@iMemphis18 My research baby has dealt with KP since birth. Typical treatments like exfoliating and using moisturizers with salicylic acid or urea didnt help at all. Most drs seem to say it is a overproduction of keratin but more recently studies are pointing to issues with skin barrier and systemic inflammation. Since her other issues revolve around autoimmune and inflammation, I decided to investigate peptides that address skin barrier repair, immunity and inflammation. The most effective so far for her has been LL-37 which is an antimicrobial peptide (AMP). We also do cycles of SS-31 for mitochondrial repair, TA1 & thymulin for immune issues, and TB500,BPC157 & KPV to help reduce inflammation. Skin products with ceramides are also helpful in maintain moisture and tightening the skin to reduce outbreaks. We stopped all exfoliating since that can make KP worse by inflaming the area further and possibly introducing infection. Another peptide route that is being studied is hBD-1, hBD2, (human beta-defensin 1 & 2) which is also a prominent AMP and looks promising from research but I havent been able to source it so far.

I have been trying to find info on this for a while now. It is pricey, but I am interested in whether anyone has tested it. Currently utilizing SLUPP 332 in a DMSO injectable solution on my "Roo" with good results, but always searching for the next "reliable" good option.

@EXTROPIAN motsc and many of the ampk activators help with insulin sensitivity? Also were in a peptide forum, enhancement is the goal?

Small, dissolvable lozenges designed to deliver specific peptides directly into the bloodstream through the mucosal lining of the mouth. Which peps have been experimented with? Which site did you secure them through?

Just an alternative, can never have too many options. If you go to Janoshik public results and use the search option using Canada, two companies come up. https://public.janoshik.com/

I have some on the way for my old horse knees. Trying to prevent having my other knee replaced.

Based on recommendations, I wanted to browse Champion Peptides, but they had a message about online payment problems and said that they were partnering with Pure Rx Peptides. Pure Rx has a number of peptides that I'm looking for. But there is no COA info. Nothing to backup the quality of their products. Before I leap off the cliff, has anyone used them before?

Just watched a very interesting Video around GLP1s and cartilage that was shared with me. I didn't find it on this site, and thought maybe some would be interested. I'll be honest, I have never dove into the history of GLP1s, GLPs in themselves I find fascinating with all the benefits it has provided me. This video is worth a listen/watch link text

update. no reactions to either aod or the ss31 other than a red dot for ss. lifes good.

https://carolinachemical.com/ has lots of powders

@ResearchCat week 8 of the reta i would say out of anything that ive researched or dealt with personally in a perscribed format. nothing has been this "life changing".

For DEXA scans, check your local university if you have one nearby. Mine does them for $66. Can get a bunch of other tests too. Now I just need to befriend someone there to test my peps... [image: 1777080085128-dexapricing.jpg]

Saturday I found out Aavant had some TB-4, from what I have read on forum posts review say its hard to come by and that TB-500 is readily available, I was very skeptical of ordering from a bot on telegram. The entire order process was surprisingly easy. Monday I received a message from them that my order had shipped. Today (Wednesday) I received my kit. Great pricing as well! Definitely watching them for their upcoming drops. I guess the 3d printer I want has to wait.

I noticed that some vendors are switching to USP61 from USP71 for sterility testing. I'll preface this with... learning still in progress Doesn't this raise a concern? USP71 = 14+ day wait, USP61 = 5 day wait. It seems like they are trading off quality for faster turnaround? @randy your thoughts on this?

@Stan-Douglas said in Freeze vs Refrigerate vs cool dark place: From what I understand as of now... moisture is your enemy for unconstituted [is that a word?] peps. I store mine in the freezer regardless of when I plan to begin using, in the original storage box, sealed in a ziplock freezer bag and now with -- I was reading up on this topic and it was suggested to add silica gel or desiccant packs -- I ordered "Color-Indicating Desiccant Packs for Storage, Rechargeable Silica Gel Packets" on Amazon to throw in each bag. Also advice I tripped across was to let your vials warm to room temp before adding your bac water. I use the packets, had no idea there were rechargeable ones.

@MyB said in Has anyone researched or heard of H-20 ?: Wasn’t on my radar but wow what an interesting peptide. It's definitely caught my attention! The only downside for me is it's an immunosuppressant rather than one that helps train like TA-1, I was on immunosuppressants for 10+ years, and all eventually failed. so I've been on a venture. One that sounds very promising is dnaJP1, studies in Cuba, it's completed phase I and 2, now in an AI guided trial. This one teaches the immune system rather than suppress it. I remain hopeful, but like so many other peptide therapies, it'll probably never see the light of day in my lifetime due to $$$ they want and sponsors. Sighhh

@beachfun https://peptidefox.com/content/mito-stack-protocol

@gym.rat There is very little information on Ahkcu but I am now on my second bottle hair serum with the second half of the 1 gram vial of the Ahkcu. Nexaph sells 5 vial kits

@Randy said How much 5am are you researching? Im on 25mg at the moment. Hey Randy, Sorry, didn’t see your reply. Hubby has surgery last week, and I’m just coming up for air. I’m taking it super easy on 5A1MQ - at about 1.5 mg twice a day. Going up slowly but prob wont go over 10mg daily. I think the higher doses were supposed to be for oral preparations, and I’ve heard of people getting pretty good results at the lower doses. I’m always erring on the side of going kinda low. (eg, currently 1mg Epitalon before bed, and I only do 20-30 days twice a year). Just my thoughts… CM

@ursus that I can't attest to, but on the site it listed the 150 box at 98% purity and then on the coa listed on site in their quality control section it was 95%. And they haven't been going into solution completely like the dragons.