I started at 2mg with no side effects and titrated up as needed every 4 weeks. Down 51lbs since February. I also run tesamorelin for visceral fat and Ipamoralin. For me too not get constipated in the beginning, I Stayed super hydrated. I also take 2 scoops of psyllium husk in a morning protein shake every morning and constipation isn’t an issue.
