@ResearchCat said:

A friend and I keep getting ads and emails for RX prescribed peptides. $279 for 10mg Wolverine and they ship it reconstituted.

I’ll stick with Nexaph, thanks.

Hi,
I was checking this Nexaph vendor for Klow and saw below formulation. it appears GKH-CU is 50MG.KLOW (TB4/BPC/KPV/GHK-cu) 10/10/10/50 (Transparent Blue /. Is GKH-CU 50 MG too high for KLOW formulation?
Ive seen other vendors(Sourced from this site) selling KLOW stack where its reversed BPC/TB500/GHK-CU/KPV - 50/10/10/10 making total of 80GM but BPC is 50MG.
What I am missing here? I understand that in one there is BPC157-50MG and in other its GHK-CU-50MG but isnt there any standard pattern for these stacks?. Please, let me know. Thanks

@pep_researcher said:

Look what I saw at my gym
Hi,
I looked it up after seeing your post. Prices from FlexRx are pretty steep. They surely going to make lots of profit if the hit their sales targets. $169 For Klow. Thanks

@84.brig_tailor said:

Is there a stack/mix that has less of an effect on bowel motility? Preferably still with the glucagon effect.

I would prefer low reta+something for old stock.

Hi,
Based on my limited findings, reta does make you dehydrated, and in order to compensate for that, you need water with electrolytes. such as gateorade, Liquid IV, pedialyte etcetera. Plain water wouldnt do the job. Lastly, for constipation issues, I would use an herbal fiber supplement such as psyllium husk, which is easily available on Amazon, Target, Walmart, etc.

I hope you find this helpful. Thanks!

@seadracos said:

Hi here, I've been using Tirz for about 3 months now and was thinking of switching from a weekly dose to a 5 day dose since the half life is 5 days.

My hope is that this week curb some of the food noise I've started to have at the end of the week while remaining on my low dose. I'm aware that this will up the amount I take per month.

I think I'll give it a try and if it doesn't work I'll just titrate up a bit like normal. I'm at the baby dosages still so I have room to do that.

Had anybody else tried this or something similar?

Hi,
I have also been on tirzepatide since July and am currently taking a 5 mg dose (Mon–Sun). I start to get hungry on Fri–Sun as well, though I try to eat healthy.

There are more knowledgeable people here who will share more and better opinions, and I am not too sure about the 5-day dose protocol. However, since I am in a somewhat similar situation as you, here are the options I am considering (you could try the first two and see what works best):

Option #1: Simple and straightforward—just increase to the next dose of tirzepatide.
Option #2: Split the dose. For example, at 5 mg, take 2.5 mg on Monday and the remaining 2.5 mg on Thursday (or 3 mg on Monday and 2 mg on Thursday).
Option #3: I am personally debating starting 4 mg of tirzepatide and 1 mg of retatrutide starting this monday to kill the trying reta itch.
Let us know whatever works for you. Thanks

@Randy said:

If noise is the issue tirz is king. Titrate to max would be my vote. Ive run both. Glucagon increased my rats hunger

Yes, I'll probably stick to tirzepatide long-term. Food noise is still an issue, and I've plateaued on my current dose, so it's time to up it anyway. Thanks for reply.

@pep_researcher said:

Yeah my did it. But it didn't notice much difference. Was probably suffering from another condition that got detected on its comprehensive blood work, and when it started supplements to fix that, it started losing weight while eating proper meals while on medium dose Reeta.

would you care share more detials. like what before/after dose your rat was on for both Triz and Reta. whats medium reta dose. Thanks

@Justdabbling said:

I was debating the same thing but then i read about people stopping a glp only to have it be less effective when they go back to it later. So now Im thinking if I start reta, I'll probably stack it. Also, I just added the chengdu elora to stack the tirz, so might be a while before i touch the rt i have also bought

Same here. I am also curious to know. If someone tries Reta and decide to switch back to Tirzepatide later, will their previous effective dose of Tirzepatide still work? Or does trying Reta build up a tolerance that makes Tirzepatide less effective afterward? There are mix opnions and experiences out there that does make sense probably due to different body compositions/chemistry. Thanks

@MmmmYah said:

@chrisd said:

I would stop Tirz....and your next scheduled injection...Inject Reta instead... Thats what I'm going to do... I was at 7.5 Tirz but will start Reta at 1 mg mainly because I had a bad experience with Reta back in April ...I think I titrated up too fast and it gave me panic attacks.. I was new at peptides and self injections and made some beginner mistakes, Tirz has been great...I've lost 30lbs since april but have been on a Plateau since Sept...time for a change

Any reason why you are switching earlier rather than titrating all the way up to 15 mg Tirz first?

No specific reason, I’ve just been seeing so much hype about Retatrutide everywhere lately that I’m really curious to learn more and thats why wanted to try it out. that's main driver behind switch

@rahimbhanji said:

did u store the bottle in the fridge after?

Yes, After Mixing its stored in fridge. I start my day with one Nasal Spray in each nostral. Today would be 2nd day. Thanks

Hi Guys,
I have a question for the community: has anyone here tried Retatrutide while on Tirzepatide? If so, what were the dosages, results, and side effects, if any?
Also, if you were already on a certain dose of Tirzepatide, did you reduce it when you added Retatrutide? If so, what were the doses for both the dual (2P) and triple (3P) agonists?
I am currently on Tirzepatide (2P) at 5 mg and plan to start Retatrutide (3P), but I can’t decide between two options:

1. Stop the 2P altogether and start Retatrutide at its starting dose(1mg).
2. Lower the doses of both, for example reducing Tirzepatide to 4 mg and starting Retatrutide(1mg) alongside it.
   Has anyone been in this situation? Please share your experience. Thank you!

@bobs said:

Nothing you wrote suggests the product you got is bad. If you are unsure, test one vial yourself in a lab you trust. It will likely show up good.

Please, pardon my ignorance. Not that I plan on doing that. But just out of curisoty and for my learning what lab one can take their vile for testing. Are you referring to regular Blood work labs like labcorp, qwest etc? Thanks

Sorry I meant to say 20MG and then 1 nasal spray (12 Units) would make it .8mg of peptide dose = .8+.8 = 1.6 mg. Thanks

Hi,
I've Ordered from Studz Peptides Standard Semax+Selank 10MG peptide. It came with Peptide 10MG/3mL Vile and Saline. I mixed with 3ML Saline and then poured into nasal spray. Took one spray in each nostral and didnt see any noticable affect. I was under the impression one will get mental clarity but I didnt. It could be due to lose dose (nasal Spray). Spary bottle say each spray is 12 units which is .4mg of both. Not sure if I did anything incorrectly. But I am sharing my experience. May be I Should've mixed with 2ml of water. Thanks

Thank You all for your comments and also sharing link much appreciated. Thanks again

Hi Team,
I am newbie and it was my first try to reconsitute RUO Peptides. However, after wataching videos on this forums and reading several posts. I believe I mixed them peptides correctly with 3ML BAC Water. Below are the Detials
Peptides Vendor = Crush
3P Agnoist = 10MG in 3ML Vile
Wolverine Stack = 10MG in 3ML Vile
Hospira Bactereostatic Water = 30mL
3ML Syringe - Online
Alcohol Pads -Online
I used below Formula
Concentration = 10MG/3ml = 3.3mg/ml
Standard insulin Syringe = 1ml = 100 Units => 10/100 = 0.1ml
10 Units = 0.1 ml, 10 Units = 0.2 ml & 30 Units = .3 ml
10Units = .1ml*3.3mg/ml =.33 mg
20 Units = .66 mg of 3P Agnoist & W.Stack
30 Unit = .99 mg of 3P Agnoist & W. Stack
I plan on starting Researh on Reta as early as Next Monday with Starting Dose of rougly ~.99mg. Currently I am on 5mg Tirzepatide that I will stop. Any suggestion, advices, comments. Please, let me know I am all ears and eager to learn. Thanks In advance
Lastly, I’m not sure how much of the W. stack to use as a starting dose for research. Any suggestions would be appreciated. Thanks

Welcome from Fellow Newbie!

Hi All,
I’m new to peptides and glad to be here. I started tirzepatide in July 2026 for diabetes, and I was really impressed with my lab results. That got me curious about peptides more broadly.

I’ve been reading online and watching YouTube, and I started an Excel cheat sheet to keep my own notes organized. When I went looking for reliable sources, I found that most places had too many filters and a lot of conflicting information. I came across this community through a search on Claude AI, and it feels like a real find. The depth of knowledge and the sources people share here are exactly what I was looking for.

Thank you for building such a helpful space. I’m looking forward to learning from you all and contributing where I can.
Regards,
Zack

I’m researching a possible switch and wanted to hear from anyone who has actually done this sequence: starting on tirzepatide, moving to retatrutide, then returning to tirzepatide. I haven’t tried it myself, so I’m hoping to learn from people who have. How did your A1C and weight change after each move, and did tirzepatide work as well the second time around? I’m also curious about side effects, bloodwork like lipids and liver enzymes, energy and sleep, and whether you had to restart at a lower dose when you went back. If you can share your doses, how long you stayed on each, and whether you had labs before and after, that would help a lot. Thanks for any experiences you can share!