited by
          #22

          @pep_researcher said:

          FWIW I had got some 2ml ALK vials. I transferred my reconned pep to it. ALK rubber stoppers are smooth like butter.

          So it's not about individual skill to pierce the vial. It ain't rocket science and I ain't RUO newb. Been researching for several months now and this problem didn't exist 6 months ago.

          The larger ALK vials are not smooth. They can be tough as a leather boot. I have lots of them and struggle getting the 23 through the stopper.

          Proud to be on a gubmint watch list

          pep_researcherP 1 Reply Last reply
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          • pep_researcherP pep_researcher

            @EXTROPIAN I'm sitting on a huge stockpile of ordinary noodles and vials so I'm unwilling to switch right now. Will consider in the future.

            But I agree it's a legit good option especially for precise dose measurement.

            EXTROPIANE Offline
            EXTROPIANE Offline
            EXTROPIAN
            wrote last edited by EXTROPIAN
            #23

            @pep_researcher Or you can sacrifice one needle to punch a few holes in the rubber stopper Target area / Puncture site to soften it up.

            2M

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            • E Eleanor

              @pep_researcher said:

              FWIW I had got some 2ml ALK vials. I transferred my reconned pep to it. ALK rubber stoppers are smooth like butter.

              So it's not about individual skill to pierce the vial. It ain't rocket science and I ain't RUO newb. Been researching for several months now and this problem didn't exist 6 months ago.

              The larger ALK vials are not smooth. They can be tough as a leather boot. I have lots of them and struggle getting the 23 through the stopper.

              pep_researcherP Offline
              pep_researcherP Offline
              pep_researcher
              wrote last edited by pep_researcher
              #24

              @Eleanor how much larger? Like 20ml or 5ml?

              I actually have Ultra Spec not ALK. Have used 5ml and no issues with rubber stopper. Smooth like butter.

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              • E Offline
                E Offline
                Eleanor
                wrote last edited by
                #25

                I have both types of vials and I don't have a problem with smaller needles for injection, only the mixing needles seem difficult.

                Proud to be on a gubmint watch list

                pep_researcherP 1 Reply Last reply
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                • E Eleanor

                  I have both types of vials and I don't have a problem with smaller needles for injection, only the mixing needles seem difficult.

                  pep_researcherP Offline
                  pep_researcherP Offline
                  pep_researcher
                  wrote last edited by
                  #26

                  @Eleanor I'm confused so do you have a problem with the ALK vial rubber tops or not?

                  If you do I was asking is it for specific vial size? 2ml, 5ml, 10ml, 20ml?

                  1 Reply Last reply
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                  • E Eleanor

                    @Americanchild Got a link to that guide?

                    AmericanchildA Offline
                    AmericanchildA Offline
                    Americanchild
                    wrote last edited by
                    #27

                    @Eleanor https://www.etsy.com/listing/1795081847/syringe-guide-reusable-peptide-vial

                    E 1 Reply Last reply
                    1
                    • AmericanchildA Americanchild

                      @Eleanor https://www.etsy.com/listing/1795081847/syringe-guide-reusable-peptide-vial

                      E Offline
                      E Offline
                      Eleanor
                      wrote last edited by
                      #28

                      @Americanchild Thanks much! Hoping to find something for 3, 5 & 10ml too. Don't know if they make them, yet.

                      Proud to be on a gubmint watch list

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                      • AmericanchildA Offline
                        AmericanchildA Offline
                        Americanchild
                        wrote last edited by
                        #29

                        I would email the seller because he prints these himself.I would think that he would be able to come up with guides for the larger vials. I have a slight tremor from a medication that I take for neuropathy, and these guides have been a lifesaver.

                        E 1 Reply Last reply
                        1
                        • AmericanchildA Americanchild

                          I would email the seller because he prints these himself.I would think that he would be able to come up with guides for the larger vials. I have a slight tremor from a medication that I take for neuropathy, and these guides have been a lifesaver.

                          E Offline
                          E Offline
                          Eleanor
                          wrote last edited by
                          #30

                          @Americanchild It's not the caps in my case, it's the size of the needle. My 29G 5/16 goes through all of them like butter, no matter where they land, but the 23G 1.5" is a different matter. This is NOT your case, I get that, just me.

                          Proud to be on a gubmint watch list

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                          • AmericanchildA Offline
                            AmericanchildA Offline
                            Americanchild
                            wrote last edited by
                            #31

                            Sorry I don't have a solution for that, but I understand the frustration.

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                            • EXTROPIANE Offline
                              EXTROPIANE Offline
                              EXTROPIAN
                              wrote last edited by
                              #32

                              PRD2016InjectionPort401.png

                              Or you can use an injection-port with a Luer lock needle. You might be able to pull with a insulin needle.

                              2M

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