5-Amino-1MQ Research
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@extropian Most people don't notice any effect until they get around 25mgs+ subq. The lower dosages are probably more of a placebo type effect. I believe Randy said he has gone up to about 50mgs but he didn't really notice any benefit after going past 25mgs, so he now does 25mgs.
@Shaqdiesel Hmmm interesting.
I added 5amino-1mq and slu-pp-332 to my reta stack. While running my mitochondria stack (motsc, nad, ss-31) which made it even better running off fatty acids for fuel via 5amino and slupp . Must have been one hell of a placebo effect because since the first time I felt the difference. I went back on it yesterday. No mitochondria stack. Took 5amino-1mg and I felt it without Slurpy (need to recon anotherone). If I can run on placebo alone it would have save me quite a bit. Maybe you need to run it synergistically with others and not alone. Maybe you need to optimize your mitochondria and insulin sensitivity to make the best of it. Can't say it enough, foundation first.2M
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@Shaqdiesel Hmmm interesting.
I added 5amino-1mq and slu-pp-332 to my reta stack. While running my mitochondria stack (motsc, nad, ss-31) which made it even better running off fatty acids for fuel via 5amino and slupp . Must have been one hell of a placebo effect because since the first time I felt the difference. I went back on it yesterday. No mitochondria stack. Took 5amino-1mg and I felt it without Slurpy (need to recon anotherone). If I can run on placebo alone it would have save me quite a bit. Maybe you need to run it synergistically with others and not alone. Maybe you need to optimize your mitochondria and insulin sensitivity to make the best of it. Can't say it enough, foundation first.@EXTROPIAN I take 50mg 5-amino-1mq as a capsule 2 times a day. If I feel anything, it's a very mild flush sometimes. Not observed anything else yet, for 1 week.
I read/heard though that subq inj may be more bioavailable and that's why people take a lot less, like 1 mg. -
@Shaqdiesel Hmmm interesting.
I added 5amino-1mq and slu-pp-332 to my reta stack. While running my mitochondria stack (motsc, nad, ss-31) which made it even better running off fatty acids for fuel via 5amino and slupp . Must have been one hell of a placebo effect because since the first time I felt the difference. I went back on it yesterday. No mitochondria stack. Took 5amino-1mg and I felt it without Slurpy (need to recon anotherone). If I can run on placebo alone it would have save me quite a bit. Maybe you need to run it synergistically with others and not alone. Maybe you need to optimize your mitochondria and insulin sensitivity to make the best of it. Can't say it enough, foundation first.@EXTROPIAN @vpeptides In the end it is all N=1 research and we are all different. That is true on all peps and dosage. Some people take .5mg Reta and never have to go higher. Some shoot up to 8mgs before they actually start seeing any effect.
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I thought about running 5-Amino-1MQ together with NAD+, but when I looked into it, I found some information that this might actually be counterproductive? What do you guys think?
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I thought about running 5-Amino-1MQ together with NAD+, but when I looked into it, I found some information that this might actually be counterproductive? What do you guys think?
@jamesboyles 5-Amino-1MQ increases cellular NAD+ levels by blocking an enzyme called NNMT, which normally breaks down the building blocks needed to make NAD+. If you still want to add NAD+ I would personally do low dosages just in case. I would rather run 5amino' with MOTS. The trick here is to run the mitochondria on mostly fatty acids instead of glucose. Scroll up and see what else it does w fats.
"How It Works with NAD.
- Blocks NNMT: It stops nicotinamide N-methyltransferase (NNMT), an enzyme that tags NAD+ building blocks for disposal.
- Saves Precursors: By stopping that enzyme, it keeps nicotinamide available to build more NAD+.
- Raises Energy: Preclinical studies show this boosts cellular NAD+ levels by roughly 1.2 to 1.6-fold, helping cells create energy more efficiently."
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Update- I moved to 25mg subq as @randy did, noticed no difference. However some weeks ago I added oral 5-Amino PM on top of my AM subq. Can't find factual research in regards to subq being bioavailable/efficacious (some say it is not), therefore hedging my bets. Frustrating. If someone finds reliable info (not a YT influencer...lol) please post and reference? TIA! At the moment, I plan to be on it indefinitely due to the NAD+ recycling benefits, love my NAD.
@PeptidePete I though this Alex Kikel Seminar was decent
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@PeptidePete I though this Alex Kikel Seminar was decent
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@EXTROPIAN If you like that one he has a good Mitochondrial Peptide Seminar (all the good ones) in his video library on his YouTube page too. Most his seminar videos are great lessons.
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This HVY is very potent compared to other 5 am I’ve researched. I had to back down to 5, but also got little bubbles at IS , they eventually go away, but it’s kind of strange. Don’t experience this with other 5 AM such as nexaph.
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@WisGal64 Back down to 5? 5mgs I assume? What did you start with that was too much? I have mine but haven't used it yet. I am thinking after my labor day vacation.
@WisGal64 Back down to 5? 5mgs I assume? What did you start with that was too much? I have mine but haven't used it yet. I am thinking after my labor day vacation.
Yes, 5mg, started at 15 where I normally am, but the jitters oof. Then backed down to 10, still too much, 5 seems ok, no jitters
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@WisGal64 Back down to 5? 5mgs I assume? What did you start with that was too much? I have mine but haven't used it yet. I am thinking after my labor day vacation.
Yes, 5mg, started at 15 where I normally am, but the jitters oof. Then backed down to 10, still too much, 5 seems ok, no jitters
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@WisGal64 @shaqdiesel FWIW, I found my happy place is 30mg. But I’m also a male, 6-2, 190lbs.
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I can't wait to try it. I do not have anything to compare it to though because this will be my first time researching on this product.
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I can't wait to try it. I do not have anything to compare it to though because this will be my first time researching on this product.
@Shaqdiesel This is my first experience as well. Hopefully you’ll like it.
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I prefer oral 5 amino 1q. But just ordered the 500mg bottles. Yes 500mg. 110 a kit. Im pretty stoked about it
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I take 50mg/.5ml of liquid 5amino daily. I don't feel any added energy, but I am testing nmn powder, mots, and nad+ also. I just hope it is fighting the fat.
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