@Stevepep - this is not meant to be an anti-peptide post. The things you are mentioning may be true but the story was more about the fact that Mots and any of the GH Secretagogues (not CJC) can cause histamine reactions which for some people can lead to Anaphylactic shock.

I also shared more than one story of people who faced close calls in reactions to these peptides. I became aware of the potential reactions to Mots after starting research on my Rat. I was completely unaware that GH Secretagogues could also cause a similar reaction.

I am assuming I am not the only one who was unaware of some of these risks and the purpose is to share information for those of us who are less enlightened.

There are risks to researching with peptides. I think its important to understand as many of those risks as possible so that we can make informed decisions and keep our rats safe.

There is a news story making the rounds that actor, Richard Hanson had a Anaphylactic response to injecting CJC + IPA and subsequently passed away.

https://www.usatoday.com/story/entertainment/movies/2026/10/30/richard-norton-cause-of-death-peptide-injection/92519001007/

There are no details yet that I can find indicating where the Peptides came from. They appear to have 'prescribed' by a Health Practitioner etc...

There is some indication that Richard was doubling his dose, which might have also been the problem. Some simple Ai searching did reveal that a CJC+IPA Dose could cause an Anaphylactic response.

This is not the first time I have heard about Anaphylactic reactions to a peptide injection. I have seen more than one post from a user claiming to have experienced anaphylactic shock from a peptide injection. One of them from You Tuber Vigorous Steve who had a reaction to a mega dose of Mots-C and had to be rushed to emergency. The other story was from an Instagram guy who just happened to have an epi pen handy but was also hospitalized.

For those of us with only the best interest of our research lab rats in mind, has anyone considered keeping an Epi-Pen handy..,, in a case where your test rat has a Anaphylactic reaction to a research dose of a peptide.

I know we have a couple around the house for my wifes allergies. I think I am going to become a little more acquainted on how to use it.

Just thought I would add a message from Vigorous Steve on the subject:

Steve's Warnings to the Community

Following the incident, Steve strongly urged caution with research peptides, noting that MOTS-c and growth hormone secretagogues are known to cause severe histamine and anti-drug antibody reactions. He strongly advises against large single doses or rushing injections, emphasizing instead the necessity of consulting medical professionals and understanding the high risk of severe systemic sensitivities associated with these substances.

@Randy ....well that's pretty cool

Thanks

@Stevepep - interesting. Well, that's your experience with the Savvio, so it is what it is. I haven't had that problem with them yet.

I can understand and appreciate supporting Randy. If I lived in the US I would do it more.

I have been on tons of peptide forums and this one is fantastic. Also learned a ton....I never thought I would be spending so much money on syringe filters!!

@Randy - Im jealous! Post pics when you get them.

Found the baby blue pen for $259 to ship from Germany

https://everymarket.com/products/humapen-savvio-blau

@Stevepep - can you elaborate on what you think the differences are between the intended purposes of a pen like the Savvio (insulin injections) vs Research Dosing.

Up to now, I find the Savvio pens to be fairly resilient and still very accurate as far as dosing is concerned.

I'm with you on the auto pens... in my experience they just don't hold up. Might be ok for once a week researching but not worth the extra $

@mrjoshua44 - I think it might worth trying one of them. I know DaroPep carries them.

They are unique pens in so far as there is no clicking sound when pressing down on the plunger. I imagine some people won't be fan of that.

ALSO

I think the metal push rod is useful if you plan to move more viscous liquids through a needle.

Thanks for the feedback and opinions gentlemen. I did some Googling about which seems to concur with your opinions.

@researchcat - Frank the research rat started on a super low dose, so I don't think he needs to do that. I'll probably give Frank the Research Rat a 2mg dose to start and then titrate up

@Randy Thanks

I haven't made the move to Niimbot or thermal transfer yet

More specifically How did you create this label ?

It doesn't look like a Thermal Transfer label. Those look like they are on a sheet, not a roll ? Don't Niimbot only print on labels that are on a roll ?

You also have a minimum of three colors on that label (Blue, Black and Grey)

Could just be my limited knowledge on how Niimbots work

So my research rat, Frank, has to prep for some minor knee surgery.

He has been researching a GLP for 8 months now and has been directed to stop for 4 weeks

In about 4 weeks Frank the test rat will be cleared to research a GLP Protocol

In terms of research doses

Does he pick up where he last left off (2 x 4mg/week)

OR

Does he start with lower research dose from where he left and titrate up

Cheers!

@Randy Those Labels in the pic look amazing !!

Those aren't from the Niimbot, right ?

Did you have those printed professionally ? How did you make those ?

Here is my 'collection'

As you can tell, I was a big Gansulin fan at first but in my experience they start to go funky after a while. The auto mechanism seems to slip and I have found that the accuracy is not great on them. I don't use them anymore, but I can't bring myself to throw them out.

I test all of my pens on a Milligram scale for dosing accuracy and the Lilly pens are consistently the best with the Exception of the Luxura...which seems to be their least accurate pen of the ones I have tried (Luxura, HumaPen Ergo 2, HumaPen Savvio).

I am based out of Canada and the pharmacies here give the Savvio pens away for free when you use Eli-Lilly insulin.....I don't buy insulin, but there is a small pharmacy that sells the Savvio pens on Amazon for about $28 USD ($40 CAD). That's why I have so many of the Savvio's (top row, Red and Grey pens). They are cost effective and they are consistently dead on accurate with dosing. They don't have any clicks, so its just a silky smooth . If you like little clicky sounds the Savvio is not for you. I also like that the Savvio's have a metal push rod on them. The Ergo 2's (top row, left side) are nice as well if you like that clicky sound and feel.

I have a couple of AliExpress pens featured in the lower row. The big white one feels like a cheap piece of crap.....but it is surprisingly accurate. I don't like to use it because it just feels gross. The light blue one in the lower row with the Thymasin Label on it is an excellent Manual pen off of Ali Express. I threw out one of the Ali Express pens because it was so bad.

Also got a couple of Amazon pens (Gold and Black on the lower row, left side). They feel ok'ish. Not super accurate but useable if I'm in a pinch.

I have Randy's Xulin Pen 3 (Bottom Row, Red Pen on the right)which has the sweetest feeling click mechanism of the bunch. I can see why it is one of his favourites.

Day 1 - Started the research first dose of Slim Assist on my Lab Rat....Mike at about 10:30 AM Today.

Diluted with 0.8ml of Hospira

First dose seemed to have gone smoothly. Mike did not complain of any site reactions or discomfort etc....his next dose will be 1mg next Tuesday.

Mike the Rat worked out shortly after his first research dose.

As one might expect, nothing of note happened.

Like much of the rest of the world, we have a Hospira BAC shortage in the Great White North. Some on line Pharma's have them but have a limit of two per person....and wouldn't you know it, 2 units doesn't meet their minimum shipping threshold. I bumped up my purchase with the Sodium Chloride BAC. After some quick AI'ing around, seemed like a viable alternative for the right peps.

Has anyone tried Reconstituting their research peptides with Hospira 0.9% Bacteriostatic Sodium Chloride (30 mL)

Theoretically speaking it might help to lessen the sting from Peptides like Mots-C

I heard RETA was a hard no

Anyone else have any experience or knowledge in this area ?

@TBone - thanks for the heads up - managed to get two orders together. 40 weeks of supply.

Should last a year with the odd off cycle thrown in every once in a while

@vpeptides - that makes more sense. That was a great deal offering. I was going to order it...oh well...you snooze you lose

If you could manage to order that Deal you posted, 3 x's, you would be buying 60 weeks at 5 mg /week for a little over $2500

@vpeptides - I guess its kind of moot given that they sold out

Buying 10 single units +15 Free, yields a better per mg price than buying 10 double vials + 15 single vials free

@vpeptides

If I am interpreting the promotion correctly, it is cheaper to buy the 10 of the singles and get 15 free

But it doesn't matter really, because they are sold out now ...lol!

@vpeptides - I was just going to post this as well.

I think the math per mg works out better than the recent 50% off sale they had on the 5mg FLGR-242 bottles.

If you are buying 10 bottles of Slim Assist Singles at $62.50/bottle, you also get 15 bottles of Slim Assist free.

So you are getting 25 vials of Slim Assist for $625.50 - 15% Jay Discount = $531.25

2 mg of FLGR242/Vial x 25 vials = 50mg of FLGR = $10.63/Mg of FLGR-242

If taking a 5 mg dose per week, that's $53.13/week which fairly reasonable if it does what it's supposed to do.

It's a 10 week supply , but if your partner or loved one orders as well, you can at least double that amount