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Peptide Discussion

783 Topics 10.2k Posts

General peptide discussion — compounds, goals, side effects, stacks, dosing, and beginner questions. Tag your topic with the peptide name, your goal, and thread type (2–4 tags).

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  • NAD+ Buffered Dosing

    nad
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    mrjoshua44M
    @jackiee Same day as you do your MOTs-c.
  • Labor Day 2026 Peptide Vendor Sales Roundup

    Announcements
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    @atlas01 I love your kitty. I miss my beautiful black one.
  • Tesamorelin or just jump to HGH…

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    I'm about to switch my lab rat back to cjc/ipa from tesa/ipa. 250mcg Cjc/ipa treated it well, no major water retention, good sleep, good recovery etc. Doing 1mg tesa/300mcg ipa has brought water retention, sore knees and random sleep issues. Not a huge fan of tesa personally. Plus cjc/ipa is typically cheaper. So if cjc/ipa is working I'd say no need to switch to tesa.
  • EZP-3P vs NXP-3P

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    RandyR
    @MyB variance on fills is the one boogy man we have yet to really face in the industry.
  • MORE FDA LETTERS BUT GOOD NEWS

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    @ursus I have actually had this conversation with Jeff Cohen at a conference, and many have patents on the use of the products for specific conditions and for PHARMACEUTICAL USE only. The formulations themselves mostly don't have patents (some do before someone searches AI but the vast majority are incomplete for a reason) because you have to disclose them, so they patent them for specific ailments, conditions, or comorbidities. It's why Coke never patented Coca-Cola because they didn't want to release the recipe. Bottom line, they patent therapeutic uses of the drug itself and continue to add on to those. They copyright the names, which Lilly is going after right now. Not to drone on, but we are already seeing the labs allow for calling something the retailers names as the test result instead of the copyrighted name. There is a lawyer behind that as well. Pharma is careful about lawsuits because if they lose, they are screwed. So they may start lawsuits, but the vast majority settle in an undisclosed settlement.
  • HGH 191AA

    Moved researching other-peptide
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    @ursus that I can't attest to, but on the site it listed the 150 box at 98% purity and then on the coa listed on site in their quality control section it was 95%. And they haven't been going into solution completely like the dragons.
  • A Tale of 2 research subjects - need some input

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    @charletonsmith I'm talking with more and more Tirz and Reta researchers who stall out and have no other alternatives other than to increase the dose fairly substantially, or try a myriad of other supps, etc to break through. Our bodies are made to adjust to such peptides, co-factors, etc. and if all 4 pathways get opened (if Cagri is added) and "burned", it's hard to tell how long one has to wait until they can be used again, if ever, with the same efficiency. IF I had it to start all over again, I would have started with Semi instead of Tirz. Although not as much weight loss, you have 3 other pathways to use once the stall comes AND the majority of people who've reached goal weight that I've spoken with and held it there were Semi researchers, now completely off, or are microdosing with good success. I just know of too many people on Tirz and/or Reta who're stalling, as I am at this point and want to preserve some exit routes. The GIP seems to be really active; not that others are not and I can't prove what I'm thinking but after 6 mo. Tirz (added Survo about 3 mos ago), I'm backing off the Tirz and adding Cagri in hopes of saving the GIP. Cagri is GLP-1 + amylin pathway. Since I'm taking Survo, that's GLP-1 + glucagon pathway; keeping in mind that GLP-1 seems to be much easier to back off of than GIP (anecdotal). Saving the Tirz in freezer for much later, hoping I never need it again. Keep in mind, this is my own research and not suggesting anyone else do it, or that it works but it just appears, even chemically (organic), the GIP is the key to a big lock. My experiment. I hope what I've said above makes sense.
  • MOT-c

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    I did ping them to see what they would say. They wrote back: "For non-GLP's our guarantee is 97 percent." That is all it said, nothing more nothing less.‍️
  • This topic is deleted!

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  • DEFENSINS THE ANTIMICROBIAL PEPTIDES

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    EXTROPIANE
    https://youtu.be/rUrKjBGPxPs?is=sk5PsBnnyBU5yyjp
  • Making DSIP into Nasal spray protocol

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    Snake PepskinS
    Definitely use saline, BAC could sting, but more importantly, it can dry your nasal membranes and cause issues like nosebleeds and diminish inter nasal absorption . There are some people that use it, but it not the best practice. Sterile water or deionized water are also options.
  • Mots-c dosing

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    mrjoshua44M
    3-5mg subcutaneous, 1–3× per week. 4–6 weeks on, 2–4 weeks off. Morning dosing, typically 60–90 min before exercise.
  • Adalank vs selank

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    EXTROPIANE
    I am just as curious. I committed a kit of adamax because there is a few who tried it and liked it. I been researching intranasal and it is not bad. I still have a semax sprayer and haven't touched it. I now been using selank and adamax every other day. On my days off i am still focused and well tempered. I also added cerebrolysin which I take at night. That one is strong and it takes a while for it to taper to get to the sweet spot. I can only describe it as vivid.
  • KLOW - stacking efficacy

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    eurouserE
    @derekg1 i tried site-specific injections before on the wolverine stack, just from my experience, it felt worse in terms of recovery. Thats why i stuck with sub-q in the belly which helped heal a 3 year old knee tendon injury in 3 weeks.
  • More on Labs Reference Standards are the key

    lab-test
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    The whole lab thing is really interesting. I raised this before about reference standards and building a catalogue. Janoshik supposedly has a million dollars in reference standards. Vanguard spent $100,000 just this year on reference standards. How much do you think labs like ILS, Freedom or even Kovera have spent on the most important item to accurately measure a peptide? Do they even have a standard? Or are they just entering the peptide name into the equipment? Kyrsia recently covered this "Vanguard said it uses a reference standard for all of its methods and had accumulated more than $100,000 worth of standards during the previous year alone, stored across multiple freezers, refrigerators and at room temperature as appropriate. That gives some useful context to a line on a laboratory report that most customers probably never think about. A reference standard isn’t simply a generic database entry or a name typed into the instrument. It is physical reference material that has to be obtained, stored and maintained, and for less common compounds it may be expensive or difficult to source. So perhaps another question worth asking a testing laboratory isn’t simply: “Can you test this peptide?” But: “What reference standard are you using to identify and quantify it?” Because the quality of a test doesn’t begin when your vial enters the machine. It begins with what the laboratory has available to compare it against."
  • Adipotide

    Moved researching
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    EXTROPIANE
    @Ttia318i To cut off blood to white fat cells and starve then from oxygen, nutrients and rely on your immune white cells to remove them after they die under oxidation and imflamation? Considering what's is already out there? I would not mess with your immune system for fat loss.
  • Has anyone used the Deadpool stack from Nexaph?

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    @MikeMiranda I got a kit of the Wolverine blend from Nexaph. It's OK, but I like my own blend with KPV instead of Cartalax much better.
  • Survodutide briefly turned cloudy after first refrigatrion

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    Survo doesn't have GIP, only GLP1 & glucagon, whereas Reta has all three. In order to keep from a permanent stall just short of my goal, I've switched to Cagri & Survo, which opens 3 of the 4 pathways, exception is GIP. Hoping if the time comes, the Tirz will still work. Wish I'd done all this differently, knowing what I know now.
  • Healing for upcoming surgery

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    @TheMachinist I would do the TB-500 and BPC-157, minimum .5 mg with maybe some Cartalax. As extropian stated, get plenty of supplements. Sardines have a lot of actual tendons, ligaments,. cartilage etc.
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    @MyB Correct. Photos/videos of the vails in the toaster oven were also shared.