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  1. Randy the Rats Research Forum
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  3. Klotho / FLGR242 (albumin-bound new tech)
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Klotho / FLGR242 (albumin-bound new tech)

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  • RandyR Randy

    @ImaFrogNotaRat alpha biomed and paramount are the same thing. they stopped prodcuing coa's about 6 months ago. Im not sure what Trevor is up to over there anymore.

    ImaFrogNotaRatI Offline
    ImaFrogNotaRatI Offline
    ImaFrogNotaRat
    wrote last edited by
    #201

    @Randy Regarding your comment about the COAs at alpha BioMed being stopped 6 months ago, I have a theory.

    I noticed that Trevor and JC are good friends, and that though they (ABM) and Biolongevity Labs are two separate companies, that collaborative relationship is why they both have alpha-KlothoLR (alpha-Klotho MAB on COAs), and FLGR-242. I wonder if Alpha BioMed produces product for Biolongevity. That might explain why COAs for the former are not being published for fear of someone making that connection?

    D 1 Reply Last reply
    0
    • ImaFrogNotaRatI ImaFrogNotaRat

      @Randy Regarding your comment about the COAs at alpha BioMed being stopped 6 months ago, I have a theory.

      I noticed that Trevor and JC are good friends, and that though they (ABM) and Biolongevity Labs are two separate companies, that collaborative relationship is why they both have alpha-KlothoLR (alpha-Klotho MAB on COAs), and FLGR-242. I wonder if Alpha BioMed produces product for Biolongevity. That might explain why COAs for the former are not being published for fear of someone making that connection?

      D Offline
      D Offline
      diegoc
      wrote last edited by
      #202

      @ImaFrogNotaRat is it cheaper on Trevors site?

      I saw a video were Alex was talking about KLOTHO and he was testing another vendor

      ImaFrogNotaRatI 1 Reply Last reply
      0
      • D diegoc

        @ImaFrogNotaRat is it cheaper on Trevors site?

        I saw a video were Alex was talking about KLOTHO and he was testing another vendor

        ImaFrogNotaRatI Offline
        ImaFrogNotaRatI Offline
        ImaFrogNotaRat
        wrote last edited by
        #203

        @diegoc Yes, at Biolongevity Labs it's Christmas in July - 50% Off Sitewide. So their FLGR-242 and alpha-Klotho LR are each $249.50 per pair of vials. That's not including the jayc discount code.

        I'm on both of those.

        1 Reply Last reply
        1
        • P Offline
          P Offline
          PeptidePete
          wrote last edited by
          #204

          Ok, buckle up, caffeinate, bookmark.

          I said I was dropping to 2.5mg weekly FLGR. I lied. I changed my mind for the sake of personal research and due to new info coming in over the transom. For a period of time (x months) I am doing one vial FLGR 3x per week. So 15mg+/- per week. Xmas in July gave me 48 more vials to add to my existing stash of 46 vials.

          I've previously mentioned Liz Parrish, linked below is her latest video. Readers of this thread are going to find it thought-provoking on multiple levels. Oh yeah...She invented Follistatin and Klotho gene therapy. I now deeply regret having done an injection of FOX04-DRI. Senescent cells are turning out to NOT be what they are sold as- dead waste. Does Follistatin have a max dose? Watch the video and get ready for shock.

          Relevant side notes- it is my understanding the gene therapy (either of the two kinds) has not been as efficacious and durable as originally thought. BioLongevity Labs FLGR/Klotho FTW. Also- after watching the expose video on Adeel Khan I would NEVER do any injected gene therapy.

          Shifting gears: Lesson learned the hard way- CHECK YOUR FERRITIN. Some "influencers" yapping YOU GOTTA GIVE BLOOD all the time. Wrong mofo, you need to get labs done and quantify where you are. Operating under information previously thought correct, I did therapeutic phlebotomies every two months for several years when I was incorrectly using injected testosterone. Terrible mistake, I tanked my ferritin to 15-20 ng/ml and the downstream effects of that are manifold. Including fcking up your thyroid function. NOT GOOD.

          Doesn't matter WHAT your hematocrit is (specifically) that results from testosterone use, you should NEVER get bled. Pull that string...spoiler alert- tell me why blood doping athletes don't drop dead all the time. Fucking stupid ass mainstream "doctors" will fucking kill you with their ignorance.

          So I am on a strict daily diet of baked (kills the pathogens) oysters + octopus legs + scrambled eggs for the next month or two to rebuild my levels. No, NOT beef (not as much heme iron!) and sure as fck not spinach (iron bound by nasty oxalates). Not liver because I don't want Vit A overdose (it's a thing). Do your research. Use lemon juice on the seafood to loosen the iron binding and enhance bioavailability. After a week, I already feel much better.

          I think DIEGOC and I are brothers with different mothers. Anyone having a question for me, see if he has already spoke of it, because most likely I have the same view he does.

          Another gear shift: A few weeks ago I initiated research of adding Test Cyp, EOD, to my OralOnly.com sublingual T in an effort to restart my Estradiol aromatization which I unintentionally took to zero due to an excess of an "oil" I've been researching. Lesson learned, that's research. I'll be tracking my labs to see if adding the EOD Cyp alters the otherwise perfect SHBG/Hematocrit/Hemoglobin/Prolactin/DHT on the sublingual only.

          All this stuff is fully interconnected with FLGR/Klotho. It ALL works together as gears in a gearbox. One broken gear tooth or gear, and you'll be going nowhere fast.

          Shift to overdrive- I have now researched Cell Factors MAX twice, I swear I feel a difference, feel "better" and "clearer". Yeah mushy stuff. Do your research, there is real science behind this. I just stocked up on sale. Never reconstitute with BAC water, ONLY Sterile Water!! BAC instantly degrades it.

          Liz Parrish: https://youtu.be/Z4j5DL0-hM8?si=BMh_cejeEs9viGet

          FLGR/Klotho info from Mike: https://streamyard.com/watch/diBBqZzAJkfC

          D vpeptidesV 3 Replies Last reply
          3
          • P Offline
            P Offline
            PeptidePete
            wrote last edited by PeptidePete
            #205

            Oh yeah- regarding comments of "TOFI" Thin Outside Fat Inside issues.

            As I previously posted I follow the regimen/protocol of Dr Sean Omara.

            Beef/Seafood (Kai Gourmet=Fremantle Octopus)
            Limited dairy including homemade yogurt (grass-fed A2 milk/half and half), raw aged/blue cheese in small amounts.
            Fermented veg
            Butter
            Soy/Corn-free eggs
            Fish roe
            Organic Macadamia/Walnut butter in the yogurt (Blue Mountain Organics)
            Organic farm sourced avocados (Corkysnuts.com)

            No carbs, no fruit, no sugars of ANY kind, no flour, no veg.

            Running/cycling is counter productive. Sprinting, short uphill fast walks, variable resistance training to failure approx 3x per week 20 min per session is my regimen.

            Eating high protein while on FLGR is not an option. Jaquish Biomedical Fortagen is in my opinion the perfect protein in a sea of shit products.

            Morning sun of course 🙂 Dry sauna (not infrared)

            1 Reply Last reply
            2
            • P PeptidePete

              Ok, buckle up, caffeinate, bookmark.

              I said I was dropping to 2.5mg weekly FLGR. I lied. I changed my mind for the sake of personal research and due to new info coming in over the transom. For a period of time (x months) I am doing one vial FLGR 3x per week. So 15mg+/- per week. Xmas in July gave me 48 more vials to add to my existing stash of 46 vials.

              I've previously mentioned Liz Parrish, linked below is her latest video. Readers of this thread are going to find it thought-provoking on multiple levels. Oh yeah...She invented Follistatin and Klotho gene therapy. I now deeply regret having done an injection of FOX04-DRI. Senescent cells are turning out to NOT be what they are sold as- dead waste. Does Follistatin have a max dose? Watch the video and get ready for shock.

              Relevant side notes- it is my understanding the gene therapy (either of the two kinds) has not been as efficacious and durable as originally thought. BioLongevity Labs FLGR/Klotho FTW. Also- after watching the expose video on Adeel Khan I would NEVER do any injected gene therapy.

              Shifting gears: Lesson learned the hard way- CHECK YOUR FERRITIN. Some "influencers" yapping YOU GOTTA GIVE BLOOD all the time. Wrong mofo, you need to get labs done and quantify where you are. Operating under information previously thought correct, I did therapeutic phlebotomies every two months for several years when I was incorrectly using injected testosterone. Terrible mistake, I tanked my ferritin to 15-20 ng/ml and the downstream effects of that are manifold. Including fcking up your thyroid function. NOT GOOD.

              Doesn't matter WHAT your hematocrit is (specifically) that results from testosterone use, you should NEVER get bled. Pull that string...spoiler alert- tell me why blood doping athletes don't drop dead all the time. Fucking stupid ass mainstream "doctors" will fucking kill you with their ignorance.

              So I am on a strict daily diet of baked (kills the pathogens) oysters + octopus legs + scrambled eggs for the next month or two to rebuild my levels. No, NOT beef (not as much heme iron!) and sure as fck not spinach (iron bound by nasty oxalates). Not liver because I don't want Vit A overdose (it's a thing). Do your research. Use lemon juice on the seafood to loosen the iron binding and enhance bioavailability. After a week, I already feel much better.

              I think DIEGOC and I are brothers with different mothers. Anyone having a question for me, see if he has already spoke of it, because most likely I have the same view he does.

              Another gear shift: A few weeks ago I initiated research of adding Test Cyp, EOD, to my OralOnly.com sublingual T in an effort to restart my Estradiol aromatization which I unintentionally took to zero due to an excess of an "oil" I've been researching. Lesson learned, that's research. I'll be tracking my labs to see if adding the EOD Cyp alters the otherwise perfect SHBG/Hematocrit/Hemoglobin/Prolactin/DHT on the sublingual only.

              All this stuff is fully interconnected with FLGR/Klotho. It ALL works together as gears in a gearbox. One broken gear tooth or gear, and you'll be going nowhere fast.

              Shift to overdrive- I have now researched Cell Factors MAX twice, I swear I feel a difference, feel "better" and "clearer". Yeah mushy stuff. Do your research, there is real science behind this. I just stocked up on sale. Never reconstitute with BAC water, ONLY Sterile Water!! BAC instantly degrades it.

              Liz Parrish: https://youtu.be/Z4j5DL0-hM8?si=BMh_cejeEs9viGet

              FLGR/Klotho info from Mike: https://streamyard.com/watch/diBBqZzAJkfC

              D Offline
              D Offline
              diegoc
              wrote last edited by
              #206

              @PeptidePete great update brother….

              I also learned the hard way… Ive been doing TRT for over 20 years and doing many many Bloodwork.

              Like 6 months ago i got on Reta and got completely dehydrated….

              Thats a GLP you need to be loading electrolytes and i didnt.

              So i did some Bloodwork and my hemecratic was sky high.

              Did my a blood donation…

              I still was low on hydration and electrolytes and another sky high hemecratic reading.

              Here goes another blood draw and crashed everything, Iron, Ferritin and Thyroid….

              After lots and lots of research and being guided by a couple of ppl that really know what there doing, i started on my new Optimal Bloodwork Journey.

              First thing I learned is you need at least 24-32oz of electrolytes once you wake up.

              Second on BW day its fasted but you need to start your hydration 1 hour before the min 32-48oz of water. 1 or 2 bottles then the rest timed every 15m before the draw.

              My ferretin did reach 15 however I did add 2oz of grassfed beef liver ground beef which i add to 2oz of lean ground beef almost everyday.

              3x a week i do Oysters between 6-12 per meal with Vitamin C for more absorption.

              I had really bas digestion and gut issues so absorption was really poor so ive been testing and tweaking my diet to eventually build up to ghost wipe status. 😂

              Thank you for the video links.

              Diego

              1 Reply Last reply
              0
              • P Offline
                P Offline
                PeptidePete
                wrote last edited by
                #207

                Thanks for sharing the journey my friend!

                Bristol #4 is the desired outcome (Look it up if you don't understand) 😁

                Oysters With Vit C FTW!! You understand the intricacies brother. C or citrus juice, either is good. The C gave me very bad heartburn, the citrus not. Individual variability.

                Low hydration-high hematocrit...well I'll be darned?? (wink wink)

                D 1 Reply Last reply
                1
                • P PeptidePete

                  Thanks for sharing the journey my friend!

                  Bristol #4 is the desired outcome (Look it up if you don't understand) 😁

                  Oysters With Vit C FTW!! You understand the intricacies brother. C or citrus juice, either is good. The C gave me very bad heartburn, the citrus not. Individual variability.

                  Low hydration-high hematocrit...well I'll be darned?? (wink wink)

                  D Offline
                  D Offline
                  diegoc
                  wrote last edited by
                  #208

                  @PeptidePete citrus is a big part of my meals as well.

                  I add carrot salad with lemon juice for digestion and absorption of my beef 😜

                  1 Reply Last reply
                  1
                  • P PeptidePete

                    Ok, buckle up, caffeinate, bookmark.

                    I said I was dropping to 2.5mg weekly FLGR. I lied. I changed my mind for the sake of personal research and due to new info coming in over the transom. For a period of time (x months) I am doing one vial FLGR 3x per week. So 15mg+/- per week. Xmas in July gave me 48 more vials to add to my existing stash of 46 vials.

                    I've previously mentioned Liz Parrish, linked below is her latest video. Readers of this thread are going to find it thought-provoking on multiple levels. Oh yeah...She invented Follistatin and Klotho gene therapy. I now deeply regret having done an injection of FOX04-DRI. Senescent cells are turning out to NOT be what they are sold as- dead waste. Does Follistatin have a max dose? Watch the video and get ready for shock.

                    Relevant side notes- it is my understanding the gene therapy (either of the two kinds) has not been as efficacious and durable as originally thought. BioLongevity Labs FLGR/Klotho FTW. Also- after watching the expose video on Adeel Khan I would NEVER do any injected gene therapy.

                    Shifting gears: Lesson learned the hard way- CHECK YOUR FERRITIN. Some "influencers" yapping YOU GOTTA GIVE BLOOD all the time. Wrong mofo, you need to get labs done and quantify where you are. Operating under information previously thought correct, I did therapeutic phlebotomies every two months for several years when I was incorrectly using injected testosterone. Terrible mistake, I tanked my ferritin to 15-20 ng/ml and the downstream effects of that are manifold. Including fcking up your thyroid function. NOT GOOD.

                    Doesn't matter WHAT your hematocrit is (specifically) that results from testosterone use, you should NEVER get bled. Pull that string...spoiler alert- tell me why blood doping athletes don't drop dead all the time. Fucking stupid ass mainstream "doctors" will fucking kill you with their ignorance.

                    So I am on a strict daily diet of baked (kills the pathogens) oysters + octopus legs + scrambled eggs for the next month or two to rebuild my levels. No, NOT beef (not as much heme iron!) and sure as fck not spinach (iron bound by nasty oxalates). Not liver because I don't want Vit A overdose (it's a thing). Do your research. Use lemon juice on the seafood to loosen the iron binding and enhance bioavailability. After a week, I already feel much better.

                    I think DIEGOC and I are brothers with different mothers. Anyone having a question for me, see if he has already spoke of it, because most likely I have the same view he does.

                    Another gear shift: A few weeks ago I initiated research of adding Test Cyp, EOD, to my OralOnly.com sublingual T in an effort to restart my Estradiol aromatization which I unintentionally took to zero due to an excess of an "oil" I've been researching. Lesson learned, that's research. I'll be tracking my labs to see if adding the EOD Cyp alters the otherwise perfect SHBG/Hematocrit/Hemoglobin/Prolactin/DHT on the sublingual only.

                    All this stuff is fully interconnected with FLGR/Klotho. It ALL works together as gears in a gearbox. One broken gear tooth or gear, and you'll be going nowhere fast.

                    Shift to overdrive- I have now researched Cell Factors MAX twice, I swear I feel a difference, feel "better" and "clearer". Yeah mushy stuff. Do your research, there is real science behind this. I just stocked up on sale. Never reconstitute with BAC water, ONLY Sterile Water!! BAC instantly degrades it.

                    Liz Parrish: https://youtu.be/Z4j5DL0-hM8?si=BMh_cejeEs9viGet

                    FLGR/Klotho info from Mike: https://streamyard.com/watch/diBBqZzAJkfC

                    vpeptidesV Offline
                    vpeptidesV Offline
                    vpeptides
                    wrote last edited by
                    #209

                    @PeptidePete said:

                    I now deeply regret having done an injection of FOX04-DRI.

                    Do you think now it kills off too much of the senescent cells? You need to leave some for its purposes or simply to carry-on the genome?

                    attentiion is all you need

                    P 1 Reply Last reply
                    0
                    • D Offline
                      D Offline
                      diegoc
                      wrote last edited by
                      #210

                      Whats done is done… move on

                      P 1 Reply Last reply
                      1
                      • vpeptidesV vpeptides

                        @PeptidePete said:

                        I now deeply regret having done an injection of FOX04-DRI.

                        Do you think now it kills off too much of the senescent cells? You need to leave some for its purposes or simply to carry-on the genome?

                        P Offline
                        P Offline
                        PeptidePete
                        wrote last edited by
                        #211

                        @vpeptides said:

                        @PeptidePete said:

                        I now deeply regret having done an injection of FOX04-DRI.

                        Do you think now it kills off too much of the senescent cells? You need to leave some for its purposes or simply to carry-on the genome?

                        Watched the Liz Parrish video I linked. Also her others

                        vpeptidesV 1 Reply Last reply
                        1
                        • D diegoc

                          Whats done is done… move on

                          P Offline
                          P Offline
                          PeptidePete
                          wrote last edited by
                          #212

                          @diegoc said:

                          Whats done is done… move on

                          Absolutely

                          1 Reply Last reply
                          0
                          • P PeptidePete

                            @vpeptides said:

                            @PeptidePete said:

                            I now deeply regret having done an injection of FOX04-DRI.

                            Do you think now it kills off too much of the senescent cells? You need to leave some for its purposes or simply to carry-on the genome?

                            Watched the Liz Parrish video I linked. Also her others

                            vpeptidesV Offline
                            vpeptidesV Offline
                            vpeptides
                            wrote last edited by vpeptides
                            #213

                            @PeptidePete I did watch the video, thank you, I really liked it. That's why I asked. She didn't directly reference FOXO4-DRI, only said it is only her hypothesis, not a theory, no proof, that it's not a great idea to use senolytics because in the bone marrow you are going to wash out the senescent precursor cells to the stem cells, and it is better to have at least senescent cells there than just empty holes.
                            I don't see why necessarily a senescent precursor cell is better than no cell, it's not dividing anyway. I may guess those holes might be filled with new younger cells because there will be space there now. Maybe she is right, maybe not.
                            I bought FOXO4-DRI for research at some point. I was planning to use it in a very short course, maybe 2-3 injections over a week, follow it with plasmapheresis to wash out the dead cell material from the blood, and also (important) precede FOXO with a course of Humanin to try bringing as many as possible cells out of senescence first. Then FOXO4-DRI would only affect the cells that can't be rejuvenated.
                            But I may reconsider using FOXO4-DRI with this information in mind.
                            There is also a bone marrow peptide extract Bonomarlot (Bonocore) that is claimed to restore red bone marrow to supply stem cells, I am planning to research it too.

                            attentiion is all you need

                            P 1 Reply Last reply
                            1
                            • P PeptidePete

                              Ok, buckle up, caffeinate, bookmark.

                              I said I was dropping to 2.5mg weekly FLGR. I lied. I changed my mind for the sake of personal research and due to new info coming in over the transom. For a period of time (x months) I am doing one vial FLGR 3x per week. So 15mg+/- per week. Xmas in July gave me 48 more vials to add to my existing stash of 46 vials.

                              I've previously mentioned Liz Parrish, linked below is her latest video. Readers of this thread are going to find it thought-provoking on multiple levels. Oh yeah...She invented Follistatin and Klotho gene therapy. I now deeply regret having done an injection of FOX04-DRI. Senescent cells are turning out to NOT be what they are sold as- dead waste. Does Follistatin have a max dose? Watch the video and get ready for shock.

                              Relevant side notes- it is my understanding the gene therapy (either of the two kinds) has not been as efficacious and durable as originally thought. BioLongevity Labs FLGR/Klotho FTW. Also- after watching the expose video on Adeel Khan I would NEVER do any injected gene therapy.

                              Shifting gears: Lesson learned the hard way- CHECK YOUR FERRITIN. Some "influencers" yapping YOU GOTTA GIVE BLOOD all the time. Wrong mofo, you need to get labs done and quantify where you are. Operating under information previously thought correct, I did therapeutic phlebotomies every two months for several years when I was incorrectly using injected testosterone. Terrible mistake, I tanked my ferritin to 15-20 ng/ml and the downstream effects of that are manifold. Including fcking up your thyroid function. NOT GOOD.

                              Doesn't matter WHAT your hematocrit is (specifically) that results from testosterone use, you should NEVER get bled. Pull that string...spoiler alert- tell me why blood doping athletes don't drop dead all the time. Fucking stupid ass mainstream "doctors" will fucking kill you with their ignorance.

                              So I am on a strict daily diet of baked (kills the pathogens) oysters + octopus legs + scrambled eggs for the next month or two to rebuild my levels. No, NOT beef (not as much heme iron!) and sure as fck not spinach (iron bound by nasty oxalates). Not liver because I don't want Vit A overdose (it's a thing). Do your research. Use lemon juice on the seafood to loosen the iron binding and enhance bioavailability. After a week, I already feel much better.

                              I think DIEGOC and I are brothers with different mothers. Anyone having a question for me, see if he has already spoke of it, because most likely I have the same view he does.

                              Another gear shift: A few weeks ago I initiated research of adding Test Cyp, EOD, to my OralOnly.com sublingual T in an effort to restart my Estradiol aromatization which I unintentionally took to zero due to an excess of an "oil" I've been researching. Lesson learned, that's research. I'll be tracking my labs to see if adding the EOD Cyp alters the otherwise perfect SHBG/Hematocrit/Hemoglobin/Prolactin/DHT on the sublingual only.

                              All this stuff is fully interconnected with FLGR/Klotho. It ALL works together as gears in a gearbox. One broken gear tooth or gear, and you'll be going nowhere fast.

                              Shift to overdrive- I have now researched Cell Factors MAX twice, I swear I feel a difference, feel "better" and "clearer". Yeah mushy stuff. Do your research, there is real science behind this. I just stocked up on sale. Never reconstitute with BAC water, ONLY Sterile Water!! BAC instantly degrades it.

                              Liz Parrish: https://youtu.be/Z4j5DL0-hM8?si=BMh_cejeEs9viGet

                              FLGR/Klotho info from Mike: https://streamyard.com/watch/diBBqZzAJkfC

                              vpeptidesV Offline
                              vpeptidesV Offline
                              vpeptides
                              wrote last edited by
                              #214

                              @PeptidePete said:

                              FLGR/Klotho info from Mike: https://streamyard.com/watch/diBBqZzAJkfC

                              This is mostly about their Lepto3GR product. Do you by chance have more videos about FLGR/Klotho ?

                              attentiion is all you need

                              1 Reply Last reply
                              0
                              • vpeptidesV Offline
                                vpeptidesV Offline
                                vpeptides
                                wrote last edited by
                                #215

                                For anybody interested in FLGR242, currently SlimAssist (FLGR242 2MG / 500mcg B Complex) vial is on sale for $62.50 AND Buy 3 Get 2 FREE deal. So, if you get 3 vials and get 2 free ones, you get 10MG of FLGR242 for $187.50 minus 15% JayC discount. It is even cheaper than $249.50 for 10mg sale.

                                attentiion is all you need

                                D 1 Reply Last reply
                                2
                                • S stevencarter

                                  I was in the Jay Campbell community for a month before I got pissed off and left. Almost the whole community got mad at me for talking about how tesamorelin doesnt need to be in the fridge after reconstitution. Couple of them basically called me a liar and started raving about all the results they had on tesa purchased through biolongevity labs. They all put it in the fridge after mixing and none of them ever had it gel on them or get cloudy. I made the comment that it doesnt sound like they were getting actual tesamorelin and then I posted the reconstitution instructions from the Egrifta website. The site speaks to how they had to alter the original tesamorelin due to cold gelling. Anyways im not welcome in that community anymore. Kind of let me know the level of integrity over there. Plus that dude charges insane money for bioregulators in injection form. I wont purchase anything from Jay Campbell. I dont mean to offend anyone, but to have all them people argue with me against the storage protocol on something that is widely proven and discussed made me think they were all brainwashed. You know who else is brainwashed?! Zombies, so there ya go. My chupacabra said he would make a pair of boots out of me if he caught me buying peptides for him from BLL.

                                  W Offline
                                  W Offline
                                  WowwyZowwy
                                  wrote last edited by
                                  #216

                                  @stevencarter
                                  Josh Holyfield's take...
                                  https://youtube.com/shorts/W7_ajSR8-S8?si=b4nv03GgjMgZTEW1

                                  P S 2 Replies Last reply
                                  0
                                  • W WowwyZowwy

                                    @stevencarter
                                    Josh Holyfield's take...
                                    https://youtube.com/shorts/W7_ajSR8-S8?si=b4nv03GgjMgZTEW1

                                    P Offline
                                    P Offline
                                    PeptidePete
                                    wrote last edited by PeptidePete
                                    #217

                                    @WowwyZowwy said:

                                    @stevencarter
                                    Josh Holyfield's take...
                                    https://youtube.com/shorts/W7_ajSR8-S8?si=b4nv03GgjMgZTEW1

                                    Dude...🤡

                                    This clown (Holyfield) has no clue what he is talking about, as already noted multiple times downthread.

                                    If you don't understand my comment, then you are not understanding Follistatin (details downthread). AI generated slop does not equal wisdom.

                                    1 Reply Last reply
                                    0
                                    • vpeptidesV vpeptides

                                      @PeptidePete I did watch the video, thank you, I really liked it. That's why I asked. She didn't directly reference FOXO4-DRI, only said it is only her hypothesis, not a theory, no proof, that it's not a great idea to use senolytics because in the bone marrow you are going to wash out the senescent precursor cells to the stem cells, and it is better to have at least senescent cells there than just empty holes.
                                      I don't see why necessarily a senescent precursor cell is better than no cell, it's not dividing anyway. I may guess those holes might be filled with new younger cells because there will be space there now. Maybe she is right, maybe not.
                                      I bought FOXO4-DRI for research at some point. I was planning to use it in a very short course, maybe 2-3 injections over a week, follow it with plasmapheresis to wash out the dead cell material from the blood, and also (important) precede FOXO with a course of Humanin to try bringing as many as possible cells out of senescence first. Then FOXO4-DRI would only affect the cells that can't be rejuvenated.
                                      But I may reconsider using FOXO4-DRI with this information in mind.
                                      There is also a bone marrow peptide extract Bonomarlot (Bonocore) that is claimed to restore red bone marrow to supply stem cells, I am planning to research it too.

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                                      PeptidePete
                                      wrote last edited by PeptidePete
                                      #218

                                      @vpeptides said:

                                      @PeptidePete I did watch the video, thank you, I really liked it. That's why I asked. She didn't directly reference FOXO4-DRI, only said it is only her hypothesis, not a theory, no proof, that it's not a great idea to use senolytics because in the bone marrow you are going to wash out the senescent precursor cells to the stem cells, and it is better to have at least senescent cells there than just empty holes.
                                      There is also a bone marrow peptide extract Bonomarlot (Bonocore) that is claimed to restore red bone marrow to supply stem cells, I am planning to research it too.

                                      The point is that once you lose/kill/remove the few stem cells you have remaining, THAT'S IT. They NEVER grow back or can be replaced. That is the current understanding. I'm 65, I only have a few left unless I already burned them with my FOX04 course.

                                      Humanin...I researched this heavily before dosing, I was very interested, and chose NOT to use it even once. I'd urge you to look very carefully before using it.

                                      Spoiler- research the different versions of humanin, I would not touch it.

                                      No humanin, sure as hell no FOX04. Far too many unknowns, said as a peptide fan who ran GHK-Cu at 15-20mg per day for months.

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                                        ResearchCat
                                        wrote last edited by
                                        #219

                                        @vpeptides I would recommend more research before researching FOX-04. I was very enthusiastic about it until I dug a bit deeper and got into how they don’t entirely know if senescent cells are all bad, whether cleared stem cells would be replaced, etc. There are a few other unknowns as well. It looks promising, but there are too many unknowns even for this risk taker.

                                        I gotta do more research on Cell Factors and build a Follistatin/FLGR242 protocol for the winter.

                                        Please set a funny and sarcastic signature line. It brings me joy. Thank you for your attention in this matter.

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                                        • R ResearchCat

                                          @vpeptides I would recommend more research before researching FOX-04. I was very enthusiastic about it until I dug a bit deeper and got into how they don’t entirely know if senescent cells are all bad, whether cleared stem cells would be replaced, etc. There are a few other unknowns as well. It looks promising, but there are too many unknowns even for this risk taker.

                                          I gotta do more research on Cell Factors and build a Follistatin/FLGR242 protocol for the winter.

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                                          vpeptides
                                          wrote last edited by vpeptides
                                          #220

                                          @ResearchCat Cell Factors look very very interesting. I am planning to research α-Klotho, and a low dose of 🇨🇳R242 to see the effect on fat%, in the tests and overall. FOXO4-DRI can wait 20 years or so in my case.
                                          But I am surprised you all are skeptical on Humanin. I do need to research more.

                                          attentiion is all you need

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