Skip to content
  • Categories
  • Recent
  • Tags
  • Popular
  • World
  • Users
  • Groups
Skins
  • Light
  • Brite
  • Cerulean
  • Cosmo
  • Flatly
  • Journal
  • Litera
  • Lumen
  • Lux
  • Materia
  • Minty
  • Morph
  • Pulse
  • Sandstone
  • Simplex
  • Sketchy
  • Spacelab
  • United
  • Yeti
  • Zephyr
  • Dark
  • Cyborg
  • Darkly
  • Quartz
  • Slate
  • Solar
  • Superhero
  • Vapor

  • Default (Zephyr)
  • No Skin
Collapse
Peptide Critic Community

Peptide Critic Community

  1. Randy the Rats Research Forum
  2. Peptide Discussion
  3. Klotho / FLGR242 (albumin-bound new tech)
Prize
Red, White & Blue V2 Pens
Ends in
8161 entries · 1000 participants
Enter →

Klotho / FLGR242 (albumin-bound new tech)

Scheduled Pinned Locked Moved Peptide Discussion
researching
108 Posts 14 Posters 6.9k Views 5 Watching
  • Oldest to Newest
  • Newest to Oldest
  • Most Votes
Reply
  • Reply as topic
Log in to reply
This topic has been deleted. Only users with topic management privileges can see it.
  • quicksilver80Q quicksilver80

    @Stones67 any weird side effects worth note? I feel like they'd be similar to gh

    S Offline
    S Offline
    Stones67
    wrote on last edited by
    #41

    @quicksilver80 sorry. Forgot to hit reply. See above. Or below. Wherever! You'll see it! trial not trail.

    T 1 Reply Last reply
    1
    • S Stones67

      @quicksilver80 sorry. Forgot to hit reply. See above. Or below. Wherever! You'll see it! trial not trail.

      T Offline
      T Offline
      TBone
      wrote last edited by
      #42

      @Stones67 @peptidepete @diegoc Following the thread on Biolongevity Labs. Are you gentlemen still researching with this? And are your results still trending in the right direction?

      I saw Josh Holyfield just released a video on YT today that wasn’t necessarily positive. Obviously one needs to take the opinion of a market competitor with a grain of salt. I know each of you are pretty active in this space and I view your anecdotal research as legitimate information.

      I’ve been waiting on a sale to make this purchase. It is substantial for me, but worth it if it works as intended. TIA

      1 Reply Last reply
      1
      • P Offline
        P Offline
        PeptideEd
        wrote last edited by
        #43

        @tbone If memory serves... Josh Holyfield was speaking about FLGR242, not Klotho. Just want to make sure I didn't miss some detail. Klotho is more interesting to me right now than FLGR242, because most of the things I'm interested in athletically require strength to weight ratio, so I'm not hugely interested in packing on muscle... more building up strength and maintaining a light (but healthy) muscle mass 🙂

        P quicksilver80Q 2 Replies Last reply
        2
        • P Offline
          P Offline
          PeptidePete
          wrote last edited by
          #44

          As noted in previous threads I have been on it continually since it was introduced to the market at the end of december. The past several months have been 1 mg per day . Every day. No breaks. I was just thinking the other day I feel like I've probably topped out or maxed out or whatever you want to call it. If you want to look at the research and the charts on the Bimagrumab and if your research leads you to believe that the results for flgr242 can and should be similar, then I'm now entering the time period where that would occur. It makes sense to me that the majority of gains would occur early in the use of the material. As I recall the second and third month or the massive growth phases where I just wanted to work out every day. With all that said I remain of the opinion that I will be on this until some other kind of myostatin inhibitor that is better comes down the line. My lean mass gains and fat loss are inarguable, and at my age the muscle gain by conventional wisdom is not possible. Now I don't know who this Josh guy is and I don't trust anybody all I trust is my own research because everybody is conflicted. So I would urge anyone to do their own research and make their own determination and I think the facts of the matter will become crystal clear to them. If I've not already said this, results don't occur overnight they don't occur within a week and they only start to occur within a month I think anyone who is serious about researching this material should not do so unless they have every intention to do it for 3 months straight. So there's some food for for you 👍

          1 Reply Last reply
          0
          • P PeptideEd

            @tbone If memory serves... Josh Holyfield was speaking about FLGR242, not Klotho. Just want to make sure I didn't miss some detail. Klotho is more interesting to me right now than FLGR242, because most of the things I'm interested in athletically require strength to weight ratio, so I'm not hugely interested in packing on muscle... more building up strength and maintaining a light (but healthy) muscle mass 🙂

            P Offline
            P Offline
            PeptidePete
            wrote last edited by
            #45

            @PeptideEd said:

            @tbone If memory serves... Josh Holyfield was speaking about FLGR242, not Klotho. Just want to make sure I didn't miss some detail. Klotho is more interesting to me right now than FLGR242, because most of the things I'm interested in athletically require strength to weight ratio, so I'm not hugely interested in packing on muscle... more building up strength and maintaining a light (but healthy) muscle mass 🙂

            Klotho is very subtle. I believe I noticed it, I believe it had and has noticeable benefits, and I believe like flgr242 it's something that you need to plan on using until something better comes along and that may be years from now . It's not a one hit wonder, it's not you do one or two vials and then you're one and done . If you're older and you're deficient that's just the fact of the matter and you're going to be using it until the day you die or something else comes along . That's my personal opinion of course but it's also backed up by science in regards to age deficiency. It's anecdotal and not 100% direct but I do have frequent Labs run, kidney function is perfect and I do some other materials that are somewhat stressful on the physiology 😉 so that's somewhat of a objective measure. I also use cystatin C as my testing not the usual egfr which if you're using creatine at higher levels as I am can affect regular egFR. So be a careful and smart researcher. Bottom line I'm still on it and I plan to be on it as I said , it's not something that you want to cycle it makes no sense to do so. Hope that helps 👍

            1 Reply Last reply
            1
            • P PeptideEd

              @tbone If memory serves... Josh Holyfield was speaking about FLGR242, not Klotho. Just want to make sure I didn't miss some detail. Klotho is more interesting to me right now than FLGR242, because most of the things I'm interested in athletically require strength to weight ratio, so I'm not hugely interested in packing on muscle... more building up strength and maintaining a light (but healthy) muscle mass 🙂

              quicksilver80Q Online
              quicksilver80Q Online
              quicksilver80
              wrote last edited by quicksilver80
              #46

              @PeptideEd his most recent video basicly boils down to saying it inhibits one of two factors needed for that ridiculous rat study to track with humans. Which it misses out on activin a reduction? My response in my mind was. So stack ace031 and flgr242? Sorted

              P 1 Reply Last reply
              2
              • quicksilver80Q quicksilver80

                @PeptideEd his most recent video basicly boils down to saying it inhibits one of two factors needed for that ridiculous rat study to track with humans. Which it misses out on activin a reduction? My response in my mind was. So stack ace031 and flgr242? Sorted

                P Offline
                P Offline
                PeptidePete
                wrote last edited by
                #47

                @quicksilver80 said:

                @PeptideEd his most recent video basicly boils down to saying it inhibits one of two factors needed for that ridiculous rat study to track with humans. Which it misses out on activin a reduction? My response in my mind was. So stack ace031 and flgr242? Sorted

                Thank you for posting with those comments, as I didn't see that video or what this guy said. See this is the problem there is so much b******* out there promulgated by people who were conflicted. It just pisses me off because you can't trust anybody, especially people doing YouTube videos because there's maybe 1% of people who are not conflicted and therefore giving you bad information. It really pisses me off.

                Flgr242 in arguably incontestably works. End of story I don't give a f*** what somebody's guesses and ideas are, I know what it did for me and it did things that nothing else in my life ever did for me with zero negative side effects. If you're an older person and you want to counter the effects of sarcopenia in combination with a proper lifestyle, for me no sugar no carbs no vegetables and a pretty strict carnivore diet, the myostatin inhibitor is absolute pure Magic . This Josh fellow can go screw himself with his b******* . I got zero patience for this crap.
                A side note I just thought about, I had a tumor in one of my sinuses that I had to have radiation treatment on 3 years ago because it was not accessible for surgery without actually cutting bone out , and I wasn't going to do that. I just had a three and a half year follow up with my radiation oncologist to review my latest MRI. This is subsequent to using the flgr 242 and being on growth hormone and a variety of other fun and interesting peptides, the tumor is completely gone no regrowth and my radiation oncologist was tickled pink with how I looked, said I looked jacked . I assure you never in my life has anybody told me I ever looked jacked 😁 that was 100% flgr242 , because I never looked jacked from simply being on Carnivore for three and a half years . There's a data point that anyone that wants to can put in their pipe and smoke it 😂

                quicksilver80Q 1 Reply Last reply
                1
                • P PeptidePete

                  @quicksilver80 said:

                  @PeptideEd his most recent video basicly boils down to saying it inhibits one of two factors needed for that ridiculous rat study to track with humans. Which it misses out on activin a reduction? My response in my mind was. So stack ace031 and flgr242? Sorted

                  Thank you for posting with those comments, as I didn't see that video or what this guy said. See this is the problem there is so much b******* out there promulgated by people who were conflicted. It just pisses me off because you can't trust anybody, especially people doing YouTube videos because there's maybe 1% of people who are not conflicted and therefore giving you bad information. It really pisses me off.

                  Flgr242 in arguably incontestably works. End of story I don't give a f*** what somebody's guesses and ideas are, I know what it did for me and it did things that nothing else in my life ever did for me with zero negative side effects. If you're an older person and you want to counter the effects of sarcopenia in combination with a proper lifestyle, for me no sugar no carbs no vegetables and a pretty strict carnivore diet, the myostatin inhibitor is absolute pure Magic . This Josh fellow can go screw himself with his b******* . I got zero patience for this crap.
                  A side note I just thought about, I had a tumor in one of my sinuses that I had to have radiation treatment on 3 years ago because it was not accessible for surgery without actually cutting bone out , and I wasn't going to do that. I just had a three and a half year follow up with my radiation oncologist to review my latest MRI. This is subsequent to using the flgr 242 and being on growth hormone and a variety of other fun and interesting peptides, the tumor is completely gone no regrowth and my radiation oncologist was tickled pink with how I looked, said I looked jacked . I assure you never in my life has anybody told me I ever looked jacked 😁 that was 100% flgr242 , because I never looked jacked from simply being on Carnivore for three and a half years . There's a data point that anyone that wants to can put in their pipe and smoke it 😂

                  quicksilver80Q Online
                  quicksilver80Q Online
                  quicksilver80
                  wrote last edited by quicksilver80
                  #48

                  @PeptidePete eh i would watch the video. Hes not exactly greg doucette rage baiting it. Hes just saying theres not enough information or positive studies to 100 percent confirm or deny the effects. Its so new i kinda agree in that regard. I mean 10 to 15 years ago i remember most of the guys my age saw growth hormone like witchcraft. Now fast forward every balding gym bro is pushing 2 to 5u like its b12 or something. Just needs time like every other new drug.

                  P 1 Reply Last reply
                  3
                  • quicksilver80Q quicksilver80

                    @PeptidePete eh i would watch the video. Hes not exactly greg doucette rage baiting it. Hes just saying theres not enough information or positive studies to 100 percent confirm or deny the effects. Its so new i kinda agree in that regard. I mean 10 to 15 years ago i remember most of the guys my age saw growth hormone like witchcraft. Now fast forward every balding gym bro is pushing 2 to 5u like its b12 or something. Just needs time like every other new drug.

                    P Offline
                    P Offline
                    PeptidePete
                    wrote last edited by
                    #49

                    @quicksilver80 said:

                    @PeptidePete eh i would watch the video. Hes not exactly greg doucette rage baiting it. Hes just saying theres not enough information or positive studies to 100 percent confirm or deny the effects. Its so new i kinda agree in that regard. I mean 10 to 15 years ago i remember most of the guys my age saw growth hormone like witchcraft. Now fast forward every balding gym bro is pushing 2 to 5u like its b12 or something. Just needs time like every other new drug.

                    My n = 1 and diligent and deep regular testing is all the information I need. Thanks for the additional info on the video I may actually have this guy blocked on youtube, I'll have to look him up and watch it and see what he has to say. I have nothing to sell to anybody except for truth and the strongest possible suggestion that anyone form their opinions based on nothing other than their own research. It seems like everything except for the tiniest percent is nothing more than propaganda or a psyop 🤔😁

                    1 Reply Last reply
                    1
                    • T Offline
                      T Offline
                      TBone
                      wrote last edited by
                      #50

                      Thank you gentlemen! This was precisely what I needed to hear. I truly value your input and appreciate the community here at Peptide Critic!

                      1 Reply Last reply
                      2
                      • S Offline
                        S Offline
                        Stones67
                        wrote last edited by
                        #51

                        I'm another N=1. I'm 59yo. I'm exactly at 3 months since starting FLGR (no Klotho) and without a doubt have recorded visible changes in my physique that would not have occurred without running gear. Labs done after a month were all improved (fasted glucose, A1c, etc) but at the time was also running reta at 0.5mg every 6 days. Next labs in about a month and I may not be able to stop myself from adding a repeat Dexa (my curiosity is getting the better of me). I believe it (flgr) is allowing me to move beyond my myostatin regulated genetic potential. My testosterone is optimized with enclomiphene and I enjoy CJC/Ipa. The grey hair not withstanding, I look and feel closer to 40. But this is a speculative play. Not in terms of results, as I can honestly vouch for those now, but in terms of safety. I have enough stocked away for another year but am considering running this for another 3 months or so, and then taking a few months off. I'm honestly curious about the durability of results. I think Pete will still be on the stuff when he croaks at 150! Only buy when on sale (I don't buy anything else on BLL cuz all their stuff is crazy expensive) but shoot for at least 6 months. I wouldn't be surprised if they do something enticing over the 4th. Someone else is going to eventually reverse engineer the albumin binder part or figure out another way to extend half-life. The monoclonal antibody stuff is intriguing and I'll take my cues from quicksilver as he formulates his thoughts over time. Or go to Panama or the Bahamas or wherever and have your genes altered! Otherwise it's PED's or FLGR as far as I can tell! I watch Josh H. and think he does OK making AI research sound like his own. Unfortunately there is no real research on this new stuff so unless he tries it for 6 months he really doesn't know anything. Hope that helps and happy to chime in anytime!

                        1 Reply Last reply
                        2
                        • P Offline
                          P Offline
                          PeptidePete
                          wrote last edited by PeptidePete
                          #52

                          I just watched the video that's 15 minutes of my life I'll never get back. Look here's the bottom line I'm not going to waste any time on this if you're researching this material and you do not clearly understand the four different follistatins being discussed then you don't know what you're doing and you need to do better homework. Number one gene therapy number two monoclonal antibody number 3 injected directly into the muscle number four flgr242 albumin bound. Four completely different conversations if you don't understand that you need to dig deeper. This video was a pile of garbage and struck me as nothing more than hit piece and an attempt to appear intelligent when in fact he made himself out to be absolutely ignorant on the topic at hand. Let me be crystal clear I have an extremely hard time stomaching Jay Campbell I'm no sycophant for bio longevity labs . I'm a researcher I'm a serious researcher and I care about what works and what has minimum or no side effects. If you're looking if you're looking at this material dig deep. I'm not a gym rat, I'm not a bodybuilder, I have no tattoos I have no piercings and I'm sure as f*** not selling coaching. An absolute perfect example this video is of buyer beware and taking the time and making the effort to understand what it is that you're talking about.

                          Ps- I'm doing all of my post today using voice dictation on my phone so they're formatted like I'm a moron 🤣

                          1 Reply Last reply
                          3
                          • P Offline
                            P Offline
                            PeptidePete
                            wrote last edited by PeptidePete
                            #53

                            Stones 67, thank you for your post very interesting! Nothing in my previous post was oriented towards you whatsoever just to be clear on that. I appreciate you sharing your journey and your personal viewpoints it's helpful to everyone and I very much enjoy reading your post 👍😊

                            S 1 Reply Last reply
                            0
                            • quicksilver80Q Online
                              quicksilver80Q Online
                              quicksilver80
                              wrote last edited by quicksilver80
                              #54

                              Yeah i also dont take any of this personally. Just having a interesting conversation with stuff weve all seen that may or may not argue the opposing side. Thats kinda how i research. I dont look at it as how is he wrong but where are the holes in my ideas. Guess doing that to other peoples videos can be seen as strange though hopefully noone took me as antagonistic or inflammatory

                              1 Reply Last reply
                              1
                              • P PeptidePete

                                Stones 67, thank you for your post very interesting! Nothing in my previous post was oriented towards you whatsoever just to be clear on that. I appreciate you sharing your journey and your personal viewpoints it's helpful to everyone and I very much enjoy reading your post 👍😊

                                S Offline
                                S Offline
                                Stones67
                                wrote last edited by
                                #55

                                @PeptidePete Didn't even cross my mind that you were speaking to me directly. We are all good. I like this topic and greatly enjoy the discourse! Glad there's a couple folks on here either already well along in their journey or doing a deep dive to see if it sounds right for them. I can tell you know your s**t. I value your insights (and quicks!) and read your comments with interest.

                                1 Reply Last reply
                                1
                                • P Offline
                                  P Offline
                                  PeptidePete
                                  wrote last edited by
                                  #56

                                  Thought of some strings I'd highly recommend curious folks to pull on:

                                  1. The gene therapies for all their promise seem to have not worked well. Poor results. Both minicircle and plasmid.
                                  2. As always happens grifters are identified- Adeel Khan (no surprise).
                                  3. The inventor of FLGR242 and a-Klotho MAB, Mike Farber, is worthy of a deep dive, I like everything I see and hear.
                                  4. My wife (petite) has been on FLGR for 4 months now at 2mg once per week and she has gone from having ZERO desire for variable resistance workouts to being a little workout monster and looks great.
                                  5. The monoclonal antibodies aside from being simply unattainable have in most cases quite serious unwanted side effects.

                                  I thank my lucky stars I immediately recognized the value on offer when the two MAB (Modified Albumin Binding) agents were introduced by BLL last year, Mike Farber is in the same situation I am, aging and wanting some good, REAL, solutions. He eats his own cooking. I'm so thankful he is who he is. That's all for me for a while because I sound like a paid shill, but I am a PAYING shill...lol. Dig deep my friends, trust no one. And never ever forget when you are reading or watching something, "THEY" want you weak and compliant, I'm shocked FLGR/a-Klotho can still be bought. Do your homework, be the absolute best you can be.

                                  1 Reply Last reply
                                  3
                                  • R Online
                                    R Online
                                    ResearchCat
                                    wrote last edited by
                                    #57

                                    I am going to vote this thread the most expensive thread in peptide history. Congratulations on wiping out all my savings since joining this forum.

                                    Please set a funny and sarcastic signature line. It brings me joy. Thank you for your attention in this matter.

                                    P T 2 Replies Last reply
                                    0
                                    • R ResearchCat

                                      I am going to vote this thread the most expensive thread in peptide history. Congratulations on wiping out all my savings since joining this forum.

                                      P Offline
                                      P Offline
                                      PeptidePete
                                      wrote last edited by
                                      #58

                                      @ResearchCat said:

                                      I am going to vote this thread the most expensive thread in peptide history. Congratulations on wiping out all my savings since joining this forum.

                                      😂

                                      My SS-31/Sturgeon roe posts perhaps come in at #2?

                                      LOL 😀

                                      The price of vigor and vascularity!

                                      1 Reply Last reply
                                      1
                                      • V Offline
                                        V Offline
                                        vonendorphin
                                        wrote last edited by
                                        #59

                                        This is interesting, but both users in this thread have confounding compounds and may be more motivated at the gym by placebo effect. Would love to see graphs from stats, labs and workout trackers to see if you are beating what would be considered normal gains.

                                        S 1 Reply Last reply
                                        0
                                        • P Offline
                                          P Offline
                                          PeptideEd
                                          wrote last edited by
                                          #60

                                          @peptideed speaking of your sturgeon roe posts… could you expand on (or at least point out the threads to pull) the reason sturgeon roe instead of sockeye salmon roe?

                                          P 1 Reply Last reply
                                          0

                                          Hello! It looks like you're interested in this conversation, but you don't have an account yet.

                                          Getting fed up of having to scroll through the same posts each visit? When you register for an account, you'll always come back to exactly where you were before, and choose to be notified of new replies (either via email, or push notification). You'll also be able to save bookmarks and upvote posts to show your appreciation to other community members.

                                          With your input, this post could be even better 💗

                                          Register Login
                                          Reply
                                          • Reply as topic
                                          Log in to reply
                                          • Oldest to Newest
                                          • Newest to Oldest
                                          • Most Votes


                                          • Login

                                          • Login or register to search.
                                          • First post
                                            Last post
                                          0
                                          • Categories
                                          • Recent
                                          • Tags
                                          • Popular
                                          • World
                                          • Users
                                          • Groups