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Dihexa Research Protocols and Efficacy

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  • EXTROPIANE EXTROPIAN

    It there anyone who has done semax, selnak, adamax, celebrolyson and dihexa? I interested in the comparisons? I am interested on the onset comparisons.

    ResearchCatR Offline
    ResearchCatR Offline
    ResearchCat
    wrote last edited by
    #15

    @EXTROPIAN I have researched Semax, Selank, and Dihexa. I think dihexa is tough to qualify (qualitate?), describe because it takes effect over time. Semax definitely makes me more alert, but also prone to annoyance. I only recently started playing with semax - i bought a vial from a friend - and now I need to buy a kit.

    I think semax is interesting because I have noticed I am more willing to engage socially and conversations and meetings flow better. This is very interesting to me as I generally loathe work meetings and large social gatherings and semax could be useful for this without, you know, being meth.

    I do think that the dihexa has made me sharper mentally, but it is hard to provide specifics beyond a general statement like, ‘I feel like mentally difficult tasks are easier and my mind is clearer.’ I still need to spend much less time on garbage activities.

    Yeah, well, I’m just here for the research, man. - The Dude

    If I haven’t liked your post, no offense. I have exceeded my daily allowance.

    1 Reply Last reply
    1
    • EXTROPIANE EXTROPIAN

      @kenhnsy Dihexa and DMSO. How did you mix it?

      kenhnsyK Offline
      kenhnsyK Offline
      kenhnsy
      wrote last edited by
      #16

      @EXTROPIAN said:

      @kenhnsy Dihexa and DMSO. How did you mix it?

      I put DMSO into a 3ml vial of 1g of Dihexa, hoping I could dispense it via a syringe and blunt needle.

      Not so. It makes a viscous paste. So I used a micro scoop to meter it out for sublingual use. This definitely worked. But I can't be sure it was better than just cutting it with theanine powder, grinding it all in a mortar and pestle, then making pills.
      I was going by someone's claim that the DMSO makes Dihexa more absorbant. I have no comparision to make even a poor data point. But this is an easy method. Just weigh everything and find a scoop volume that works out to your dose.

      EXTROPIANE 1 Reply Last reply
      1
      • ResearchCatR Offline
        ResearchCatR Offline
        ResearchCat
        wrote last edited by ResearchCat
        #17

        Most of my knowledge of DMSO goes back to when I was a kid and people were using it for all sorts of things to rub on their skin for pain relief or performance enhancement. And then it disappeared as many sources for it disappeared. My understanding is that DMSO has exceedingly high absorption/penetration so whatever is in it or on your skin when you wipe it on is getting absorbed into your system.

        I hadn’t heard of injecting dihexa, and I know it’s a bit challenging to make capsules consistently, or at least it is in this space. I suppose you could try dissolving it in DMSO and rub it on your skin, if you could measure consistently.

        Edit: I guess pure DMSO is pretty cheap and available on Amazon if one was interested in experimentation. I think I just came up with a peptide cream business plan. 🤣

        Yeah, well, I’m just here for the research, man. - The Dude

        If I haven’t liked your post, no offense. I have exceeded my daily allowance.

        kenhnsyK 1 Reply Last reply
        0
        • ResearchCatR ResearchCat

          Most of my knowledge of DMSO goes back to when I was a kid and people were using it for all sorts of things to rub on their skin for pain relief or performance enhancement. And then it disappeared as many sources for it disappeared. My understanding is that DMSO has exceedingly high absorption/penetration so whatever is in it or on your skin when you wipe it on is getting absorbed into your system.

          I hadn’t heard of injecting dihexa, and I know it’s a bit challenging to make capsules consistently, or at least it is in this space. I suppose you could try dissolving it in DMSO and rub it on your skin, if you could measure consistently.

          Edit: I guess pure DMSO is pretty cheap and available on Amazon if one was interested in experimentation. I think I just came up with a peptide cream business plan. 🤣

          kenhnsyK Offline
          kenhnsyK Offline
          kenhnsy
          wrote last edited by
          #18

          @ResearchCat said:

          I suppose you could try dissolving it in DMSO and rub it on your skin

          I have been wanting to try this. This guy https://www.youtube.com/@ultimateformulations told me that an easy transdermal delivery vehicle is 40% DMSO and 60% glycerin. Watch out for the fact that 25% of people will smell DMSO as the worst body odor known to man. I found out the hard way.
          Putting a dab onto a piece of paper medical tape would be pretty easy. However, given my notoriety as a peptide freak, I am hesitant to start walking around with pieces of tape attached randomly to my body parts.

          ResearchCatR 1 Reply Last reply
          2
          • kenhnsyK kenhnsy

            @EXTROPIAN said:

            @kenhnsy Dihexa and DMSO. How did you mix it?

            I put DMSO into a 3ml vial of 1g of Dihexa, hoping I could dispense it via a syringe and blunt needle.

            Not so. It makes a viscous paste. So I used a micro scoop to meter it out for sublingual use. This definitely worked. But I can't be sure it was better than just cutting it with theanine powder, grinding it all in a mortar and pestle, then making pills.
            I was going by someone's claim that the DMSO makes Dihexa more absorbant. I have no comparision to make even a poor data point. But this is an easy method. Just weigh everything and find a scoop volume that works out to your dose.

            EXTROPIANE Offline
            EXTROPIANE Offline
            EXTROPIAN
            wrote last edited by EXTROPIAN
            #19

            @kenhnsy So you reconstituted 3ml of dmso in a 3ml bottle with 1g of dihexa to inject? My brother just stop there. DMSO is nothing to mess around with. I have a bottle of DMSO trying to figure out how to safely apply it. I just want to know how much you sublingual. Guess it worked.

            Later I will test peptides transdermal or topical drug delivery and DMSO will be in the mix.

            L-theamine and coffee the best!

            2M

            kenhnsyK 2 Replies Last reply
            0
            • kenhnsyK kenhnsy

              @ResearchCat said:

              I suppose you could try dissolving it in DMSO and rub it on your skin

              I have been wanting to try this. This guy https://www.youtube.com/@ultimateformulations told me that an easy transdermal delivery vehicle is 40% DMSO and 60% glycerin. Watch out for the fact that 25% of people will smell DMSO as the worst body odor known to man. I found out the hard way.
              Putting a dab onto a piece of paper medical tape would be pretty easy. However, given my notoriety as a peptide freak, I am hesitant to start walking around with pieces of tape attached randomly to my body parts.

              ResearchCatR Offline
              ResearchCatR Offline
              ResearchCat
              wrote last edited by
              #20

              @kenhnsy said:

              @ResearchCat said:

              I suppose you could try dissolving it in DMSO and rub it on your skin

              Watch out for the fact that 25% of people will smell DMSO as the worst body odor known to man.

              Apparently, many of my coworkers are using DMSO and I only just now realized it. 🤣

              Yeah, well, I’m just here for the research, man. - The Dude

              If I haven’t liked your post, no offense. I have exceeded my daily allowance.

              EXTROPIANE 1 Reply Last reply
              0
              • EXTROPIANE EXTROPIAN

                @kenhnsy So you reconstituted 3ml of dmso in a 3ml bottle with 1g of dihexa to inject? My brother just stop there. DMSO is nothing to mess around with. I have a bottle of DMSO trying to figure out how to safely apply it. I just want to know how much you sublingual. Guess it worked.

                Later I will test peptides transdermal or topical drug delivery and DMSO will be in the mix.

                L-theamine and coffee the best!

                kenhnsyK Offline
                kenhnsyK Offline
                kenhnsy
                wrote last edited by
                #21

                @EXTROPIAN said:

                @kenhnsy So you reconstituted 3ml of dmso in a 3ml bottle with 1g of dihexa to inject?

                NOT TO INJECT.
                The ratio was something close to that. It did not make a solution and my DMSO was not RUO quality. Given the efficacy of sublingual use, I doubt it is worth going to the trouble of injecting. I could not find the solubility info for this mix and it is too expensive to play with.
                I would have rather used a liquid dispensed through a syringe to meter for sublingual use. But DMSO is a weird substance that likes to freeze depending on what type of container it is in. So be sure you weigh everything as you go so you can know how much is in a given volume (scoop).

                1 Reply Last reply
                1
                • T TBone

                  @kenhnsy that’s great to hear. I hope I feel the same. I’m interested in the Adamax as well and have thought about ordering some.

                  I have some Cerebrolysin in the 2ml ampules. I’ve been nervous to try them as it’s my understanding the minimum dose is 2-5 ml intramuscularly which is above anything I’ve researched with to date.

                  kenhnsyK Offline
                  kenhnsyK Offline
                  kenhnsy
                  wrote last edited by
                  #22

                  @TBone An excellent tutorial and a shame we are losing this vendor https://www.youtube.com/watch?v=zeg1zC-E8Xc .

                  1 Reply Last reply
                  1
                  • EXTROPIANE EXTROPIAN

                    @kenhnsy So you reconstituted 3ml of dmso in a 3ml bottle with 1g of dihexa to inject? My brother just stop there. DMSO is nothing to mess around with. I have a bottle of DMSO trying to figure out how to safely apply it. I just want to know how much you sublingual. Guess it worked.

                    Later I will test peptides transdermal or topical drug delivery and DMSO will be in the mix.

                    L-theamine and coffee the best!

                    kenhnsyK Offline
                    kenhnsyK Offline
                    kenhnsy
                    wrote last edited by
                    #23

                    @EXTROPIAN said:

                    how much you sublingual

                    15 mg daily was plenty of an effect for me.
                    I have never had a problem handling DMSO nor taking a tablespoon orally. I think there is an urban fear that one will immediately dissolve into a puddle of amino acids if you touch it.

                    EXTROPIANE 1 Reply Last reply
                    0
                    • ResearchCatR ResearchCat

                      @kenhnsy said:

                      @ResearchCat said:

                      I suppose you could try dissolving it in DMSO and rub it on your skin

                      Watch out for the fact that 25% of people will smell DMSO as the worst body odor known to man.

                      Apparently, many of my coworkers are using DMSO and I only just now realized it. 🤣

                      EXTROPIANE Offline
                      EXTROPIANE Offline
                      EXTROPIAN
                      wrote last edited by
                      #24

                      @ResearchCat I am going to open and take a wiff for science. Mine is still sealed.

                      2M

                      1 Reply Last reply
                      1
                      • kenhnsyK kenhnsy

                        @EXTROPIAN said:

                        how much you sublingual

                        15 mg daily was plenty of an effect for me.
                        I have never had a problem handling DMSO nor taking a tablespoon orally. I think there is an urban fear that one will immediately dissolve into a puddle of amino acids if you touch it.

                        EXTROPIANE Offline
                        EXTROPIANE Offline
                        EXTROPIAN
                        wrote last edited by EXTROPIAN
                        #25

                        @kenhnsy yes I read the warnings but I also read being applied with caution but not strictly. "desolved in amino acids" too funny.

                        2M

                        1 Reply Last reply
                        0
                        • EXTROPIANE Offline
                          EXTROPIANE Offline
                          EXTROPIAN
                          wrote last edited by
                          #26

                          giphy.gif

                          2M

                          1 Reply Last reply
                          1
                          • Mydogdaryl423M Mydogdaryl423

                            @researchcat I had a similiar experience to yours with Semax. I did not like the effects of it at all. It made me highly irritable.

                            CMEffie17C Offline
                            CMEffie17C Offline
                            CMEffie17
                            wrote last edited by
                            #27

                            @Mydogdaryl423 said:

                            @researchcat I had a similiar experience to yours with Semax. I did not like the effects of it at all. It made me highly irritable.

                            I have only tried Adamax (but would love to try Dihexa at some point). I didn’t put two and two together right away but the Adamax made me not only a bit irritable most of the time, but also much more prone to angry outbursts. 😕 Had to stop.

                            Retired chemist & pharmacy tech.
                            Seeking lower $/mg, with robust COA’s

                            EXTROPIANE 1 Reply Last reply
                            1
                            • CMEffie17C CMEffie17

                              @Mydogdaryl423 said:

                              @researchcat I had a similiar experience to yours with Semax. I did not like the effects of it at all. It made me highly irritable.

                              I have only tried Adamax (but would love to try Dihexa at some point). I didn’t put two and two together right away but the Adamax made me not only a bit irritable most of the time, but also much more prone to angry outbursts. 😕 Had to stop.

                              EXTROPIANE Offline
                              EXTROPIANE Offline
                              EXTROPIAN
                              wrote last edited by EXTROPIAN
                              #28

                              @CMEffie17 I have Semax, Selank, Adamax, Celebrolysin, NAD+, GHKcu, Retatrutide in 5-10ml nasal sprayers. Yes I am researching all intranasal, focusing on the brain. As for Adamax, I have 10mg in 8ml and it is nothing to sit around considering the half life. Perfect for an active life. Semax you have a little more control due to the shorter half life, it kick in right away. Selank for stress, anxiety, cognitive fatigue. Too much will put you sleep. You have to find their sweet spot. If you feel they are too much dilute and titrate up for better control. That goes with all nootropics and peptide that have a quick onset. Learn how to microdose and titrate up. I use to bite off pills till I felt it right. Be patient.

                              I been researching oral phamalogical and natural nootropics for years. Peptides are at a whole different level. This round of peptide I will be ordering Dihexa, Pinealon to research and looking for a good deal on NA-Selank. I will also restock on the following:
                              CDP- Choline
                              Modafinil
                              Bromantane
                              9-MeBc
                              Alpha gpc
                              Noopept
                              Adamax
                              Semax and Selank.
                              *Hint hint... looking for deals

                              2M

                              CMEffie17C 1 Reply Last reply
                              4
                              • EXTROPIANE EXTROPIAN

                                @CMEffie17 I have Semax, Selank, Adamax, Celebrolysin, NAD+, GHKcu, Retatrutide in 5-10ml nasal sprayers. Yes I am researching all intranasal, focusing on the brain. As for Adamax, I have 10mg in 8ml and it is nothing to sit around considering the half life. Perfect for an active life. Semax you have a little more control due to the shorter half life, it kick in right away. Selank for stress, anxiety, cognitive fatigue. Too much will put you sleep. You have to find their sweet spot. If you feel they are too much dilute and titrate up for better control. That goes with all nootropics and peptide that have a quick onset. Learn how to microdose and titrate up. I use to bite off pills till I felt it right. Be patient.

                                I been researching oral phamalogical and natural nootropics for years. Peptides are at a whole different level. This round of peptide I will be ordering Dihexa, Pinealon to research and looking for a good deal on NA-Selank. I will also restock on the following:
                                CDP- Choline
                                Modafinil
                                Bromantane
                                9-MeBc
                                Alpha gpc
                                Noopept
                                Adamax
                                Semax and Selank.
                                *Hint hint... looking for deals

                                CMEffie17C Offline
                                CMEffie17C Offline
                                CMEffie17
                                wrote last edited by
                                #29

                                @EXTROPIAN said:

                                @CMEffie17 I have Semax, Selank, Adamax, Celebrolysin, NAD+, GHKcu, Retatrutide in 5-10ml nasal sprayers. Yes I am researching all intranasal, focusing on the brain. As for Adamax, I have 10mg in 8ml and it is nothing to sit around considering the half life. Perfect for an active life. Semax you have a little more control due to the shorter half life, it kick in right away. Selank for stress, anxiety, cognitive fatigue. Too much will put you sleep. You have to find their sweet spot. If you feel they are too much dilute and titrate up for better control. That goes with all nootropics and peptide that have a quick onset. Learn how to microdose and titrate up. I use to bite off pills till I felt it right. Be patient.

                                These are excellent points! Maybe I should try it again just a more dilute, or much smaller dose. Thanks for the encouragement! And good luck to you with all that you are doing which sounds (daunting!) 😳 Impressed! 👏👏

                                Retired chemist & pharmacy tech.
                                Seeking lower $/mg, with robust COA’s

                                1 Reply Last reply
                                0
                                • hunt_akH Offline
                                  hunt_akH Offline
                                  hunt_ak
                                  wrote last edited by
                                  #30

                                  I'm very interested in dihexa from a neuroprotective standpoint. Seems you can get in lyophilized powder for subq/intranasal injection or in pill form?

                                  One of my gray suppliers doesn't have it on 'her' sheet. I would view this as a long term protective play from using exogenous testosterone and overall aging.

                                  1 Reply Last reply
                                  0
                                  • hunt_akH Offline
                                    hunt_akH Offline
                                    hunt_ak
                                    wrote last edited by
                                    #31

                                    I'm also seeing NTX has the 7.5mg pills but boy it's definitely not inexpensive. I assume this is a daily oral?

                                    ResearchCatR 1 Reply Last reply
                                    1
                                    • T TBone

                                      @kenhnsy that’s great to hear. I hope I feel the same. I’m interested in the Adamax as well and have thought about ordering some.

                                      I have some Cerebrolysin in the 2ml ampules. I’ve been nervous to try them as it’s my understanding the minimum dose is 2-5 ml intramuscularly which is above anything I’ve researched with to date.

                                      O Offline
                                      O Offline
                                      ogsteve
                                      wrote last edited by
                                      #32

                                      @TBone
                                      I’m in the middle of trying this right now and I gotta tell you that this stuff injects im incredibly smoothly. It’s the weirdest thing. I did 3 mL in my butt threw a 28 gauge and it just goes in there without any discomfort.

                                      That said I’ve got the 5 mL vials and I’m disinclined to inject 5 mL at a time so I split it up into several doses about 2 to 3 mL every day.

                                      You do need to make sure that you filter out any glass though

                                      T 1 Reply Last reply
                                      0
                                      • O ogsteve

                                        @TBone
                                        I’m in the middle of trying this right now and I gotta tell you that this stuff injects im incredibly smoothly. It’s the weirdest thing. I did 3 mL in my butt threw a 28 gauge and it just goes in there without any discomfort.

                                        That said I’ve got the 5 mL vials and I’m disinclined to inject 5 mL at a time so I split it up into several doses about 2 to 3 mL every day.

                                        You do need to make sure that you filter out any glass though

                                        T Offline
                                        T Offline
                                        TBone
                                        wrote last edited by
                                        #33

                                        @ogsteve I know my issue is mental at this point. But I need to just do it. Would love to hear your feedback on results!

                                        Comfort is the worst addiction - Marcus Aurelius

                                        O 1 Reply Last reply
                                        0
                                        • T TBone

                                          @ogsteve I know my issue is mental at this point. But I need to just do it. Would love to hear your feedback on results!

                                          O Offline
                                          O Offline
                                          ogsteve
                                          wrote last edited by ogsteve
                                          #34

                                          @TBone check dm

                                          Long and short of it is that i’m hitting it with freaking everything I can as fast as I deem fruitful to try to get results. This is not “research“ this is try to fix a problem.

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