Tesamorelin Research Dosing Protocol
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What is the NAD+ for? I don’t know your history or goals, but almost think that MOTS-C might be more effective if you are trying to burn fat, especially if you are exercising.
I see no issues researching NAD+/MOTS-C with a GHRH. You can research Tesa/Ipa/CJC first thing in the morning fasted or an hour before bed after fasting 2-3 hours.
I am not a doctor, or your doctor, but I like to have a specific goal and purpose for whatever peptides I am researching, even if I am researching several at the same time. ;). At the moment, I am much more bullish on MOTS-C than on NAD+ as part of an ongoing maintenance stack.
@ResearchCat NAD+ really kept me on my feet when I first started Tirzep; I still have 4 vials of it and am going to use it. Depending on how I'm feeling when I've used it up will determine if I buy more. When something works, I try not to change it. Problem is that I get relatively wired on it; I have a high stress job, and have trouble sleeping. I've recently reduced the dose, so will see if I can find a sweet spot. Thanks for the ideas! I imagine I will try a number of them before all's said and done.
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If you are suffering a loss of energy while on Tirz, it may be because you aren’t eating enough. I know it is hard to do, but when I was above 7.5 mg tirz, I had to force myself to eat in order to hit my macros. At 10mg, I had no desire to eat at all, so I started lowering the dose.
I am not telling you what to do, but if you can add in exercise, or continue a structured workout program, you will probably find Tesa and MOTS-C to be game-changing additions. IMO, adding these in and not 1) eating enough and 2) exercising, will diminish the potential benefits of using them.
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Also, I totally understand the high stress job thing.
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If you are suffering a loss of energy while on Tirz, it may be because you aren’t eating enough. I know it is hard to do, but when I was above 7.5 mg tirz, I had to force myself to eat in order to hit my macros. At 10mg, I had no desire to eat at all, so I started lowering the dose.
I am not telling you what to do, but if you can add in exercise, or continue a structured workout program, you will probably find Tesa and MOTS-C to be game-changing additions. IMO, adding these in and not 1) eating enough and 2) exercising, will diminish the potential benefits of using them.
@ResearchCat I understand your concern. I'm eating plenty, trust me! I have other considerations, ex: I had an advanced case of Lyme Disease and 3 co-infections that took about 13 years (on & off) to get under control. Somewhere during that process, I lost 5.5' of bowel; to say I have absorption problems is an understatement, plus the MTHFR. There's a long laundry list my 70 yrs has collected. The energy loss started from the very beginning, but love the weight loss results. I think I'm probably taking NAD too many times per week, or too much. I cannot toss peps to the side, unless they're truly making me ill; my budget is so limited. Experimenting right now to find a good mix.
I definitely want to add Tesa and will just have to deal with more experimenting.
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Well, all this just kinda blows me out of the water. I need to get rid of a lot of visceral fat; I mean A LOT. The DEXA was horrible! I'm not that overweight, but the Dr. said, and I concur, it's been there a long time and I was raised on a Southern diet. I'm currently taking Tirzep once/wk on Friday night; nothing to eat since lunch, except very light snack later so stomach's not growling. NAD+ M,W & Sat, mornings upon waking, approx 10 hour fast. I have trouble sleeping and get up at 4:30, so not sure where to fit in Tesa. Question for all, but esp. for @randy Do Tesa and NAD+ work well together? I can cut back on the NAD, but not the Tirzep. I could also stay on lower does of Tesa for longer. What do y'all think?
@Eleanor Instead of Tesa you may want to try Survo with your Tirzepatide first. That with hit your glucagon receptor and cause you to burn fat for energy like a Reta effect. Also I ran 5 amino 1mq when I stalled and it helps with energy by blocking NAD loss
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@Eleanor Instead of Tesa you may want to try Survo with your Tirzepatide first. That with hit your glucagon receptor and cause you to burn fat for energy like a Reta effect. Also I ran 5 amino 1mq when I stalled and it helps with energy by blocking NAD loss
@beachfun Thanks for the idea! Does Survo target belly fat? What vendor do you like to research with? My weight hasn't really stalled, but the belly fat concentration is high. I'm fearful of Tesa because of the possibly of edema and joint pan; both of which I already have because of a desk job. Any additional might be unbearable, esp. at my age (70).
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Want to give a shoutout to Tesa from a 60-year-old male. I have been injecting 1mg Sun-Thurs for 12 weeks (among other things including Testosterone, Reta, GHK-Cu and Semax/Selank). Scan from yesterday showed a drop in visceral fat from 112 cm² to 70.3 cm² (37% reduction). Obviously, the Testosterone and Reta played a part, but I can definitively say it helped me. I'm a big fan. I'm taking a 2-week break and will start another cycle again. Can't say enough good things.
Want to give a shoutout to Tesa from a 60-year-old male. I have been injecting 1mg Sun-Thurs for 12 weeks (among other things including Testosterone, Reta, GHK-Cu and Semax/Selank). Scan from yesterday showed a drop in visceral fat from 112 cm² to 70.3 cm² (37% reduction). Obviously, the Testosterone and Reta played a part, but I can definitively say it helped me. I'm a big fan. I'm taking a 2-week break and will start another cycle again. Can't say enough good things.
What time of day of the injection? Thanks!
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I find it very curious (and awesome btw) that so many older people are experiencing such positive effects from tesamorelin. That tells me a couple things. First, it means the pituitary somatotrophs, even when in advanced age, can still function with proper exogenous help.
Second, that means other GHRH peptide drugs would work on those same people, because if Tesa is working (via GHRH stimulus) then the others must work to some (or full) extent as well.
The ongoing, and previously published tesa clinical data used many older patients, all with what should be a pretty harsh comorbitity all things considered (AIDS & advanced age) and despite this, produced a strong GHRH response from the pituitary. Same with the Sermorelin data from years past as well.
All this and I'm pretty sure the study participants were nowhere near as rigorous with there research as we are in terms of pinning around fasted times. I'm certain that none of the Sermorelin data participants even bothered with this at all (this was an unknown benefit at the time) and I don't think the Tesa participants did either but I'm not certain about that. Imagine how much better the results would have been had they made that a priority in their protocols.
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Want to give a shoutout to Tesa from a 60-year-old male. I have been injecting 1mg Sun-Thurs for 12 weeks (among other things including Testosterone, Reta, GHK-Cu and Semax/Selank). Scan from yesterday showed a drop in visceral fat from 112 cm² to 70.3 cm² (37% reduction). Obviously, the Testosterone and Reta played a part, but I can definitively say it helped me. I'm a big fan. I'm taking a 2-week break and will start another cycle again. Can't say enough good things.
What time of day of the injection? Thanks!
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@rburger01 I’m researching 2mg a day M-F. I use 2ml BAC in a 10mg vial. Daily dosage is 40 units.
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@rburger01
Tonight I am mixing up 4 vials into one cart with 3ml bac water and will research 14 units ~2mg/day.I research first thing after waking up (fasted) and typically don’t eat for 2 hours.
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@neil-mccauley I have researched Serm, Tesa, and CJC/Ipa and I can tell you with 100% certainty they work. I think the reason CJC/Ipa has the reputation and popularity it does is that you start noticing results in weeks, not months. Sermorelin is ‘gentler’ and takes months to notice a difference(great for revenue streams at the T clinic). I am only a few weeks into Tesa and have been injured so I can’t speak to results yet.
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Week 4 of Tesa and my Hume is telling me that my visceral fat index is up. Not sure exactly what that means. Will continue to monitor through the next month as I get back into a full workout schedule. After that will be cycling back to CJC/Ipa.
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I ordered from a vendor and they sent me 'free' sterile water with a note that said we reccomend sterile water instead of BAC. I am confused since I was going to use the 10mg within a week. So watching Randy's video, I should be fine and not have the thickening issue. Is this correct?
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I always use Hospira BAC for my Tes/Ipa and have never had a problem. I did a 12 week course this past winter and I am 4 weeks in on a 16 week course currently.
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I always use Hospira BAC for my Tes/Ipa and have never had a problem. I did a 12 week course this past winter and I am 4 weeks in on a 16 week course currently.
I always use Hospira BAC for my Tes/Ipa and have never had a problem. I did a 12 week course this past winter and I am 4 weeks in on a 16 week course currently.
16 weeks on the same bottle of bac?
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No I go through BAC fairly quickly with all of the other peps I do in that time. Probably from 3 different BACs.
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Just a quick update. I don’t know with certainty that it is from the Tesa, but since starting research, I have noticed not that my hands are swollen, but that they feel kind of swollen, if that makes sense, and my thumbs and wrists have been pretty sore. I’ve generally had more joint soreness as well despite continued KLOW research. I will give it another couple weeks but am likely going to accelerate the move back to CJC/Ipa, which was working very well for me.
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I get a puffy in the finger joints feeling from both, but feel it more so with tesa. It does not make physiological sense unless the GH pulse is higher with tesa. Probably largely my imagination but it's the main reason why I run CJC/Ipa. Never compared Igf levels between the two so who knows.
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