@iMemphis18
My research baby has dealt with KP since birth. Typical treatments like exfoliating and using moisturizers with salicylic acid or urea didnt help at all. Most drs seem to say it is a overproduction of keratin but more recently studies are pointing to issues with skin barrier and systemic inflammation. Since her other issues revolve around autoimmune and inflammation, I decided to investigate peptides that address skin barrier repair, immunity and inflammation. The most effective so far for her has been LL-37 which is an antimicrobial peptide (AMP). We also do cycles of SS-31 for mitochondrial repair, TA1 & thymulin for immune issues, and TB500,BPC157 & KPV to help reduce inflammation. Skin products with ceramides are also helpful in maintain moisture and tightening the skin to reduce outbreaks. We stopped all exfoliating since that can make KP worse by inflaming the area further and possibly introducing infection.
Another peptide route that is being studied is hBD-1, hBD2, (human beta-defensin 1 & 2) which is also a prominent AMP and looks promising from research but I havent been able to source it so far.